butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Gubicza L et al. | Large-scale enzymatic production of natural flavour esters in organic solvent with continuous water removal. | 2001 | J. Biotechnol. | pmid:11090691 |
Maeda T et al. | Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells. | 2000 | Blood | pmid:11090069 |
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pmid:11071567 | ||||
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Sadar MD and Gleave ME | Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells. | 2000 | Cancer Res. | pmid:11059779 |
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Mroz Z et al. | The effects of calcium benzoate in diets with or without organic acids on dietary buffering capacity, apparent digestibility, retention of nutrients, and manure characteristics in swine. | 2000 | J. Anim. Sci. | pmid:11048928 |
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Cox GS | Cellular responses to sodium butyrate exhibit the dominance of one parental phenotype in somatic cell hybrids. | 2000 | Mol. Cell Biol. Res. Commun. | pmid:11032754 |
Hezayen FF et al. | Polymer production by two newly isolated extremely halophilic archaea: application of a novel corrosion-resistant bioreactor. | 2000 | Appl. Microbiol. Biotechnol. | pmid:11030566 |
Leschelle X et al. | Butyrate metabolism upstream and downstream acetyl-CoA synthesis and growth control of human colon carcinoma cells. | 2000 | Eur. J. Biochem. | pmid:11029587 |
Désilets A et al. | Inhibition by deacetylase inhibitors of IL-1-dependent induction of haptoglobin involves CCAAT/Enhancer-binding protein isoforms in intestinal epithelial cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11027530 |
Schröder O et al. | Substrate and inhibitor specificity of butyrate uptake in apical membrane vesicles of the rat distal colon. | 2000 | Digestion | pmid:11025362 |
Säemann MD et al. | Anti-inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL-12 and up-regulation of IL-10 production. | 2000 | FASEB J. | pmid:11024006 |
Murphy JP et al. | Histone deacetylase inhibitors and cell proliferation in pea root meristems. | 2000 | Phytochemistry | pmid:11021638 |
Hirayama F et al. | Release characteristics of a short-chain fatty acid, n-butyric acid, from its beta-cyclodextrin ester conjugate in rat biological media. | 2000 | J Pharm Sci | pmid:11015693 |
Evdokiou A et al. | Identification of a novel calcitonin-response element in the promoter of the human p21WAF1/CIP1 gene. | 2000 | J. Mol. Endocrinol. | pmid:11013346 |
Le Blay G et al. | Short-chain fatty acids induce cytoskeletal and extracellular protein modifications associated with modulation of proliferation on primary culture of rat intestinal smooth muscle cells. | 2000 | Dig. Dis. Sci. | pmid:11007115 |
Lauricella M et al. | Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells. | 2000 Nov-Dec | Tumour Biol. | pmid:11006574 |
Shie JL et al. | Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11005769 |
Maier S et al. | Tributyrin induces differentiation, growth arrest and apoptosis in androgen-sensitive and androgen-resistant human prostate cancer cell lines. | 2000 | Int. J. Cancer | pmid:11004676 |
Karlsson S et al. | Toxins, butyric acid, and other short-chain fatty acids are coordinately expressed and down-regulated by cysteine in Clostridium difficile. | 2000 | Infect. Immun. | pmid:10992498 |
Kano K et al. | Complexation of polyvalent cyclodextrin ions with oppositely charged guests: entropically favorable complexation due to dehydration. | 2000 | Chemistry | pmid:10985719 |
Xie P et al. | Nerve growth factor potentiated the sodium butyrate- and PMA-induced megakaryocytic differentiation of K562 leukemia cells. | 2000 | Leuk. Res. | pmid:10978779 |
Weinmann W et al. | Simultaneous determination of THC-COOH and THC-COOH-glucuronide in urine samples by LC/MS/MS. | 2000 | Forensic Sci. Int. | pmid:10978652 |
Pedersen G et al. | Cytokine-induced impairment of short-chain fatty acid oxidation and viability in human colonic epithelial cells. | 2000 | Cytokine | pmid:10976002 |
KovarÃková M et al. | TNF-alpha modulates the differentiation induced by butyrate in the HT-29 human colon adenocarcinoma cell line. | 2000 | Eur. J. Cancer | pmid:10974633 |
