| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kassis S | Modulation of the receptor-coupled adenylate cyclase system in HeLa cells by sodium butyrate. | 1985 | Biochemistry | pmid:3000434 |
| Perry CA et al. | Analysis of nucleosome assembly and histone exchange using antibodies specific for acetylated H4. | 1993 | Biochemistry | pmid:7504954 |
| Honda J et al. | Spectroscopic observation of the intramolecular electron transfer in the photoactivation processes of nitrile hydratase. | 1994 | Biochemistry | pmid:8142355 |
| Perry CA et al. | Parental nucleosomes segregated to newly replicated chromatin are underacetylated relative to those assembled de novo. | 1993 | Biochemistry | pmid:8257695 |
| Yamada H and O'Leary MH | Stereochemistry of reactions catalyzed by glutamate decarboxylase. | 1978 | Biochemistry | pmid:341973 |
| Cross TA et al. | Ketogenesis in the living rat followed by 13C NMR spectroscopy. | 1984 | Biochemistry | pmid:6529555 |
| Kennedy J et al. | 6-Deoxyerythronolide B analogue production in Escherichia coli through metabolic pathway engineering. | 2003 | Biochemistry | pmid:14640703 |
| Murphy LD et al. | Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression. | 1990 | Biochemistry | pmid:1979752 |
| Reczek PR et al. | Sodium butyrate induced structural changes in HeLa cell chromatin. | 1982 | Biochemistry | pmid:7074068 |
| Chen H et al. | Characterization of two promoters of a rat pregnancy-specific glycoprotein gene. | 1994 | Biochemistry | pmid:8068638 |
| Ausio J and van Holde KE | Histone hyperacetylation: its effects on nucleosome conformation and stability. | 1986 | Biochemistry | pmid:3964683 |
| D'Anna JA et al. | Histones H1(o)a and H1(o)b are the same as CHO histones H1(III) and H1(IV): new features of H1(o) phosphorylation during the cell cycle. | 1981 | Biochemistry | pmid:7284339 |
| Cox GS | Synthesis of the glycoprotein hormone alpha subunit and placental alkaline phosphatase by HeLa cells: effect of tunicamycin, 2-deoxyglucose, and sodium butyrate. | 1981 | Biochemistry | pmid:7295657 |
| Gambari R et al. | Human leukemic K562 cells: suppression of hemoglobin accumulation by a monoclonal antibody to human transferrin receptor. | 1986 | Biochim. Biophys. Acta | pmid:3008852 |
| Marshall MO and Knudsen J | Factors influencing the in vitro activity of diacylglycerol acyltransferase from bovine mammary gland and liver towards butyryl-CoA and palmitoyl-CoA. | 1980 | Biochim. Biophys. Acta | pmid:7370285 |
| Hopkins D and Manchester KL | Cyclic nucleotides in the denervated rat diaphragm and the effect of cyclic AMP on ornithine and adenosylmethionine decarboxylases. | 1981 | Biochim. Biophys. Acta | pmid:6274418 |
| Kaptein A et al. | Butyrate stimulates the secretion of apolipoprotein B-100-containing lipoproteins from HepG2 cells by inhibiting the intracellular degradation. | 1994 | Biochim. Biophys. Acta | pmid:8049249 |
| Brass EP and Garrity MJ | Modulation of prostaglandin E2 catabolism and action by fuel substrates in rat hepatocytes. | 1989 | Biochim. Biophys. Acta | pmid:2912505 |
| Alonso WR and Nelson DA | A novel yeast histone deacetylase: partial characterization and development of an activity assay. | 1986 | Biochim. Biophys. Acta | pmid:3513841 |
| Tamura RN and Cox GS | Effect of pyrimidine deoxynucleosides and sodium butyrate on expression of the glycoprotein hormone alpha-subunit and placental alkaline phosphatase in HeLa cells. | 1988 | Biochim. Biophys. Acta | pmid:2449248 |
| Golzio M et al. | Cell synchronization effect on mammalian cell permeabilization and gene delivery by electric field. | 2002 | Biochim. Biophys. Acta | pmid:12007621 |
| Bombik BM and Baserga R | Effect of cyclic AMP on chromatin-bound protein kinases in WI-38 fibroblasts stimulated to proliferate. | 1976 | Biochim. Biophys. Acta | pmid:183819 |
| Spiegel S | Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin. | 1988 | Biochim. Biophys. Acta | pmid:2835987 |
| Papazafiri P et al. | Expression of muscle calsequestrin in epithelial HeLa cells: distribution and functional role. | 1994 | Biochim. Biophys. Acta | pmid:7918667 |
