butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Fürll M et al. [Subacute butyric acid exposure in cattle. 5. Effect on the acid-base equilibrium and protein metabolism in cows]. 1990 Arch Exp Veterinarmed pmid:2102648
Fürll M and Dabbash MN [Subacute butyric acid exposure in cattle. 6. Effects of a butyric acid or a sodium butyrate exposure up to 2.0 g. per kg. body weight per day]. 1990 Arch Exp Veterinarmed pmid:2102649
Toide K Effects of the anti-dementia drug hopantenate calcium upon striatal dopaminergic neurons in young and aged rats. 1989 May-Jun Arch Int Pharmacodyn Ther pmid:2570556
Galzigna L et al. Properties of two derivatives of gamma-aminobutyric acid (GABA) capable of abolishing Cardiazol- and bicuculline-induced convulsions in the rat. 1978 Arch Int Pharmacodyn Ther pmid:736693
Yilmaz N Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases. 2012 Arch Med Sci pmid:22457688
Dayangac-Erden D et al. Carboxylic acid derivatives of histone deacetylase inhibitors induce full length SMN2 transcripts: a promising target for spinal muscular atrophy therapeutics. 2011 Arch Med Sci pmid:22291761
SANTAMARIA L and DE VINCENTIIS M [Not Available]. 1949 Jan-Feb Arch Sci Biol (Bologna) pmid:18114874
SANTAMARIA L and DE VINCENTIIS M [Not Available]. 1949 Jan-Feb Arch Sci Biol (Bologna) pmid:18124888
Bägli DJ et al. Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation. 1989 Arch Surg pmid:2910252
Parekh D et al. Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells. 1991 Arch Surg pmid:1706915
Yeh TS et al. Significance of cellular distribution of ezrin in pancreatic cystic neoplasms and ductal adenocarcinoma. 2005 Arch Surg pmid:16365240
Tappenden KA Emerging therapies for intestinal failure. 2010 Arch Surg pmid:20566971
Kaiser E et al. [Investigations on the fermentation quality of silage from low-nitrate green forage]. 1999 Arch Tierernahr pmid:10548978
Immig I et al. Attempts to induce reductive acetogenesis into a sheep rumen. 1996 Arch Tierernahr pmid:8988318
Kaiser E and Weiss K [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. 1997 Arch Tierernahr pmid:9324922
Chen T et al. Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. 2002 Arch. Biochem. Biophys. pmid:12464268
Moon MS et al. GAD 67KD antisense in colon cancer cells inhibits cell growth and sensitizes to butyrate and pH reduction and H2O2 and gamma-radiation. 2004 Arch. Biochem. Biophys. pmid:15369822
Ziegler K et al. Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4). 2016 Arch. Biochem. Biophys. pmid:26854723
Jensen BD et al. The efficiencies of the component steps of oxidative phosphorylation. II. Experimental determination of the efficiencies in mitochondria and examination of the equivalence of membrane potential and pH gradient in phosphorylation. 1986 Arch. Biochem. Biophys. pmid:3015029
Atkins KB et al. Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation. 1997 Arch. Biochem. Biophys. pmid:9224725
Morand C et al. Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. 1994 Arch. Biochem. Biophys. pmid:8135535
Matsui-Yuasa I et al. Two mechanisms of spermidine/spermine N1-acetyltransferase-induction. 1989 Arch. Biochem. Biophys. pmid:2463788
Cox GS and Park KH Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures. 1989 Arch. Biochem. Biophys. pmid:2463791
Cai J et al. Role of caspase activation in butyrate-induced terminal differentiation of HT29 colon carcinoma cells. 2004 Arch. Biochem. Biophys. pmid:15047183
Amano J et al. Comparative study of glycosyltransferase activities in Caco-2 cells before and after enterocytic differentiation using lectin-affinity high-performance liquid chromatography. 2001 Arch. Biochem. Biophys. pmid:11697856
Wright PS et al. Butyrate effects on normal and adapted hepatoma cells: morphological response and implications for vectoral cholesterol transport. 1986 Arch. Biochem. Biophys. pmid:3729417
