butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Diverticulitis D004238 1 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Strongylida Infections D017206 5 associated lipids
Marek Disease D008380 4 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Facial Injuries D005151 1 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Nose Neoplasms D009669 3 associated lipids
Pouchitis D019449 3 associated lipids
Teratocarcinoma D018243 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Pinto JT et al. Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds. 2011 Amino Acids pmid:20383543
Andrews FM et al. In vitro effects of hydrochloric acid and various concentrations of acetic, propionic, butyric, or valeric acids on bioelectric properties of equine gastric squamous mucosa. 2006 Am. J. Vet. Res. pmid:17078749
Minder HP et al. In vitro fermentation of feces from normal and chronically diarrheal horses. 1980 Am. J. Vet. Res. pmid:6447466
Allemann M et al. Effect of sodium butyric acid, sodium valerianic acid, and osmolarity on contractility of specimens of intestinal wall obtained from the cecum and spiral colon of healthy cows. 2000 Am. J. Vet. Res. pmid:10850845
Targowski SP and Klucinski W Reduction in mitogenic response of bovine lymphocytes by ketone bodies. 1983 Am. J. Vet. Res. pmid:6603180
Mills SW et al. Evaluation of the effects of short-chain fatty acids and extracellular pH on bovine neutrophil function in vitro. 2006 Am. J. Vet. Res. pmid:17078753
Cao XX et al. Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. 2001 Am. J. Respir. Cell Mol. Biol. pmid:11713097
Gill RK and Dudeja PK A novel facet to consider for the effects of butyrate on its target cells. Focus on "The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein". 2011 Am. J. Physiol., Cell Physiol. pmid:21832244
Gonçalves P et al. The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein. 2011 Am. J. Physiol., Cell Physiol. pmid:21775706
Lam P et al. Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases. 2007 Am. J. Physiol., Cell Physiol. pmid:17855769
Loffing-Cueni D et al. Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. 2001 Am. J. Physiol., Cell Physiol. pmid:11698247
Nakhoul NL et al. pH sensitivity of ammonium transport by Rhbg. 2010 Am. J. Physiol., Cell Physiol. pmid:20810915
Cooper GJ and Fong P Relationship between intracellular pH and chloride in Xenopus oocytes expressing the chloride channel ClC-0. 2003 Am. J. Physiol., Cell Physiol. pmid:12388074
Said HM et al. Mechanism of nicotinic acid transport in human liver cells: experiments with HepG2 cells and primary hepatocytes. 2007 Am. J. Physiol., Cell Physiol. pmid:17928533
Kiela PR et al. Molecular mechanism of rat NHE3 gene promoter regulation by sodium butyrate. 2007 Am. J. Physiol., Cell Physiol. pmid:17344314
Krishnan S et al. Apical NHE isoforms differentially regulate butyrate-stimulated Na absorption in rat distal colon. 2003 Am. J. Physiol., Cell Physiol. pmid:12878493
Resta-Lenert S et al. Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. 2001 Am. J. Physiol., Cell Physiol. pmid:11698242
Zhao L et al. ¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. 2011 Am. J. Physiol. Renal Physiol. pmid:21228107
Nakhoul NL et al. Ammonium interaction with the epithelial sodium channel. 2001 Am. J. Physiol. Renal Physiol. pmid:11502598
Laughery MD et al. Selective basolateral localization of overexpressed Na-K-ATPase beta1- and beta2- subunits is disrupted by butryate treatment of MDCK cells. 2007 Am. J. Physiol. Renal Physiol. pmid:17344187
Kumar P et al. Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. 2017 Am. J. Physiol. Renal Physiol. pmid:28566502
Brown AC et al. RhCG is the major putative ammonia transporter expressed in the human kidney, and RhBG is not expressed at detectable levels. 2009 Am. J. Physiol. Renal Physiol. pmid:19357182
Leipziger J et al. PKA site mutations of ROMK2 channels shift the pH dependence to more alkaline values. 2000 Am. J. Physiol. Renal Physiol. pmid:11053053
Park GY et al. Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. 2004 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:14672923
Bao JX et al. Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries. 2010 Am. J. Physiol. Heart Circ. Physiol. pmid:20061541
Ochiai K et al. Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557577
Rexhaj E et al. Fetal programming of pulmonary vascular dysfunction in mice: role of epigenetic mechanisms. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21536851
Arvans DL et al. Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15528251
Musch MW et al. SCFA increase intestinal Na absorption by induction of NHE3 in rat colon and human intestinal C2/bbe cells. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11254495
Shie JL et al. Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11005769
Suply E et al. Butyrate enemas enhance both cholinergic and nitrergic phenotype of myenteric neurons and neuromuscular transmission in newborn rat colon. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22492692
Lal S et al. Vagal afferent responses to fatty acids of different chain length in the rat. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11557510
Subramanya SB et al. Differential regulation of cholera toxin-inhibited Na-H exchange isoforms by butyrate in rat ileum. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17690171
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Kumar A et al. Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26272259
Amin MR et al. Involvement of Sp1 and Sp3 in differential regulation of human NHE3 promoter activity by sodium butyrate and IFN-gamma/TNF-alpha. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17540780
Xu H et al. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26159698
Parhar K et al. Short-chain fatty acid mediated phosphorylation of heat shock protein 25: effects on camptothecin-induced apoptosis. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16469826
Marcil V et al. Modulation of lipid synthesis, apolipoprotein biogenesis, and lipoprotein assembly by butyrate. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12121881
Borthakur A et al. Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 level. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16150873
Srinivas SR et al. Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17855766
Cuche G et al. Desensitization of ileal vagal receptors by short-chain fatty acids in pigs. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11292611
Cao Y et al. Dietary fiber enhances TGF-β signaling and growth inhibition in the gut. 2011 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21454444
Alrefai WA et al. Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14525727
Gaudier E et al. Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15308471
Grider JR and Piland BE The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16973914
Pawelka AJ and Huizinga JD Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25540235
Hadjiagapiou C et al. Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate transporter 1 promoter. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15691871
Yuan L et al. Schlafen 3 induction by cyclic strain regulates intestinal epithelial differentiation. 2010 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20299602
Sonoyama K et al. Upregulation of activin A gene by butyrate in human colon cancer cell lines. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12540370