butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Littlefield BA and Cidlowski JA | Increased steroid responsiveness during sodium butyrate-induced "differentiation" of HeLa S3 cells. | 1984 | Endocrinology | pmid:6690292 |
Reeves R and Candido EP | Turnover of histone acetyl groups in cultured cells is inhibited by sodium butyrate. | 1978 | FEBS Lett. | pmid:668901 |
Müllner E et al. | Increased levels of dihydrofolate reductase mRNA can be measured in normal, growth-stimulated mouse fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6688360 |
Okabe-Kado J et al. | Effects of inducers of erythroid differentiation of human leukemia K562 cells on vincristine-resistant K562/VCR cells. | 1983 | Leuk. Res. | pmid:6684716 |
Derr RF et al. | Suppression of an ethanol withdrawal syndrome in rats by butyrate, lactate and beta-hydroxybutyrate. | 1983 | Life Sci. | pmid:6682922 |
Candido EP et al. | Sodium butyrate inhibits histone deacetylation in cultured cells. | 1978 | Cell | pmid:667927 |
Okuno E et al. | Effect of chronic administration of riboflavin 2',3',4',5'-tetrabutyrate on the hepatic enzymes of fatty acid oxidation in the rat. | 1983 | J. Nutr. Sci. Vitaminol. | pmid:6676446 |
Edwards MK et al. | Induced muscle differentiation in an embryonal carcinoma cell line. | 1983 | Mol. Cell. Biol. | pmid:6656767 |
Reznikov AG | [Determination of progesterone and delta 4-pregnen-20 alpha-ol-3-one contents in ovaries with two-dimensional thin-layer chromatography and spectrofluorimetry]. | 1978 May-Jun | Ukr. Biokhim. Zh. | pmid:664052 |
Awad WM et al. | Evidence for direct methyl transfer in betaine: homocysteine S-methyl-transferase. | 1983 | J. Biol. Chem. | pmid:6630207 |
Hirano H et al. | Studies on the riboflavin-binding capacity of the rat lens. | 1983 | Int J Vitam Nutr Res | pmid:6629663 |
Reboulleau CP and Shapiro HS | Chemical inducers of differentiation cause conformational changes in the chromatin and deoxyribonucleic acid of murine erythroleukemia cells. | 1983 | Biochemistry | pmid:6626512 |
Loidl P et al. | Lack of correlation between histone H4 acetylation and transcription during the Physarum cell cycle. | 1983 Sep 29-Oct 5 | Nature | pmid:6621695 |
Rao VJ and Hart R | Tool mark determination in cartilage of stabbing victim. | 1983 | J. Forensic Sci. | pmid:6619784 |
D'Anna JA et al. | Extent of histone modifications and H1(0) content during cell cycle progression in the presence of butyrate. | 1983 | Exp. Cell Res. | pmid:6617774 |
Halleck MS and Schlegel RA | C-banding of Peromyscus constitutive heterochromatin persists following histone hyperacetylation. | 1983 | Exp. Cell Res. | pmid:6617770 |
Smerdon MJ | Rearrangements of chromatin structure in newly repaired regions of deoxyribonucleic acid in human cells treated with sodium butyrate or hydroxyurea. | 1983 | Biochemistry | pmid:6615781 |
Stoner GD et al. | Explant culture of human peripheral lung. I. Metabolism of benzo[alpha]pyrene. | 1978 | Lab. Invest. | pmid:661225 |
Ravid A et al. | Inhibition of phorbol ester-mediated interleukin-2 production by cellular differentiating agents. | 1983 | Cancer Res. | pmid:6604573 |
Nozawa S et al. | Sodium butyrate produces concordant expression of "early placental" alkaline phosphatase, pregnancy-specific beta 1-glycoprotein and human chronic gonadotropin beta-subunit in a newly established uterine cervical cancer cell line (SKG-IIIa). | 1983 | Int. J. Cancer | pmid:6604031 |
Targowski SP and Klucinski W | Reduction in mitogenic response of bovine lymphocytes by ketone bodies. | 1983 | Am. J. Vet. Res. | pmid:6603180 |
Heard JM et al. | Autocrine function of murine F-MuLV induced myeloblastic cell lines. | 1983 | Int. J. Cancer | pmid:6600723 |
Ohlsson-Wilhelm BM et al. | K562 human erythroleukemia cell variants resistant to growth inhibition by butyrate have deficient histone acetylation. | 1984 | Am. J. Hum. Genet. | pmid:6595945 |
Leiter JM et al. | Increase in histone acetylation and transitions in histone variants during Friend cell differentiation. | 1984 | Exp. Cell Res. | pmid:6593226 |
