butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Lymphoma, AIDS-Related D016483 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Dementia, Vascular D015140 7 associated lipids
Hemorrhoids D006484 2 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Ohkura S et al. Novel escape mutants suggest an extensive TRIM5α binding site spanning the entire outer surface of the murine leukemia virus capsid protein. 2011 PLoS Pathog. pmid:21483490
Kang H et al. Coordination of KSHV latent and lytic gene control by CTCF-cohesin mediated chromosome conformation. 2011 PLoS Pathog. pmid:21876668
Waszkielewicz A and Bojarski J Gamma-hydrobutyric acid (GHB) and its chemical modifications: a review of the GHBergic system. 2004 Jan-Feb Pol J Pharmacol pmid:15047976
Gałecka M et al. Faecalibacterium prausnitzii and Crohn's disease - is there any connection? 2013 Pol. J. Microbiol. pmid:23829084
Song M et al. Effects of topical treatment of sodium butyrate and 5-aminosalicylic acid on expression of trefoil factor 3, interleukin 1beta, and nuclear factor kappaB in trinitrobenzene sulphonic acid induced colitis in rats. 2006 Postgrad Med J pmid:16461476
Van Immerseel F et al. Supplementation of coated butyric acid in the feed reduces colonization and shedding of Salmonella in poultry. 2005 Poult. Sci. pmid:16479940
Namkung H et al. Antimicrobial activity of butyrate glycerides toward Salmonella Typhimurium and Clostridium perfringens. 2011 Poult. Sci. pmid:21934003
Rebolé A et al. Effects of inulin and enzyme complex, individually or in combination, on growth performance, intestinal microflora, cecal fermentation characteristics, and jejunal histomorphology in broiler chickens fed a wheat- and barley-based diet. 2010 Poult. Sci. pmid:20075280
Leeson S et al. Effect of butyric acid on the performance and carcass yield of broiler chickens. 2005 Poult. Sci. pmid:16206563
Kaczmarek SA et al. Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. 2016 Poult. Sci. pmid:26740137
Donalson LM et al. In vitro fermentation response of laying hen cecal bacteria to combinations of fructooligosaccharide prebiotics with alfalfa or a layer ration. 2008 Poult. Sci. pmid:18577604
Zhang WH et al. Dietary sodium butyrate alleviates the oxidative stress induced by corticosterone exposure and improves meat quality in broiler chickens. 2011 Poult. Sci. pmid:22010246
Zhang WF et al. Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. 2003 Poult. Sci. pmid:12710488
Jerzsele A et al. Efficacy of protected sodium butyrate, a protected blend of essential oils, their combination, and Bacillus amyloliquefaciens spore suspension against artificially induced necrotic enteritis in broilers. 2012 Poult. Sci. pmid:22399722
Qaisrani SN et al. Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. 2015 Poult. Sci. pmid:26175052
Rehman H et al. Effects of dietary inulin on the intestinal short chain fatty acids and microbial ecology in broiler chickens as revealed by denaturing gradient gel electrophoresis. 2008 Poult. Sci. pmid:18340001
Levy AW et al. Effect of feeding an encapsulated source of butyric acid (ButiPEARL) on the performance of male Cobb broilers reared to 42 d of age. 2015 Poult. Sci. pmid:26015588
Faber TA et al. The effects of a galactoglucomannan oligosaccharide-arabinoxylan (GGMO-AX) complex in broiler chicks challenged with Eimeria acervulina. 2012 Poult. Sci. pmid:22499865
Saroka JM and Combs GF The lack of effect of a pyridoxine deficiency on the utilization of the hydroxyl analogue of methionine by the chick. 1986 Poult. Sci. pmid:3737508
Zhang JL et al. Different combinations of probiotics improve the production performance, egg quality, and immune response of layer hens. 2012 Poult. Sci. pmid:23091128
Meimandipour A et al. Selected microbial groups and short-chain fatty acids profile in a simulated chicken cecum supplemented with two strains of Lactobacillus. 2010 Poult. Sci. pmid:20181862
Van Immerseel F et al. Microencapsulated short-chain fatty acids in feed modify colonization and invasion early after infection with Salmonella enteritidis in young chickens. 2004 Poult. Sci. pmid:14761086
Cerisuelo A et al. The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. 2014 Poult. Sci. pmid:24604853
Fernández-Rubio C et al. Butyric acid-based feed additives help protect broiler chickens from Salmonella Enteritidis infection. 2009 Poult. Sci. pmid:19359681
Dunkley KD et al. Comparison of in vitro fermentation and molecular microbial profiles of high-fiber feed substrates incubated with chicken cecal inocula. 2007 Poult. Sci. pmid:17435012
Elrod HA and Sun SY PPARgamma and Apoptosis in Cancer. 2008 PPAR Res pmid:18615184
Camps J et al. PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways. 2012 PPAR Res pmid:22315585
Kuniyasu H The Roles of Dietary PPARgamma Ligands for Metastasis in Colorectal Cancer. 2008 PPAR Res pmid:18551182
