butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Hepatoblastoma D018197 10 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Acute Lung Injury D055371 33 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Retinoblastoma D012175 12 associated lipids
Genomic Instability D042822 7 associated lipids
Constipation D003248 8 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Jakobsdottir G et al. Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum. 2013 Br. J. Nutr. pmid:23531375
Balaraman E et al. Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. 2013 Nat Chem pmid:23344447
Wan S et al. Anaerobic digestion of municipal solid waste composed of food waste, wastepaper, and plastic in a single-stage system: performance and microbial community structure characterization. 2013 Bioresour. Technol. pmid:23974214
Humphreys KJ et al. Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 2013 Mol. Carcinog. pmid:22308110
Trokovic R et al. Small molecule inhibitors promote efficient generation of induced pluripotent stem cells from human skeletal myoblasts. 2013 Stem Cells Dev. pmid:22671711
Yoneda S et al. Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. 2013 Mol Oral Microbiol pmid:23731652
Rochus K et al. Highly viscous guar gum shifts dietary amino acids from metabolic use to fermentation substrate in domestic cats. 2013 Br. J. Nutr. pmid:22877608
Cantoni S et al. Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition. 2013 FEBS J. pmid:23463962
Muhammad A et al. Novel fluorescent membrane for metronidazole sensing prepared by covalent immobilization of a pyrenebutyric acid derivative. 2013 J Fluoresc pmid:23471624
Tirandaz H and Mohammadi E Efficient tumor targeting by anaerobic butyrate-producing bacteria. 2013 Med. Hypotheses pmid:23410499
Cuadrado-Tejedor M et al. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. 2013 Curr. Pharm. Des. pmid:23448463
Raybuck JD et al. The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. 2013 Pharmacol. Biochem. Behav. pmid:23454534
Wang HG et al. Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro. 2013 Int. J. Mol. Med. pmid:23440283
Kedia G et al. Addressing the challenge of optimum polyhydroxyalkanoate harvesting: monitoring real time process kinetics and biopolymer accumulation using dielectric spectroscopy. 2013 Bioresour. Technol. pmid:23500571
Fialova B et al. Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines. 2013 Oncol. Rep. pmid:23503510
Ayers LW et al. Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. 2013 Behav. Brain Res. pmid:23831303
Liang X et al. Sodium butyrate protects against severe burn-induced remote acute lung injury in rats. 2013 PLoS ONE pmid:23874764
Wiese BI et al. Short communication: Interrelationship between butyrate and glucose supply on butyrate and glucose oxidation by ruminal epithelial preparations. 2013 J. Dairy Sci. pmid:23810600
Antharam VC et al. Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea. 2013 J. Clin. Microbiol. pmid:23804381
Fujiki R et al. A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons. 2013 Cell Death Dis pmid:23788034
Gałecka M et al. Faecalibacterium prausnitzii and Crohn's disease - is there any connection? 2013 Pol. J. Microbiol. pmid:23829084
Valvassori SS et al. Sodium butyrate reverses the inhibition of Krebs cycle enzymes induced by amphetamine in the rat brain. 2013 J Neural Transm pmid:23851624
St Laurent R et al. Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease. 2013 Neuroscience pmid:23623990
Kidwai F et al. The effects of CD44 down-regulation on stem cell properties of head and neck cancer cell lines. 2013 J. Oral Pathol. Med. pmid:23627635
Contreras AU et al. Deacetylation of p53 induces autophagy by suppressing Bmf expression. 2013 J. Cell Biol. pmid:23629966
Perona M et al. Improvement of the boron neutron capture therapy (BNCT) by the previous administration of the histone deacetylase inhibitor sodium butyrate for the treatment of thyroid carcinoma. 2013 Radiat Environ Biophys pmid:23636505
Maliwal BP et al. Long-lived bright red emitting azaoxa-triangulenium fluorophores. 2013 PLoS ONE pmid:23667570
Arivazhagan G et al. A probe on the intermolecular forces in diisopropyl ether-n-butyric acid mixture by dielectric, FTIR studies and quantum chemical calculations. 2013 Spectrochim Acta A Mol Biomol Spectrosc pmid:23295216
Cueno ME et al. Butyric acid retention in gingival tissue induces oxidative stress in jugular blood mitochondria. 2013 Cell Stress Chaperones pmid:23397230
