butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Endometrial Neoplasms D016889 30 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
HIV Infections D015658 20 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Weight Gain D015430 101 associated lipids
Gastrinoma D015408 1 associated lipids
Dementia, Vascular D015140 7 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Uremia D014511 33 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Thrombosis D013927 49 associated lipids
Thalassemia D013789 8 associated lipids
Starvation D013217 47 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Terova G et al. Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. 2016 PLoS ONE pmid:27471849
Jawed K et al. Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. 2016 PLoS ONE pmid:27466817
Gargari G et al. Consumption of a Bifidobacterium bifidum Strain for 4 Weeks Modulates Dominant Intestinal Bacterial Taxa and Fecal Butyrate in Healthy Adults. 2016 Appl. Environ. Microbiol. pmid:27451450
Teixeira C et al. Effects of variety and steeping conditions on some barley components associated with colonic health. 2016 J. Sci. Food Agric. pmid:27450418
Zhou J et al. Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. 2016 Lipids Health Dis pmid:27449927
Astakhova L et al. Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. 2016 PLoS ONE pmid:27441625
Bai G et al. Dietary Casein and Soy Protein Isolate Modulate the Effects of Raffinose and Fructooligosaccharides on the Composition and Fermentation of Gut Microbiota in Rats. 2016 J. Food Sci. pmid:27434756
Petry FS et al. Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. 2016 Behav. Brain Res. pmid:27025446
Frycz BA et al. Transcript level of AKR1C3 is down-regulated in gastric cancer. 2016 Biochem. Cell Biol. pmid:27019068
Li H et al. Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. 2016 Brain Res. pmid:27017959
Ortega JF et al. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. 2016 Oncotarget pmid:27013579
Sjöblom M et al. Catalytic upgrading of butyric acid towards fine chemicals and biofuels. 2016 FEMS Microbiol. Lett. pmid:26994015
Zhao Z et al. Potential enhancement of direct interspecies electron transfer for syntrophic metabolism of propionate and butyrate with biochar in up-flow anaerobic sludge blanket reactors. 2016 Bioresour. Technol. pmid:26967338
Sun J et al. Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. 2016 Neurosci. Lett. pmid:26957230
Su CL et al. Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. 2016 J Psychiatr Res pmid:26921875
Han A et al. Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. 2016 J. Cell. Physiol. pmid:26661480
Tiwari P et al. Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. 2016 Biochimie pmid:26655363
Valvassori SS et al. Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. 2016 Psychiatry Res pmid:26654753
Mátis G et al. Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. 2016 J Anim Physiol Anim Nutr (Berl) pmid:26614344
Luceri C et al. Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. 2016 Dig Liver Dis pmid:26607831
Kratsman N et al. Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. 2016 Neuropharmacology pmid:26577018
Contreras-Leal E et al. Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines. 2016 Mol. Carcinog. pmid:26331238
Reddy YS et al. Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. 2016 J Oleo Sci pmid:26666272
Kim M et al. Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity. 2016 Bioresour. Technol. pmid:27474955
Xing X et al. Sodium butyrate protects against oxidative stress in HepG2 cells through modulating Nrf2 pathway and mitochondrial function. 2016 J. Physiol. Biochem. pmid:28600747
Huang H et al. Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. 2016 Cell. Mol. Immunol. pmid:25683610
Tian H et al. Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor. 2016 Molecules pmid:27854343
Neis EP et al. Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. 2016 PLoS ONE pmid:27835668
Khairy H et al. The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. 2016 Lett. Appl. Microbiol. pmid:27564089
Kong X et al. Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. 2016 Bioresour. Technol. pmid:26998799
Bencsik R et al. Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. 2016 Stem Cell Res pmid:27591479
Sasajima H et al. Intranasal Administration of Rotenone to Mice Induces Dopaminergic Neurite Degeneration of Dopaminergic Neurons in the Substantia Nigra. 2017 Biol. Pharm. Bull. pmid:28049942
Kurano M et al. Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. 2017 PLoS ONE pmid:28494002
Wang L et al. Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin-angiotensin system. 2017 J. Hypertens. pmid:28509726
Dou X et al. Sodium butyrate improves porcine host defense peptide expression and relieves the inflammatory response upon Toll-like receptor 2 activation and histone deacetylase inhibition in porcine kidney cells. 2017 Oncotarget pmid:28460447
Pant K et al. Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells. 2017 Redox Biol pmid:28288414
Niwińska B et al. Review: Exogenous butyrate: implications for the functional development of ruminal epithelium and calf performance. 2017 Animal pmid:28193308
Jaworska J et al. The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. 2017 J Neuroinflammation pmid:28187734
Pant K et al. Oxidative stress plays a key role in butyrate-mediated autophagy via Akt/mTOR pathway in hepatoma cells. 2017 Chem. Biol. Interact. pmid:28600122
Yang S et al. Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells. 2017 Chem. Res. Toxicol. pmid:28595002
Zapletal O et al. Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models. 2017 Arch. Toxicol. pmid:27830268
Tian L et al. Sodium butyrate improved intestinal immune function associated with NF-κB and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella). 2017 Fish Shellfish Immunol. pmid:28546021
Wu Q et al. Insights from the complete genome sequence of Clostridium tyrobutyricum provide a platform for biotechnological and industrial applications. 2017 J. Ind. Microbiol. Biotechnol. pmid:28536840
Kihara T et al. Bacillus cereus-type polyhydroxyalkanoate biosynthetic gene cluster contains R-specific enoyl-CoA hydratase gene. 2017 Biosci. Biotechnol. Biochem. pmid:28532241
Payandeh S et al. Probiotic supplementation effects on milk fatty acid profile in ewes. 2017 J. Dairy Res. pmid:28524013
Donovan JD et al. In Vitro Digestion and Fermentation of Microencapsulated Tributyrin for the Delivery of Butyrate. 2017 J. Food Sci. pmid:28485486
Huang JC et al. [Protective effect of histone acetylation against cortical injury in neonatal rats]. 2017 Zhongguo Dang Dai Er Ke Za Zhi pmid:28100329
Albuquerque Filho MO et al. Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats. 2017 Neuroscience pmid:28089578
Kataoka N et al. Butyrate production under aerobic growth conditions by engineered Escherichia coli. 2017 J. Biosci. Bioeng. pmid:28089378
Hichino A et al. Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. 2017 J. Biol. Chem. pmid:28057758