| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphoma, AIDS-Related | D016483 | 2 associated lipids |
| Pleural Effusion, Malignant | D016066 | 6 associated lipids |
| Milk Hypersensitivity | D016269 | 4 associated lipids |
| Urea Cycle Disorders, Inborn | D056806 | 2 associated lipids |
| Prostatic Neoplasms, Castration-Resistant | D064129 | 3 associated lipids |
| Dementia, Vascular | D015140 | 7 associated lipids |
| Hemorrhoids | D006484 | 2 associated lipids |
| Diverticulitis, Colonic | D004239 | 1 associated lipids |
| Diverticulosis, Colonic | D043963 | 1 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moon MS et al. | GAD 67KD antisense in colon cancer cells inhibits cell growth and sensitizes to butyrate and pH reduction and H2O2 and gamma-radiation. | 2004 | Arch. Biochem. Biophys. | pmid:15369822 |
| Morand C et al. | Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. | 1994 | Arch. Biochem. Biophys. | pmid:8135535 |
| Amano J et al. | Comparative study of glycosyltransferase activities in Caco-2 cells before and after enterocytic differentiation using lectin-affinity high-performance liquid chromatography. | 2001 | Arch. Biochem. Biophys. | pmid:11697856 |
| Hung MW et al. | Differential regulation of placental and germ cell alkaline phosphatases by glucocorticoid and sodium butyrate in human gastric carcinoma cell line TMK-1. | 2001 | Arch. Biochem. Biophys. | pmid:11361139 |
| Goto H et al. | Effects of parathyroid hormone on ornithine decarboxylase activity in human osteosarcoma cells. | 1991 | Arch. Biochem. Biophys. | pmid:1654784 |
| Multhaup I et al. | Conservation of the acetylation pattern of histones and the transcriptional activity in Ehrlich ascites tumor cells by sodium butyrate. | 1983 | Arch. Biochem. Biophys. | pmid:6189452 |
| Marchant P et al. | A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation. | 1989 | Arch. Biochem. Biophys. | pmid:2757387 |
| Sharma P et al. | Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. | 2013 | Arch. Biochem. Biophys. | pmid:23149273 |
| Yamane M and Yamane S | The induction of colonocyte differentiation in CaCo-2 cells by sodium butyrate causes an increase in glucosylceramide synthesis in order to avoid apoptosis based on ceramide. | 2007 | Arch. Biochem. Biophys. | pmid:17303065 |
| Bertrand E et al. | Influence of histone hyperacetylation on nucleosomal particles as visualized by electron microscopy. | 1984 | Arch. Biochem. Biophys. | pmid:6703701 |
| MUKHERJEE S | Studies on degradation of fats by microorganisms. III. The metabolism of butyric acid by A. niger. | 1952 | Arch. Biochem. Biophys. | pmid:14915540 |
| Calabrese V et al. | Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. | 2004 | Arch. Biochem. Biophys. | pmid:15488476 |
| Poduslo SE | Induction of ketone body enzymes in glial cells. | 1989 | Arch. Biochem. Biophys. | pmid:2568818 |
| Kamitani H et al. | Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate. | 1999 | Arch. Biochem. Biophys. | pmid:10415110 |
| Frerman FE | The role of acetyl coenzyme A: butyrate coenzyme A in the transferase uptake of butyrate by isolated membrane vesicles of Escherichia coli. | 1973 | Arch. Biochem. Biophys. | pmid:4593815 |
| Jagielski AK et al. | The role of intracellular cAMP in renal gluconeogenesis in view of differential action of various cAMP analogues. | 2005 | Arch. Biochem. Biophys. | pmid:15639228 |
| Herz F et al. | Alkaline phosphatase in HT-29, a human colon cancer cell line: influence of sodium butyrate and hyperosmolality. | 1981 | Arch. Biochem. Biophys. | pmid:7305346 |
| Griffin MJ et al. | A study of adenosine 3':5'-cyclic monophosphate, sodium butyrate and cortisol as inducers of HeLa alkaline phosphatase. | 1974 | Arch. Biochem. Biophys. | pmid:4376666 |
| Kaiser E et al. | [Investigations on the fermentation quality of silage from low-nitrate green forage]. | 1999 | Arch Tierernahr | pmid:10548978 |
| Immig I et al. | Attempts to induce reductive acetogenesis into a sheep rumen. | 1996 | Arch Tierernahr | pmid:8988318 |
| Kaiser E and Weiss K | [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. | 1997 | Arch Tierernahr | pmid:9324922 |
| Bägli DJ et al. | Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation. | 1989 | Arch Surg | pmid:2910252 |
| Parekh D et al. | Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells. | 1991 | Arch Surg | pmid:1706915 |
| Yeh TS et al. | Significance of cellular distribution of ezrin in pancreatic cystic neoplasms and ductal adenocarcinoma. | 2005 | Arch Surg | pmid:16365240 |
| Tappenden KA | Emerging therapies for intestinal failure. | 2010 | Arch Surg | pmid:20566971 |
