butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gruchlik A et al. | Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. | Acta Pol Pharm | pmid:21229889 | |
Kien CL et al. | Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. | JPEN J Parenter Enteral Nutr | pmid:18165447 | |
Nabandith V et al. | Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. | Asian Pac. J. Cancer Prev. | pmid:15546251 | |
Usenko TN et al. | [Transformation with the E1A + cHa-ras oncogenes enhances the trans-repressor function of the Elk-1 transcription factor]. | Mol. Biol. (Mosk.) | pmid:12391846 | |
Fathallah H et al. | Epigenetic analysis of the human alpha- and beta-globin gene clusters. | Blood Cells Mol. Dis. | pmid:18029204 | |
Gruchlik A et al. | EFFECTS OF 300 mT STATIC MAGNETIC FIELD ON IL-8 SECRETION IN NORMAL HUMAN COLON MYOFIBROBLASTS. | Acta Pol Pharm | pmid:26647628 | |
Varel VH et al. | Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. | J. Environ. Qual. | pmid:20830936 | |
Sarmiento-Rubiano LA et al. | Dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine. | Res. Microbiol. | pmid:17825531 | |
Durdux M et al. | Fluorescence-based assessment of LRP activity: a comparative study. | Anticancer Res. | pmid:15161018 | |
Mangian HF and Tappenden KA | Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. | JPEN J Parenter Enteral Nutr | pmid:19892901 | |
Jung JW et al. | Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. | Antioxid. Redox Signal. | pmid:16356138 | |
Jeon JH et al. | Characterization and its potential application of two esterases derived from the arctic sediment metagenome. | Mar. Biotechnol. | pmid:18814017 | |
Liamleam W and Annachhatre AP | Electron donors for biological sulfate reduction. | Biotechnol. Adv. | pmid:17572039 | |
Karna E et al. | The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. | Acta Pol Pharm | pmid:19719045 | |
Miki Y et al. | Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. | Anticancer Res. | pmid:17595767 | |
Rahman M et al. | The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. | Oxid Med Cell Longev | pmid:20716918 | |
Mackie RI et al. | Biochemical and microbiological evidence for fermentative digestion in free-living land iguanas (Conolophus pallidus) and marine iguanas (Amblyrhynchus cristatus) on the Galápagos archipelago. | Physiol. Biochem. Zool. | pmid:15057723 | |
Shahbazfar AA et al. | A survey on anticancer effects of artemisinin, iron, miconazole, and butyric acid on 5637 (bladder cancer) and 4T1 (Breast cancer) cell lines. | J Cancer Res Ther | pmid:25579554 | |
Karna E et al. | The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. | Acta Pol Pharm | pmid:19645322 | |
Tekucheva DN et al. | Immobilized purple bacteria for light-driven H2 production from starch and potato fermentation effluents. | Biotechnol. Prog. | pmid:21751433 | |
Orchel A et al. | Quantification of p21 gene expression in Caco-2 cells treated with sodium butyrate using real-time reverse transcription-PCR (RT-PCR) assay. | Acta Pol Pharm | pmid:13678314 | |
Wang L et al. | Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway. | J. Int. Med. Res. | pmid:19589263 | |
Chin HL et al. | Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. | Biotechnol. Prog. | pmid:12675576 | |
Rossi DL et al. | A new mammalian host cell with enhanced survival enables completely serum-free development of high-level protein production cell lines. | Biotechnol. Prog. | pmid:21473000 | |
Han L et al. | Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. | Blood Cells Mol. Dis. | pmid:18555711 | |
Cai G et al. | Metabolic flux network and analysis of fermentative hydrogen production. | Biotechnol. Adv. | pmid:21362466 | |
Taylor AJ and Beck CW | Histone deacetylases are required for amphibian tail and limb regeneration but not development. | Mech. Dev. | pmid:22947425 | |
Zhang S et al. | Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. | J. Food Sci. | pmid:21535640 | |
Rodriguez J et al. | Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions. | Biotechnol. Prog. | pmid:15903237 | |
Hu YC et al. | Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. | Biotechnol. Prog. | pmid:12675574 | |
Liu L et al. | Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:22698927 | |
Sandmann G | A nitromethane-based HPLC system alternative to acetonitrile for carotenoid analysis of fruit and vegetables. | Phytochem Anal | pmid:20310077 | |
Sanduja S et al. | The roles of TTP and BRF proteins in regulated mRNA decay. | Wiley Interdiscip Rev RNA | pmid:21278925 | |
Krokowicz L et al. | Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea: a randomized prospective study. | Travel Med Infect Dis | pmid:24063909 | |
pmid:11071567 | ||||
Barker HA et al. | The Synthesis of Butyric and Caproic Acids from Ethanol and Acetic Acid by Clostridium Kluyveri. | 1945 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16588706 |
TOBIE WC and AYRES GB | alpha-Hydroxyisobutyric acid buffers (pH 2.3-5.0) not altered in pH by mold growth. | 1945 | J. Bacteriol. | pmid:21005569 |
VISSCHER FE | Renal clearance of beta-hydroxybutyric acid in a dog. | 1945 | Proc. Soc. Exp. Biol. Med. | pmid:21006321 |
AXELROD AE et al. | The differential effect of biotin sulfone and gamma-(3,4-ureylenecyclohexyl) butyric acid upon the microbiological activity of biotin and oxybiotin. | 1946 | J. Biol. Chem. | pmid:20985652 |
RABE RF | Butyric acid and duodenal ulcer. | 1946 | J Am Inst Homeopath | pmid:20988470 |
WILLIAMSON J and LOURIE EM | Interference with the trypanocidal action of gamma-(p-arsenosophenyl) butyric acid by p-aminobenzoic acid. | 1946 | Ann Trop Med Parasitol | pmid:20997909 |
TOBIE WC and AYRES GB | Action of alpha-hydroxyisobutyric acid on micro-organisms. | 1946 | Nature | pmid:21064937 |
HARTELIUS V and JOHANSEN G | The influence of alpha, gamma-dihydroxy-beta, beta-dimethyl-butyric acid on yeast growth. | 1946 | Cr Trav Lab Carlsberg Ser Physiol | pmid:21028375 |
LIFSON N and LORBER V | Pathways of conversion of butyrate carbon to rat liver glycogen. | 1947 | Fed. Proc. | pmid:20342751 |
MASON LS and ROBINSON AL | The heats of dilution of aqueous solutions of four amino butyric acids at 25 degrees. | 1947 | J. Am. Chem. Soc. | pmid:20292475 |
WALTER M | [Not Available]. | 1947 | Z Vitam Forsch | pmid:20296102 |
Bhat JV and Barker HA | Clostridium lacto-acetophilum Nov. Spec. and the Role of Acetic Acid in the Butyric Acid Fermentation of Lactate. | 1947 | J. Bacteriol. | pmid:16561372 |
ROBERTS S and SZEGO CM | The influence of fasting on the peripheral utilization of sodium beta-hydroxybutyrate in the rat. | 1947 | Fed. Proc. | pmid:20244242 |
LACKEY RW et al. | Effect on cardiac glycogen of intravenously administered sodium acetoacetate, sodium beta-hydroxybutyrate and sodium butyrate. | 1947 | Proc. Soc. Exp. Biol. Med. | pmid:18921782 |
CLARK FM and DEHR A | A study of butyric acid-producing anaerobes isolated from spoiled canned tomatoes. | 1947 Mar-Apr | Food Res | pmid:20294337 |