butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Psychophysiologic Disorders D011602 3 associated lipids
Radiation Injuries D011832 14 associated lipids
Retinoblastoma D012175 12 associated lipids
Retroviridae Infections D012192 4 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Sarcoma 180 D012510 21 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Osteosarcoma D012516 50 associated lipids
Seizures D012640 87 associated lipids
Starvation D013217 47 associated lipids
Thalassemia D013789 8 associated lipids
Thrombosis D013927 49 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Uremia D014511 33 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Dementia, Vascular D015140 7 associated lipids
Gastrinoma D015408 1 associated lipids
Weight Gain D015430 101 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
HIV Infections D015658 20 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Strongylida Infections D017206 5 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Hepatoblastoma D018197 10 associated lipids
Teratocarcinoma D018243 7 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Multiple Chemical Sensitivity D018777 4 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Pouchitis D019449 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Genomic Instability D042822 7 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Umenishi F and Verkman AS Isolation of the human aquaporin-1 promoter and functional characterization in human erythroleukemia cell lines. 1998 Genomics pmid:9480747
Dumas D et al. Effect of glutaraldehyde on hemoglobin-dependent quenching of pyrene fluorescence. Application to oxygen diffusion in erythrocyte. 1997 Jul-Aug Clin. Hemorheol. Microcirc. pmid:9493896
Lawrence C and Grossman R Simple butyrate esterase stain for monocytes. 1979 Stain Technol pmid:94951
Emiliani S et al. Characterization of a human RPD3 ortholog, HDAC3. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9501169
Ritzhaupt A et al. The characterization of butyrate transport across pig and human colonic luminal membrane. 1998 J. Physiol. (Lond.) pmid:9508842
Moore-Hoon ML and Turner RJ Increased expression of the secretory Na+-K+-2Cl- cotransporter with differentiation of a human intestinal cell line. 1998 Biochem. Biophys. Res. Commun. pmid:9514875
Basson MD et al. Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids. 1998 Proc. Soc. Exp. Biol. Med. pmid:9521097
Nathan I et al. Alterations in membrane lipid dynamics of leukemic cells undergoing growth arrest and differentiation: dependency on the inducing agent. 1998 Exp. Cell Res. pmid:9521862
Johnstone RM et al. Loss of glucose transport in developing avian red cells. 1998 Eur. J. Cell Biol. pmid:9523157
Charney AN et al. Nonionic diffusion of short-chain fatty acids across rat colon. 1998 Am. J. Physiol. pmid:9530153
Komatsu Y and Hayashi H Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells. 1998 J. Antibiot. pmid:9531994
Kondo A et al. Detection of antitumor promoting activity in Raji cells carrying Epstein-Barr virus genome by immunoblotting analysis. 1998 Biosci. Biotechnol. Biochem. pmid:9532799
Giardina C and Inan MS Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells. 1998 Biochim. Biophys. Acta pmid:9540818
Hasegawa S et al. Sickling of nucleated erythroid precursors from patients with sickle cell anemia. 1998 Exp. Hematol. pmid:9546314
Barka T Effect of sodium butyrate on the expression of genes transduced by retroviral vectors. 1998 J. Cell. Biochem. pmid:9548567
Krishnan S et al. The ability of enteric diarrhoeal pathogens to ferment starch to short-chain fatty acids in vitro. 1998 Scand. J. Gastroenterol. pmid:9548615
Krishnan S and Ramakrishna BS Butyrate and glucose metabolism in isolated colonocytes in the developing rat colon. 1998 J. Pediatr. Gastroenterol. Nutr. pmid:9552140
Yabuuchi H et al. Possible role of anion exchanger AE2 as the intestinal monocarboxylic acid/anion antiporter. 1998 Pharm. Res. pmid:9563070
Krebsfänger N et al. Enantioselectivity of a recombinant esterase from Pseudomonas fluorescens towards alcohols and carboxylic acids. 1998 J. Biotechnol. pmid:9571805
Kondo K et al. Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines. 1998 Cancer Res. pmid:9581847