Fuchs O et al. | Effect of hemin on poly (A)-containing RNA synthesis and transport from nucleus into cytoplasm in Friend cells of the Fw line. | 1984 | Biomed. Biochim. Acta | pmid:6593067 |
Irving CC et al. | Comparative carcinogenicity of N-butyl-N-(3-carboxypropyl)-nitrosamine and N-butyl-N-(4-hydroxybutyl)nitrosamine for the urinary bladder of (C57BL/6 X DBA/2)F1 mice. | 1984 | J. Natl. Cancer Inst. | pmid:6590920 |
Kyritsis A et al. | Effects of butyrate, retinol, and retinoic acid on human Y-79 retinoblastoma cells growing in monolayer cultures. | 1984 | J. Natl. Cancer Inst. | pmid:6590911 |
Garrè C et al. | Regulation of acetylcholinesterase expression in the K-562 cell line. | 1984 | Cancer Res. | pmid:6589044 |
Yoneda T et al. | Sodium butyrate (SB) augments the effects of 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6588971 |
Singh MK and Yu J | Accumulation of a heat shock-like protein during differentiation of human erythroid cell line K562. | 1984 Jun 14-20 | Nature | pmid:6587191 |
Grosso LE and Pitot HC | The expression of the myc proto-oncogene in a dimethylsulfoxide resistant HL-60 cell line. | 1984 | Cancer Lett. | pmid:6583000 |
Potter GK et al. | Nude mice as models for human leukemia studies. | 1984 | Am. J. Pathol. | pmid:6582788 |
Levenson R et al. | Ionic regulation of MEL cell commitment. | 1983 | J. Cell. Biochem. | pmid:6575972 |
Villeval JL et al. | Erythroid properties of K562 cells. Effect of hemin, butyrate and TPA induction. | 1983 | Exp. Cell Res. | pmid:6575918 |
Reboulleau CP et al. | Maintenance of DNA integrity during murine erythroleukemia cell differentiation induced by ethionine and other hypomethylation agents. | 1983 | Biochim. Biophys. Acta | pmid:6574790 |
Zucker RM et al. | Differentiation of HL-60 cells: cell volume and cell cycle changes. | 1983 | Cytometry | pmid:6574016 |
Zucker RM et al. | The effect of glutathione on HL-60 treated with dimethylsulfoxide, butyric acid or 12-O-tetradecanoylphorbol-13-acetate. | 1983 | FEBS Lett. | pmid:6573264 |
Simpson RT | Structure of chromatin containing extensively acetylated H3 and H4. | 1978 | Cell | pmid:657272 |
Novogrodsky A et al. | Effect of polar organic compounds on leukemic cells. Butyrate-induced partial remission of acute myelogenous leukemia in a child. | 1983 | Cancer | pmid:6571794 |
Novak M and Salemink CA | A model experiment in the study of cocaine base smoking. Isolation of methyl 4-(3-pyridyl) butyrate from cocaine pyrolysate. | 1984 Apr-Jun | Bull Narc | pmid:6569824 |
Tampier L et al. | Biological similarities and differences between rats genetically different in alcohol preference. | 1984 | Alcohol Alcohol. | pmid:6542407 |
Chou JY and Ito F | Regulation of alkaline phosphatase gene expression in cultured placental cells. | 1984 | Prog. Clin. Biol. Res. | pmid:6542217 |
Boyd AW and Metcalf D | Induction of differentiation in HL60 leukaemic cells: a cell cycle dependent all-or-none event. | 1984 | Leuk. Res. | pmid:6538251 |
Inoue T et al. | [A nationwide survey on the use of organic solvents in Japan]. | 1984 | Sangyo Igaku | pmid:6536775 |
Cross TA et al. | Ketogenesis in the living rat followed by 13C NMR spectroscopy. | 1984 | Biochemistry | pmid:6529555 |
Abe M and Kufe DW | Effect of sodium butyrate on human breast carcinoma (MCF-7) cellular proliferation, morphology, and CEA production. | 1984 | Breast Cancer Res. Treat. | pmid:6518293 |
Leibovitch MP et al. | Effect of sodium butyrate on gene expression in a rat myogenic cell line. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6517941 |
Mekler VM et al. | [The use of the annihilated delayed fluorescence phenomenon in the study of the structural organization of the sarcoplasmic reticulum]. | 1984 Sep-Oct | Biofizika | pmid:6509099 |
Jürgens U et al. | Systematic comparison of three basic methods of sample pretreatment for high-performance liquid chromatographic analysis of antiepileptic drugs using gas chromatography as a reference method. | 1984 | Ther Drug Monit | pmid:6506141 |
