butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

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What functions are associated with butyric acid?


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What lipids are associated with butyric acid?

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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Zhang B et al. Human papillomavirus type 16 E7 protein increases acetylation of histone H3 in human foreskin keratinocytes. 2004 Virology pmid:15476886
Kasumov VT et al. Spectroscopic and electrochemical characterization of di-tert-butylated sterically hindered Schiff bases and their phenoxyl radicals. 2004 Spectrochim Acta A Mol Biomol Spectrosc pmid:15477142
Ichikawa K et al. Heat shock decreases nuclear transport of 3,5,3'-triiodo-L-thyronine in clone 9 cells. 1992 Endocrinology pmid:1547743
Weinberg RS et al. Butyrate increases the efficiency of translation of gamma-globin mRNA. 2005 Blood pmid:15479724
White JB et al. Characterization of 3',5' cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: absence of functional PDE6. 2004 Mol. Vis. pmid:15480303
Liu CA et al. Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis. 2004 Oncogene pmid:15480428
Calabrese V et al. Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. 2004 Arch. Biochem. Biophys. pmid:15488476
Miki K et al. Butyrate suppresses hypoxia-inducible factor-1 activity in intestinal epithelial cells under hypoxic conditions. 2004 Shock pmid:15489637
Sass H and Cypionka H Isolation of sulfate-reducing bacteria from the terrestrial deep subsurface and description of Desulfovibrio cavernae sp. nov. 2004 Syst. Appl. Microbiol. pmid:15490555
Canes D et al. Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo. 2005 Int. J. Cancer pmid:15499627
Hamodeh SA et al. Mechanism of butyrate-induced hyperpolarization of cultured rat myenteric neurones. 2004 Neurogastroenterol. Motil. pmid:15500516
Jolly RA et al. Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. Toxicol Pathol pmid:15503661
Daniel C et al. p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression. 2004 Biochem. Biophys. Res. Commun. pmid:15504345
Mühl H et al. The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells. 2004 Br. J. Pharmacol. pmid:15504750
Cuff MA and Shirazi-Beechey SP The importance of butyrate transport to the regulation of gene expression in the colonic epithelium. 2004 Biochem. Soc. Trans. pmid:15506978
Kis LL et al. In vitro EBV-infected subline of KMH2, derived from Hodgkin lymphoma, expresses only EBNA-1, while CD40 ligand and IL-4 induce LMP-1 but not EBNA-2. 2005 Int. J. Cancer pmid:15514968
Bandyopadhyay D et al. Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway. 2004 Cancer Res. pmid:15520174
Khan KM and Edwards CA In vitro fermentation characteristics of a mixture of Raftilose and guar gum by human faecal bacteria. 2005 Eur J Nutr pmid:15526209
Guzmán-Aránguez A et al. Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5. 2005 J. Cell. Biochem. pmid:15526283
Arvans DL et al. Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15528251
Ramos MG et al. Butyrate increases apoptosis induced by different antineoplastic drugs in monocytic leukemia cells. 2004 Chemotherapy pmid:15528887
Oh YK et al. Thermophilic biohydrogen production from glucose with trickling biofilter. 2004 Biotechnol. Bioeng. pmid:15532039
Turner JE et al. Characterization of Arabidopsis fluoroacetate-resistant mutants reveals the principal mechanism of acetate activation for entry into the glyoxylate cycle. 2005 J. Biol. Chem. pmid:15533942
Awawdeh MS et al. Effects of ammonia load on methionine utilization by growing steers. 2004 J. Anim. Sci. pmid:15537774
Kristensen NB and Harmon DL Effect of increasing ruminal butyrate absorption on splanchnic metabolism of volatile fatty acids absorbed from the washed reticulorumen of steers. 2004 J. Anim. Sci. pmid:15537776
Soto-Navarro SA et al. Effect of fiber-based creep feed on intake, digestion, ruminal fermentation, and microbial efficiency in nursing calves. 2004 J. Anim. Sci. pmid:15537777
Lardy GP et al. Effects of increasing level of supplemental barley on forage intake, digestibility, and ruminal fermentation in steers fed medium-quality grass hay. 2004 J. Anim. Sci. pmid:15537788
Gaudier E et al. Butyrate regulation of glycosylation-related gene expression: evidence for galectin-1 upregulation in human intestinal epithelial goblet cells. 2004 Biochem. Biophys. Res. Commun. pmid:15541394
Sena-Esteves M et al. Optimized large-scale production of high titer lentivirus vector pseudotypes. 2004 J. Virol. Methods pmid:15542136
Manzanilla EG et al. Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs. 2004 J. Anim. Sci. pmid:15542467
Miller SJ Cellular and physiological effects of short-chain fatty acids. 2004 Mini Rev Med Chem pmid:15544545
Marteau P et al. Cellular and physiological effects of probiotics and prebiotics. 2004 Mini Rev Med Chem pmid:15544550
DeFrain JM et al. Feeding glycerol to transition dairy cows: effects on blood metabolites and lactation performance. 2004 J. Dairy Sci. pmid:15545383
