butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Lymphoma, AIDS-Related D016483 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Dementia, Vascular D015140 7 associated lipids
Hemorrhoids D006484 2 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Jones RJ et al. Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. 2015 Bioresour. Technol. pmid:25898090
Durlak M et al. A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds. 2015 PLoS ONE pmid:26509275
Sasajima H et al. Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. 2015 Neurotoxicology pmid:26493152
Huang C et al. Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets. 2015 J. Nutr. pmid:26491121
Luo H et al. Enhancing Butanol Production under the Stress Environments of Co-Culturing Clostridium acetobutylicum/Saccharomyces cerevisiae Integrated with Exogenous Butyrate Addition. 2015 PLoS ONE pmid:26489085
Alva-Murillo N et al. The activation of the TLR2/p38 pathway by sodium butyrate in bovine mammary epithelial cells is involved in the reduction of Staphylococcus aureus internalization. 2015 Mol. Immunol. pmid:26471700
Kumar A et al. Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26272259
Kumar P et al. Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. 2015 PLoS ONE pmid:26266541
Li L et al. Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. 2015 J. Food Sci. pmid:26256258
Bucki R et al. Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. 2015 Antimicrob. Agents Chemother. pmid:26248361
Chen Y et al. Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. 2015 Cardiovasc Diabetol pmid:26245924
Wang X et al. Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway. 2015 Sci Rep pmid:26234821
Regestein L et al. Impact of butyric acid on butanol formation by Clostridium pasteurianum. 2015 Bioresour. Technol. pmid:26233327
Baroi GN et al. Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. 2015 Microb Biotechnol pmid:26230610
Gurav A et al. Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. 2015 Biochem. J. pmid:25984582
Chen JH and Chou CC Acrylamide inhibits cellular differentiation of human neuroblastoma and glioblastoma cells. 2015 Food Chem. Toxicol. pmid:25959841
Conlon MA et al. Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. 2015 J. Nutr. pmid:25934666
Steckert AV et al. Effects of sodium butyrate on aversive memory in rats submitted to sepsis. 2015 Neurosci. Lett. pmid:25888815
Castino MR et al. Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats. 2015 PLoS ONE pmid:25880762
Ulfina GG et al. Modulation of post-partum reproductive performance in dairy cows through supplementation of long- or short-chain fatty acids during transition period. 2015 J Anim Physiol Anim Nutr (Berl) pmid:25879374
Blank M et al. Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats. 2015 Neurosci. Lett. pmid:25837444
Gonnella R et al. PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. 2015 Biochim. Biophys. Acta pmid:25827954
Henagan TM et al. Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. 2015 Br. J. Pharmacol. pmid:25559882
Weaver EM et al. Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. 2015 Eur. J. Pharmacol. pmid:25557765
Arai T et al. Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. 2015 J. Microbiol. Methods pmid:25555820
Shimizu T et al. Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells. 2015 J Physiol Sci pmid:25544596
Rodrigues MF et al. Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. 2015 J. Cell. Biochem. pmid:25510910
Ledaki I et al. Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. 2015 Oncotarget pmid:26305601
Tiwari P et al. Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. 2015 Chem. Biol. Interact. pmid:25478867
Esteras N et al. G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. 2015 Mol. Neurobiol. pmid:25182869
Ray A et al. Absorption spectrophotometric, fluorescence and quantum chemical investigations on non-covalent interaction between PC₇₀BM and designed diporphyrin in solution. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25138385
Szymanowska-Powałowska D and Kubiak P Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1. 2015 Appl. Microbiol. Biotechnol. pmid:25524700
Cottier F et al. MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. 2015 Eukaryotic Cell pmid:26297702
Chen F et al. Unusual effects of monocarboxylic acids on the structure and on the transport and mechanical properties of chitosan films. 2015 Carbohydr Polym pmid:26256366
Pawelka AJ and Huizinga JD Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25540235
Xiong XR et al. Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. 2015 Zygote pmid:23759515
Stertz L et al. Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. 2014 Jan-Mar Rev Bras Psiquiatr pmid:24346357
Lu R et al. Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. 2014 J. Periodont. Res. pmid:25340203
Grousseau E et al. Phosphorus limitation strategy to increase propionic acid flux towards 3-hydroxyvaleric acid monomers in Cupriavidus necator. 2014 Bioresour. Technol. pmid:24365742
Wang C et al. A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. 2014 Anim. Sci. J. pmid:23638801
Unno T et al. Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats. 2014 J. Nutr. Sci. Vitaminol. pmid:25078378
Vidrine K et al. Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. 2014 Obesity (Silver Spring) pmid:23630079
Yu M et al. Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells. 2014 Mol. Carcinog. pmid:23359532
Szymanowska-Powałowska D et al. Biotechnological potential of Clostridium butyricum bacteria. 2014 Braz. J. Microbiol. pmid:25477923
Procentese A et al. Continuous xylose fermentation by Clostridium acetobutylicum--kinetics and energetics issues under acidogenesis conditions. 2014 Bioresour. Technol. pmid:24852648
Kondo Y et al. Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. 2014 PLoS ONE pmid:25084468
Vargas JE et al. Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells. 2014 Biochem. Cell Biol. pmid:25070040
Ozadali K et al. Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. 2014 Bioorg. Med. Chem. Lett. pmid:24631185
Shen H et al. BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. 2014 J. Cell. Mol. Med. pmid:24571310
Karki P et al. Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. 2014 Mol. Cell. Biol. pmid:24469401