Dierickx PJ | In vitro binding of butyric acid and crotonic acid by the soluble glutathione S-transferases from rat liver. | 1984 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:6505381 |
Kam WK et al. | The expression of alkaline phosphatases in human gastrointestinal and pancreatic tissues and cell lines. | 1984 | Prog. Clin. Biol. Res. | pmid:6504927 |
Kline LN and DeLuca TJ | A clinical study of CAB lens wear. | 1978 | J Am Optom Assoc | pmid:649911 |
Gill M et al. | Simulation of the metabolism of absorbed energy-yielding nutrients in young sheep. | 1984 | Br. J. Nutr. | pmid:6498153 |
Gullans SR et al. | Stimulation of phosphate transport in the proximal tubule by metabolic substrates. | 1984 | Am. J. Physiol. | pmid:6496686 |
Brazy PC et al. | Interactions between phosphate and oxidative metabolism in proximal renal tubules. | 1984 | Am. J. Physiol. | pmid:6496685 |
Boffa LC et al. | Suppression of histone deacetylation in vivo and in vitro by sodium butyrate. | 1978 | J. Biol. Chem. | pmid:649576 |
Jeng I | Induction of retinol esterification in retinal pigment epithelial cells by butyrate. | 1984 | Life Sci. | pmid:6493006 |
Vanĕk Z et al. | Optimization of streptomycete strains producing polyether and macrolide antibiotics. | 1984 | Biochem. Soc. Trans. | pmid:6489588 |
Burgess EA et al. | Inducibility of heat shock polypeptides in cells containing hyperacetylated histones. | 1984 | Exp. Cell Res. | pmid:6489461 |
Scherz H | [The analysis of polysaccharides used as food additives. VIII. Simple qualitative and semiquantitative procedures for the determination of alginates in food]. | 1984 | Z Lebensm Unters Forsch | pmid:6485554 |
Aiello RJ et al. | Hepatic gluconeogenic and ketogenic interrelationships in the lactating cow. | 1984 | J. Dairy Sci. | pmid:6480960 |
Wagenmakers AJ and Veerkamp JH | Interaction of octanoate with branched-chain 2-oxo acid oxidation in rat and human muscle in vitro. | 1984 | Int. J. Biochem. | pmid:6479435 |
Wong M and Smulson M | A relationship between nuclear poly(adenosine diphosphate ribosylation) and acetylation posttranslational modifications. 2. Histone studies. | 1984 | Biochemistry | pmid:6477891 |
Grunicke H et al. | Depression of histone acetylation by alkylating antitumor agents: significance for antitumor activity and possible biological consequences. | 1984 | Adv. Enzyme Regul. | pmid:6475641 |
Pani B et al. | Sodium butyrate affects the cytotoxic and mutagenic response of V79 Chinese hamster cells to the genotoxic agents, daunorubicin and U.V. radiation. | 1984 | Mutat. Res. | pmid:6472326 |
Horiuchi K et al. | Histone acetylation and deacetylation of nuclei from sea urchin Hemicentrotus pulcherrimus embryos during early stages of development. | 1984 | J. Exp. Zool. | pmid:6470651 |
Matsui I et al. | Effect of sodium butyrate on induction of ornithine decarboxylase activity in phytohemagglutinin-stimulated lymphocytes. | 1984 | Chem. Biol. Interact. | pmid:6467454 |
Abe M and Kufe DW | Sodium butyrate induction of milk-related antigens in human MCF-7 breast carcinoma cells. | 1984 | Cancer Res. | pmid:6467212 |
Embree J et al. | Nonspecific vaginitis among women attending a sexually transmitted diseases clinic. | 1984 Apr-Jun | Sex Transm Dis | pmid:6463811 |
Loidl P et al. | RNA polymerase activity and template activity of chromatin after butyrate induced hyperacetylation of histones in Physarum. | 1984 | Nucleic Acids Res. | pmid:6462909 |
Saffer JD and Glazer RI | The phosphorylation of high mobility group proteins 14 and 17 and their distribution in chromatin. | 1982 | J. Biol. Chem. | pmid:6461658 |
Sterner R et al. | Studies of acetylation and deacetylation in high mobility group proteins. Identification of the sites of acetylation in high mobility group proteins 14 and 17. | 1981 | J. Biol. Chem. | pmid:6455433 |
Minder HP et al. | In vitro fermentation of feces from normal and chronically diarrheal horses. | 1980 | Am. J. Vet. Res. | pmid:6447466 |
Kelly S et al. | Metabolic pathways coupled to H+ transport in turtle urinary bladder. | 1980 | J. Membr. Biol. | pmid:6446607 |
Ichikawa N et al. | Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate. | 1984 | Biken J | pmid:6443174 |