| Pellegrini S et al. | A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization of its product. | 2002 | Biochim. Biophys. Acta | pmid:11997086 |
| Koshihara Y et al. | Induction of prostacyclin formation by sodium n-butyrate in a cloned epithelial liver cell line. | 1981 | Biochim. Biophys. Acta | pmid:6788091 |
| Herz F and Halwer M | Preferential alkaline phosphatase isoenzyme induction by sodium butyrate. | 1983 | Biochim. Biophys. Acta | pmid:6830876 |
| Tallman JF et al. | Properties of beta-adrenergic receptors in untreated and butyrate-treated Hela cells. | 1978 | Biochim. Biophys. Acta | pmid:208639 |
| Waterborg JH et al. | Dynamic histone acetylation in alfalfa cells. Butyrate interference with acetate labeling. | 1990 | Biochim. Biophys. Acta | pmid:2383588 |
| Nègre A et al. | Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. | 1987 | Biochim. Biophys. Acta | pmid:3030438 |
| Jasinskas A et al. | Turnover of histone acetyl groups during sea urchin early development is not required for histone, heat shock and actin gene transcription. | 1997 | Biochim. Biophys. Acta | pmid:9116030 |
| Ranney MK et al. | Multiple pathways regulating the anti-apoptotic protein clusterin in breast cancer. | 2007 | Biochim. Biophys. Acta | pmid:17689225 |
| Nakamura N et al. | Changes in the cellular glycosaminoglycans of cultured mastocytoma cells induced by sodium butyrate. | 1980 | Biochim. Biophys. Acta | pmid:6766327 |
| Böhm L et al. | Influence of histone acetylation on the modification of cytoplasmic and nuclear proteins by ADP-ribosylation in response to free radicals. | 1997 | Biochim. Biophys. Acta | pmid:9101708 |
| Emre N et al. | Analysis of MVP and VPARP promoters indicates a role for chromatin remodeling in the regulation of MVP. | 2004 | Biochim. Biophys. Acta | pmid:15093136 |
| Koshihara Y et al. | Sodium n-butyrate induces prostaglandin synthetase activity in mastocytoma P-815 cells. | 1980 | Biochim. Biophys. Acta | pmid:6768397 |
| Barrasa JI et al. | Histone deacetylase inhibitors upregulate MMP11 gene expression through Sp1/Smad complexes in human colon adenocarcinoma cells. | 2012 | Biochim. Biophys. Acta | pmid:22227581 |
| Daubeuf S et al. | Differential regulation of gamma-glutamyltransferase mRNAs in four human tumour cell lines. | 2001 | Biochim. Biophys. Acta | pmid:11731087 |
| Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
| Birckbichler PJ et al. | Enhanced transglutaminase activity in transformed human lung fibroblast cells after exposure to sodium butyrate. | 1983 | Biochim. Biophys. Acta | pmid:6135451 |
| Halestrap AP et al. | The role of mitochondria in protection of the heart by preconditioning. | 2007 | Biochim. Biophys. Acta | pmid:17631856 |
| Granitzer M and Steels P | Role of Na+/K+ exchange and organic acids in base induced hyperpolarization of renal proximal amphibian tubule. | 1991 | Biochim. Biophys. Acta | pmid:1648393 |
| Herz F | Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. | 1993 | Biochim. Biophys. Acta | pmid:8422435 |
| Imada M et al. | Induction of surface glycoprotein expression by cyclic AMP in Chinese hamster ovary cells. | 1980 | Biochim. Biophys. Acta | pmid:6251908 |
| Giardina C and Inan MS | Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells. | 1998 | Biochim. Biophys. Acta | pmid:9540818 |
| Gonnella R et al. | PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. | 2015 | Biochim. Biophys. Acta | pmid:25827954 |
| Wijcik L et al. | Induction of alkaline phosphatase in cultured human fibroblasts. Comparison of normal cells and those from patients with cystic fibrosis. | 1979 | Biochim. Biophys. Acta | pmid:486538 |
| Vanecková I et al. | Intracellular pH regulation in colonocytes of rat proximal colon. | 2001 | Biochim. Biophys. Acta | pmid:11406345 |
| Dafforn A et al. | Aliphatic ketones are acetylcholinesterase inhibitors but not transition state analogs. | 1979 | Biochim. Biophys. Acta | pmid:465505 |
| Johnston RW et al. | Associative properties of butyryl-coenzyme A synthetase from ox liver mitochondria. | 1979 | Biochim. Biophys. Acta | pmid:465508 |
| Dayal V et al. | Cyclic AMP induces synthesis of prostaglandin E1 in platelets. | 1983 | Biochim. Biophys. Acta | pmid:6309248 |