Pérez-Carro R et al. Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. 2014 Clin. Genet. pmid:23895425
Jin H et al. Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. 2014 J. Biol. Chem. pmid:25342743
Ferrario C et al. Modulation of fecal Clostridiales bacteria and butyrate by probiotic intervention with Lactobacillus paracasei DG varies among healthy adults. 2014 J. Nutr. pmid:25332478
Gong Q et al. [Sodium butyrate inhibits HMGB1 expression and release and attenuates concanavalin A-induced acute liver injury in mice]. 2014 Sheng Li Xue Bao pmid:25332009
Pal A and Dey J Organogelation by 4-(N-tetradecanoyl)aminohydroxybutyric acids: effect of hydrogen-bonding group in the amphiphile head. 2014 J Phys Chem B pmid:25310731
Lorenzo JM Influence of the type of fiber coating and extraction time on foal dry-cured loin volatile compounds extracted by solid-phase microextraction (SPME). 2014 Meat Sci. pmid:23896153
Khalil NA et al. In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet. 2014 Int J Food Sci Nutr pmid:23941288
Kanski R et al. Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. 2014 J. Cell. Sci. pmid:25128567
Lee JM et al. Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. 2014 ChemSusChem pmid:25123894
Lopez CA et al. Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. 2014 Cell Host Microbe pmid:25121745
Cho HJ and Song MJ A gammaherpesvirus establishes persistent infection in neuroblastoma cells. 2014 Mol. Cells pmid:25092213
Li S et al. High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. 2014 J. Anim. Sci. pmid:25085388
Shin J et al. The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. 2014 J. Biol. Chem. pmid:25037223
Weber TE et al. Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. 2014 J. Anim. Sci. pmid:25023805
Nakata S et al. Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. 2014 Int. J. Oncol. pmid:25017791
Gutiérrez Acosta OB et al. Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. 2014 BMC Genomics pmid:25012398
Farkas O et al. Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system. 2014 J. Anim. Sci. pmid:24987069
Yang F et al. Sodium butyrate protects against toxin-induced acute liver failure in rats. 2014 HBPD INT pmid:24919615
Peterson EC and Daugulis AJ The use of high pressure CO2 -facilitated pH swings to enhance in situ product recovery of butyric acid in a two-phase partitioning bioreactor. 2014 Biotechnol. Bioeng. pmid:24888558
Tiwari P and Gupta KP Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. 2014 Toxicol. Appl. Pharmacol. pmid:24792773
Lin Y et al. Use of sodium butyrate as an alternative to dietary fiber: effects on the embryonic development and anti-oxidative capacity of rats. 2014 PLoS ONE pmid:24852604
Pasvolsky R et al. Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. 2014 Int. J. Food Microbiol. pmid:24801271
Maggio A et al. Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. 2014 Int. J. Radiat. Oncol. Biol. Phys. pmid:24803033
Ellis JT et al. Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. 2014 Can. J. Microbiol. pmid:24898684
Ochiai K and Kurita-Ochiai T [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. 2014 Nippon Yakurigaku Zasshi pmid:25109521
Liu W et al. Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. 2014 Br. J. Nutr. pmid:24774835
Ladirat SE et al. Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. 2014 Br. J. Nutr. pmid:24925303
Krokowicz L et al. Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis--a prospective randomized study. 2014 Int J Colorectal Dis pmid:24343275
Sanchez R et al. Differential abundance of IGF1, bile acids, and the genes involved in their signaling in the dominant follicle microenvironment of lactating cows and nulliparous heifers. 2014 Theriogenology pmid:24503106
Leon Carrion S et al. Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation. 2014 Exp. Dermatol. pmid:24451036
Cueno ME et al. Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease. 2014 Cell Stress Chaperones pmid:24052229
Aguilar EC et al. Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation. 2014 Nutr Metab Cardiovasc Dis pmid:24602606
Lee KH et al. Hizikia fusiformis fractions successfully improve atopic dermatitis indices in anti-CD3-stimulated splenocytes and 2,4-dinitrochlorobenzene-treated BALB/c mice. 2014 J. Pharm. Pharmacol. pmid:24354475
Sabra W et al. Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. 2014 Appl. Microbiol. Biotechnol. pmid:24584460
Blank M et al. Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. 2014 Neurobiol Learn Mem pmid:24583371
Possebom G et al. Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. 2014 J. Sci. Food Agric. pmid:24578290
Zhang Z et al. Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. 2014 Cell Reprogram pmid:24568633
Bolhari B et al. Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. 2014 J Endod pmid:24565666
Ai B et al. Butyric acid fermentation of sodium hydroxide pretreated rice straw with undefined mixed culture. 2014 J. Microbiol. Biotechnol. pmid:24561721
Hong JK et al. Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. 2014 Appl. Microbiol. Biotechnol. pmid:24557571
Liu Y et al. Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. 2014 Biotechnol. Lett. pmid:24557070
Hu X et al. Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. 2014 Dev. Growth Differ. pmid:24494796
Singh V et al. Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia. 2014 Neuroscience pmid:24480366
Rivkin I et al. Cancer cell sensitization and improved treatment efficacy by combined sodium butyrate and paclitaxel formulations is cancer-type specific. 2014 Int J Pharm pmid:24370842
Aoyama Y et al. Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor. 2014 Int. J. Neuropsychopharmacol. pmid:24345457
Górka P et al. Effect of method of delivery of sodium butyrate on maturation of the small intestine in newborn calves. 2014 J. Dairy Sci. pmid:24342681
Khan S and Jena GB Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. 2014 Chem. Biol. Interact. pmid:24530320
Ferreira AC et al. Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. 2014 Ann. Hematol. pmid:24577510
Meehan CJ and Beiko RG A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. 2014 Genome Biol Evol pmid:24625961
Pan Y et al. Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. 2014 Technol. Cancer Res. Treat. pmid:23919394