butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hutt-Taylor SR et al. | Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60. | 1988 | Blood | pmid:2446679 |
Germain L et al. | Promotion of growth and differentiation of rat ductular oval cells in primary culture. | 1988 | Cancer Res. | pmid:2446746 |
Bahn RS et al. | n-Butyrate increases c-erb A oncogene expression in human colon fibroblasts. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2447891 |
Tamura RN and Cox GS | Effect of pyrimidine deoxynucleosides and sodium butyrate on expression of the glycoprotein hormone alpha-subunit and placental alkaline phosphatase in HeLa cells. | 1988 | Biochim. Biophys. Acta | pmid:2449248 |
Halgunset J et al. | Butyrate effects on growth, morphology, and fibronectin production in PC-3 prostatic carcinoma cells. | 1988 | Prostate | pmid:2450342 |
Ladoux A et al. | An increase in intracellular pH is a general response of promonocytic cells to differentiating agents. | 1988 | FEBS Lett. | pmid:2455658 |
Kassis S et al. | Modulation of the beta-adrenergic receptor-coupled adenylate cyclase by chemical inducers of differentiation: effects on beta receptors and the inhibitory regulatory protein Gi. | 1988 | J. Recept. Res. | pmid:2455808 |
Germain L et al. | Biliary epithelial and hepatocytic cell lineage relationships in embryonic rat liver as determined by the differential expression of cytokeratins, alpha-fetoprotein, albumin, and cell surface-exposed components. | 1988 | Cancer Res. | pmid:2457432 |
Sorimachi K et al. | Requirement of serum pretreatment for induction of alkaline phosphatase activity with prednisolone, butyrate, dibutyryl cyclic adenosine monophosphate and NaCl in human liver cells continuously cultured in serum-free medium. | 1988 | Cell Struct. Funct. | pmid:2836073 |
Lee KL et al. | The effects of sodium butyrate on the retinoic acid-induced changes in 1,25-dihydroxyvitamin D3 receptors in tumorigenic and nontumorigenic bone derived cell lines. | 1988 | Endocrinology | pmid:2836162 |
Gross JL et al. | Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate. | 1988 | Cancer Res. | pmid:3121170 |
Perrine SP et al. | Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2460870 |
Herlyn M et al. | Regulatory factors that determine growth and phenotype of normal human melanocytes. | 1988 | Exp. Cell Res. | pmid:2461309 |
Toscani A et al. | Molecular analysis of sodium butyrate-induced growth arrest. | 1988 | Oncogene Res. | pmid:3144695 |
Nishiya I et al. | Relationship between changes of the steroid receptor and synchronization in human endometrial adenocarcinoma cells in vitro. | 1988 | Cytometry | pmid:3208623 |
Yusta B et al. | Mechanism of L-triiodothyronine (T3) uptake by glial C6 cells: regulation by butyrate. | 1988 | Mol. Cell. Endocrinol. | pmid:3208994 |
Ortiz-Caro J et al. | Proliferation and differentiation are not directly related to H1(0) accumulation in cultured glial cells. | 1988 | Brain Res. | pmid:3219583 |
Takenaga K et al. | Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells. | 1988 | Mol. Cell. Biol. | pmid:3221870 |
Maddox AM and Haddox MK | Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells. | 1988 | Exp. Cell Biol. | pmid:2903078 |
Hellweg R et al. | Nerve growth factor synthesis in cultured rat iris: modulation by endogenous transmitter substances. | 1988 | Exp. Cell Res. | pmid:2844567 |
Laeng H et al. | Participation of mitochondrial proliferation in morphological differentiation of murine mastocytoma cells. | 1988 | Exp. Cell Res. | pmid:2844569 |
Ryan MP and Higgins PJ | Cytoarchitecture of Kirsten sarcoma virus-transformed rat kidney fibroblasts: butyrate-induced reorganization within the actin microfilament network. | 1988 | J. Cell. Physiol. | pmid:2844835 |
Kaneko Y et al. | Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2843181 |
Sutherland GR et al. | A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures. | 1988 | Cytogenet. Cell Genet. | pmid:2843323 |
Powers AC et al. | Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone. | 1988 | Diabetes | pmid:2843409 |