AteÅŸ S et al. Enhanced ethyl butyrate production using immobilized lipase. 2013 Artif Cells Nanomed Biotechnol pmid:23305408
Pappu VK et al. Butyric acid esterification kinetics over Amberlyst solid acid catalysts: the effect of alcohol carbon chain length. 2013 Bioresour. Technol. pmid:23380294
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Lim JH et al. Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. 2013 Bioresour. Technol. pmid:23127832
Zhang Z and Wu WS Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. 2013 Stem Cells Dev. pmid:23534850
Coskun T et al. Carbodeoxygenation of biomass: the carbonylation of glycerol and higher polyols to monocarboxylic acids. 2013 Chemistry pmid:23536394
Ximenes JC et al. Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. 2013 Naunyn Schmiedebergs Arch. Pharmacol. pmid:23584602
Stojcev Z et al. Early treatment and prevention of the radiation proctitis--composite enemas containing sodium butyrate. 2013 Int J Colorectal Dis pmid:23516076
Nör C et al. The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells. 2013 Mol. Neurobiol. pmid:23516101
Chen HC et al. Preparation of highly conjugated water-dispersible graphene-butyric acid for the enhancement of electron transfer within polyamic acid-benzoxazole: potential applications in electrochemical sensing. 2013 Biosens Bioelectron pmid:23517822
Yaku K et al. AMPK synergizes with the combined treatment of 1'-acetoxychavicol acetate and sodium butyrate to upregulate phase II detoxifying enzyme activities. 2013 Mol Nutr Food Res pmid:23559539
Itzhak Y et al. Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory. 2013 Neurobiol Learn Mem pmid:23567105
Paskova L et al. Different effect of sodium butyrate on cancer and normal prostate cells. 2013 Toxicol In Vitro pmid:23524101
Wang P et al. Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function. 2013 Neurotoxicology pmid:23558232
de Conti A et al. The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway. 2013 Carcinogenesis pmid:23568954
Zhou A et al. Volatile fatty acids productivity by anaerobic co-digesting waste activated sludge and corn straw: effect of feedstock proportion. 2013 J. Biotechnol. pmid:23751505
Mishiro T et al. Butyric acid attenuates intestinal inflammation in murine DSS-induced colitis model via milk fat globule-EGF factor 8. 2013 Lab. Invest. pmid:23752130
Rawłuszko AA et al. Reduced expression of steroid sulfatase in primary colorectal cancer. 2013 Biomed. Pharmacother. pmid:23916543
Heinrichs SC et al. Repeated valproate treatment facilitates fear extinction under specific stimulus conditions. 2013 Neurosci. Lett. pmid:23916657
Sharma B and Sharma PM Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. 2013 Toxicol. Appl. Pharmacol. pmid:23921152
Tashiro Y et al. A novel production process for optically pure L-lactic acid from kitchen refuse using a bacterial consortium at high temperatures. 2013 Bioresour. Technol. pmid:23978480
Jang YS et al. Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid. 2013 Appl. Microbiol. Biotechnol. pmid:24013291
Stefaniková A et al. ABT-737 accelerates butyrate-induced death of HL-60 cells. Involvement of mitochondrial apoptosis pathway. 2013 Gen. Physiol. Biophys. pmid:23940089
Hao PP et al. Isolation of EpCAM(+)/CD133 (-) hepatic progenitor cells. 2013 Mol. Cells pmid:24293012
Venkataramanan KP et al. The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. 2013 BMC Genomics pmid:24299206
Grousseau E et al. Impact of sustaining a controlled residual growth on polyhydroxybutyrate yield and production kinetics in Cupriavidus necator. 2013 Bioresour. Technol. pmid:24035890
Cuervo A et al. Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. 2013 Nutr Res pmid:24074739
Dükkancı M and Gündüz G Sonolytic degradation of butyric acid in aqueous solutions. 2013 J. Environ. Manage. pmid:24029459
Sánchez-Tena S et al. Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. 2013 Biochim. Biophys. Acta pmid:23994611
Damiani R et al. Enhancement of human thyrotropin synthesis by sodium butyrate addition to serum-free CHO cell culture. 2013 Appl. Biochem. Biotechnol. pmid:23996121
Mattace Raso G et al. Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. 2013 PLoS ONE pmid:23861927
Zhang L et al. Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. 2013 PLoS ONE pmid:23861937
Muhammad SI et al. Upregulation of genes related to bone formation by γ-amino butyric acid and γ-oryzanol in germinated brown rice is via the activation of GABAB-receptors and reduction of serum IL-6 in rats. 2013 Clin Interv Aging pmid:24098073