| SANTAMARIA L and DE VINCENTIIS M | [Not Available]. | 1949 Jan-Feb | Arch Sci Biol (Bologna) | pmid:18114874 |
| SANTAMARIA L and DE VINCENTIIS M | [Not Available]. | 1949 Jan-Feb | Arch Sci Biol (Bologna) | pmid:18124888 |
| Yilmaz N | Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases. | 2012 | Arch Med Sci | pmid:22457688 |
| Dayangac-Erden D et al. | Carboxylic acid derivatives of histone deacetylase inhibitors induce full length SMN2 transcripts: a promising target for spinal muscular atrophy therapeutics. | 2011 | Arch Med Sci | pmid:22291761 |
| Toide K | Effects of the anti-dementia drug hopantenate calcium upon striatal dopaminergic neurons in young and aged rats. | 1989 May-Jun | Arch Int Pharmacodyn Ther | pmid:2570556 |
| Galzigna L et al. | Properties of two derivatives of gamma-aminobutyric acid (GABA) capable of abolishing Cardiazol- and bicuculline-induced convulsions in the rat. | 1978 | Arch Int Pharmacodyn Ther | pmid:736693 |
| Said A et al. | [The effect of intravenous administration of butyrate, isobutyrate, isovalerate and capronate to calves, young cattle and cattle on the blood plasma levels of glucose, insulin, free fatty acids and total alpha-amino-nitrogen]. | 1986 | Arch Exp Veterinarmed | pmid:3524499 |
| Said A et al. | [The effect of intravenous administration of butyrate, isobutyrate, isovalerate and capronate on the blood plasma levels in sheep of glucose, insulin, free fatty acids and total alpha-amino-nitrogen]. | 1986 | Arch Exp Veterinarmed | pmid:3524500 |
| Fürll M et al. | [Subacute butyric acid exposure in cattle. 5. Effect on the acid-base equilibrium and protein metabolism in cows]. | 1990 | Arch Exp Veterinarmed | pmid:2102648 |
| Fürll M and Dabbash MN | [Subacute butyric acid exposure in cattle. 6. Effects of a butyric acid or a sodium butyrate exposure up to 2.0 g. per kg. body weight per day]. | 1990 | Arch Exp Veterinarmed | pmid:2102649 |
| Müller I et al. | [Effect of the intravenous infusion of butyrate, isobutyrate and isovalerate on the blood serum levels of glucose, insulin, free fatty acids and total alpha-amino-N in sheep under conditions of adequate feeding and after an 8-day fast]. | 1985 | Arch Exp Veterinarmed | pmid:3888137 |
| Düsedau K et al. | [The effect of intravenous administration of butyrate, isobutyrate and isovalerate to lambs aged 8-45 days on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N]. | 1989 | Arch Exp Veterinarmed | pmid:2673127 |
| Kitano Y | Stimulation by melanocyte stimulating hormone and dibutyryl adenosine 3'5'-cyclic monophosphate of DNA synthesis in human melanocytes in vitro. | 1976 | Arch Dermatol Res | pmid:188388 |
| Polano MK and Ponec M | Dependence of corticosteroid penetration on the vehicle. | 1976 | Arch Dermatol | pmid:1275523 |
| KING TE and CHELDELIN VH | Pantothenic acid studies; the influence of glutamic acid and pantoic acid on yeast growth. | 1948 | Arch Biochem | pmid:18900106 |
| Tamura A et al. | Different effects of difructose anhydride III and inulin-type fructans on caecal microbiota in rats. | 2006 | Arch Anim Nutr | pmid:17036745 |
| Van Nevel CJ et al. | Incorporation of galactomannans in the diet of newly weaned piglets: effect on bacteriological and some morphological characteristics of the small intestine. | 2005 | Arch Anim Nutr | pmid:16080306 |
| Lv S et al. | Effects of extrusion of corn on growth performance, nutrient digestibility and short-chain fatty acid profiles in the hindgut of weaned piglets. | 2006 | Arch Anim Nutr | pmid:16649579 |
| Zduńczyk Z et al. | Performance and caecal adaptation of turkeys to diets without or with antibiotic and with different levels of mannan-oligosaccharide. | 2004 | Arch Anim Nutr | pmid:15595620 |
| Zacharias B et al. | The influence of 5% and 10% dietary apple pectin on parameters of fermentation in faeces and caecal digesta of weaning pigs. | 2004 | Arch Anim Nutr | pmid:15195908 |
| Zduńczyk Z et al. | Biological properties of fructooligosaccharides with different contents of kestose and nystose in rats. | 2005 | Arch Anim Nutr | pmid:16320813 |
| Eberhard M et al. | Effect of inulin supplementation on selected gastric, duodenal, and caecal microbiota and short chain fatty acid pattern in growing piglets. | 2007 | Arch Anim Nutr | pmid:17760302 |
| Shen Z et al. | Intraruminal infusion of n-butyric acid induces an increase of ruminal papillae size independent of IGF-1 system in castrated bulls. | 2005 | Arch Anim Nutr | pmid:16320810 |
| Hezayen FF et al. | Polymer production by two newly isolated extremely halophilic archaea: application of a novel corrosion-resistant bioreactor. | 2000 | Appl. Microbiol. Biotechnol. | pmid:11030566 |
