butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Lymphoma, AIDS-Related D016483 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Dementia, Vascular D015140 7 associated lipids
Hemorrhoids D006484 2 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Terova G et al. Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. 2016 PLoS ONE pmid:27471849
Jawed K et al. Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. 2016 PLoS ONE pmid:27466817
Gargari G et al. Consumption of a Bifidobacterium bifidum Strain for 4 Weeks Modulates Dominant Intestinal Bacterial Taxa and Fecal Butyrate in Healthy Adults. 2016 Appl. Environ. Microbiol. pmid:27451450
Teixeira C et al. Effects of variety and steeping conditions on some barley components associated with colonic health. 2016 J. Sci. Food Agric. pmid:27450418
Zhou J et al. Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. 2016 Lipids Health Dis pmid:27449927
Astakhova L et al. Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. 2016 PLoS ONE pmid:27441625
Frycz BA et al. Transcript level of AKR1C3 is down-regulated in gastric cancer. 2016 Biochem. Cell Biol. pmid:27019068
Li H et al. Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. 2016 Brain Res. pmid:27017959
Ortega JF et al. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. 2016 Oncotarget pmid:27013579
Sjöblom M et al. Catalytic upgrading of butyric acid towards fine chemicals and biofuels. 2016 FEMS Microbiol. Lett. pmid:26994015
Zhao Z et al. Potential enhancement of direct interspecies electron transfer for syntrophic metabolism of propionate and butyrate with biochar in up-flow anaerobic sludge blanket reactors. 2016 Bioresour. Technol. pmid:26967338
Tiwari P et al. Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. 2016 Biochimie pmid:26655363
Valvassori SS et al. Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. 2016 Psychiatry Res pmid:26654753
Mátis G et al. Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. 2016 J Anim Physiol Anim Nutr (Berl) pmid:26614344
Luceri C et al. Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. 2016 Dig Liver Dis pmid:26607831
Huang H et al. Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. 2016 Cell. Mol. Immunol. pmid:25683610
Neis EP et al. Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. 2016 PLoS ONE pmid:27835668
Khairy H et al. The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. 2016 Lett. Appl. Microbiol. pmid:27564089
Kong X et al. Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. 2016 Bioresour. Technol. pmid:26998799
Yan H and Ajuwon KM Mechanism of Butyrate Stimulation of Triglyceride Storage and Adipokine Expression during Adipogenic Differentiation of Porcine Stromovascular Cells. 2015 PLoS ONE pmid:26713737
Cui Y et al. Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast. 2015 PLoS ONE pmid:26710276
Jones RJ et al. Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. 2015 Bioresour. Technol. pmid:25898090
Tian H et al. Anaerobic co-digestion of kitchen waste and pig manure with different mixing ratios. 2015 J. Biosci. Bioeng. pmid:25617184
Zheng XT et al. Sodium butyrate down-regulates tristetraprolin-mediated cyclin B1 expression independent of the formation of processing bodies. 2015 Int. J. Biochem. Cell Biol. pmid:26555753
Deng Y et al. Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. 2015 J. Biotechnol. pmid:26535965
Durlak M et al. A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds. 2015 PLoS ONE pmid:26509275
Sasajima H et al. Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. 2015 Neurotoxicology pmid:26493152
Huang C et al. Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets. 2015 J. Nutr. pmid:26491121
Luo H et al. Enhancing Butanol Production under the Stress Environments of Co-Culturing Clostridium acetobutylicum/Saccharomyces cerevisiae Integrated with Exogenous Butyrate Addition. 2015 PLoS ONE pmid:26489085
Alva-Murillo N et al. The activation of the TLR2/p38 pathway by sodium butyrate in bovine mammary epithelial cells is involved in the reduction of Staphylococcus aureus internalization. 2015 Mol. Immunol. pmid:26471700
Turon V et al. Growth of Chlorella sorokiniana on a mixture of volatile fatty acids: The effects of light and temperature. 2015 Bioresour. Technol. pmid:26461792
Muñoz-Rugeles L and Alvarez-Idaboy JR A proton-electron sequential transfer mechanism: theoretical evidence about its biological relevance. 2015 Phys Chem Chem Phys pmid:26456543
Sari O et al. Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. 2015 Eur J Med Chem pmid:26451771
Jin CJ et al. Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). 2015 Br. J. Nutr. pmid:26450277
Nasser Al-Shorgani NK et al. Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1. 2015 Anaerobe pmid:26439644
Fomina-Yadlin D et al. Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression. 2015 J. Biotechnol. pmid:26325199
Patman G Gut microbiota: Lactobacillus acidophilus opens the door to butyrate. 2015 Nat Rev Gastroenterol Hepatol pmid:26323876
Desai VH et al. Receptor-Guided De Novo Design of Dengue Envelope Protein Inhibitors. 2015 Appl. Biochem. Biotechnol. pmid:26299376
Kumar A et al. Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26272259
Kumar P et al. Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. 2015 PLoS ONE pmid:26266541
Li L et al. Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. 2015 J. Food Sci. pmid:26256258
Shang HM et al. Effects of dietary polysaccharides from the submerged fermentation concentrate of Hericium caput-medusae (Bull.:Fr.) Pers. on fat deposition in broilers. 2015 J. Sci. Food Agric. pmid:24771556
Bucki R et al. Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. 2015 Antimicrob. Agents Chemother. pmid:26248361
Chen Y et al. Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. 2015 Cardiovasc Diabetol pmid:26245924
Wang X et al. Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway. 2015 Sci Rep pmid:26234821
Regestein L et al. Impact of butyric acid on butanol formation by Clostridium pasteurianum. 2015 Bioresour. Technol. pmid:26233327
Baroi GN et al. Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. 2015 Microb Biotechnol pmid:26230610
Zhong Y et al. Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. 2015 Food Funct pmid:26227569
Sandoval PY et al. Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. 2015 PLoS Genet. pmid:26218270
