| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ketosis | D007662 | 13 associated lipids |
| Intestinal Neoplasms | D007414 | 2 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Infectious Mononucleosis | D007244 | 5 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Hyperkinesis | D006948 | 11 associated lipids |
| Hydatidiform Mole | D006828 | 3 associated lipids |
| Herpesviridae Infections | D006566 | 4 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemorrhoids | D006484 | 2 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lu R et al. | Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. | 2014 | J. Periodont. Res. | pmid:25340203 |
| Grousseau E et al. | Phosphorus limitation strategy to increase propionic acid flux towards 3-hydroxyvaleric acid monomers in Cupriavidus necator. | 2014 | Bioresour. Technol. | pmid:24365742 |
| Vidrine K et al. | Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. | 2014 | Obesity (Silver Spring) | pmid:23630079 |
| Wei Y et al. | Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. | 2014 | Int. J. Neuropsychopharmacol. | pmid:25618518 |
| Procentese A et al. | Continuous xylose fermentation by Clostridium acetobutylicum--kinetics and energetics issues under acidogenesis conditions. | 2014 | Bioresour. Technol. | pmid:24852648 |
| Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
| Kondo Y et al. | Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. | 2014 | PLoS ONE | pmid:25084468 |
| Vargas JE et al. | Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells. | 2014 | Biochem. Cell Biol. | pmid:25070040 |
| Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
| Shen H et al. | BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. | 2014 | J. Cell. Mol. Med. | pmid:24571310 |
| Karki P et al. | Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. | 2014 | Mol. Cell. Biol. | pmid:24469401 |
| Pérez-Carro R et al. | Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. | 2014 | Clin. Genet. | pmid:23895425 |
| Jin H et al. | Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. | 2014 | J. Biol. Chem. | pmid:25342743 |
| Ferrario C et al. | Modulation of fecal Clostridiales bacteria and butyrate by probiotic intervention with Lactobacillus paracasei DG varies among healthy adults. | 2014 | J. Nutr. | pmid:25332478 |
| Gong Q et al. | [Sodium butyrate inhibits HMGB1 expression and release and attenuates concanavalin A-induced acute liver injury in mice]. | 2014 | Sheng Li Xue Bao | pmid:25332009 |
| Pal A and Dey J | Organogelation by 4-(N-tetradecanoyl)aminohydroxybutyric acids: effect of hydrogen-bonding group in the amphiphile head. | 2014 | J Phys Chem B | pmid:25310731 |
| Miletta MC et al. | Butyrate increases intracellular calcium levels and enhances growth hormone release from rat anterior pituitary cells via the G-protein-coupled receptors GPR41 and 43. | 2014 | PLoS ONE | pmid:25310566 |
| White MK et al. | Rad51 activates polyomavirus JC early transcription. | 2014 | PLoS ONE | pmid:25310191 |
| Katzenmaier EM et al. | Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro. | 2014 | Anticancer Res. | pmid:25275038 |
| Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |
| Nakata S et al. | Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. | 2014 | Int. J. Oncol. | pmid:25017791 |
| Gutiérrez Acosta OB et al. | Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. | 2014 | BMC Genomics | pmid:25012398 |
| Farkas O et al. | Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system. | 2014 | J. Anim. Sci. | pmid:24987069 |
| Yang F et al. | Sodium butyrate protects against toxin-induced acute liver failure in rats. | 2014 | HBPD INT | pmid:24919615 |
| Peterson EC and Daugulis AJ | The use of high pressure CO2 -facilitated pH swings to enhance in situ product recovery of butyric acid in a two-phase partitioning bioreactor. | 2014 | Biotechnol. Bioeng. | pmid:24888558 |
| Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
| Lin Y et al. | Use of sodium butyrate as an alternative to dietary fiber: effects on the embryonic development and anti-oxidative capacity of rats. | 2014 | PLoS ONE | pmid:24852604 |
| Pasvolsky R et al. | Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. | 2014 | Int. J. Food Microbiol. | pmid:24801271 |
| Utsugi C et al. | Hard-diet feeding recovers neurogenesis in the subventricular zone and olfactory functions of mice impaired by soft-diet feeding. | 2014 | PLoS ONE | pmid:24817277 |
| Maggio A et al. | Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. | 2014 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:24803033 |