Carter AB et al. Dietary modulation of inflammation-induced colorectal cancer through PPARγ. 2009 PPAR Res pmid:19390648
Cerbone A et al. AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells. 2012 PPAR Res pmid:22619672
Laundon CH et al. The characterization of hCG regulation in cultured human amniotic fluid cells. 1981 Prenat. Diagn. pmid:7346828
Daniel P et al. [Bladder papilloma. Treatment with interferon, sodium butyrate and isoprinosine]. 1983 Presse Med pmid:6190163
Hirayama T and Ito Y A new view of the etiology of nasopharyngeal carcinoma. 1981 Prev Med pmid:6272265
Walia K et al. Effect of feeding sodium butyrate in the late finishing period on Salmonella carriage, seroprevalence, and growth of finishing pigs. 2016 Prev. Vet. Med. pmid:27544256
Lynch H et al. Investigation of in-feed organic acids as a low cost strategy to combat Salmonella in grower pigs. 2017 Prev. Vet. Med. pmid:28364832
Berezina OV et al. [Extracellular glycosyl hydrolase activity of the clostridia producing acetone, butanol, and ethanol]. 2008 Jan-Feb Prikl. Biokhim. Mikrobiol. pmid:18491597
Pouteau E et al. Production rates and metabolism of short-chain fatty acids in the colon and whole body using stable isotopes. 2003 Proc Nutr Soc pmid:12740063
Macfarlane S and Macfarlane GT Regulation of short-chain fatty acid production. 2003 Proc Nutr Soc pmid:12740060
Hague A et al. The role of butyrate in human colonic epithelial cells: an energy source or inducer of differentiation and apoptosis? 1996 Proc Nutr Soc pmid:9004335
Dronamraju SS et al. Role of DNA-mismatch repair in anti-neoplastic effects of butyrate. 2008 Proc Nutr Soc pmid:18768094
Williams EA et al. Anti-cancer effects of butyrate: use of micro-array technology to investigate mechanisms. 2003 Proc Nutr Soc pmid:12740065
Blottière HM et al. Molecular analysis of the effect of short-chain fatty acids on intestinal cell proliferation. 2003 Proc Nutr Soc pmid:12740064
Bach Knudsen KE et al. New insight into butyrate metabolism. 2003 Proc Nutr Soc pmid:12740062
Delzenne NM Oligosaccharides: state of the art. 2003 Proc Nutr Soc pmid:12749343
Landys MM et al. Metabolic profile of long-distance migratory flight and stopover in a shorebird. 2005 Proc. Biol. Sci. pmid:15705555
Ichikawa A et al. Molecular biology of histidine decarboxylase and prostaglandin receptors. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20948178
Gill RK and Christakos S Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8464915
Ovitt CE et al. Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells. 1986 Proc. Natl. Acad. Sci. U.S.A. pmid:3459156
Barker HA et al. The Synthesis of Butyric and Caproic Acids from Ethanol and Acetic Acid by Clostridium Kluyveri. 1945 Proc. Natl. Acad. Sci. U.S.A. pmid:16588706
Poon AP et al. ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16785443
Rouault TA et al. Influence of altered transcription on the translational control of human ferritin expression. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3476949
Sun R et al. Polyadenylylated nuclear RNA encoded by Kaposi sarcoma-associated herpesvirus. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8876232
Leshin M 5-Azacytidine and sodium butyrate induce expression of aromatase in fibroblasts from chickens carrying the henny feathering trait but not from wild-type chickens. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:2581260
Ohno Y et al. Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9294201
Chen WY et al. Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9159154
Perrine SP et al. Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:2460870
Barratt MJ et al. Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8197135
Asher C and Garty H Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3140240
Takano M et al. Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3186708
Rhoads DB et al. Evidence for expression of the facilitated glucose transporter in rat hepatocytes. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3194405
Klebe RJ et al. Quantitative assay for morphogenesis indicates the role of extracellular matrix components and G proteins. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1658786
Levine A et al. Inhibition of promoter activity by methylation: possible involvement of protein mediators. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1650472
Emiliani S et al. Characterization of a human RPD3 ortholog, HDAC3. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9501169
Archer SY et al. p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9618491
Allis CD et al. Deposition-related histone acetylation in micronuclei of conjugating Tetrahymena. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:3865215
Kessler JA et al. Determination of synaptic phenotype: insulin and cAMP independently initiate development of electrotonic coupling between cultured sympathetic neurons. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6091144