| Warren L | Sialic acid lyase in human promyelocytic leukemic cells (HL-60) during phorbol-ester-induced differentiation. | 1986 | Biochim. Biophys. Acta | pmid:3463364 |
| Itoh N et al. | Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. | 2001 | Biochim. Biophys. Acta | pmid:11342031 |
| Tanaka K et al. | Enhanced expression of mRNAs of antisecretory factor-1, gp96, DAD1 and CDC34 in human hepatocellular carcinomas. | 2001 | Biochim. Biophys. Acta | pmid:11335099 |
| Nonaka T et al. | Effect of cyclic AMP on urokinase-type plasminogen activator receptor and fibrinolytic factors in a human osteoblast-like cell line. | 1995 | Biochim. Biophys. Acta | pmid:7718621 |
| Natoni F et al. | Sodium butyrate sensitises human pancreatic cancer cells to both the intrinsic and the extrinsic apoptotic pathways. | 2005 | Biochim. Biophys. Acta | pmid:16109447 |
| Cosgrove DE and Cox GS | Effects of sodium butyrate and 5-azacytidine on DNA methylation in human tumor cell lines: variable response to drug treatment and withdrawal. | 1990 | Biochim. Biophys. Acta | pmid:1698097 |
| Martin RL et al. | Characterisation of putrescine uptake by cultured adult mouse hepatocytes. | 1990 | Biochim. Biophys. Acta | pmid:2297540 |
| Müllner E et al. | Increased levels of dihydrofolate reductase mRNA can be measured in normal, growth-stimulated mouse fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6688360 |
| Herz F and Halwer M | Modulation of alkaline phosphatases in LoVo, a human colon carcinoma cell line. | 1989 | Biochim. Biophys. Acta | pmid:2804087 |
| Kato T et al. | Short- and medium-chain fatty acids enhance the cell surface expression and transport capacity of the bile salt export pump (BSEP/ABCB11). | 2010 | Biochim. Biophys. Acta | pmid:20398791 |
| Jørgensen KE and Sheikh MI | Characteristics of uptake of short chain fatty acids by luminal membrane vesicles from rabbit kidney. | 1986 | Biochim. Biophys. Acta | pmid:3741867 |
| Reboulleau CP et al. | Maintenance of DNA integrity during murine erythroleukemia cell differentiation induced by ethionine and other hypomethylation agents. | 1983 | Biochim. Biophys. Acta | pmid:6574790 |
| Sugden MC and Watts DI | Effects of L-alanine on ketogenesis in vitro. | 1982 | Biochim. Biophys. Acta | pmid:7115774 |
| Shuttleworth J et al. | Protein synthesis in human lymphoblastoid cells (Namalwa) after treatment with butyrate and 5'-bromodeoxyuridine. | 1982 | Biochim. Biophys. Acta | pmid:6288100 |
| Hance AJ et al. | Hyperoxic-induced alterations in lung cell structure and function. Effects on cellular cyclic AMP content and comparison to alterations produced by exogenous cyclic AMP. | 1982 | Biochim. Biophys. Acta | pmid:6288116 |
| Barrasa JI et al. | Resistance to butyrate impairs bile acid-induced apoptosis in human colon adenocarcinoma cells via up-regulation of Bcl-2 and inactivation of Bax. | 2012 | Biochim. Biophys. Acta | pmid:22917577 |
| Jiakuntorn Y and Mathias AP | The effect of sodium butyrate on acetylation in vitro of chromosomal proteins in three classes of liver nuclei from different ages of rats. | 1982 | Biochim. Biophys. Acta | pmid:7126585 |
| Sánchez-Tena S et al. | Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. | 2013 | Biochim. Biophys. Acta | pmid:23994611 |
| Pettersen I et al. | Heterogeneity in gamma-glutamyltransferase mRNA expression and glycan structures. Search for tumor-specific variants in human liver metastases and colon carcinoma cells. | 2003 | Biochim. Biophys. Acta | pmid:12758164 |
| Povinelli CM et al. | Differential and coordinate responses of the human genes encoding the heat stable alkaline phosphatases to cAMP and sodium butyrate in the choriocarcinoma line JEG-3. | 1992 | Biochim. Biophys. Acta | pmid:1739739 |
| Herz F and Halwer M | Synergistic induction of alkaline phosphatase in colonic carcinoma cells by sodium butyrate and hyperosmolality. | 1982 | Biochim. Biophys. Acta | pmid:7138912 |
| Leschelle X et al. | Adaptative metabolic response of human colonic epithelial cells to the adverse effects of the luminal compound sulfide. | 2005 | Biochim. Biophys. Acta | pmid:15996823 |