Hung MW et al. Differential regulation of placental and germ cell alkaline phosphatases by glucocorticoid and sodium butyrate in human gastric carcinoma cell line TMK-1. 2001 Arch. Biochem. Biophys. pmid:11361139
Goto H et al. Effects of parathyroid hormone on ornithine decarboxylase activity in human osteosarcoma cells. 1991 Arch. Biochem. Biophys. pmid:1654784
Multhaup I et al. Conservation of the acetylation pattern of histones and the transcriptional activity in Ehrlich ascites tumor cells by sodium butyrate. 1983 Arch. Biochem. Biophys. pmid:6189452
McClure DS and Cox GS Glucose requirement for induction by sodium butyrate of the glycoprotein hormone alpha subunit in HeLa cells. 1984 Arch. Biochem. Biophys. pmid:6205630
Crane JK Redistribution of cyclic GMP in response to sodium butyrate in colon cells. 2000 Arch. Biochem. Biophys. pmid:10729202
Tamura RN and Cox GS Enhancement by theophylline of the butyrate-mediated induction of choriogonadotropin alpha-subunit in HeLa cells. I. Lack of correlation with cAMP. 1990 Arch. Biochem. Biophys. pmid:1693836
Cosgrove DE and Cox GS Enhancement by theophylline of the butyrate-mediated induction of choriogonadotropin alpha-subunit in HeLa cells. II. Effect of both agents on mRNA turnover. 1990 Arch. Biochem. Biophys. pmid:1693837
Marchant P et al. A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation. 1989 Arch. Biochem. Biophys. pmid:2757387
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Prasanna Kumar S et al. Butyrate-induced phosphatase regulates VEGF and angiogenesis via Sp1. 2008 Arch. Biochem. Biophys. pmid:18655767
Yamane M and Yamane S The induction of colonocyte differentiation in CaCo-2 cells by sodium butyrate causes an increase in glucosylceramide synthesis in order to avoid apoptosis based on ceramide. 2007 Arch. Biochem. Biophys. pmid:17303065
Bertrand E et al. Influence of histone hyperacetylation on nucleosomal particles as visualized by electron microscopy. 1984 Arch. Biochem. Biophys. pmid:6703701
MUKHERJEE S Studies on degradation of fats by microorganisms. III. The metabolism of butyric acid by A. niger. 1952 Arch. Biochem. Biophys. pmid:14915540
Jaskiewicz J et al. Catabolism of isobutyrate by colonocytes. 1996 Arch. Biochem. Biophys. pmid:8619613
Kawasaki N et al. Control of hemoglobin synthesis in erythroid differentiating K562 cells. I. Role of iron in erythroid cell heme synthesis. 1996 Arch. Biochem. Biophys. pmid:8645006
Tanaka Y et al. Effects of 1,25-dihydroxyvitamin D3 and its analogs on butyrate-induced differentiation of HT-29 human colonic carcinoma cells and on the reversal of the differentiated phenotype. 1990 Arch. Biochem. Biophys. pmid:2306105
Garrison PM et al. Effects of histone deacetylase inhibitors on the Ah receptor gene promoter. 2000 Arch. Biochem. Biophys. pmid:10666294
Calabrese V et al. Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. 2004 Arch. Biochem. Biophys. pmid:15488476
Poduslo SE Induction of ketone body enzymes in glial cells. 1989 Arch. Biochem. Biophys. pmid:2568818
Otto DA et al. Reciprocal effects of 5-(tetradecyloxy)-2-furoic acid on fatty acid oxidation. 1985 Arch. Biochem. Biophys. pmid:4051503
Kamitani H et al. Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate. 1999 Arch. Biochem. Biophys. pmid:10415110
Staecker JL and Pitot HC The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. 1988 Arch. Biochem. Biophys. pmid:2895606
Frerman FE The role of acetyl coenzyme A: butyrate coenzyme A in the transferase uptake of butyrate by isolated membrane vesicles of Escherichia coli. 1973 Arch. Biochem. Biophys. pmid:4593815
Jagielski AK et al. The role of intracellular cAMP in renal gluconeogenesis in view of differential action of various cAMP analogues. 2005 Arch. Biochem. Biophys. pmid:15639228