Pedersen G et al. | A simple method to establish short-term cultures of normal human colonic epithelial cells from endoscopic biopsy specimens. Comparison of isolation methods, assessment of viability and metabolic activity. | 2000 | Scand. J. Gastroenterol. | pmid:10972184 |
Mariadason JM et al. | Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. | 2000 | Cancer Res. | pmid:10969808 |
Salah AM et al. | In vitro purgative effect of Ruellia praetermissa. Sceinf.ex.Lindau (Acanthaceae). | 2000 | J Ethnopharmacol | pmid:10967480 |
Hsu CP et al. | Suppression of proline-directed protein kinase F(A) expression potentiates erythroid differentiation of human myeloid leukemia cells. | 2000 | Cancer | pmid:10964330 |
Birkett AM et al. | Changes to the quantity and processing of starchy foods in a western diet can increase polysaccharides escaping digestion and improve in vitro fermentation variables. | 2000 | Br. J. Nutr. | pmid:10961162 |
Wolever TM and Chiasson JL | Acarbose raises serum butyrate in human subjects with impaired glucose tolerance. | 2000 | Br. J. Nutr. | pmid:10961161 |
Wisker E et al. | Short-chain fatty acids produced in vitro from fibre residues obtained from mixed diets containing different breads and in human faeces during the ingestion of the diets. | 2000 | Br. J. Nutr. | pmid:10961158 |
Garjani A et al. | Effects of extracts from flowering tops of Crataegus meyeri A. Pojark. on ischaemic arrhythmias in anaesthetized rats. | 2000 | Phytother Res | pmid:10960896 |
Coradini D et al. | Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells. | 2000 | Cell Prolif. | pmid:10959623 |
Nudelman A and Rephaeli A | Novel mutual prodrug of retinoic and butyric acids with enhanced anticancer activity. | 2000 | J. Med. Chem. | pmid:10956204 |
Gostner A et al. | Comparisons of the anti-proliferative effects of butyrate and aspirin on human colonic mucosa in vitro. | 2000 | Eur. J. Cancer Prev. | pmid:10954260 |
Tsai LC et al. | Apoptosis induced by the sodium butyrate in human gastric cancer TMK-1 cells. | 2000 Jul-Aug | Anticancer Res. | pmid:10953308 |
Rooman I et al. | Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. | 2000 | Diabetologia | pmid:10952464 |
Oufir LE et al. | Relationships between transit time in man and in vitro fermentation of dietary fiber by fecal bacteria. | 2000 | Eur J Clin Nutr | pmid:10951507 |
Masuda T et al. | Up-regulation of E-cadherin and I-catenin in human hepatocellular carcinoma cell lines by sodium butyrate and interferon-alpha. | 2000 | In Vitro Cell. Dev. Biol. Anim. | pmid:10949998 |
Shadan FF and Villarreal LP | n-Butyrate mediated inhibition of papovavirus DNA replication in vivo and in cell culture: a mechanistic approach. | 2000 | Virus Genes | pmid:10949947 |
Jensen UB et al. | Transgene expression in human epidermal keratinocytes: cell cycle arrest of productively transfected cells. | 2000 | Exp. Dermatol. | pmid:10949553 |
Mboera LE et al. | The response of Culex quinquefasciatus (Diptera: culicidae) to traps baited with carbon dioxide, 1-octen-3-ol, acetone, butyric acid and human foot odour in Tanzania. | 2000 | Bull. Entomol. Res. | pmid:10948375 |
Gilbert KM et al. | Potential clinical use of butyric acid derivatives to induce antigen-specific T cell inactivation. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945871 |
Marilley D and Schwaller B | Association between the calcium-binding protein calretinin and cytoskeletal components in the human colon adenocarcinoma cell line WiDr. | 2000 | Exp. Cell Res. | pmid:10942575 |
Koyama Y et al. | Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis. | 2000 | Blood | pmid:10942396 |
Andersen DC et al. | Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator. | 2000 | Biotechnol. Bioeng. | pmid:10940860 |
Sanderson IR and Naik S | Dietary regulation of intestinal gene expression. | 2000 | Annu. Rev. Nutr. | pmid:10940337 |
Segain JP et al. | Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. | 2000 | Gut | pmid:10940278 |
Matthies C et al. | Anaerovorax odorimutans gen. nov., sp. nov., a putrescine-fermenting, strictly anaerobic bacterium. | 2000 | Int. J. Syst. Evol. Microbiol. | pmid:10939665 |
Zelivianski S et al. | Expression of receptor protein tyrosine phosphatase alpha mRNA in human prostate cancer cell lines. | 2000 | Mol. Cell. Biochem. | pmid:10939623 |