Kanso S and Patel BK Phenylobacterium lituiforme sp. nov., a moderately thermophilic bacterium from a subsurface aquifer, and emended description of the genus Phenylobacterium. 2004 Int. J. Syst. Evol. Microbiol. pmid:15545448
Nabandith V et al. Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac. J. Cancer Prev. pmid:15546251
Klehr D et al. Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate. 1992 Biochemistry pmid:1554707
Louis M et al. The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative stress. 2004 Int. J. Oncol. pmid:15547708
Lewis LR and Levine AE Sodium butyrate alters the response of a human colon carcinoma cell line to transforming growth factor-beta 1. 1992 Cancer Lett. pmid:1555205
Fagan P et al. Determination of mono- and di-acylglycerols in milk lipids. 2004 J Chromatogr A pmid:15553151
Li X et al. Butyrate reduces liver metastasis of rat colon carcinoma cells in vivo and resistance to oxidative stress in vitro. 2004 Clin. Exp. Metastasis pmid:15554389
Bennegadi-Laurent N et al. Nutritional and sanitary statuses alter postweaning development of caecal microbial activity in the rabbit. 2004 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:15556384
Sakai M et al. Studies on the conditions required for structural and functional maturation of rabies virus glycoprotein (G) in G cDNA-transfected cells. 2004 Microbiol. Immunol. pmid:15557743
De Vriese C et al. Ghrelin is produced by the human erythroleukemic HEL cell line and involved in an autocrine pathway leading to cell proliferation. 2005 Endocrinology pmid:15564328
Tatara M et al. High-rate thermophilic methane fermentation on short-chain fatty acids in a down-flow anaerobic packed-bed reactor. 2005 Bioprocess Biosyst Eng pmid:15565281
Huang YQ et al. Effects of cell cycle on telomerase activity and on hepatitis B virus replication in HepG2 2.2.15 cells. 2004 HBPD INT pmid:15567742
Kato K et al. Randomized placebo-controlled trial assessing the effect of bifidobacteria-fermented milk on active ulcerative colitis. 2004 Aliment. Pharmacol. Ther. pmid:15569116
Zheng XJ and Yu HQ Inhibitory effects of butyrate on biological hydrogen production with mixed anaerobic cultures. 2005 J. Environ. Manage. pmid:15572082
Daniels T et al. Effects of valproic acid on cardiac metabolism. 2004 Can. J. Physiol. Pharmacol. pmid:15573154
Dhillon VS et al. CpG methylation of the FHIT, FANCF, cyclin-D2, BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian origin. 2004 Mol. Cancer pmid:15574200
Ebert PS et al. Evidence for multiple sites of regulation of heme synthesis in murine erythroleukemia cells. 1979 J. Natl. Cancer Inst. pmid:155751
Kim JS et al. High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. Biotechnol. Prog. pmid:15575713
Decroos K et al. Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions. 2005 Arch. Microbiol. pmid:15578160
Zhang Y and Hamburger AW Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling. 2005 Br. J. Cancer pmid:15583694
Vlaeminck B et al. Rumen odd and branched chain fatty acids in relation to in vitro rumen volatile fatty acid productions and dietary characteristics of incubated substrates. 2004 J Anim Physiol Anim Nutr (Berl) pmid:15584949
Roivainen A et al. Biodistribution and blood metabolism of 1-11C-methyl-4-piperidinyl n-butyrate in humans: an imaging agent for in vivo assessment of butyrylcholinesterase activity with PET. 2004 J. Nucl. Med. pmid:15585478
Wakabayashi K et al. Gene expression associated with the decrease in malignant phenotype of human liver cancer cells following stimulation with a histone deacetylase inhibitor. 2005 Int. J. Oncol. pmid:15586245
Karasawa Y and Okisaka S Inhibition of histone deacetylation by butyrate induces morphological changes in Y79 retinoblastoma cells. 2004 Nov-Dec Jpn. J. Ophthalmol. pmid:15592778
Zduńczyk Z et al. Performance and caecal adaptation of turkeys to diets without or with antibiotic and with different levels of mannan-oligosaccharide. 2004 Arch Anim Nutr pmid:15595620
Juśkiewicz J and Zduńczyk Z Effects of cellulose, carboxymethylcellulose and inulin fed to rats as single supplements or in combinations on their caecal parameters. 2004 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:15596397
Ravizza R et al. Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin. 2004 BMC Cancer pmid:15601469
Zhao Y et al. Histone acetylation regulates both transcription initiation and elongation of hsp22 gene in Drosophila. 2005 Biochem. Biophys. Res. Commun. pmid:15607742
Cho Y et al. An inverse relationship between ceramide synthesis and clinical severity in patients with psoriasis. 2004 J. Korean Med. Sci. pmid:15608398
Bian F et al. Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. 2005 J. Biol. Chem. pmid:15611129
Nafday SM et al. Short-chain fatty acids induce colonic mucosal injury in rats with various postnatal ages. 2005 Pediatr. Res. pmid:15611351
Fu H et al. Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2. 2004 Chin J Dig Dis pmid:15612246
Morioka K et al. Erythroid differentiation and poly(ADP-ribose) synthesis in Friend leukemia cells. 1979 Gan pmid:156137