Herz F et al. Alkaline phosphatase in HT-29, a human colon cancer cell line: influence of sodium butyrate and hyperosmolality. 1981 Arch. Biochem. Biophys. pmid:7305346
Pynadath TI NADH-dependent synthesis of butyric acid by rabbit mammary gland mitochondrial enzymes. 1969 Arch. Biochem. Biophys. pmid:4390357
Griffin MJ et al. A study of adenosine 3':5'-cyclic monophosphate, sodium butyrate and cortisol as inducers of HeLa alkaline phosphatase. 1974 Arch. Biochem. Biophys. pmid:4376666
Cessna AJ and Grover R Exposure of ground-rig applicators to the herbicide bromoxynil applied as a 1:1 mixture of butyrate and octanoate. 2002 Arch. Environ. Contam. Toxicol. pmid:11910467
Sawicki J et al. Benzo(a)pyrene metabolism and metabolites binding to DNA in the presence of BHA. 1980 Arch. Geschwulstforsch. pmid:7458578
Zhu K et al. Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors. 2008 Arch. Gynecol. Obstet. pmid:17680259
Piotrowska H and Jagodzinski PP Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. 2009 Arch. Med. Res. pmid:19427965
Gerhardt A et al. Fermentation of 4-aminobutyrate by Clostridium aminobutyricum: cloning of two genes involved in the formation and dehydration of 4-hydroxybutyryl-CoA. 2000 Arch. Microbiol. pmid:11041350
Sass H et al. Desulfosporomusa polytropa gen. nov., sp. nov., a novel sulfate-reducing bacterium from sediments of an oligotrophic lake. 2004 Arch. Microbiol. pmid:15340785
Bräsen C and Schönheit P Unusual ADP-forming acetyl-coenzyme A synthetases from the mesophilic halophilic euryarchaeon Haloarcula marismortui and from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum. 2004 Arch. Microbiol. pmid:15340786
Russ L et al. Genome analysis and heterologous expression of acetate-activating enzymes in the anammox bacterium Kuenenia stuttgartiensis. 2012 Arch. Microbiol. pmid:22752113
Millais AJ et al. The biotransformation of t-butylacetonitrile and its boron-containing analogue trimethylamine-cyanoborane by Brevibacterium R312. 1997 Arch. Microbiol. pmid:9238109
Jones SL et al. Correlation of long-range membrane order with temperature-dependent growth characteristics of parent and a cold-sensitive, branched-chain-fatty-acid-deficient mutant of Listeria monocytogenes. 2002 Arch. Microbiol. pmid:11907677
Qiu YL et al. Sporotomaculum syntrophicum sp. nov., a novel anaerobic, syntrophic benzoate-degrading bacterium isolated from methanogenic sludge treating wastewater from terephthalate manufacturing. 2003 Arch. Microbiol. pmid:12605290
Pfeiffer N et al. Acetatifactor muris gen. nov., sp. nov., a novel bacterium isolated from the intestine of an obese mouse. 2012 Arch. Microbiol. pmid:22659832
Yokoyama S et al. Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. 2010 Arch. Microbiol. pmid:19904524
Ellington MJ et al. Regulation of the nap operon encoding the periplasmic nitrate reductase of Paracoccus pantotrophus: delineation of DNA sequences required for redox control. 2006 Arch. Microbiol. pmid:16333617
Janssen PH Propanol as an end product of threonine fermentation. 2004 Arch. Microbiol. pmid:15455192
Karlsson A et al. CO2-dependent fermentation of phenol to acetate, butyrate and benzoate by an anaerobic, pasteurised culture. 2000 May-Jun Arch. Microbiol. pmid:10896220
Macieira S et al. Crystal structure of the complex between 4-hydroxybutyrate CoA-transferase from Clostridium aminobutyricum and CoA. 2012 Arch. Microbiol. pmid:21833509
Roberts CM et al. The role of enoyl-coa hydratase in the metabolism of isoleucine by Pseudomonas putida. 1978 Arch. Microbiol. pmid:678016
Decroos K et al. Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions. 2005 Arch. Microbiol. pmid:15578160
Müller JA and Schink B Initial steps in the fermentation of 3-hydroxybenzoate by Sporotomaculum hydroxybenzoicum. 2000 Arch. Microbiol. pmid:10816048
Widdel F and Pfennig N Sporulation and further nutritional characteristics of Desulfotomaculum acetoxidans. 1981 Arch. Microbiol. pmid:7283637