Parrer G et al. | Conversion of solvent evaporation residues from the AB- (acetone-butanol) bioprocess into bacterial cells accumulating thermoplastic polyesters. | 2000 | J. Mol. Microbiol. Biotechnol. | pmid:10939239 |
Magee RM et al. | Synthesis of osteonectin by human retinal pigment epithelial cells is modulated by cell density. | 2000 | Invest. Ophthalmol. Vis. Sci. | pmid:10937587 |
Parrer G et al. | Conversion of solvent evaporation residues from the AB- (acetone - butanol) bioprocess into bacterial cells accumulating thermoplastic polyesters. | 2000 | J. Mol. Microbiol. Biotechnol. | pmid:10937491 |
Huang KX et al. | Identification and characterization of a second butyrate kinase from Clostridium acetobutylicum ATCC 824. | 2000 | J. Mol. Microbiol. Biotechnol. | pmid:10937485 |
Müller F et al. | Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen. | 2000 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:10935525 |
Lawson PA et al. | New LL-diaminopimelic acid-containing actinomycetes from hypersaline, heliothermal and meromictic Antarctic Ekho Lake: Nocardioides aquaticus sp. nov. and Friedmanniella [correction of Friedmannielly] lacustris sp. nov. | 2000 | Syst. Appl. Microbiol. | pmid:10930074 |
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Haas MJ et al. | Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones. | 2000 | J. Mol. Endocrinol. | pmid:10915225 |
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Witt O et al. | Tributyrin plus all-trans-retinoic acid efficiently induces fetal hemoglobin expression in human erythroleukemia cells. | 2000 | Am. J. Hematol. | pmid:10911389 |
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Peinnequin A et al. | Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line. | 2000 | Bioelectrochemistry | pmid:10910164 |
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Lupton JR | Is fiber protective against colon cancer? Where the research is leading us. | 2000 Jul-Aug | Nutrition | pmid:10906555 |
Bai L and Merchant JL | Transcription factor ZBP-89 cooperates with histone acetyltransferase p300 during butyrate activation of p21waf1 transcription in human cells. | 2000 | J. Biol. Chem. | pmid:10899165 |
Karlsson A et al. | CO2-dependent fermentation of phenol to acetate, butyrate and benzoate by an anaerobic, pasteurised culture. | 2000 May-Jun | Arch. Microbiol. | pmid:10896220 |
Wu YD and Song JD | The expression of glucose regulated protein-94 in colorectal carcinoma cells treated by sodium butyrate. | 2000 | Cell Res. | pmid:10896173 |
Ferguson LR et al. | Comparative effects of three resistant starch preparations on transit time and short-chain fatty acid production in rats. | 2000 | Nutr Cancer | pmid:10890035 |
Belobrajdic DP and McIntosh GH | Dietary butyrate inhibits NMU-induced mammary cancer in rats. | 2000 | Nutr Cancer | pmid:10890033 |
Olano-Martin E et al. | In vitro fermentability of dextran, oligodextran and maltodextrin by human gut bacteria. | 2000 | Br. J. Nutr. | pmid:10884713 |
Takahashi M et al. | Studies of the effect of Clostridium butyricum on Helicobacter pylori in several test models including gnotobiotic mice. | 2000 | J. Med. Microbiol. | pmid:10882089 |
McMillan L et al. | Bile acids reduce the apoptosis-inducing effects of sodium butyrate on human colon adenoma (AA/C1) cells: implications for colon carcinogenesis. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10873561 |
Wilson AJ and Gibson PR | Role of urokinase and its receptor in basal and stimulated colonic epithelial cell migration in vitro. | 2000 | Gut | pmid:10861271 |
Bonge H et al. | Cytostar-T scintillating microplate assay for measurement of sodium-dependent bile acid uptake in transfected HEK-293 cells. | 2000 | Anal. Biochem. | pmid:10860504 |
Segouffin-Cariou C et al. | Characterization of the epstein-barr virus BRRF1 gene, located between early genes BZLF1 and BRLF1. | 2000 | J. Gen. Virol. | pmid:10859385 |
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Andoh A et al. | Modulation of complement component (C3 and factor B) biosynthesis by a histone deacetylase inhibitor in human intestinal epithelial cells. | 2000 | Int. J. Mol. Med. | pmid:10851266 |