Kim JD and Kang KH Isolation of Lactobacillus sakei strain KJ-2008 and its removal of characteristic malodorous gases under anaerobic culture conditions. 2004 Biosci. Biotechnol. Biochem. pmid:15618611
Wang P et al. [Sodium butyrate induces rat hepatic oval cells differentiating into mature hepatocytes in vitro]. 2004 Zhonghua Gan Zang Bing Za Zhi pmid:15619336
Lee JY et al. Thiobutacin, a novel antifungal and antioomycete antibiotic from Lechevalieria aerocolonigenes. 2004 J. Nat. Prod. pmid:15620255
Rahmani M et al. Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change. 2005 Mol. Pharmacol. pmid:15625278
Hirshfield S et al. Crystal methamphetamine use predicts incident STD infection among men who have sex with men recruited online: a nested case-control study. 2004 J. Med. Internet Res. pmid:15631965
Shivshankar P and Devi SC Screening of stimulatory effects of dietary risk factors on mouse intestinal cell kinetics. 2005 World J. Gastroenterol. pmid:15633224
Bordin M et al. Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. 2004 Mol. Cancer Res. pmid:15634758
Machavaram KK et al. Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats. 2004 Pharmazie pmid:15638086
Jagielski AK et al. The role of intracellular cAMP in renal gluconeogenesis in view of differential action of various cAMP analogues. 2005 Arch. Biochem. Biophys. pmid:15639228
Monneret C Histone deacetylase inhibitors. 2005 Eur J Med Chem pmid:15642405
Sezik E et al. Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay-directed fractionation techniques. 2005 Life Sci. pmid:15642593
Hristov AN et al. Effect of carbohydrate source on ammonia utilization in lactating dairy cows. 2005 J. Anim. Sci. pmid:15644514
Kuroda J et al. Promotion of cell differentiation, and suppression of cell growth and cyclooxygenase-2 expression by differentiation-inducing agents in human oral squamous carcinoma SCC25 cells. 2005 Int. J. Oncol. pmid:15645120
Looby E et al. Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner. 2005 Int. J. Cancer pmid:15645414
Hiesberger T et al. Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis. 2005 J. Biol. Chem. pmid:15647252
Turecková J et al. Sodium butyrate-mediated differentiation of colorectal cancer cells: regulation of PKCbetaII by PI 3-kinase. 2005 Int. J. Mol. Med. pmid:15647851
Hossain Z et al. Effect of polyunsaturated fatty acid-enriched phosphatidylcholine and phosphatidylserine on butyrate-induced growth inhibition, differentiation and apoptosis in Caco-2 cells. 2006 Mar-Apr Cell Biochem. Funct. pmid:15648055
Zlotnik Y et al. Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay. 2005 Br. J. Cancer pmid:15655545
Hanafusa T et al. Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation. 2005 BMC Cancer pmid:15661074
Aulenta F et al. Assessment of natural or enhanced in situ bioremediation at a chlorinated solvent-contaminated aquifer in Italy: a microcosm study. 2005 Environ Int pmid:15661281
Rozental R et al. Sodium butyrate induces apoptosis in MSN neuroblastoma cells in a calcium independent pathway. 2004 Neurochem. Res. pmid:15662847
Küçük A et al. Investigation of the pharmacokinetics and determination of tramadol in rabbit plasma by a high-performance liquid chromatography-diode array detector method using liquid-liquid extraction. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15664351
Ganapathy V et al. Biological functions of SLC5A8, a candidate tumour suppressor. 2005 Biochem. Soc. Trans. pmid:15667316
Mustafa T et al. Expression of the epidermal growth factor seven-transmembrane member CD97 correlates with grading and staging in human oral squamous cell carcinomas. 2005 Cancer Epidemiol. Biomarkers Prev. pmid:15668483
Vidyasagar S et al. Role of short-chain fatty acids in colonic HCO(3) secretion. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15677553
Peng H et al. Label-free electrochemical DNA sensor based on functionalised conducting copolymer. 2005 Biosens Bioelectron pmid:15681199
Roediger WE Oxidative and synthetic functions of n-Butyrate in colonocytes. 1992 Dis. Colon Rectum pmid:1568404
Ramsay RG et al. Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS. 2005 DNA Cell Biol. pmid:15684716
Hague A et al. Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis. 2005 Br. J. Cancer pmid:15685228
Alkharfy KM et al. Liquid chromatographic assay of abouthiouzine in plasma and its application to pharmacokinetic studies. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15686983
Lykke-Andersen J and Wagner E Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. 2005 Genes Dev. pmid:15687258
Joseph J et al. Role of p53 status in chemosensitivity determination of cancer cells against histone deacetylase inhibitor sodium butyrate. 2005 Int. J. Cancer pmid:15688418
Hadjiagapiou C et al. Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate transporter 1 promoter. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15691871
Collins JF et al. c-myc antisense oligonucleotides inhibit the colony-forming capacity of Colo 320 colonic carcinoma cells. 1992 J. Clin. Invest. pmid:1569190