butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Dementia, Vascular D015140 7 associated lipids
Teratocarcinoma D018243 7 associated lipids
Genomic Instability D042822 7 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Phenylketonurias D010661 7 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Constipation D003248 8 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Thalassemia D013789 8 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Hepatoblastoma D018197 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperkinesis D006948 11 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Ketosis D007662 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Acidosis D000138 13 associated lipids
Radiation Injuries D011832 14 associated lipids
Periodontal Diseases D010510 15 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Lymphoma D008223 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
HIV Infections D015658 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Sarcoma 180 D012510 21 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Periodontitis D010518 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Brain Diseases D001927 27 associated lipids
Angina Pectoris D000787 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Moore JB et al. The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. 2016 Stem Cells pmid:27501845
Fialova B et al. Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine. 2016 Oncol. Rep. pmid:27499010
Foote AP and Freetly HC Effect of abomasal butyrate infusion on net nutrient flux across the portal-drained viscera and liver of growing lambs. 2016 J. Anim. Sci. pmid:27482683
Terova G et al. Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. 2016 PLoS ONE pmid:27471849
Jawed K et al. Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. 2016 PLoS ONE pmid:27466817
Hou G et al. Tetracycline removal and effect on the formation and degradation of extracellular polymeric substances and volatile fatty acids in the process of hydrogen fermentation. 2016 Bioresour. Technol. pmid:27070285
Longpré J et al. Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs. 2016 J. Anim. Sci. pmid:27065267
Lazarova DL and Bordonaro M Vimentin, colon cancer progression and resistance to butyrate and other HDACis. 2016 J. Cell. Mol. Med. pmid:27072512
Early JV et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. 2016 Antimicrob. Agents Chemother. pmid:27044545
He B et al. Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. 2016 Animal pmid:27040131
Petry FS et al. Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. 2016 Behav. Brain Res. pmid:27025446
Frycz BA et al. Transcript level of AKR1C3 is down-regulated in gastric cancer. 2016 Biochem. Cell Biol. pmid:27019068
Li H et al. Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. 2016 Brain Res. pmid:27017959
Ng CH and Yang KL Lipase in biphasic alginate beads as a biocatalyst for esterification of butyric acid and butanol in aqueous media. 2016 Enzyme Microb. Technol. pmid:26672465
Han A et al. Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. 2016 J. Cell. Physiol. pmid:26661480
Tiwari P et al. Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. 2016 Biochimie pmid:26655363
Junicke H et al. Kinetic and thermodynamic control of butyrate conversion in non-defined methanogenic communities. 2016 Appl. Microbiol. Biotechnol. pmid:26403924
Ayers LW et al. Changes in dam and pup behavior following repeated postnatal exposure to a predator odor (TMT): A preliminary investigation in Long-Evans rats. 2016 Dev Psychobiol pmid:26394891
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Reddy YS et al. Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. 2016 J Oleo Sci pmid:26666272
Polycarpo GV et al. Effects of lipid sources, lysophospholipids and organic acids in maize-based broiler diets on nutrient balance, liver concentration of fat-soluble vitamins, jejunal microbiota and performance. 2016 Br. Poult. Sci. pmid:27494540
Kim M et al. Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity. 2016 Bioresour. Technol. pmid:27474955
Anderson NA et al. Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. 2016 Org. Biomol. Chem. pmid:27226381
Subramanian U et al. Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. 2016 Physiol. Genomics pmid:27199456
Bastiaansen JA et al. Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. 2016 Sci Rep pmid:27150735
Seki K et al. Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. 2016 Apoptosis pmid:26994613
Vazquez-DeRose J et al. Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. 2016 Brain Struct Funct pmid:25431268
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121
Tochio T et al. An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. 2016 PLoS ONE pmid:27861621
Tian H et al. Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor. 2016 Molecules pmid:27854343
Neis EP et al. Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. 2016 PLoS ONE pmid:27835668
Liangzhan S et al. Effect of substitution of oat hulls for traditional fiber source on digestion and performance of fattening rabbits. 2017 Animal pmid:27821223
Du H et al. Exploring the microbial origins of p-cresol and its co-occurrence pattern in the Chinese liquor-making process. 2017 Int. J. Food Microbiol. pmid:28843121
Wu T et al. Anthocyanins in black rice, soybean and purple corn increase fecal butyric acid and prevent liver inflammation in high fat diet-induced obese mice. 2017 Food Funct pmid:28792056
Berni Canani R et al. Specific Signatures of the Gut Microbiota and Increased Levels of Butyrate in Children Treated with Fermented Cow's Milk Containing Heat-Killed Lactobacillus paracasei CBA L74. 2017 Appl. Environ. Microbiol. pmid:28733284
Pelgrim CE et al. Butyrate Reduces HFD-Induced Adipocyte Hypertrophy and Metabolic Risk Factors in Obese LDLr-/-.Leiden Mice. 2017 Nutrients pmid:28686216
Yan H and Ajuwon KM Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. 2017 PLoS ONE pmid:28654658
Batlle-Vilanova P et al. Microbial electrosynthesis of butyrate from carbon dioxide: Production and extraction. 2017 Bioelectrochemistry pmid:28633067
Asquith M et al. Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis. 2017 pmid:28622455
Lucchetti D et al. Differentiation Affects the Release of Exosomes from Colon Cancer Cells and Their Ability to Modulate the Behavior of Recipient Cells. 2017 Am. J. Pathol. pmid:28619275
Lu N et al. Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells. 2017 J. Steroid Biochem. Mol. Biol. pmid:28602959
Kumar P et al. Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. 2017 Am. J. Physiol. Renal Physiol. pmid:28566502
Yoo M et al. Metabolic flexibility of a butyrate pathway mutant of Clostridium acetobutylicum. 2017 Metab. Eng. pmid:28159643
Chen C et al. Use of Acetate, Propionate, and Butyrate for Reduction of Nitrate and Sulfate and Methanogenesis in Microcosms and Bioreactors Simulating an Oil Reservoir. 2017 Appl. Environ. Microbiol. pmid:28130297
Zhang L et al. Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice. 2017 J. Cell. Biochem. pmid:28109123
Cueno ME et al. Periodontal disease level-butyric acid putatively contributes to the ageing blood: A proposed link between periodontal diseases and the ageing process. 2017 Mech. Ageing Dev. pmid:28108180
Moens F et al. Lactate- and acetate-based cross-feeding interactions between selected strains of lactobacilli, bifidobacteria and colon bacteria in the presence of inulin-type fructans. 2017 Int. J. Food Microbiol. pmid:27810444
Dong W et al. Sodium butyrate activates NRF2 to ameliorate diabetic nephropathy possibly via inhibition of HDAC. 2017 J. Endocrinol. pmid:27799462
Zhang K et al. Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. 2017 Appl. Biochem. Biotechnol. pmid:27832512
Wang YQ et al. Enhancement of acetate productivity in a thermophilic (55 °C) hollow-fiber membrane biofilm reactor with mixed culture syngas (H/CO) fermentation. 2017 Appl. Microbiol. Biotechnol. pmid:28110397