butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Lymphoma, AIDS-Related D016483 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Dementia, Vascular D015140 7 associated lipids
Hemorrhoids D006484 2 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Medina V et al. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. 1997 Cancer Res. pmid:9288776
Talley NA et al. Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial. 1997 Dis. Colon Rectum pmid:9293933
Ohno Y et al. Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9294201
Lewis SJ and Heaton KW Increasing butyrate concentration in the distal colon by accelerating intestinal transit. 1997 Gut pmid:9301506
Chénais B et al. Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels. 1997 Leukemia pmid:9305615
Cuisset L et al. The effects of sodium butyrate on transcription are mediated through activation of a protein phosphatase. 1997 J. Biol. Chem. pmid:9305863
Birkett AM et al. Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. 1997 Eur J Clin Nutr pmid:9306090
Ishiguro K and Sartorelli AC Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin. 1997 Blood pmid:9310478
Hague A et al. bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. 1997 Int. J. Cancer pmid:9311611
Dohi H et al. Intake stimulants in perennial ryegrass (Lolium perenne L.) fed to sheep. 1997 J. Dairy Sci. pmid:9313150
Engelhard HH et al. Molecular characterization of glioblastoma cell differentiation. 1997 Neurosurgery pmid:9316051
Scannell JP et al. Antimetabolites produced by microorganisms. XIII. The synthesis and microbiological production of a novel amino acid, L-2-amino-4-(2-aminoethoxy) butanoic acid. 1976 J. Antibiot. pmid:931793
Kaiser E and Weiss K [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. 1997 Arch Tierernahr pmid:9324922
Janson W et al. Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis. 1997 Oncogene pmid:9333015
Sovová V et al. Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines. 1997 Folia Biol. (Praha) pmid:9338115
Garcia-Bermejo L et al. Modulation of heat-shock protein 70 (HSP70) gene expression by sodium butyrate in U-937 promonocytic cells: relationships with differentiation and apoptosis. 1997 Exp. Cell Res. pmid:9344607
Vecchia MG et al. Acetate and propionate potentiate the antiproliferative effect of butyrate on RBL-2H3 growth. 1997 Gen. Pharmacol. pmid:9347317
Loukopoulos D New therapies for the haemoglobinopathies. 1997 J Intern Med Suppl pmid:9350181
Kavaliers M et al. Opioid and non-opioid NMDA-mediated predator-induced analgesia in mice and the effects of parasitic infection. 1997 Brain Res. pmid:9359582
O'Mara FP et al. Rumen fermentation and nutrient flows for cows fed grass and grass supplemented with molassed beet pulp pellets. 1997 J. Dairy Sci. pmid:9361218
Barnard JA et al. Short chain fatty acid regulation of intestinal gene expression. 1997 Adv. Exp. Med. Biol. pmid:9361821
Velázquez OC et al. Butyrate and the colonocyte. Production, absorption, metabolism, and therapeutic implications. 1997 Adv. Exp. Med. Biol. pmid:9361838
Velázquez OC and Rombeau JL Butyrate. Potential role in colon cancer prevention and treatment. 1997 Adv. Exp. Med. Biol. pmid:9361842
Singh M Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro. 1979 J. Physiol. (Lond.) pmid:93637
Payne KL et al. Modulation of T3-induced sex hormone-binding globulin secretion by human hepatoblastoma cells. 1997 Eur. J. Endocrinol. pmid:9368511
Velázquez OC et al. Butyrate inhibits deoxycholate-induced increase in colonic mucosal DNA and protein synthesis in vivo. 1997 Dis. Colon Rectum pmid:9369115
Kolesnitchenko V et al. A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis. 1997 J. Virol. pmid:9371641
Faller DV and Perrine SP Butyrate in the treatment of sickle cell disease and beta-thalassemia. 1995 Curr. Opin. Hematol. pmid:9371980
Coradini D et al. Effect of sodium butyrate on human breast cancer cell lines. 1997 Mar-Apr Cell Prolif. pmid:9375027
Onaga T et al. Effect of pituitary adenylate cyclase-activating polypeptide on exocrine and endocrine secretion in the ovine pancreas. 1996 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9375356
Hassig CA et al. Fiber-derived butyrate and the prevention of colon cancer. 1997 Chem. Biol. pmid:9384528
Vimard C et al. Changes in the sedimentation properties of acetycholinesterase during neuroblastoma differentiation. 1976 Biochimie pmid:938691
Palmer DG et al. Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. 1997 Int. J. Cancer pmid:9398049
Cordel S et al. 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. 1997 Int. J. Cancer pmid:9399677
Moore JW et al. Thiolmethyltransferase activity in the human colonic mucosa: implications for ulcerative colitis. 1997 J. Gastroenterol. Hepatol. pmid:9407333