Suzuki J et al. | Photochemical mutagen formation from aerobically treated night-soil effluent and the contributive substances. | 1988 | Environ. Pollut. | pmid:15092599 |
Staecker JL and Pitot HC | The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. | 1988 | Arch. Biochem. Biophys. | pmid:2895606 |
Chan WC et al. | Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents. | 1988 | Blood | pmid:2961380 |
Effects of short-chain fatty acids on a human colon carcinoma cell line. | 1988 | Nutr. Rev. | pmid:3340339 | |
Hallows KR et al. | Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells. | 1988 | Radiat. Res. | pmid:3340722 |
Berry RD and Paraskeva C | Expression of carcinoembryonic antigen by adenoma and carcinoma derived epithelial cell lines: possible marker of tumour progression and modulation of expression by sodium butyrate. | 1988 | Carcinogenesis | pmid:3345582 |
Annunziato AT et al. | Treatment with sodium butyrate inhibits the complete condensation of interphase chromatin. | 1988 | Chromosoma | pmid:3349872 |
Leith JT | Effects of sodium butyrate and 3-aminobenzamide on survival of Chinese hamster HA-1 cells after X irradiation. | 1988 | Radiat. Res. | pmid:3353504 |
Reynier MO et al. | Influence of lipid-rich diets on intestinal cholesterol uptake. | 1988 | Ann. Nutr. Metab. | pmid:3355108 |
Zhang DE and Nelson DA | Histone acetylation in chicken erythrocytes. Rates of deacetylation in immature and mature red blood cells. | 1988 | Biochem. J. | pmid:3355515 |
Lacroix J et al. | In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. | 1988 Jul-Aug | Anticancer Res. | pmid:3052247 |
Tocco DJ et al. | Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906591 |
Tocco DJ et al. | The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906592 |
Zielke HR et al. | Synthesis of glutamate and glutamine in dibutyryl cyclic AMP-treated astrocytes. | 1989 | Neurosci. Lett. | pmid:2563906 |
Thakur MK and Prasad S | Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate. | 1989 | Mutat. Res. | pmid:2927415 |
Montiel F et al. | Presence of insulin receptors in cultured glial C6 cells. Regulation by butyrate. | 1989 | Biochem. J. | pmid:2930502 |
Darzynkiewicz Z and Carter SP | Thermal stability of nucleosomes studied in situ by flow cytometry: effect of ionic strength and n-butyrate. | 1989 | Exp. Cell Res. | pmid:2464501 |
Kwong L and Weeks G | Studies on the accumulation of the differentiation-inducing factor (DIF) in high-cell-density monolayers of Dictyostelium discoideum. | 1989 | Dev. Biol. | pmid:2466719 |
Mavilio F et al. | Alteration of growth and differentiation factors response by Kirsten and Harvey sarcoma viruses in the IL-3-dependent murine hematopoietic cell line 32D C13(G). | 1989 | Oncogene | pmid:2468124 |
Denburg JA et al. | Factors influencing basophilic differentiation of HL-60 cells. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2468609 |
Katoh K and Yajima T | Effects of butyric acid and analogues on amylase release from pancreatic segments of sheep and goats. | 1989 | Pflugers Arch. | pmid:2470024 |
Schmidt R et al. | Sodium butyrate selectively antagonizes the inhibitory effect of retinoids on cornified envelope formation in cultured human keratinocytes. | 1989 | J. Cell. Physiol. | pmid:2473084 |
Vaziri ND et al. | Effect of experimental azotemia on intestinal transport of butyric acid. | 1989 | Proc. Soc. Exp. Biol. Med. | pmid:2915995 |
Perrine SP et al. | Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia. | 1989 | Blood | pmid:2473801 |
Higgins PJ and Ryan MP | Biochemical localization of the transformation-sensitive 52 kDa (p52) protein to the substratum contact regions of cultured rat fibroblasts. Butyrate induction, characterization, and quantification of p52 in v-ras transformed cells. | 1989 | Biochem. J. | pmid:2920008 |
Pramanik SK and Bag J | Expression of muscle-specific proteins is necessary to regulate translation of the mRNA for a 40-kDa housekeeping polypeptide in rat L6 cells. | 1989 | Eur. J. Biochem. | pmid:2473901 |