| Kaiho S and Mizuno K | Inhibition of Friend cell erythrodifferentiation by modification of membrane phospholipid composition by choline analogues. | 1985 | Biochim. Biophys. Acta | pmid:3855361 |
| Nicolay K et al. | Carbon-13 nuclear magnetic resonance studies of acetate metabolism in intact cells of rhodopseudomonas sphaeroides. | 1982 | Biochim. Biophys. Acta | pmid:6980672 |
| Bidet M et al. | Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. | 1988 | Biochim. Biophys. Acta | pmid:3342236 |
| Matsuki H et al. | Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate. | 1999 | Biochim. Biophys. Acta | pmid:9878713 |
| Waterborg JH | Plant histone acetylation: in the beginning ... | 2011 | Biochim. Biophys. Acta | pmid:21371578 |
| Lee KN et al. | Induction of cellular transglutaminase biosynthesis by sodium butyrate. | 1987 | Biochim. Biophys. Acta | pmid:2881581 |
| Park YJ et al. | A novel dienelactone hydrolase from the thermoacidophilic archaeon Sulfolobus solfataricus P1: purification, characterization, and expression. | 2010 | Biochim. Biophys. Acta | pmid:20655986 |
| Kucera I | Energy coupling to nitrate uptake into the denitrifying cells of Paracoccus denitrificans. | 2005 | Biochim. Biophys. Acta | pmid:16112075 |
| Belakavadi M et al. | Purification and characterization of butyrate-induced protein phosphatase involved in apoptosis of Ehrlich ascites tumor cells. | 2007 | Biochim. Biophys. Acta | pmid:17029793 |
| Sasi R and Fasman GD | The effect of a high mobility group protein (HMG 17) on the structure of acetylated and control core HeLa cell chromatin. | 1984 | Biochim. Biophys. Acta | pmid:6232953 |
| Voigt J et al. | Absence of hydrocortisone from cytoplasmic hormone-protein complexes formed in vivo after administration of biologically active doses of [3H]hydrocortisone. | 1981 | Biochim. Biophys. Acta | pmid:7236733 |
| Friedrichs D | On the stimulation of gluconeogenesis by L-lysine in isolated rat kidney cortex tubules. | 1975 | Biochim. Biophys. Acta | pmid:1131363 |
| Ueda M et al. | Up-regulation of the peroxisomal beta-oxidation system occurs in butyrate-grown Candida tropicalis following disruption of the gene encoding peroxisomal 3-ketoacyl-CoA thiolase. | 2003 | Biochim. Biophys. Acta | pmid:12633682 |
| Sorimachi K et al. | Inhibitory effect of dibutyryl cyclic adenosine monophosphate on the induction of alkaline phosphatase in human fetal liver cell line. | 1989 | Biochim. Biophys. Acta | pmid:2535785 |
| Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
| Lau KH et al. | A mouse tumor-derived osteolytic factor stimulates bone resorption by a mechanism involving local prostaglandins production in bone. | 1985 | Biochim. Biophys. Acta | pmid:2986710 |
| Shimshoni JA et al. | Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder. | 2011 | Biochim. Biophys. Acta | pmid:21184843 |
| Al-Lahham SH et al. | Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. | 2010 | Biochim. Biophys. Acta | pmid:20691280 |
| Sun M et al. | The role of DDX3 in regulating Snail. | 2011 | Biochim. Biophys. Acta | pmid:21237216 |
| KUMAR S et al. | Location of butyric acid in bovine milk triglycerides. | 1960 | Biochim. Biophys. Acta | pmid:13755089 |
| Tiwari P et al. | Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. | 2016 | Biochimie | pmid:26655363 |
| Matta-el-Ammouri G et al. | Effects of butyric and acetic acids on acetone-butanol formation by Clostridium acetobutylicum. | 1987 | Biochimie | pmid:3032286 |
| Imai K et al. | The periodontal pathogen Porphyromonas gingivalis induces the Epstein-Barr virus lytic switch transactivator ZEBRA by histone modification. | 2012 | Biochimie | pmid:22178321 |
| Ballongue J et al. | [Role of acetate and butyrate in the induction of NADH: rubredoxin oxidoreductase in Clostridium acetobutylicum]. | 1986 | Biochimie | pmid:3091091 |
| Vimard C et al. | Changes in the sedimentation properties of acetycholinesterase during neuroblastoma differentiation. | 1976 | Biochimie | pmid:938691 |
| Edde B et al. | Changes in some cytoskeletal proteins during neuroblastoma cell differentiation. | 1982 | Biochimie | pmid:7066411 |
| VanGulck JF et al. | Predicting biogeochemical calcium precipitation in landfill leachate collection systems. | 2003 | Biodegradation | pmid:14571950 |