butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zhang B et al. | Human papillomavirus type 16 E7 protein increases acetylation of histone H3 in human foreskin keratinocytes. | 2004 | Virology | pmid:15476886 |
Kasumov VT et al. | Spectroscopic and electrochemical characterization of di-tert-butylated sterically hindered Schiff bases and their phenoxyl radicals. | 2004 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:15477142 |
Ichikawa K et al. | Heat shock decreases nuclear transport of 3,5,3'-triiodo-L-thyronine in clone 9 cells. | 1992 | Endocrinology | pmid:1547743 |
Weinberg RS et al. | Butyrate increases the efficiency of translation of gamma-globin mRNA. | 2005 | Blood | pmid:15479724 |
White JB et al. | Characterization of 3',5' cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: absence of functional PDE6. | 2004 | Mol. Vis. | pmid:15480303 |
Liu CA et al. | Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis. | 2004 | Oncogene | pmid:15480428 |
Calabrese V et al. | Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. | 2004 | Arch. Biochem. Biophys. | pmid:15488476 |
Miki K et al. | Butyrate suppresses hypoxia-inducible factor-1 activity in intestinal epithelial cells under hypoxic conditions. | 2004 | Shock | pmid:15489637 |
Sass H and Cypionka H | Isolation of sulfate-reducing bacteria from the terrestrial deep subsurface and description of Desulfovibrio cavernae sp. nov. | 2004 | Syst. Appl. Microbiol. | pmid:15490555 |
Canes D et al. | Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo. | 2005 | Int. J. Cancer | pmid:15499627 |
Hamodeh SA et al. | Mechanism of butyrate-induced hyperpolarization of cultured rat myenteric neurones. | 2004 | Neurogastroenterol. Motil. | pmid:15500516 |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Daniel C et al. | p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15504345 |
Mühl H et al. | The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells. | 2004 | Br. J. Pharmacol. | pmid:15504750 |
Cuff MA and Shirazi-Beechey SP | The importance of butyrate transport to the regulation of gene expression in the colonic epithelium. | 2004 | Biochem. Soc. Trans. | pmid:15506978 |
Kis LL et al. | In vitro EBV-infected subline of KMH2, derived from Hodgkin lymphoma, expresses only EBNA-1, while CD40 ligand and IL-4 induce LMP-1 but not EBNA-2. | 2005 | Int. J. Cancer | pmid:15514968 |
Bandyopadhyay D et al. | Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway. | 2004 | Cancer Res. | pmid:15520174 |
Khan KM and Edwards CA | In vitro fermentation characteristics of a mixture of Raftilose and guar gum by human faecal bacteria. | 2005 | Eur J Nutr | pmid:15526209 |
Guzmán-Aránguez A et al. | Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5. | 2005 | J. Cell. Biochem. | pmid:15526283 |
Arvans DL et al. | Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15528251 |
Ramos MG et al. | Butyrate increases apoptosis induced by different antineoplastic drugs in monocytic leukemia cells. | 2004 | Chemotherapy | pmid:15528887 |
Oh YK et al. | Thermophilic biohydrogen production from glucose with trickling biofilter. | 2004 | Biotechnol. Bioeng. | pmid:15532039 |
Turner JE et al. | Characterization of Arabidopsis fluoroacetate-resistant mutants reveals the principal mechanism of acetate activation for entry into the glyoxylate cycle. | 2005 | J. Biol. Chem. | pmid:15533942 |
Awawdeh MS et al. | Effects of ammonia load on methionine utilization by growing steers. | 2004 | J. Anim. Sci. | pmid:15537774 |
Kristensen NB and Harmon DL | Effect of increasing ruminal butyrate absorption on splanchnic metabolism of volatile fatty acids absorbed from the washed reticulorumen of steers. | 2004 | J. Anim. Sci. | pmid:15537776 |
Soto-Navarro SA et al. | Effect of fiber-based creep feed on intake, digestion, ruminal fermentation, and microbial efficiency in nursing calves. | 2004 | J. Anim. Sci. | pmid:15537777 |