Myers DE et al. | The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins. | 1989 | J. Immunol. Methods | pmid:2474026 |
Arock M et al. | Histamine-releasing activity of endogenous peptides on mast cells derived from different sites and species. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2474510 |
Weaver GA et al. | Constancy of glucose and starch fermentations by two different human faecal microbial communities. | 1989 | Gut | pmid:2920921 |
Chen HM and Lifschitz CH | Preparation of fecal samples for assay of volatile fatty acids by gas-liquid chromatography and high-performance liquid chromatography. | 1989 | Clin. Chem. | pmid:2910583 |
Malik Z et al. | Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins. | 1989 | J. Photochem. Photobiol. B, Biol. | pmid:2512381 |
Lehman TA et al. | Metabolism of and DNA adduct formation by benzo[alpha]pyrene in human skin epithelial cells in vitro pretreated with cytochrome P450 modulators. | 1989 | Cancer Biochem. Biophys. | pmid:2515917 |
Knight SC et al. | Lithium and hydrocortisone interactions on cell growth and gene expression in human promyelocytic leukemia (HL60). | 1989 | Leuk. Res. | pmid:2523989 |
Suen CS and Wilk S | Sodium butyrate induces pyroglutamyl peptidase I and decreases thyrotropin-releasing hormone receptors in GH3 cells. | 1989 | Endocrinology | pmid:2564336 |
Constantoulakis P et al. | On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC. | 1989 | Blood | pmid:2478217 |
Ramsdell JS and Tashjian AH | GH4 pituitary cell variants selected as nonresponsive to thyrotropin-releasing hormone-enhanced substratum adhesion are nonresponsive to epidermal growth factor: evidence for a common signaling defect. | 1989 | J. Cell. Physiol. | pmid:2480354 |
Alberts P | Effects of N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate, adenosine, and of oxotremorine and 3-isobutyl-1-methylxanthine on the electrically evoked [3H]acetylcholine secretion in the guinea-pig ileum myenteric plexus. | 1989 | Acta Physiol. Scand. | pmid:2481381 |
Kubin T et al. | Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate. | 1989 | Cell Biol. Int. Rep. | pmid:2481569 |
Clarke J et al. | A comparison of the effects of various stimulatory agents on t-PA secretion by normal and malignant cell lines. | 1989 | Cell Biochem. Funct. | pmid:2481573 |
Nackerdien Z et al. | Chromatin decondensed by acetylation shows an elevated radiation response. | 1989 | Radiat. Res. | pmid:2922469 |
Binder HJ and Mehta P | Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon. | 1989 | Gastroenterology | pmid:2925072 |
Del Terzo S et al. | Iontophoretic transport of a homologous series of ionized and nonionized model compounds: influence of hydrophobicity and mechanistic interpretation. | 1989 | Pharm. Res. | pmid:2717524 |
Bloom EJ et al. | Effect of sodium butyrate, a differentiating agent, on cell surface glycoconjugates of a human pancreatic cell line. | 1989 | Pancreas | pmid:2717602 |
Aller P et al. | Modification of cell growth-dependent gene transcript levels by sodium butyrate in serum stimulated fibroblasts. | 1989 | Biochem. Int. | pmid:2719709 |
Yu BS et al. | Dynamic properties of interaction between nucleic acid bases and models of amino acids. | 1989 | Biochem. Int. | pmid:2719711 |
Watanabe S et al. | Expression of the germ cell alkaline phosphatase gene in human choriocarcinoma cells. | 1989 | J. Biol. Chem. | pmid:2745460 |
Vijayaraghavan S et al. | Calcium uptake by bovine epididymal spermatozoa is regulated by the redox state of the mitochondrial pyridine nucleotides. | 1989 | Biol. Reprod. | pmid:2752074 |
Hock RA et al. | Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines. | 1989 | Blood | pmid:2752148 |
Champelovier P et al. | Establishment and characterization of a granulocytic subclone (UM 384) from the monoblastic cell line U 937. | 1989 | Exp. Hematol. | pmid:2753087 |
Ortiz-Caro J et al. | Organization of the thyroid hormone receptor in the chromatin of C6 glial cells: evidence that changes in receptor levels are not associated with changes in receptor distribution. | 1989 | FEBS Lett. | pmid:2753141 |
