butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Conway RM et al. | Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line. | 1995 | Oncol. Res. | pmid:8527863 |
Sasaki Y et al. | Effects of glucose and butyrate on insulin release from perifused fragments of sheep pancreas. | 1977 | J. Endocrinol. | pmid:853270 |
Cremer JE et al. | Rapid blood-brain transport and metabolism of butyrate and pyruvate in the rat after portocaval anastomosis [proceedings]. | 1977 | J. Physiol. (Lond.) | pmid:853427 |
Newmark HL and Young CW | Butyrate and phenylacetate as differentiating agents: practical problems and opportunities. | 1995 | J. Cell. Biochem. Suppl. | pmid:8538206 |
Nuydens R et al. | Sodium butyrate induces aberrant tau phosphorylation and programmed cell death in human neuroblastoma cells. | 1995 | Brain Res. | pmid:8542327 |
Zhai Y et al. | Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. | 1996 | J. Immunol. | pmid:8543823 |
Nagasawa T et al. | Differences in cellular transport of tri-iodothyronine and thyroxine: cell cycle-dependent alteration of tri-iodothyronine uptake. | 1995 | J. Endocrinol. | pmid:8543918 |
Bhatia U et al. | Induction of cell differentiation potentiates apoptosis triggered by prior exposure to DNA-damaging drugs. | 1995 | Cell Growth Differ. | pmid:8547222 |
Calsamiglia S et al. | Effects of ruminal versus duodenal dosing of fish meal on ruminal fermentation and milk composition. | 1995 | J. Dairy Sci. | pmid:8550909 |
Bartram HP et al. | Effects of deoxycholic acid and butyrate on mucosal prostaglandin E2 release and cell proliferation in the human sigmoid colon. | 1995 May-Jun | JPEN J Parenter Enteral Nutr | pmid:8551644 |
Stringer RE et al. | Sodium butyrate delays neutrophil apoptosis: role of protein biosynthesis in neutrophil survival. | 1996 | Br. J. Haematol. | pmid:8562392 |
Laubach VE et al. | High-level expression of human inducible nitric oxide synthase in Chinese hamster ovary cells and characterization of the purified enzyme. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8579595 |
Yu X et al. | Kinetic analysis of dynamic 13C NMR spectra: metabolic flux, regulation, and compartmentation in hearts. | 1995 | Biophys. J. | pmid:8580353 |
Clausen MR | Butyrate and colorectal cancer in animals and in humans (mini-symposium: butyrate and colorectal cancer). | 1995 | Eur. J. Cancer Prev. | pmid:8580784 |
Pallauf J et al. | Influence of cAMP-effector-agonists on the synthesis of metallothionein in rat primary hepatocytes. | 1995 | Z Ernahrungswiss | pmid:8585245 |
Justus AC et al. | Heparan-dependent endothelial antithrombin binding is increased by butyrate. | 1995 | Thromb. Res. | pmid:8588189 |
Iwai SA et al. | The kinetics of induction of Hox1.6 and C-jun mRNA during three different ways of inducing differentiation in teratocarcinoma F9 cells. | 1995 | In Vitro Cell. Dev. Biol. Anim. | pmid:8589890 |
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Pagés JC et al. | Activation of Moloney murine leukemia virus LTR enhances the titer of recombinant retrovirus in psi CRIP packaging cells. | 1995 | Gene Ther. | pmid:8593605 |
Krupitza G et al. | Genes related to growth and invasiveness are repressed by sodium butyrate in ovarian carcinoma cells. | 1996 | Br. J. Cancer | pmid:8595156 |
Bridges EG et al. | 3'-Azido-3'-deoxythymidine inhibits erythroid-specific transcription factors in human erythroid K562 leukemia cells. | 1996 Jan-Feb | Eur. J. Haematol. | pmid:8599995 |
Buquet-Fagot C et al. | Sodium butyrate inhibits the phosphorylation of the retinoblastoma gene product in mouse fibroblasts by a transcription-dependent mechanism. | 1996 | J. Cell. Physiol. | pmid:8600167 |
Le Roux F et al. | Epstein-Barr virus (EBV) EB1/Zta protein provided in trans and competent for the activation of productive cycle genes does not activate the BZLF1 gene in the EBV genome. | 1996 | J. Gen. Virol. | pmid:8601788 |