Lardy GP et al. | Effects of increasing level of supplemental barley on forage intake, digestibility, and ruminal fermentation in steers fed medium-quality grass hay. | 2004 | J. Anim. Sci. | pmid:15537788 |
Gaudier E et al. | Butyrate regulation of glycosylation-related gene expression: evidence for galectin-1 upregulation in human intestinal epithelial goblet cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15541394 |
Sena-Esteves M et al. | Optimized large-scale production of high titer lentivirus vector pseudotypes. | 2004 | J. Virol. Methods | pmid:15542136 |
Manzanilla EG et al. | Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs. | 2004 | J. Anim. Sci. | pmid:15542467 |
Miller SJ | Cellular and physiological effects of short-chain fatty acids. | 2004 | Mini Rev Med Chem | pmid:15544545 |
Marteau P et al. | Cellular and physiological effects of probiotics and prebiotics. | 2004 | Mini Rev Med Chem | pmid:15544550 |
DeFrain JM et al. | Feeding glycerol to transition dairy cows: effects on blood metabolites and lactation performance. | 2004 | J. Dairy Sci. | pmid:15545383 |
Kanso S and Patel BK | Phenylobacterium lituiforme sp. nov., a moderately thermophilic bacterium from a subsurface aquifer, and emended description of the genus Phenylobacterium. | 2004 | Int. J. Syst. Evol. Microbiol. | pmid:15545448 |
Nabandith V et al. | Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. | Asian Pac. J. Cancer Prev. | pmid:15546251 | |
Klehr D et al. | Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate. | 1992 | Biochemistry | pmid:1554707 |
Louis M et al. | The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative stress. | 2004 | Int. J. Oncol. | pmid:15547708 |
Lewis LR and Levine AE | Sodium butyrate alters the response of a human colon carcinoma cell line to transforming growth factor-beta 1. | 1992 | Cancer Lett. | pmid:1555205 |
Fagan P et al. | Determination of mono- and di-acylglycerols in milk lipids. | 2004 | J Chromatogr A | pmid:15553151 |
Li X et al. | Butyrate reduces liver metastasis of rat colon carcinoma cells in vivo and resistance to oxidative stress in vitro. | 2004 | Clin. Exp. Metastasis | pmid:15554389 |
Bennegadi-Laurent N et al. | Nutritional and sanitary statuses alter postweaning development of caecal microbial activity in the rabbit. | 2004 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:15556384 |
Sakai M et al. | Studies on the conditions required for structural and functional maturation of rabies virus glycoprotein (G) in G cDNA-transfected cells. | 2004 | Microbiol. Immunol. | pmid:15557743 |
De Vriese C et al. | Ghrelin is produced by the human erythroleukemic HEL cell line and involved in an autocrine pathway leading to cell proliferation. | 2005 | Endocrinology | pmid:15564328 |
Tatara M et al. | High-rate thermophilic methane fermentation on short-chain fatty acids in a down-flow anaerobic packed-bed reactor. | 2005 | Bioprocess Biosyst Eng | pmid:15565281 |
Huang YQ et al. | Effects of cell cycle on telomerase activity and on hepatitis B virus replication in HepG2 2.2.15 cells. | 2004 | HBPD INT | pmid:15567742 |
Kato K et al. | Randomized placebo-controlled trial assessing the effect of bifidobacteria-fermented milk on active ulcerative colitis. | 2004 | Aliment. Pharmacol. Ther. | pmid:15569116 |
Zheng XJ and Yu HQ | Inhibitory effects of butyrate on biological hydrogen production with mixed anaerobic cultures. | 2005 | J. Environ. Manage. | pmid:15572082 |
Daniels T et al. | Effects of valproic acid on cardiac metabolism. | 2004 | Can. J. Physiol. Pharmacol. | pmid:15573154 |
Dhillon VS et al. | CpG methylation of the FHIT, FANCF, cyclin-D2, BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian origin. | 2004 | Mol. Cancer | pmid:15574200 |
Ebert PS et al. | Evidence for multiple sites of regulation of heme synthesis in murine erythroleukemia cells. | 1979 | J. Natl. Cancer Inst. | pmid:155751 |
Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