Böhmig GA et al. n-butyrate downregulates the stimulatory function of peripheral blood-derived antigen-presenting cells: a potential mechanism for modulating T-cell responses by short-chain fatty acids. 1997 Immunology pmid:9415032
Callus BA et al. Haemoglobin synthesis in erythropoietin-stimulated J2E cells does not require increased numbers of transferrin receptors. 1997 Eur. J. Biochem. pmid:9428699
Yabushita H et al. Emergence of an irreversible differentiated subclone from the poorly differentiated ovarian adenocarcinoma cell line AMOC-2 treated with sodium butyrate. 1997 J. Obstet. Gynaecol. Res. pmid:9433040
Ono M et al. Resin glycosides. XXV. Multifidins I and II, new jalapins, from the seed of Quamoclit x multifida. 1997 Chem. Pharm. Bull. pmid:9433765
Medina V et al. Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer. 1998 Jan-Feb JPEN J Parenter Enteral Nutr pmid:9437648
Gupta KP and Mehrotra NK Differential effects of butyric acid on mouse skin tumorigenesis. 1997 Biomed. Environ. Sci. pmid:9448925
Perez-Esteban J et al. Lipase activity of Pseudomonas fluorescens in cold raw skim milk with different lipid supplements. 1997 Folia Microbiol. (Praha) pmid:9449781
Leber BF and Denburg JA Retinoic acid modulation of induced basophil differentiation. 1997 Allergy pmid:9450139
Saleh AW and Hillen HF Pharmacological induction of foetal haemoglobin synthesis in sickle-cell disease. 1997 Neth J Med pmid:9455096
Llorente A et al. Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus. 1998 J. Cell Biol. pmid:9456316
Gillenwater A et al. Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate. 1998 Int. J. Cancer pmid:9462711
Shimizu A et al. CyclinG contributes to G2/M arrest of cells in response to DNA damage. 1998 Biochem. Biophys. Res. Commun. pmid:9464250
Yamane M et al. Docosahexaenoic/arachidonic acid omega-hydroxylation system and differentiation in the human colonic adenocarcinoma cell line, Caco-2. 1998 Cancer Lett. pmid:9464491
Yamamoto I et al. Interleukin-2-dependent augmentation of the anti-TNP antibody production by sodium butyrate in cultured murine splenic B cells. 1997 Int. J. Immunopharmacol. pmid:9467754
Dong-Le Bourhis X et al. Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells. 1998 Br. J. Cancer pmid:9472634
Umenishi F and Verkman AS Isolation of the human aquaporin-1 promoter and functional characterization in human erythroleukemia cell lines. 1998 Genomics pmid:9480747
Dumas D et al. Effect of glutaraldehyde on hemoglobin-dependent quenching of pyrene fluorescence. Application to oxygen diffusion in erythrocyte. 1997 Jul-Aug Clin. Hemorheol. Microcirc. pmid:9493896
Lawrence C and Grossman R Simple butyrate esterase stain for monocytes. 1979 Stain Technol pmid:94951
Emiliani S et al. Characterization of a human RPD3 ortholog, HDAC3. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9501169
Ritzhaupt A et al. The characterization of butyrate transport across pig and human colonic luminal membrane. 1998 J. Physiol. (Lond.) pmid:9508842
Moore-Hoon ML and Turner RJ Increased expression of the secretory Na+-K+-2Cl- cotransporter with differentiation of a human intestinal cell line. 1998 Biochem. Biophys. Res. Commun. pmid:9514875
Basson MD et al. Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids. 1998 Proc. Soc. Exp. Biol. Med. pmid:9521097
Nathan I et al. Alterations in membrane lipid dynamics of leukemic cells undergoing growth arrest and differentiation: dependency on the inducing agent. 1998 Exp. Cell Res. pmid:9521862
Johnstone RM et al. Loss of glucose transport in developing avian red cells. 1998 Eur. J. Cell Biol. pmid:9523157
Charney AN et al. Nonionic diffusion of short-chain fatty acids across rat colon. 1998 Am. J. Physiol. pmid:9530153
Komatsu Y and Hayashi H Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells. 1998 J. Antibiot. pmid:9531994
Kondo A et al. Detection of antitumor promoting activity in Raji cells carrying Epstein-Barr virus genome by immunoblotting analysis. 1998 Biosci. Biotechnol. Biochem. pmid:9532799
Giardina C and Inan MS Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells. 1998 Biochim. Biophys. Acta pmid:9540818
Hasegawa S et al. Sickling of nucleated erythroid precursors from patients with sickle cell anemia. 1998 Exp. Hematol. pmid:9546314
Barka T Effect of sodium butyrate on the expression of genes transduced by retroviral vectors. 1998 J. Cell. Biochem. pmid:9548567
Krishnan S et al. The ability of enteric diarrhoeal pathogens to ferment starch to short-chain fatty acids in vitro. 1998 Scand. J. Gastroenterol. pmid:9548615
Krishnan S and Ramakrishna BS Butyrate and glucose metabolism in isolated colonocytes in the developing rat colon. 1998 J. Pediatr. Gastroenterol. Nutr. pmid:9552140