| Paczkowski S and Schütz S | Post-mortem volatiles of vertebrate tissue. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21720824 |
| Temudo MF et al. | Xylose anaerobic conversion by open-mixed cultures. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19015850 |
| Dar SA et al. | Competition and coexistence of sulfate-reducing bacteria, acetogens and methanogens in a lab-scale anaerobic bioreactor as affected by changing substrate to sulfate ratio. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18305937 |
| Teng SX et al. | Electricity generation from mixed volatile fatty acids using microbial fuel cells. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20607228 |
| Janssen H et al. | A proteomic and transcriptional view of acidogenic and solventogenic steady-state cells of Clostridium acetobutylicum in a chemostat culture. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20617312 |
| Fischer CR et al. | Assessment of heterologous butyrate and butanol pathway activity by measurement of intracellular pathway intermediates in recombinant Escherichia coli. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20625717 |
| Stams AJ et al. | Citric acid wastewater as electron donor for biological sulfate reduction. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19399495 |
| Volova TG et al. | Autotrophic synthesis of polyhydroxyalkanoates by the bacteria Ralstonia eutropha in the presence of carbon monoxide. | 2002 | Appl. Microbiol. Biotechnol. | pmid:11956753 |
| Lehmann D et al. | New insights into the butyric acid metabolism of Clostridium acetobutylicum. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22576943 |
| Wietzke M and Bahl H | The redox-sensing protein Rex, a transcriptional regulator of solventogenesis in Clostridium acetobutylicum. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22576944 |
| Lecouturier D et al. | Enrichment and properties of an anaerobic mixed culture that reductively deiodinates 5-amino-2,4,6-triiodoisophthalic acid, an X-ray contrast agent precursor. | 2003 | Appl. Microbiol. Biotechnol. | pmid:12845492 |
| Junicke H et al. | Kinetic and thermodynamic control of butyrate conversion in non-defined methanogenic communities. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26403924 |
| Milliken CE and May HD | Sustained generation of electricity by the spore-forming, Gram-positive, Desulfitobacterium hafniense strain DCB2. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17031638 |
| Dar SA et al. | Co-existence of physiologically similar sulfate-reducing bacteria in a full-scale sulfidogenic bioreactor fed with a single organic electron donor. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17440719 |
| Timmers RA et al. | Microbial community structure elucidates performance of Glyceria maxima plant microbial fuel cell. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22361855 |
| Kim MD et al. | Growth condition and bacterial community for maximum hydrolysis of suspended organic materials in anaerobic digestion of food waste-recycling wastewater. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19894044 |
| Liu SJ and Steinbüchel A | Exploitation of butyrate kinase and phosphotransbutyrylase from Clostridium acetobutylicum for the in vitro biosynthesis of poly(hydroxyalkanoic acid). | 2000 | Appl. Microbiol. Biotechnol. | pmid:10855714 |
| Balk M et al. | Methanol utilizing Desulfotomaculum species utilizes hydrogen in a methanol-fed sulfate-reducing bioreactor. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17028873 |
| Kuit W et al. | Disruption of the acetate kinase (ack) gene of Clostridium acetobutylicum results in delayed acetate production. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22249720 |
| Yang YH et al. | Optimization of growth media components for polyhydroxyalkanoate (PHA) production from organic acids by Ralstonia eutropha. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20535466 |
| Gao X et al. | Engineered polyketide biosynthesis and biocatalysis in Escherichia coli. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20853106 |
| Balk M et al. | (Per)chlorate reduction by an acetogenic bacterium, Sporomusa sp., isolated from an underground gas storage. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20680263 |
| Tsueng G et al. | Unique butyric acid incorporation patterns for salinosporamides A and B reveal distinct biosynthetic origins. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17340108 |
| Thrash JC et al. | Description of the novel perchlorate-reducing bacteria Dechlorobacter hydrogenophilus gen. nov., sp. nov.and Propionivibrio militaris, sp. nov. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19921177 |
