butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Genomic Instability D042822 7 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Phenylketonurias D010661 7 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Teratocarcinoma D018243 7 associated lipids
Dementia, Vascular D015140 7 associated lipids
Constipation D003248 8 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Thalassemia D013789 8 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Hepatoblastoma D018197 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Hyperkinesis D006948 11 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Ketosis D007662 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Acidosis D000138 13 associated lipids
Radiation Injuries D011832 14 associated lipids
Periodontal Diseases D010510 15 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Lymphoma D008223 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
HIV Infections D015658 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Poultry Diseases D011201 21 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Periodontitis D010518 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Angina Pectoris D000787 27 associated lipids
Brain Diseases D001927 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Jones RJ et al. Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. 2015 Bioresour. Technol. pmid:25898090
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Tiwari P et al. Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. 2015 Chem. Biol. Interact. pmid:25478867
Pawelka AJ and Huizinga JD Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25540235
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Lakhter AJ et al. Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. 2016 J. Biol. Chem. pmid:27539851
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Kapuvári B et al. Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice. 2016 Invest New Drugs pmid:27146514
Wu Y et al. Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. 2016 PLoS ONE pmid:27104860
Rivera-Chávez F et al. Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. 2016 Cell Host Microbe pmid:27078066
Lazarova DL and Bordonaro M Vimentin, colon cancer progression and resistance to butyrate and other HDACis. 2016 J. Cell. Mol. Med. pmid:27072512
Zhang J et al. Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. 2016 PLoS ONE pmid:26784903
Cang S et al. Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. 2016 J Hematol Oncol pmid:26759222
Kaczmarek SA et al. Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. 2016 Poult. Sci. pmid:26740137
Jung JM et al. Pseudo catalytic transformation of volatile fatty acids into fatty acid methyl esters. 2016 Bioresour. Technol. pmid:26720136
Xin F et al. Strategies for production of butanol and butyl-butyrate through lipase-catalyzed esterification. 2016 Bioresour. Technol. pmid:26710347
Cibis KG et al. Isolation of acetic, propionic and butyric acid-forming bacteria from biogas plants. 2016 J. Biotechnol. pmid:26779817
Cueno ME and Ochiai K Re-discovering periodontal butyric acid: New insights on an old metabolite. 2016 Microb. Pathog. pmid:26466516
Liu Y et al. Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27. 2016 Food Funct pmid:27713965
Zhang Y et al. Monitoring Intracellular pH Change with a Genetically Encoded and Ratiometric Luminescence Sensor in Yeast and Mammalian Cells. 2016 Methods Mol. Biol. pmid:27424899
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Zhang Q et al. Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. 2016 Sci Rep pmid:27264309
Xiong H et al. Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition. 2016 Sci Rep pmid:27230284
Anderson NA et al. Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. 2016 Org. Biomol. Chem. pmid:27226381
Subramanian U et al. Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. 2016 Physiol. Genomics pmid:27199456
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Endesfelder D et al. Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. 2016 Microbiome pmid:27114075
Park MJ and Sohrabji F The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. 2016 J Neuroinflammation pmid:27905989
Gallo A et al. Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. 2016 J. Anim. Sci. pmid:27898868
Estensoro I et al. Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. 2016 PLoS ONE pmid:27898676
Chang MC et al. Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. 2016 PLoS ONE pmid:27893752
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121