Sharma HW et al. Differentiation of immortal cells inhibits telomerase activity. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:8618897
Bresnick EH et al. Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2160080
O'Shea JJ et al. Expression of v-src in a murine T-cell hybridoma results in constitutive T-cell receptor phosphorylation and interleukin 2 production. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:2000381
Xiong Y et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:14722361
James DE et al. Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2554313
Jansen MS et al. Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15103026
Ginder GD et al. Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6204332
Mason RJ et al. Transepithelial transport by pulmonary alveolar type II cells in primary culture. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6964398
Vaziri ND et al. Effect of experimental azotemia on intestinal transport of butyric acid. 1989 Proc. Soc. Exp. Biol. Med. pmid:2915995
Jacobs LR Relationship between dietary fiber and cancer: metabolic, physiologic, and cellular mechanisms. 1986 Proc. Soc. Exp. Biol. Med. pmid:3025886
Hsu KH and Friedman H Dexamethasone inhibition of DMSO-induced transglutaminase activity and differentiation of leukemic cells. 1984 Proc. Soc. Exp. Biol. Med. pmid:6141568
VISSCHER FE Renal clearance of beta-hydroxybutyric acid in a dog. 1945 Proc. Soc. Exp. Biol. Med. pmid:21006321
Yen A and Chandler S Inducers of leukemic cell differentiation cause down-regulation of RB gene expression. 1992 Proc. Soc. Exp. Biol. Med. pmid:1539032
Basson MD et al. Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids. 1998 Proc. Soc. Exp. Biol. Med. pmid:9521097
LACKEY RW et al. Effect on cardiac glycogen of intravenously administered sodium acetoacetate, sodium beta-hydroxybutyrate and sodium butyrate. 1947 Proc. Soc. Exp. Biol. Med. pmid:18921782
Tralka TS et al. Sodium n-butyrate causes reversible decrease in condensed chromatin clumps in HeLa cells. 1979 Proc. Soc. Exp. Biol. Med. pmid:482289
Tralka TS et al. Butyrate increases type-A and type-R virus-like particles in BKV-transformed hamster spleen cells. 1983 Proc. Soc. Exp. Biol. Med. pmid:6314342
TRAVERS JJ and CERECEDO LR Effects of methoxinine in the mouse. 1951 Proc. Soc. Exp. Biol. Med. pmid:14844253
Ginder GD et al. Transcriptional activation of an embryonic globin gene in adult erythroid cells in vivo. 1985 Prog. Clin. Biol. Res. pmid:2413482
Roettger V et al. Multiple acyl-coenzyme A dehydrogenation disorders (MAD) responsive to riboflavin: biochemical studies in fibroblasts. 1992 Prog. Clin. Biol. Res. pmid:1438377
Coscia CJ et al. Effects of up-regulation by butyrate on delta opioid receptor GTP sensitivity and distribution in subcellular compartments. 1990 Prog. Clin. Biol. Res. pmid:2154771
Constantoulakis P et al. Butyrate stimulates HbF in adult baboons. 1989 Prog. Clin. Biol. Res. pmid:2482502
Chou JY and Ito F Regulation of alkaline phosphatase gene expression in cultured placental cells. 1984 Prog. Clin. Biol. Res. pmid:6542217
Kam WK et al. The expression of alkaline phosphatases in human gastrointestinal and pancreatic tissues and cell lines. 1984 Prog. Clin. Biol. Res. pmid:6504927
Holtzer H et al. Induction-dependent and lineage-dependent models for cell diversification are mutually exclusive. 1985 Prog. Clin. Biol. Res. pmid:3991734
Iavarone A et al. 3-D changes in neuroblastoma x glioma hybrid (NG 108-15) cell differentiation as studied by SEM and TEM. 1989 Prog. Clin. Biol. Res. pmid:2546164
Rowley PT and Ohlsson-Wilhelm BM Demonstration of commitment by K562 human erythroleukemia cells. 1985 Prog. Clin. Biol. Res. pmid:3863148
Perrine SP et al. Butyrate analogues modulate globin gene expression in human and ovine erythroid cells. 1989 Prog. Clin. Biol. Res. pmid:2616579
Lass A et al. Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. 2011 Prog. Lipid Res. pmid:21087632
Koener B et al. Increasing the density of the D2L receptor and manipulating the receptor environment are required to evidence the partial agonist properties of aripiprazole. 2012 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:21871520
Wang CC et al. Valproic acid mediates the synaptic excitatory/inhibitory balance through astrocytes--a preliminary study. 2012 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:22343008
Kawamura M et al. Enhancement of prostaglandin synthesizing activity by the treatment with sodium n-butyrate on cloned mastocytoma cells and various other tissue cell lines. 1980 Prostaglandins pmid:6775349
Awad AB et al. Prostaglandin synthesis in human cancer cells: influence of fatty acids and butyrate. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7480078
Hsi LC et al. Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418015