butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Diverticulitis D004238 1 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Strongylida Infections D017206 5 associated lipids
Marek Disease D008380 4 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Facial Injuries D005151 1 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Nose Neoplasms D009669 3 associated lipids
Pouchitis D019449 3 associated lipids
Teratocarcinoma D018243 7 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Early JV et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. 2016 Antimicrob. Agents Chemother. pmid:27044545
Hoberg KA et al. Inhibitory effect of cerulenin and sodium butyrate on germination of Candida albicans. 1983 Antimicrob. Agents Chemother. pmid:6357077
Rocchi P et al. Growth inhibitory and differentiating effects of sodium butyrate on human neuroblastoma cells in culture. 1992 May-Jun Anticancer Res. pmid:1622149
Kyritsis AP et al. Control of retinoblastoma cell growth by differentiating agents: current work and future directions. 1986 May-Jun Anticancer Res. pmid:2427007
Lea MA and Randolph VM Induction of reporter gene expression by inhibitors of histone deacetylase. 1998 Jul-Aug Anticancer Res. pmid:9703934
Sarkar S et al. Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling. 2011 Anticancer Res. pmid:21868513
Lee IS et al. Suppressive effects of Adenophora triphylla extracts on in vitro tumor cell growth and in vivo gastric epithelial proliferation. 2000 Sep-Oct Anticancer Res. pmid:11062747
Yoshida M et al. Effect of hexafluoro-1,25-dihydroxyvitamin D3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells. 1992 Nov-Dec Anticancer Res. pmid:1363510
Kim J et al. Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. Anticancer Res. pmid:17970072
Tsai LC et al. Apoptosis induced by the sodium butyrate in human gastric cancer TMK-1 cells. 2000 Jul-Aug Anticancer Res. pmid:10953308
Gabius S et al. Regulation of distribution, amount and ligand affinity of sugar receptors in human colon carcinoma cells by treatment with sodium butyrate, retinoic acid and phorbol ester. 1990 Jul-Aug Anticancer Res. pmid:2382971
Decrion-Barthod AZ et al. Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells. 2010 Anticancer Res. pmid:21036719
Durdux M et al. Fluorescence-based assessment of LRP activity: a comparative study. Anticancer Res. pmid:15161018
Lea MA et al. Inhibition of growth and induction of differentiation of colon cancer cells by peach and plum phenolic compounds. 2008 Jul-Aug Anticancer Res. pmid:18751377
Louache F et al. Characterization of phorbol esters binding to K 562 cells. 1984 Jan-Apr Anticancer Res. pmid:6324650
Singh NP and Lai HC Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. Anticancer Res. pmid:16309236
Boulikas T Poly(ADP-ribose) synthesis in blocked and damaged cells and its relation to carcinogenesis. 1992 May-Jun Anticancer Res. pmid:1535771
Lacroix J et al. In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. 1988 Jul-Aug Anticancer Res. pmid:3052247
Kuwajima A et al. The histone deacetylase inhibitor butyrate inhibits melanoma cell invasion of Matrigel. 2007 Nov-Dec Anticancer Res. pmid:18225587
Lea MA et al. Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. Anticancer Res. pmid:17465197
Miki Y et al. Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. Anticancer Res. pmid:17595767
Ramp U et al. Differentiation induction in the human rhabdomyosarcoma cell line TE-671. A morphological, biochemical and molecular analysis. 1995 Jan-Feb Anticancer Res. pmid:7733631
Pellizzaro C et al. Cholesteryl butyrate in solid lipid nanospheres as an alternative approach for butyric acid delivery. 1999 Sep-Oct Anticancer Res. pmid:10628332