Decroos K et al. | Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions. | 2005 | Arch. Microbiol. | pmid:15578160 |
Zhang Y and Hamburger AW | Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling. | 2005 | Br. J. Cancer | pmid:15583694 |
Vlaeminck B et al. | Rumen odd and branched chain fatty acids in relation to in vitro rumen volatile fatty acid productions and dietary characteristics of incubated substrates. | 2004 | J Anim Physiol Anim Nutr (Berl) | pmid:15584949 |
Roivainen A et al. | Biodistribution and blood metabolism of 1-11C-methyl-4-piperidinyl n-butyrate in humans: an imaging agent for in vivo assessment of butyrylcholinesterase activity with PET. | 2004 | J. Nucl. Med. | pmid:15585478 |
Wakabayashi K et al. | Gene expression associated with the decrease in malignant phenotype of human liver cancer cells following stimulation with a histone deacetylase inhibitor. | 2005 | Int. J. Oncol. | pmid:15586245 |
Karasawa Y and Okisaka S | Inhibition of histone deacetylation by butyrate induces morphological changes in Y79 retinoblastoma cells. | 2004 Nov-Dec | Jpn. J. Ophthalmol. | pmid:15592778 |
Zduńczyk Z et al. | Performance and caecal adaptation of turkeys to diets without or with antibiotic and with different levels of mannan-oligosaccharide. | 2004 | Arch Anim Nutr | pmid:15595620 |
Juśkiewicz J and Zduńczyk Z | Effects of cellulose, carboxymethylcellulose and inulin fed to rats as single supplements or in combinations on their caecal parameters. | 2004 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:15596397 |
Ravizza R et al. | Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin. | 2004 | BMC Cancer | pmid:15601469 |
Zhao Y et al. | Histone acetylation regulates both transcription initiation and elongation of hsp22 gene in Drosophila. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15607742 |
Cho Y et al. | An inverse relationship between ceramide synthesis and clinical severity in patients with psoriasis. | 2004 | J. Korean Med. Sci. | pmid:15608398 |
Bian F et al. | Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. | 2005 | J. Biol. Chem. | pmid:15611129 |
Nafday SM et al. | Short-chain fatty acids induce colonic mucosal injury in rats with various postnatal ages. | 2005 | Pediatr. Res. | pmid:15611351 |
Fu H et al. | Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2. | 2004 | Chin J Dig Dis | pmid:15612246 |
Morioka K et al. | Erythroid differentiation and poly(ADP-ribose) synthesis in Friend leukemia cells. | 1979 | Gan | pmid:156137 |
Kim JD and Kang KH | Isolation of Lactobacillus sakei strain KJ-2008 and its removal of characteristic malodorous gases under anaerobic culture conditions. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15618611 |
Wang P et al. | [Sodium butyrate induces rat hepatic oval cells differentiating into mature hepatocytes in vitro]. | 2004 | Zhonghua Gan Zang Bing Za Zhi | pmid:15619336 |
Lee JY et al. | Thiobutacin, a novel antifungal and antioomycete antibiotic from Lechevalieria aerocolonigenes. | 2004 | J. Nat. Prod. | pmid:15620255 |
Rahmani M et al. | Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change. | 2005 | Mol. Pharmacol. | pmid:15625278 |
Hirshfield S et al. | Crystal methamphetamine use predicts incident STD infection among men who have sex with men recruited online: a nested case-control study. | 2004 | J. Med. Internet Res. | pmid:15631965 |
Shivshankar P and Devi SC | Screening of stimulatory effects of dietary risk factors on mouse intestinal cell kinetics. | 2005 | World J. Gastroenterol. | pmid:15633224 |
Bordin M et al. | Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. | 2004 | Mol. Cancer Res. | pmid:15634758 |
Machavaram KK et al. | Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats. | 2004 | Pharmazie | pmid:15638086 |
Jagielski AK et al. | The role of intracellular cAMP in renal gluconeogenesis in view of differential action of various cAMP analogues. | 2005 | Arch. Biochem. Biophys. | pmid:15639228 |