Valvassori SS et al. Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress. 2015 Curr Neurovasc Res pmid:26216027
Qaisrani SN et al. Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. 2015 Poult. Sci. pmid:26175052
Xu H et al. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26159698
Guglielmetti S and Riso P Reply to Conlon et al. 2015 J. Nutr. pmid:26125075
Fukushima A et al. Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats. 2015 Brain Res. pmid:26111645
Levy AW et al. Effect of feeding an encapsulated source of butyric acid (ButiPEARL) on the performance of male Cobb broilers reared to 42 d of age. 2015 Poult. Sci. pmid:26015588
Liu H et al. Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion. 2015 Pharmacol. Biochem. Behav. pmid:26013850
Chaturvedi K et al. Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles. 2015 Nanomedicine (Lond) pmid:26008194
Theparambil SM et al. Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes. 2015 J. Physiol. (Lond.) pmid:25990710
Chou YC et al. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells. 2015 Mol. Cell. Biol. pmid:25986606
Gurav A et al. Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. 2015 Biochem. J. pmid:25984582
Chen JH and Chou CC Acrylamide inhibits cellular differentiation of human neuroblastoma and glioblastoma cells. 2015 Food Chem. Toxicol. pmid:25959841
Conlon MA et al. Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. 2015 J. Nutr. pmid:25934666
Steckert AV et al. Effects of sodium butyrate on aversive memory in rats submitted to sepsis. 2015 Neurosci. Lett. pmid:25888815
Castino MR et al. Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats. 2015 PLoS ONE pmid:25880762
Ulfina GG et al. Modulation of post-partum reproductive performance in dairy cows through supplementation of long- or short-chain fatty acids during transition period. 2015 J Anim Physiol Anim Nutr (Berl) pmid:25879374
Blank M et al. Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats. 2015 Neurosci. Lett. pmid:25837444
Gonnella R et al. PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. 2015 Biochim. Biophys. Acta pmid:25827954
Shimoyama T et al. Study of the mechanisms of a Japanese traditional fermented medicine in the improvement of constipation. 2015 J. Gastroenterol. Hepatol. pmid:25827805
Huang YW et al. Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. 2015 PLoS ONE pmid:25826279
Chen L et al. Free and bound volatile chemicals in mulberry (Morus atropurpurea Roxb.). 2015 J. Food Sci. pmid:25817411
Cueno ME et al. High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. 2015 Cell Stress Chaperones pmid:25808460
Kanika G et al. Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. 2015 J. Biochem. Mol. Toxicol. pmid:25774002
Cao QF et al. TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. 2015 Cancer Biother. Radiopharm. pmid:25760728
Mackmull MT et al. Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). 2015 Mol. Cell Proteomics pmid:25755299
Li L et al. Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells. 2015 BMC Biochem. pmid:25592494
Henagan TM et al. Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. 2015 Br. J. Pharmacol. pmid:25559882
Weaver EM et al. Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. 2015 Eur. J. Pharmacol. pmid:25557765
Arai T et al. Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. 2015 J. Microbiol. Methods pmid:25555820
Shimizu T et al. Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells. 2015 J Physiol Sci pmid:25544596
Rodrigues MF et al. Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. 2015 J. Cell. Biochem. pmid:25510910
Huang C et al. Evaluating the possibility of using acetone-butanol-ethanol (ABE) fermentation wastewater for bacterial cellulose production by Gluconacetobacter xylinus. 2015 Lett. Appl. Microbiol. pmid:25615895
Ledaki I et al. Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. 2015 Oncotarget pmid:26305601
Tiwari P et al. Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. 2015 Chem. Biol. Interact. pmid:25478867
Varela RB et al. Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats. 2015 J Psychiatr Res pmid:25467060
Turon V et al. Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. 2015 Bioresour. Technol. pmid:25459841
Zgorzynska E et al. Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. 2015 Arch. Oral Biol. pmid:25455128
Lee C et al. Effect of 2-hydroxy-4-methylthio-butanoic acid on ruminal fermentation, bacterial distribution, digestibility, and performance of lactating dairy cows. 2015 J. Dairy Sci. pmid:25434334
Lopes-Borges J et al. Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain. 2015 Pharmacol. Biochem. Behav. pmid:25433326
Barichello T et al. Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis. 2015 Mol. Neurobiol. pmid:25284351
Mátis G et al. Effects of oral butyrate application on insulin signaling in various tissues of chickens. 2015 Domest. Anim. Endocrinol. pmid:25240231
Esteras N et al. G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. 2015 Mol. Neurobiol. pmid:25182869
Ray A et al. Absorption spectrophotometric, fluorescence and quantum chemical investigations on non-covalent interaction between PC₇₀BM and designed diporphyrin in solution. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25138385
Simon-O'Brien E et al. The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals. 2015 Addict Biol pmid:25041570
Szymanowska-Powałowska D and Kubiak P Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1. 2015 Appl. Microbiol. Biotechnol. pmid:25524700
Cottier F et al. MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. 2015 Eukaryotic Cell pmid:26297702
Dengler F et al. Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. 2015 J Anim Physiol Anim Nutr (Berl) pmid:24804847
Chen F et al. Unusual effects of monocarboxylic acids on the structure and on the transport and mechanical properties of chitosan films. 2015 Carbohydr Polym pmid:26256366
Katsou E et al. Coupling the treatment of low strength anaerobic effluent with fermented biowaste for nutrient removal via nitrite. 2015 J. Environ. Manage. pmid:25463576
Pawelka AJ and Huizinga JD Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25540235
Xiong XR et al. Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. 2015 Zygote pmid:23759515