Shively JM et al. Depression of the synthesis of the intermediate and large forms of ribulose-1,5-bisphosphate carboxylase/oxygenase in Rhodopseudomonas capsulata. 1984 Arch. Microbiol. pmid:6089690
Cunneen TS et al. In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. 2009 Arch. Ophthalmol. pmid:19365017
Sheng J et al. Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia. 2006 Arch. Oral Biol. pmid:16806047
Seagrave JC et al. The effect of NH4Cl on Rb+ fluxes in resting and stimulated rat submandibular acinar cells. 1992 Arch. Oral Biol. pmid:1280090
Seagrave JC et al. Intracellular pH changes induced by exposure to weak acids and bases in submandibular cells of early postnatal rats. 1992 Arch. Oral Biol. pmid:1384459
Huang CB et al. Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. 2011 Arch. Oral Biol. pmid:21333271
Zgorzynska E et al. Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. 2015 Arch. Oral Biol. pmid:25455128
Dzierzewicz Z et al. The role of Desulfovibrio desulfuricans lipopolysaccharides in modulation of periodontal inflammation through stimulation of human gingival fibroblasts. 2010 Arch. Oral Biol. pmid:20593542
Katono T et al. Sodium butyrate stimulates mineralized nodule formation and osteoprotegerin expression by human osteoblasts. 2008 Arch. Oral Biol. pmid:18406397
Iida T et al. Sodium butyrate induces the production of cyclooxygenases and prostaglandin Eâ‚‚ in ROS 17/2.8 osteoblastic cells. 2011 Arch. Oral Biol. pmid:21281931
Uematsu H et al. Degradation of arginine and other amino acids by butyrate-producing asaccharolytic anaerobic Gram-positive rods in periodontal pockets. 2003 Arch. Oral Biol. pmid:12749914
Faber J et al. Terminal deoxynucleotidyl transferase-negative acute lymphoblastic leukemia. 2000 Arch. Pathol. Lab. Med. pmid:10629138
Bajracharya P et al. Effect of different ingredients in traditional Korean medicine for human uterine leiomyoma on normal myometrial and leiomyomal smooth muscle cell proliferation. 2009 Arch. Pharm. Res. pmid:20091268
Ahn MY et al. Cytotoxicity and L-amino acid oxidase activity of crude insect drugs. 2000 Arch. Pharm. Res. pmid:11059827
Park NS et al. The crystal structure of KR-21042, an analgesic capsaicinoid. 2002 Arch. Pharm. Res. pmid:11887880
Hong YS et al. 1H NMR-based metabonomic assessment of probiotic effects in a colitis mouse model. 2010 Arch. Pharm. Res. pmid:20661720
Piao ZZ et al. Improved analytical validation and pharmacokinetics of valsartan using HPLC with UV detection. 2008 Arch. Pharm. Res. pmid:18787797
Kim SN et al. Regulation of adipocyte differentiation by histone deacetylase inhibitors. 2009 Arch. Pharm. Res. pmid:19407971
Kim YK et al. Isolation of flavonol rhamnosides from Loranthus tanakae and cytotoxic effect of them on human tumor cell lines. 2004 Arch. Pharm. Res. pmid:14969337
Cho SS et al. Quantitative analysis of nargenicin in Nocardia sp. CS682 culture by high performance liquid chromatography. 2009 Arch. Pharm. Res. pmid:19387575
Wobus AM and Löser P Present state and future perspectives of using pluripotent stem cells in toxicology research. 2011 Arch. Toxicol. pmid:21225242
Zapletal O et al. Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models. 2017 Arch. Toxicol. pmid:27830268
Clarke DO and Brown NA Valproic acid teratogenesis and embryonic lipid metabolism. 1987 Arch. Toxicol. Suppl. pmid:3115231
Asai S et al. Quantitative analysis of the Epstein-Barr virus-inducing properties of short-chain fatty acids present in the culture fluids of oral bacteria. 1991 Arch. Virol. pmid:1652240
Liang CY et al. High efficiency gene transfer into mammalian kidney cells using baculovirus vectors. 2004 Arch. Virol. pmid:14689275
Radsak K et al. Induction by sodium butyrate of cytomegalovirus replication in human endothelial cells. 1989 Arch. Virol. pmid:2552958