Monneret C | Histone deacetylase inhibitors. | 2005 | Eur J Med Chem | pmid:15642405 |
Sezik E et al. | Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay-directed fractionation techniques. | 2005 | Life Sci. | pmid:15642593 |
Hristov AN et al. | Effect of carbohydrate source on ammonia utilization in lactating dairy cows. | 2005 | J. Anim. Sci. | pmid:15644514 |
Kuroda J et al. | Promotion of cell differentiation, and suppression of cell growth and cyclooxygenase-2 expression by differentiation-inducing agents in human oral squamous carcinoma SCC25 cells. | 2005 | Int. J. Oncol. | pmid:15645120 |
Looby E et al. | Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner. | 2005 | Int. J. Cancer | pmid:15645414 |
Hiesberger T et al. | Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis. | 2005 | J. Biol. Chem. | pmid:15647252 |
Turecková J et al. | Sodium butyrate-mediated differentiation of colorectal cancer cells: regulation of PKCbetaII by PI 3-kinase. | 2005 | Int. J. Mol. Med. | pmid:15647851 |
Hossain Z et al. | Effect of polyunsaturated fatty acid-enriched phosphatidylcholine and phosphatidylserine on butyrate-induced growth inhibition, differentiation and apoptosis in Caco-2 cells. | 2006 Mar-Apr | Cell Biochem. Funct. | pmid:15648055 |
Zlotnik Y et al. | Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay. | 2005 | Br. J. Cancer | pmid:15655545 |
Hanafusa T et al. | Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation. | 2005 | BMC Cancer | pmid:15661074 |
Aulenta F et al. | Assessment of natural or enhanced in situ bioremediation at a chlorinated solvent-contaminated aquifer in Italy: a microcosm study. | 2005 | Environ Int | pmid:15661281 |
Rozental R et al. | Sodium butyrate induces apoptosis in MSN neuroblastoma cells in a calcium independent pathway. | 2004 | Neurochem. Res. | pmid:15662847 |
Küçük A et al. | Investigation of the pharmacokinetics and determination of tramadol in rabbit plasma by a high-performance liquid chromatography-diode array detector method using liquid-liquid extraction. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15664351 |
Ganapathy V et al. | Biological functions of SLC5A8, a candidate tumour suppressor. | 2005 | Biochem. Soc. Trans. | pmid:15667316 |
Mustafa T et al. | Expression of the epidermal growth factor seven-transmembrane member CD97 correlates with grading and staging in human oral squamous cell carcinomas. | 2005 | Cancer Epidemiol. Biomarkers Prev. | pmid:15668483 |
Vidyasagar S et al. | Role of short-chain fatty acids in colonic HCO(3) secretion. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15677553 |
Peng H et al. | Label-free electrochemical DNA sensor based on functionalised conducting copolymer. | 2005 | Biosens Bioelectron | pmid:15681199 |
Roediger WE | Oxidative and synthetic functions of n-Butyrate in colonocytes. | 1992 | Dis. Colon Rectum | pmid:1568404 |
Ramsay RG et al. | Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS. | 2005 | DNA Cell Biol. | pmid:15684716 |
Hague A et al. | Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis. | 2005 | Br. J. Cancer | pmid:15685228 |
Alkharfy KM et al. | Liquid chromatographic assay of abouthiouzine in plasma and its application to pharmacokinetic studies. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15686983 |
Lykke-Andersen J and Wagner E | Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. | 2005 | Genes Dev. | pmid:15687258 |
Joseph J et al. | Role of p53 status in chemosensitivity determination of cancer cells against histone deacetylase inhibitor sodium butyrate. | 2005 | Int. J. Cancer | pmid:15688418 |
Hadjiagapiou C et al. | Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate transporter 1 promoter. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15691871 |
Collins JF et al. | c-myc antisense oligonucleotides inhibit the colony-forming capacity of Colo 320 colonic carcinoma cells. | 1992 | J. Clin. Invest. | pmid:1569190 |