| Ellis JT et al. | Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. | 2014 | Can. J. Microbiol. | pmid:24898684 |
| Milbradt EL et al. | Control of Salmonella Enteritidis in turkeys using organic acids and competitive exclusion product. | 2014 | J. Appl. Microbiol. | pmid:24797347 |
| Ochiai K and Kurita-Ochiai T | [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. | 2014 | Nippon Yakurigaku Zasshi | pmid:25109521 |
| Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
| Liu W et al. | Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. | 2014 | Br. J. Nutr. | pmid:24774835 |
| Saini M et al. | Metabolic engineering of Escherichia coli for production of butyric acid. | 2014 | J. Agric. Food Chem. | pmid:24773075 |
| Ladirat SE et al. | Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. | 2014 | Br. J. Nutr. | pmid:24925303 |
| Liu Y et al. | Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. | 2014 | Biotechnol. Lett. | pmid:24557070 |
| Hu X et al. | Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. | 2014 | Dev. Growth Differ. | pmid:24494796 |
| Singh V et al. | Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia. | 2014 | Neuroscience | pmid:24480366 |
| Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
| Rivkin I et al. | Cancer cell sensitization and improved treatment efficacy by combined sodium butyrate and paclitaxel formulations is cancer-type specific. | 2014 | Int J Pharm | pmid:24370842 |
| Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
| Aoyama Y et al. | Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24345457 |
| Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
| Górka P et al. | Effect of method of delivery of sodium butyrate on maturation of the small intestine in newborn calves. | 2014 | J. Dairy Sci. | pmid:24342681 |
| Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
| Núñez-Jaramillo L et al. | Sodium butyrate into the insular cortex during conditioned taste-aversion acquisition delays aversive taste memory extinction. | 2014 | Neuroreport | pmid:24323127 |
| Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
| Tariq M et al. | Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid. | 2014 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:24322756 |
| Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
| Gagliano H et al. | High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response. | 2014 | Neuropharmacology | pmid:24212060 |
| Tailor D et al. | Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. | 2014 | Mitochondrion | pmid:24177748 |
| Khan S and Jena GB | Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. | 2014 | Chem. Biol. Interact. | pmid:24530320 |
| Peterson AB et al. | Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. | 2014 | Psychopharmacology (Berl.) | pmid:24173624 |
| Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |
| Molina S et al. | Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23973778 |
| Wu Z et al. | Histone deacetylase inhibitors suppress the growth of human osteosarcomas in vitro and in vivo. | 2013 Oct-Dec | J BUON | pmid:24344034 |
| Tigunova EA et al. | [Alternative type of fuel--biobutanol]. | 2013 Nov-Dec | Tsitol. Genet. | pmid:24437198 |
| Misaghi S et al. | Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production. | 2013 May-Jun | Biotechnol. Prog. | pmid:23596153 |
| Jakobsdottir G et al. | Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum. | 2013 | Br. J. Nutr. | pmid:23531375 |
| Balaraman E et al. | Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. | 2013 | Nat Chem | pmid:23344447 |
| Wan S et al. | Anaerobic digestion of municipal solid waste composed of food waste, wastepaper, and plastic in a single-stage system: performance and microbial community structure characterization. | 2013 | Bioresour. Technol. | pmid:23974214 |
| Breidt F et al. | Characterization of cucumber fermentation spoilage bacteria by enrichment culture and 16S rDNA cloning. | 2013 | J. Food Sci. | pmid:23458751 |
| Humphreys KJ et al. | Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. | 2013 | Mol. Carcinog. | pmid:22308110 |
| Yoneda S et al. | Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. | 2013 | Mol Oral Microbiol | pmid:23731652 |
| Rochus K et al. | Highly viscous guar gum shifts dietary amino acids from metabolic use to fermentation substrate in domestic cats. | 2013 | Br. J. Nutr. | pmid:22877608 |
| Cantoni S et al. | Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition. | 2013 | FEBS J. | pmid:23463962 |
| Muhammad A et al. | Novel fluorescent membrane for metronidazole sensing prepared by covalent immobilization of a pyrenebutyric acid derivative. | 2013 | J Fluoresc | pmid:23471624 |