Ros M et al. | Fatty acyl-CoAs as feedback regulators of hexose monophosphate shunt in rat adipocytes. | 1984 | Mol. Cell. Biochem. | pmid:6436683 |
Palmer TN et al. | Can isolated spans of the tricarboxylic acid cycle operate independently? L-proline, oleate and butyrate metabolism in rat hepatocytes. | 1983 | Biochem. Int. | pmid:6435625 |
Spiro RC et al. | Enhanced Ii expression after n-butyrate treatment of a P3HR-1 Burkitt's lymphoma subline which does not express HLA-D. | 1984 Jul-Sep | Hematol Oncol | pmid:6434395 |
Thorgeirsson UP et al. | Protein synthesis but not DNA synthesis is required for tumor cell invasion in vitro. | 1984 | Invasion Metastasis | pmid:6429083 |
Chapman AG et al. | Anticonvulsant activity of intracerebroventricularly administered valproate and valproate analogues. A dose-dependent correlation with changes in brain aspartate and GABA levels in DBA/2 mice. | 1984 | Biochem. Pharmacol. | pmid:6428419 |
Fausnaugh JL et al. | High-performance hydrophobic interaction chromatography of proteins. | 1984 | Anal. Biochem. | pmid:6428267 |
Beck U et al. | The ketogenic effect of glucose in rumen epithelium of ovine (Ovis aries) and bovine (Bos taurus) origin. | 1984 | Comp. Biochem. Physiol., B | pmid:6425008 |
Melzig M and Teuscher E | [Effect of blood factors on the myosin content of cultured vascular smooth muscle cells]. | 1983 | Acta Histochem. | pmid:6421075 |
Roediger WE et al. | Sodium absorption with bacterial fatty acids and bile salts in the proximal and distal colon as a guide to colonic resection. | 1984 | Dis. Colon Rectum | pmid:6418493 |
Jarvis BD et al. | The role of carbonate in the metabolism of glucose by Butyrivibrio fibrisolvens. | 1978 | J. Gen. Microbiol. | pmid:641526 |
Guezennec CY et al. | Metabolic and hormonal response to short term fasting after endurance training in the rat. | 1984 | Horm. Metab. Res. | pmid:6392054 |
Feingold V et al. | Effect of contact material on vibration-induced insulin aggregation. | 1984 | Diabetologia | pmid:6389243 |
Plewa MJ et al. | An evaluation of the genotoxic properties of herbicides following plant and animal activation. | 1984 | Mutat. Res. | pmid:6377060 |
Hoberg KA et al. | Inhibitory effect of cerulenin and sodium butyrate on germination of Candida albicans. | 1983 | Antimicrob. Agents Chemother. | pmid:6357077 |
Tabilio A et al. | Myeloid and megakaryocytic properties of K-562 cell lines. | 1983 | Cancer Res. | pmid:6349795 |
Scher W and Waxman S | Effects of dexamethasone and phorbol myristate acetate on the induction of differentiation in mouse erythroleukemic cells by dimethyl sulfoxide, proteases, and other compounds. | 1983 | Ann. N. Y. Acad. Sci. | pmid:6349493 |
Goz B et al. | Effect of ethanol on alkaline phosphatase activity in HeLa cells. | 1983 | Alcohol. Clin. Exp. Res. | pmid:6346920 |
Sasaki Y and Takahashi H | Insulin response to secretogogues in sheep exposed to cold. | 1983 | J. Physiol. (Lond.) | pmid:6345757 |
Ito Y et al. | Epstein-Barr virus-activating principle in human semen. | 1984 | Cancer Lett. | pmid:6331637 |
Gullans SR et al. | Interactions between gluconeogenesis and sodium transport in rabbit proximal tubule. | 1984 | Am. J. Physiol. | pmid:6331176 |
Morigaki T et al. | Differential inhibitory effects of retinoic acid on Epstein-Barr virus induction in producer and nonproducer cell lines. | 1984 | Intervirology | pmid:6329997 |
Neame PJ and Acton RT | A simple methodology for the routine production and partial purification of human lymphoblastoid interferon. | 1984 | Adv. Exp. Med. Biol. | pmid:6328906 |
Roediger WE et al. | Colonic bicarbonate output as a test of disease activity in ulcerative colitis. | 1984 | J. Clin. Pathol. | pmid:6327778 |
Dascombe MJ | Evidence that cyclic nucleotides are not mediators of fever in rabbits. | 1984 | Br. J. Pharmacol. | pmid:6326920 |
Jentsch TJ et al. | Effect of bicarbonate, pH, methazolamide and stilbenes on the intracellular potentials of cultured bovine corneal endothelial cells. | 1984 | J. Membr. Biol. | pmid:6325699 |