Firmansyah A et al. | Isolated colonocyte metabolism of glucose, glutamine, n-butyrate, and beta-hydroxybutyrate in malnutrition. | 1989 | Gastroenterology | pmid:2753323 |
Favinger J et al. | Rhodospirillum centenum, sp. nov., a thermotolerant cyst-forming anoxygenic photosynthetic bacterium. | 1989 | Antonie Van Leeuwenhoek | pmid:2757370 |
Marchant P et al. | A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation. | 1989 | Arch. Biochem. Biophys. | pmid:2757387 |
Herz F | Effect of human serum on alkaline phosphatase induction in cultured human tumor cells. | 1989 | Experientia | pmid:2759209 |
Furukawa M et al. | [Suppressive effect of CDDP on induction of the Epstein-Barr virus antigen synthesis by n-butyrate]. | 1989 | Nippon Jibiinkoka Gakkai Kaiho | pmid:2545850 |
Iavarone A et al. | 3-D changes in neuroblastoma x glioma hybrid (NG 108-15) cell differentiation as studied by SEM and TEM. | 1989 | Prog. Clin. Biol. Res. | pmid:2546164 |
Sussman NL et al. | Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. | 1989 | Am. J. Physiol. | pmid:2546440 |
Ryan MP and Higgins PJ | Sodium-n-butyrate induces secretion and substrate accumulation of p52 in Kirsten sarcoma virus-transformed rat kidney fibroblasts. | 1989 | Int. J. Biochem. | pmid:2546834 |
Yanase S and Sugawara K | Inhibition of chemical Epstein-Barr virus induction by dimethyl sulfoxide and related polar compounds. | 1989 | Intervirology | pmid:2546900 |
Poduslo SE | Induction of ketone body enzymes in glial cells. | 1989 | Arch. Biochem. Biophys. | pmid:2568818 |
Zielke HR et al. | Effect of nerve growth factor on the synthesis of amino acids in PC12 cells. | 1989 | J. Neurosci. Res. | pmid:2569539 |
Yang ZW et al. | Expression of (+)-3-PPP binding sites in the PC12 pheochromocytoma cell line. | 1989 | Eur. J. Pharmacol. | pmid:2569979 |
Shirasuna K et al. | Different contents of glycosaminoglycans in a human neoplastic salivary duct cell line and its subclone with a myoepithelial phenotype. | 1989 | Virchows Arch., B, Cell Pathol. | pmid:2570484 |
Mickley LA et al. | Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents. | 1989 | J. Biol. Chem. | pmid:2572588 |
Bates SE et al. | Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation. | 1989 | Mol. Cell. Biol. | pmid:2573830 |
Wasserman L et al. | Sodium butyrate enhances the activities of membranal enzymes and increases drug sensitivity in a cell line from ascitic fluid of an ovarian carcinoma patient. | 1989 | Eur J Cancer Clin Oncol | pmid:2576649 |
Sorimachi K et al. | Inhibitory effect of dibutyryl cyclic adenosine monophosphate on the induction of alkaline phosphatase in human fetal liver cell line. | 1989 | Biochim. Biophys. Acta | pmid:2535785 |
Benjamin LA et al. | Alterations in plasminogen activator and inhibitor activity during the differentiation of a human neuroblastoma cell line, SMS-KAN. | 1989 | Cancer Lett. | pmid:2537681 |
Perrine SP et al. | Butyrate analogues modulate globin gene expression in human and ovine erythroid cells. | 1989 | Prog. Clin. Biol. Res. | pmid:2616579 |
Okabayashi K et al. | Effect of butyrate on the expression of the human preprourokinase gene introduced into Chinese hamster ovary cells. | 1989 | Cell Struct. Funct. | pmid:2620348 |
Kumagai S et al. | [Assessment of occupational exposures to industrial hazardous substances. III. On the frequency distribution of daily exposure averages (8-h TWA)]. | 1989 | Sangyo Igaku | pmid:2585804 |
Nakamaki T et al. | UV-induced DNA repair in leukemic cell differentiation. | 1989 | Nippon Ketsueki Gakkai Zasshi | pmid:2588962 |
Yano S and Tierney DF | Butyrate increases catalase activity and protects rat pulmonary artery smooth muscle cells against hyperoxia. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2590195 |
Fitz JG et al. | Effect of pH on membrane potential and K+ conductance in cultured rat hepatocytes. | 1989 | Am. J. Physiol. | pmid:2558580 |
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