| Tirandaz H and Mohammadi E | Efficient tumor targeting by anaerobic butyrate-producing bacteria. | 2013 | Med. Hypotheses | pmid:23410499 |
| Cuadrado-Tejedor M et al. | Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. | 2013 | Curr. Pharm. Des. | pmid:23448463 |
| Raybuck JD et al. | The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. | 2013 | Pharmacol. Biochem. Behav. | pmid:23454534 |
| Wang HG et al. | Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro. | 2013 | Int. J. Mol. Med. | pmid:23440283 |
| Kedia G et al. | Addressing the challenge of optimum polyhydroxyalkanoate harvesting: monitoring real time process kinetics and biopolymer accumulation using dielectric spectroscopy. | 2013 | Bioresour. Technol. | pmid:23500571 |
| Maliwal BP et al. | Long-lived bright red emitting azaoxa-triangulenium fluorophores. | 2013 | PLoS ONE | pmid:23667570 |
| Arivazhagan G et al. | A probe on the intermolecular forces in diisopropyl ether-n-butyric acid mixture by dielectric, FTIR studies and quantum chemical calculations. | 2013 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:23295216 |
| Cueno ME et al. | Butyric acid retention in gingival tissue induces oxidative stress in jugular blood mitochondria. | 2013 | Cell Stress Chaperones | pmid:23397230 |
| AteÅŸ S et al. | Enhanced ethyl butyrate production using immobilized lipase. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305408 |
| Pappu VK et al. | Butyric acid esterification kinetics over Amberlyst solid acid catalysts: the effect of alcohol carbon chain length. | 2013 | Bioresour. Technol. | pmid:23380294 |
| Sharma P et al. | Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. | 2013 | Arch. Biochem. Biophys. | pmid:23149273 |
| Lim JH et al. | Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. | 2013 | Bioresour. Technol. | pmid:23127832 |
| Zhang Z and Wu WS | Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. | 2013 | Stem Cells Dev. | pmid:23534850 |
| Rawłuszko AA et al. | Reduced expression of steroid sulfatase in primary colorectal cancer. | 2013 | Biomed. Pharmacother. | pmid:23916543 |
| Heinrichs SC et al. | Repeated valproate treatment facilitates fear extinction under specific stimulus conditions. | 2013 | Neurosci. Lett. | pmid:23916657 |
| Sharma B and Sharma PM | Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23921152 |
| Tashiro Y et al. | A novel production process for optically pure L-lactic acid from kitchen refuse using a bacterial consortium at high temperatures. | 2013 | Bioresour. Technol. | pmid:23978480 |
| Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid. | 2013 | Appl. Microbiol. Biotechnol. | pmid:24013291 |
| Stefaniková A et al. | ABT-737 accelerates butyrate-induced death of HL-60 cells. Involvement of mitochondrial apoptosis pathway. | 2013 | Gen. Physiol. Biophys. | pmid:23940089 |
| Hao PP et al. | Isolation of EpCAM(+)/CD133 (-) hepatic progenitor cells. | 2013 | Mol. Cells | pmid:24293012 |
| Venkataramanan KP et al. | The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. | 2013 | BMC Genomics | pmid:24299206 |
| Grousseau E et al. | Impact of sustaining a controlled residual growth on polyhydroxybutyrate yield and production kinetics in Cupriavidus necator. | 2013 | Bioresour. Technol. | pmid:24035890 |
| Cuervo A et al. | Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. | 2013 | Nutr Res | pmid:24074739 |
| Dükkancı M and Gündüz G | Sonolytic degradation of butyric acid in aqueous solutions. | 2013 | J. Environ. Manage. | pmid:24029459 |
| Sánchez-Tena S et al. | Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. | 2013 | Biochim. Biophys. Acta | pmid:23994611 |
| Kim SW et al. | Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. | 2013 | Nucl. Med. Biol. | pmid:23906667 |
| Wei D et al. | Butyric acid production from sugarcane bagasse hydrolysate by Clostridium tyrobutyricum immobilized in a fibrous-bed bioreactor. | 2013 | Bioresour. Technol. | pmid:23270719 |
| Narvaez N et al. | Effects of extracts of Humulus lupulus (hops) and Yucca schidigera applied alone or in combination with monensin on rumen fermentation and microbial populations in vitro. | 2013 | J. Sci. Food Agric. | pmid:23483574 |
| Kumar M et al. | Role of extracellular cues to trigger the metabolic phase shifting from acidogenesis to solventogenesis in Clostridium acetobutylicum. | 2013 | Bioresour. Technol. | pmid:23612162 |
| Jakobsdottir G et al. | Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders. | 2013 | Scand. J. Gastroenterol. | pmid:23600961 |
| Resende WR et al. | Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer. | 2013 | Behav Pharmacol | pmid:23994816 |