Maioli M et al. Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment. 2013 Drug Des Devel Ther pmid:24101862
Mu D et al. Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. 2013 PLoS ONE pmid:24086397
Li H et al. Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells. 2013 J Biomol Screen pmid:24163393
Cheng J et al. Synthesis and properties of macrocyclic butanoic acid conjugates as a promising delivery formulation for the nutrition of colon. 2013 ScientificWorldJournal pmid:24163636
Kim SW et al. Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. 2013 Nucl. Med. Biol. pmid:23906667
Wei D et al. Butyric acid production from sugarcane bagasse hydrolysate by Clostridium tyrobutyricum immobilized in a fibrous-bed bioreactor. 2013 Bioresour. Technol. pmid:23270719
Kumar M et al. Role of extracellular cues to trigger the metabolic phase shifting from acidogenesis to solventogenesis in Clostridium acetobutylicum. 2013 Bioresour. Technol. pmid:23612162
Jakobsdottir G et al. Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders. 2013 Scand. J. Gastroenterol. pmid:23600961
Xu J et al. Dual role of C/EBPα as an activator and repressor of Gαi2 gene transcription. 2013 Genes Cells pmid:24580717
Resende WR et al. Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer. 2013 Behav Pharmacol pmid:23994816
Franco W and Pérez-Díaz IM Microbial interactions associated with secondary cucumber fermentation. 2013 J. Appl. Microbiol. pmid:23013318
Misaghi S et al. Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production. 2013 May-Jun Biotechnol. Prog. pmid:23596153
Tigunova EA et al. [Alternative type of fuel--biobutanol]. 2013 Nov-Dec Tsitol. Genet. pmid:24437198
Wu Z et al. Histone deacetylase inhibitors suppress the growth of human osteosarcomas in vitro and in vivo. 2013 Oct-Dec J BUON pmid:24344034
Molina S et al. Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. 2013 Oct-Nov Chem. Phys. Lipids pmid:23973778
Unno T et al. Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats. 2014 J. Nutr. Sci. Vitaminol. pmid:25078378
Karki P et al. Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. 2014 Mol. Cell. Biol. pmid:24469401
Pérez-Carro R et al. Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. 2014 Clin. Genet. pmid:23895425
Jin H et al. Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. 2014 J. Biol. Chem. pmid:25342743
Li S et al. High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. 2014 J. Anim. Sci. pmid:25085388
Shin J et al. The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. 2014 J. Biol. Chem. pmid:25037223
Weber TE et al. Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. 2014 J. Anim. Sci. pmid:25023805
Nakata S et al. Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. 2014 Int. J. Oncol. pmid:25017791
Gutiérrez Acosta OB et al. Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. 2014 BMC Genomics pmid:25012398
Ellis JT et al. Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. 2014 Can. J. Microbiol. pmid:24898684
Ochiai K and Kurita-Ochiai T [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. 2014 Nippon Yakurigaku Zasshi pmid:25109521
Liu W et al. Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. 2014 Br. J. Nutr. pmid:24774835
Ladirat SE et al. Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. 2014 Br. J. Nutr. pmid:24925303
Krokowicz L et al. Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis--a prospective randomized study. 2014 Int J Colorectal Dis pmid:24343275
Zhang Z et al. Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. 2014 Cell Reprogram pmid:24568633
Bolhari B et al. Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. 2014 J Endod pmid:24565666
Ai B et al. Butyric acid fermentation of sodium hydroxide pretreated rice straw with undefined mixed culture. 2014 J. Microbiol. Biotechnol. pmid:24561721
Hong JK et al. Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. 2014 Appl. Microbiol. Biotechnol. pmid:24557571
Liu Y et al. Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. 2014 Biotechnol. Lett. pmid:24557070
Hu X et al. Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. 2014 Dev. Growth Differ. pmid:24494796
Ferreira AC et al. Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. 2014 Ann. Hematol. pmid:24577510
Meehan CJ and Beiko RG A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. 2014 Genome Biol Evol pmid:24625961
Pan Y et al. Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. 2014 Technol. Cancer Res. Treat. pmid:23919394