Yabuuchi H et al. Possible role of anion exchanger AE2 as the intestinal monocarboxylic acid/anion antiporter. 1998 Pharm. Res. pmid:9563070
Krebsfänger N et al. Enantioselectivity of a recombinant esterase from Pseudomonas fluorescens towards alcohols and carboxylic acids. 1998 J. Biotechnol. pmid:9571805
Kondo K et al. Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines. 1998 Cancer Res. pmid:9581847
Zhang M et al. Heat-induced proteolysis of HSF causes premature deactivation of the heat shock response in Nb2 lymphoma cells. 1998 Cell Stress Chaperones pmid:9585182
Clark PR et al. A novel drug screening assay for papillomavirus specific antiviral activity. 1998 Antiviral Res. pmid:9588842
Fukushima K et al. Sodium butyrate-induced liver-type alkaline phosphatase activity in a small intestinal epithelial cell line, IEC6. 1998 Dig. Dis. Sci. pmid:9590430
Matthews JB et al. Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate. 1998 J. Clin. Invest. pmid:9593763
Walia H et al. Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA. 1998 J. Biol. Chem. pmid:9603965
Cuisset L et al. A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate. 1998 Biochem. Biophys. Res. Commun. pmid:9618285
Archer SY et al. p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9618491
Perez RV et al. Selective targeting of Kupffer cells with liposomal butyrate augments portal venous transfusion-induced immunosuppression. 1998 Transplantation pmid:9625008
Yamamoto H et al. Suppression of growth of hepatocellular carcinoma by sodium butyrate in vitro and in vivo. 1998 Int. J. Cancer pmid:9626359
Smith JG et al. Butyric acid from the diet: actions at the level of gene expression. 1998 Crit Rev Food Sci Nutr pmid:9626487
Tsumura H et al. Mouse alloantigen Ly10 is identical to murine fusion regulatory protein-1 (mFRP-1)/4F2/CD98: aberrant expression of mFRP-1/Ly10 allotypes in cells derived from CDF1 mice due to the gene deletion. 1998 Cell. Immunol. pmid:9630841
Caderni G et al. Slow-release pellets of sodium butyrate increase apoptosis in the colon of rats treated with azoxymethane, without affecting aberrant crypt foci and colonic proliferation. 1998 Nutr Cancer pmid:9631487
Santini V et al. Butyrate-stable monosaccharide derivatives induce maturation and apoptosis in human acute myeloid leukaemia cells. 1998 Br. J. Haematol. pmid:9633898
Wang XM et al. Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. 1998 Ann. Surg. pmid:9637556
George CH et al. Rapid determination of gap junction formation using HeLa cells microinjected with cDNAs encoding wild-type and chimeric connexins. 1998 Biochem. Biophys. Res. Commun. pmid:9647771
Dangond F and Gullans SR Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate. 1998 Biochem. Biophys. Res. Commun. pmid:9647779
Morita T et al. Resistant proteins alter cecal short-chain fatty acid profiles in rats fed high amylose cornstarch. 1998 J. Nutr. pmid:9649600
Heerdt BG et al. Mitochondrial membrane potential (delta psi(mt)) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells. 1998 Cancer Res. pmid:9661904
Vaziri C et al. Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals. 1998 Cell Growth Differ. pmid:9663465
Taimi M et al. Potentiation of retinoic acid-induced differentiation of human acute promyelocytic leukemia NB4 cells by butyric acid, tributyrin, and hexamethylene bisacetamide. 1998 Oncol. Res. pmid:9666515
Jacobs HC et al. Fetal lung mRNA levels of Hox genes are differentially altered by maternal diabetes and butyrate in rats. 1998 Pediatr. Res. pmid:9667378
Itoh F et al. Effects of heat exposure on plasma insulin, glucagon and metabolites in response to nutrient injection in heifers. 1998 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9669085
Zhang J et al. Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen. 1998 J. Nutr. pmid:9687542
Nishimura A et al. Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells. 1998 Am. J. Physiol. pmid:9688874
Holtbäck U et al. Neuropeptide Y shifts equilibrium between alpha- and beta-adrenergic tonus in proximal tubule cells. 1998 Am. J. Physiol. pmid:9688998
von Engelhardt W et al. Role of short-chain fatty acids in the hind gut. 1998 Vet Q pmid:9689727
Nakano K et al. [A novel approach for cancer chemoprevention referred to as "gene-regulating chemoprevention"]. 1998 Nihon Geka Gakkai Zasshi pmid:9695075
Lauricella M et al. Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells. 1998 Tumour Biol. pmid:9701726
Davletshin AI et al. [Effect of surfactants on peroxidase activity. I. Effect of anionic surfactants]. 1998 Bioorg. Khim. pmid:9702352
Lea MA and Randolph VM Induction of reporter gene expression by inhibitors of histone deacetylase. 1998 Jul-Aug Anticancer Res. pmid:9703934