butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jones RJ et al. | Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. | 2015 | Bioresour. Technol. | pmid:25898090 |
Sasajima H et al. | Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. | 2015 | Neurotoxicology | pmid:26493152 |
Huang C et al. | Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets. | 2015 | J. Nutr. | pmid:26491121 |
Luo H et al. | Enhancing Butanol Production under the Stress Environments of Co-Culturing Clostridium acetobutylicum/Saccharomyces cerevisiae Integrated with Exogenous Butyrate Addition. | 2015 | PLoS ONE | pmid:26489085 |
Li L et al. | Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. | 2015 | J. Food Sci. | pmid:26256258 |
Bucki R et al. | Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. | 2015 | Antimicrob. Agents Chemother. | pmid:26248361 |
Chen Y et al. | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. | 2015 | Cardiovasc Diabetol | pmid:26245924 |
Wang X et al. | Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway. | 2015 | Sci Rep | pmid:26234821 |
Steckert AV et al. | Effects of sodium butyrate on aversive memory in rats submitted to sepsis. | 2015 | Neurosci. Lett. | pmid:25888815 |
Castino MR et al. | Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats. | 2015 | PLoS ONE | pmid:25880762 |
Ulfina GG et al. | Modulation of post-partum reproductive performance in dairy cows through supplementation of long- or short-chain fatty acids during transition period. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:25879374 |
Shimizu T et al. | Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells. | 2015 | J Physiol Sci | pmid:25544596 |
Tiwari P et al. | Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. | 2015 | Chem. Biol. Interact. | pmid:25478867 |
Pawelka AJ and Huizinga JD | Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25540235 |
Kotantaki P and Mosialos G | The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. | 2016 | Cell Biochem. Funct. | pmid:27570065 |
Ãvila M et al. | Application of high pressure processing for controlling Clostridium tyrobutyricum and late blowing defect on semi-hard cheese. | 2016 | Food Microbiol. | pmid:27554159 |
Walia K et al. | Effect of feeding sodium butyrate in the late finishing period on Salmonella carriage, seroprevalence, and growth of finishing pigs. | 2016 | Prev. Vet. Med. | pmid:27544256 |
Otto A et al. | The protein inventory of Clostridium difficile grown in complex and minimal medium. | 2016 | Proteomics Clin Appl | pmid:27511832 |
Yin F et al. | Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides. | 2016 | PLoS ONE | pmid:27508934 |
Moore JB et al. | The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. | 2016 | Stem Cells | pmid:27501845 |
Lakhter AJ et al. | Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. | 2016 | J. Biol. Chem. | pmid:27539851 |
Hou G et al. | Tetracycline removal and effect on the formation and degradation of extracellular polymeric substances and volatile fatty acids in the process of hydrogen fermentation. | 2016 | Bioresour. Technol. | pmid:27070285 |
Zeng J et al. | Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. | 2016 | Cell Cycle | pmid:27259983 |
Wang A et al. | Sodium butyrate mitigates in vitro ammonia generation in cecal content of laying hens. | 2016 | Environ Sci Pollut Res Int | pmid:27154844 |
Kapuvári B et al. | Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice. | 2016 | Invest New Drugs | pmid:27146514 |
Wu Y et al. | Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. | 2016 | PLoS ONE | pmid:27104860 |
Rivera-Chávez F et al. | Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. | 2016 | Cell Host Microbe | pmid:27078066 |
Lazarova DL and Bordonaro M | Vimentin, colon cancer progression and resistance to butyrate and other HDACis. | 2016 | J. Cell. Mol. Med. | pmid:27072512 |
Zhang J et al. | Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. | 2016 | PLoS ONE | pmid:26784903 |
Cang S et al. | Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. | 2016 | J Hematol Oncol | pmid:26759222 |
Kaczmarek SA et al. | Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. | 2016 | Poult. Sci. | pmid:26740137 |
Jung JM et al. | Pseudo catalytic transformation of volatile fatty acids into fatty acid methyl esters. | 2016 | Bioresour. Technol. | pmid:26720136 |
Xin F et al. | Strategies for production of butanol and butyl-butyrate through lipase-catalyzed esterification. | 2016 | Bioresour. Technol. | pmid:26710347 |
Cibis KG et al. | Isolation of acetic, propionic and butyric acid-forming bacteria from biogas plants. | 2016 | J. Biotechnol. | pmid:26779817 |
Cueno ME and Ochiai K | Re-discovering periodontal butyric acid: New insights on an old metabolite. | 2016 | Microb. Pathog. | pmid:26466516 |
Liu Y et al. | Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27. | 2016 | Food Funct | pmid:27713965 |
Zhang Y et al. | Monitoring Intracellular pH Change with a Genetically Encoded and Ratiometric Luminescence Sensor in Yeast and Mammalian Cells. | 2016 | Methods Mol. Biol. | pmid:27424899 |
Villain H et al. | HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice. | 2016 | Sci Rep | pmid:27270584 |
Zhang Q et al. | Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. | 2016 | Sci Rep | pmid:27264309 |
Xiong H et al. | Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition. | 2016 | Sci Rep | pmid:27230284 |
Anderson NA et al. | Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. | 2016 | Org. Biomol. Chem. | pmid:27226381 |
Subramanian U et al. | Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. | 2016 | Physiol. Genomics | pmid:27199456 |
Vazquez-DeRose J et al. | Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. | 2016 | Brain Struct Funct | pmid:25431268 |
Popp D et al. | The alkaloid gramine in the anaerobic digestion process-inhibition and adaptation of the methanogenic community. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27138201 |
Endesfelder D et al. | Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. | 2016 | Microbiome | pmid:27114075 |
Park MJ and Sohrabji F | The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. | 2016 | J Neuroinflammation | pmid:27905989 |
Gallo A et al. | Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. | 2016 | J. Anim. Sci. | pmid:27898868 |
Estensoro I et al. | Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. | 2016 | PLoS ONE | pmid:27898676 |
Chang MC et al. | Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. | 2016 | PLoS ONE | pmid:27893752 |
Zhang T et al. | Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. | 2016 | Nutrients | pmid:27886121 |