Zhang M et al. Heat-induced proteolysis of HSF causes premature deactivation of the heat shock response in Nb2 lymphoma cells. 1998 Cell Stress Chaperones pmid:9585182
Clark PR et al. A novel drug screening assay for papillomavirus specific antiviral activity. 1998 Antiviral Res. pmid:9588842
Fukushima K et al. Sodium butyrate-induced liver-type alkaline phosphatase activity in a small intestinal epithelial cell line, IEC6. 1998 Dig. Dis. Sci. pmid:9590430
Matthews JB et al. Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate. 1998 J. Clin. Invest. pmid:9593763
Walia H et al. Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA. 1998 J. Biol. Chem. pmid:9603965
Cuisset L et al. A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate. 1998 Biochem. Biophys. Res. Commun. pmid:9618285
Archer SY et al. p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9618491
Perez RV et al. Selective targeting of Kupffer cells with liposomal butyrate augments portal venous transfusion-induced immunosuppression. 1998 Transplantation pmid:9625008
Yamamoto H et al. Suppression of growth of hepatocellular carcinoma by sodium butyrate in vitro and in vivo. 1998 Int. J. Cancer pmid:9626359
Smith JG et al. Butyric acid from the diet: actions at the level of gene expression. 1998 Crit Rev Food Sci Nutr pmid:9626487
Tsumura H et al. Mouse alloantigen Ly10 is identical to murine fusion regulatory protein-1 (mFRP-1)/4F2/CD98: aberrant expression of mFRP-1/Ly10 allotypes in cells derived from CDF1 mice due to the gene deletion. 1998 Cell. Immunol. pmid:9630841
Caderni G et al. Slow-release pellets of sodium butyrate increase apoptosis in the colon of rats treated with azoxymethane, without affecting aberrant crypt foci and colonic proliferation. 1998 Nutr Cancer pmid:9631487
Santini V et al. Butyrate-stable monosaccharide derivatives induce maturation and apoptosis in human acute myeloid leukaemia cells. 1998 Br. J. Haematol. pmid:9633898
Wang XM et al. Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. 1998 Ann. Surg. pmid:9637556
George CH et al. Rapid determination of gap junction formation using HeLa cells microinjected with cDNAs encoding wild-type and chimeric connexins. 1998 Biochem. Biophys. Res. Commun. pmid:9647771
Dangond F and Gullans SR Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate. 1998 Biochem. Biophys. Res. Commun. pmid:9647779
Morita T et al. Resistant proteins alter cecal short-chain fatty acid profiles in rats fed high amylose cornstarch. 1998 J. Nutr. pmid:9649600
Heerdt BG et al. Mitochondrial membrane potential (delta psi(mt)) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells. 1998 Cancer Res. pmid:9661904
Vaziri C et al. Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals. 1998 Cell Growth Differ. pmid:9663465
Taimi M et al. Potentiation of retinoic acid-induced differentiation of human acute promyelocytic leukemia NB4 cells by butyric acid, tributyrin, and hexamethylene bisacetamide. 1998 Oncol. Res. pmid:9666515
Jacobs HC et al. Fetal lung mRNA levels of Hox genes are differentially altered by maternal diabetes and butyrate in rats. 1998 Pediatr. Res. pmid:9667378
Itoh F et al. Effects of heat exposure on plasma insulin, glucagon and metabolites in response to nutrient injection in heifers. 1998 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9669085
Zhang J et al. Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen. 1998 J. Nutr. pmid:9687542
Nishimura A et al. Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells. 1998 Am. J. Physiol. pmid:9688874
Holtbäck U et al. Neuropeptide Y shifts equilibrium between alpha- and beta-adrenergic tonus in proximal tubule cells. 1998 Am. J. Physiol. pmid:9688998
von Engelhardt W et al. Role of short-chain fatty acids in the hind gut. 1998 Vet Q pmid:9689727
Nakano K et al. [A novel approach for cancer chemoprevention referred to as "gene-regulating chemoprevention"]. 1998 Nihon Geka Gakkai Zasshi pmid:9695075
Lauricella M et al. Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells. 1998 Tumour Biol. pmid:9701726
Davletshin AI et al. [Effect of surfactants on peroxidase activity. I. Effect of anionic surfactants]. 1998 Bioorg. Khim. pmid:9702352
Lea MA and Randolph VM Induction of reporter gene expression by inhibitors of histone deacetylase. 1998 Jul-Aug Anticancer Res. pmid:9703934