| Lehmann D et al. | Modifying the product pattern of Clostridium acetobutylicum: physiological effects of disrupting the acetate and acetone formation pathways. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22246530 |
| Fu Z and Holtzapple MT | Anaerobic thermophilic fermentation for carboxylic acid production from in-storage air-lime-treated sugarcane bagasse. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21365471 |
| Lu XY et al. | Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. | 2004 | Appl. Microbiol. Biotechnol. | pmid:12920488 |
| Rehdorf J et al. | Pseudomonas putida esterase contains a GGG(A)X-motif confering activity for the kinetic resolution of tertiary alcohols. | 2012 | Appl. Microbiol. Biotechnol. | pmid:21779846 |
| Tang YQ et al. | Effect of dilution rate on the microbial structure of a mesophilic butyrate-degrading methanogenic community during continuous cultivation. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17221191 |
| Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid. | 2013 | Appl. Microbiol. Biotechnol. | pmid:24013291 |
| Chatterjee S and Karlovsky P | Removal of the endocrine disrupter butyl benzyl phthalate from the environment. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20396882 |
| Szymanowska-Powałowska D and Kubiak P | Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25524700 |
| Torres CI et al. | Kinetics of consumption of fermentation products by anode-respiring bacteria. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17909786 |
| Popp D et al. | The alkaloid gramine in the anaerobic digestion process-inhibition and adaptation of the methanogenic community. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27138201 |
| Zhang J et al. | Metabolic engineering of Clostridium tyrobutyricum for n-butanol production from sugarcane juice. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28238080 |
| Sabra W et al. | Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24584460 |
| Tzortzis G et al. | In vitro evaluation of the fermentation properties of galactooligosaccharides synthesised by alpha-galactosidase from Lactobacillus reuteri. | 2004 | Appl. Microbiol. Biotechnol. | pmid:13680200 |
| Yasohara Y et al. | Synthesis of optically active ethyl 4-chloro-3-hydroxybutanoate by microbial reduction. | 1999 | Appl. Microbiol. Biotechnol. | pmid:10422229 |
| Millat T and Winzer K | Mathematical modelling of clostridial acetone-butanol-ethanol fermentation. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28210797 |
| RodrÃguez E et al. | Molecular analysis of the biomass of a fluidized bed reactor treating synthetic vinasse at anaerobic and micro-aerobic conditions. | 2012 | Appl. Microbiol. Biotechnol. | pmid:21861082 |
| Hong JK et al. | Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24557571 |
| Jeon BS et al. | Production of hexanoic acid from D-galactitol by a newly isolated Clostridium sp. BS-1. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20721546 |
| Maeda H et al. | Purification and characterization of a biodegradable plastic-degrading enzyme from Aspergillus oryzae. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15968570 |
| Zhang C et al. | Differential effect of early antibiotic intervention on bacterial fermentation patterns and mucosal gene expression in the colon of pigs under diets with different protein levels. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27913852 |
| Seco EM et al. | The pcsA gene from Streptomyces diastaticus var. 108 encodes a polyene carboxamide synthase with broad substrate specificity for polyene amides biosynthesis. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19707755 |
| Wang YQ et al. | Enhancement of acetate productivity in a thermophilic (55 °C) hollow-fiber membrane biofilm reactor with mixed culture syngas (H/CO) fermentation. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28110397 |
| Tanaka S et al. | Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L. | 2016 | Appl. Environ. Microbiol. | pmid:26921420 |
| Kristiansen A et al. | Butyric acid- and dimethyl disulfide-assimilating microorganisms in a biofilter treating air emissions from a livestock facility. | 2011 | Appl. Environ. Microbiol. | pmid:22003018 |
| Zhao Y et al. | Expression of a cloned cyclopropane fatty acid synthase gene reduces solvent formation in Clostridium acetobutylicum ATCC 824. | 2003 | Appl. Environ. Microbiol. | pmid:12732555 |
| Bowles LK and Ellefson WL | Effects of butanol on Clostridium acetobutylicum. | 1985 | Appl. Environ. Microbiol. | pmid:2868690 |
| Van Lier JB et al. | Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. | 1993 | Appl. Environ. Microbiol. | pmid:8476278 |