butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Machiels K et al. | A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. | 2014 | Gut | pmid:24021287 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Katzenmaier EM et al. | Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro. | 2014 | Anticancer Res. | pmid:25275038 |
Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |
Valvassori SS et al. | Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress. | 2014 | Curr Neurovasc Res | pmid:25233278 |
Nankova BB et al. | Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders. | 2014 | PLoS ONE | pmid:25170769 |
Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
Chou AH et al. | Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. | 2014 | Brain Res. | pmid:25139423 |
Reindl A et al. | Enumeration of clostridia in goat milk using an optimized membrane filtration technique. | 2014 | J. Dairy Sci. | pmid:25129496 |
Grandner MA et al. | Sleep symptoms associated with intake of specific dietary nutrients. | 2014 | J Sleep Res | pmid:23992533 |
Peterson EC and Daugulis AJ | Demonstration of in situ product recovery of butyric acid via CO2 -facilitated pH swings and medium development in two-phase partitioning bioreactors. | 2014 | Biotechnol. Bioeng. | pmid:23996152 |
Milbradt EL et al. | Control of Salmonella Enteritidis in turkeys using organic acids and competitive exclusion product. | 2014 | J. Appl. Microbiol. | pmid:24797347 |
Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
Saini M et al. | Metabolic engineering of Escherichia coli for production of butyric acid. | 2014 | J. Agric. Food Chem. | pmid:24773075 |
Dareioti MA et al. | Effect of pH on the anaerobic acidogenesis of agroindustrial wastewaters for maximization of bio-hydrogen production: a lab-scale evaluation using batch tests. | 2014 | Bioresour. Technol. | pmid:24759638 |
Castellano JF et al. | Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging. | 2014 | Hippocampus | pmid:24753063 |
Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Han A et al. | Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. | 2014 | Neuropharmacology | pmid:24607816 |
Park HG et al. | Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24606669 |
Kato R et al. | The synergistic effect of 1'-acetoxychavicol acetate and sodium butyrate on the death of human hepatocellular carcinoma cells. | 2014 | Chem. Biol. Interact. | pmid:24480522 |
Saldanha SN et al. | Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. | 2014 | Exp. Cell Res. | pmid:24518414 |
Cerisuelo A et al. | The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. | 2014 | Poult. Sci. | pmid:24604853 |
Ronzoni L et al. | Modulation of gamma globin genes expression by histone deacetylase inhibitors: an in vitro study. | 2014 | Br. J. Haematol. | pmid:24606390 |
Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
Tailor D et al. | Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. | 2014 | Mitochondrion | pmid:24177748 |
Peterson AB et al. | Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. | 2014 | Psychopharmacology (Berl.) | pmid:24173624 |
Fang CL et al. | Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets. | 2014 | J Anim Physiol Anim Nutr (Berl) | pmid:24024579 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
Yan SF et al. | HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia. | 2014 | Curr. Pharm. Des. | pmid:23888946 |
Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |
Stertz L et al. | Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. | 2014 Jan-Mar | Rev Bras Psiquiatr | pmid:24346357 |
Turon V et al. | Growth of Chlorella sorokiniana on a mixture of volatile fatty acids: The effects of light and temperature. | 2015 | Bioresour. Technol. | pmid:26461792 |
Zhong Y et al. | Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. | 2015 | Food Funct | pmid:26227569 |
Shimoyama T et al. | Study of the mechanisms of a Japanese traditional fermented medicine in the improvement of constipation. | 2015 | J. Gastroenterol. Hepatol. | pmid:25827805 |