Wei ZL et al. Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. Anticancer Res. pmid:18630528
Katzenmaier EM et al. Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro. 2014 Anticancer Res. pmid:25275038
Wang XM et al. Inhibition of proliferation, invasion and adhesion of liver cancer cells by 5-azacytidine and butyrate. 1999 Jul-Aug Anticancer Res. pmid:10652571
Gladhaug IP et al. Regulation of hepatocyte epidermal growth factor receptors by n-butyrate and dimethyl sulfoxide: sensitivity to modulation by the tumor promoter TPA. 1989 Nov-Dec Anticancer Res. pmid:2627113
Lea MA et al. Addition of 2-deoxyglucose enhances growth inhibition but reverses acidification in colon cancer cells treated with phenformin. 2011 Anticancer Res. pmid:21378320
Litvak DA et al. Induction of apoptosis in human gastric cancer by sodium butyrate. 2000 Mar-Apr Anticancer Res. pmid:10810354
Lea MA et al. Inhibition of growth and induction of differentiation markers by polyphenolic molecules and histone deacetylase inhibitors in colon cancer cells. 2010 Anticancer Res. pmid:20332434
Yamamura T et al. Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. 2014 Anticancer Res. pmid:24692699
Petit JM et al. mdr 1 gene-expression and villin synthesis in a colon cancer cell line differentiated by sodium butyrate. 1993 Mar-Apr Anticancer Res. pmid:8517666
Lea MA et al. Butyramide and monobutyrin: growth inhibitory and differentiating agents. 1993 Jan-Feb Anticancer Res. pmid:8476205
Kato K Endometrial cancer stem cells: a new target for cancer therapy. 2012 Anticancer Res. pmid:22641664
Sjöholm A Sodium butyrate inhibits rat insulinoma cell proliferation without affecting the cellular insulin content or insulin release. 1993 Anticancer Drugs pmid:8490204
Fagot D et al. Antiproliferative effects of sodium butyrate in adriamycin-sensitive and -resistant human cancer cell lines. 1994 Anticancer Drugs pmid:7858287
Massart C et al. Effect of all-trans retinoic acid and sodium butyrate in vitro and in vivo on thyroid carcinoma xenografts. 2006 Anticancer Drugs pmid:16702813
Serpe L et al. Cholesteryl butyrate solid lipid nanoparticles as a butyric acid pro-drug: effects on cell proliferation, cell-cycle distribution and c-myc expression in human leukemic cells. 2004 Anticancer Drugs pmid:15166628
Dong QG et al. Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. 1993 Anticancer Drugs pmid:8298162
Gonçalves P et al. The effect of clotrimazole on energy substrate uptake and carcinogenesis in intestinal epithelial cells. 2012 Anticancer Drugs pmid:22075978
Massart C et al. Effect of sodium butyrate on doxorubicin resistance and expression of multidrug resistance genes in thyroid carcinoma cells. 2005 Anticancer Drugs pmid:15711177
Tolstykh IV et al. [Extraction of rifamycin B from native and aqueous solutions]. 1975 Antibiotiki pmid:237467
Vatin AE and Filatov PP [Pharmacokinetics of C14-olivomycin in the body of mice with lymphosarcoma (L10-1 strain)]. 1975 Antibiotiki pmid:1173211
Tukey RH and Strassburg CP Human UDP-glucuronosyltransferases: metabolism, expression, and disease. 2000 Annu. Rev. Pharmacol. Toxicol. pmid:10836148
Sanderson IR and Naik S Dietary regulation of intestinal gene expression. 2000 Annu. Rev. Nutr. pmid:10940337
Haraguchi N et al. CD133+CD44+ population efficiently enriches colon cancer initiating cells. 2008 Ann. Surg. Oncol. pmid:18663533
Wang XM et al. Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. 1998 Ann. Surg. pmid:9637556
Nguyen KA et al. Dietary fiber enhances a tumor suppressor signaling pathway in the gut. 2006 Ann. Surg. pmid:16632996
Bode BP and Souba WW Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. 1994 Ann. Surg. pmid:7944654
Khan MZ et al. Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. 1993 Ann. Oncol. pmid:8394737