Miller G et al. | Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. | 1996 | N. Engl. J. Med. | pmid:8609946 |
Musk SR et al. | Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. | 1995 | Nutr Cancer | pmid:8610048 |
Sharma HW et al. | Differentiation of immortal cells inhibits telomerase activity. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8618897 |
Jaskiewicz J et al. | Catabolism of isobutyrate by colonocytes. | 1996 | Arch. Biochem. Biophys. | pmid:8619613 |
Keusch GT et al. | Comparison of the effects of Shiga-like toxin 1 on cytokine- and butyrate-treated human umbilical and saphenous vein endothelial cells. | 1996 | J. Infect. Dis. | pmid:8627068 |
Turin F et al. | n-Butyrate, a cell cycle blocker, inhibits early amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of duck hepatocytes. | 1996 | J. Virol. | pmid:8627742 |
Chang ST and Yung BY | Potentiation of sodium butyrate-induced apoptosis by vanadate in human promyelocytic leukemia cell line HL-60. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8630006 |
Tilbrook PA et al. | Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin. | 1996 | J. Biol. Chem. | pmid:8631947 |
Kawasaki N et al. | Control of hemoglobin synthesis in erythroid differentiating K562 cells. I. Role of iron in erythroid cell heme synthesis. | 1996 | Arch. Biochem. Biophys. | pmid:8645006 |
Jaster R et al. | Inhibition of proliferation but not erythroid differentiation of J2E cells by rapamycin. | 1996 | Biochem. Pharmacol. | pmid:8645341 |
Lin MC et al. | Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor. | 1979 | J. Biol. Chem. | pmid:86543 |
Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
Vettese-Dadey M et al. | Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. | 1996 | EMBO J. | pmid:8665858 |
Smith TJ et al. | n-Butyrate induces plasminogen activator inhibitor type 1 messenger RNA in cultured Hep G2 cells. | 1996 | Hepatology | pmid:8666343 |
Wiechmann AF | Recoverin in cultured human retinoblastoma cells: enhanced expression during morphological differentiation. | 1996 | J. Neurochem. | pmid:8666979 |
McIntosh GH et al. | A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats. | 1996 | J. Gastroenterol. Hepatol. | pmid:8672754 |
Velázquez OC et al. | Butyrate and the colonocyte. Implications for neoplasia. | 1996 | Dig. Dis. Sci. | pmid:8674394 |
Stein J et al. | Induction of glutathione-S-transferase-pi by short-chain fatty acids in the intestinal cell line Caco-2. | 1996 | Eur. J. Clin. Invest. | pmid:8682162 |
Whiteley LO et al. | Evaluation in rats of the dose-response relationship among colonic mucosal growth, colonic fermentation, and dietary fiber. | 1996 | Dig. Dis. Sci. | pmid:8689925 |
Park C et al. | Differential expression and butyrate response of human alkaline phosphatase genes are mediated by upstream DNA elements. | 1996 | Biochemistry | pmid:8703954 |
Rafferty SP et al. | Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line. | 1996 | Blood | pmid:8704216 |
Sharma JP et al. | Reversed-phase high-performance liquid chromatographic determination of tetracyclines in urine and plasma. | 1977 | J. Chromatogr. | pmid:870510 |
Rivero JA and Adunyah SE | Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8713125 |
Olivieri NF | Reactivation of fetal hemoglobin in patients with beta-thalassemia. | 1996 | Semin. Hematol. | pmid:8714583 |
Eftimiadi C et al. | Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. | 1995 | Minerva Stomatol | pmid:8721203 |
Adams FS et al. | Characterization and transplantation of two neuronal cell lines with dopaminergic properties. | 1996 | Neurochem. Res. | pmid:8726972 |
Madesh M et al. | Butyrate-induced alteration in lipid composition of human colon cell line HT-29. | 1996 | Biochem. Mol. Biol. Int. | pmid:8728094 |