butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Marshall MO and Knudsen J | Factors influencing the in vitro activity of diacylglycerol acyltransferase from bovine mammary gland and liver towards butyryl-CoA and palmitoyl-CoA. | 1980 | Biochim. Biophys. Acta | pmid:7370285 |
Silva P et al. | Competition between sodium reabsorption and gluconeogenesis in kidneys of steroid-treated rats. | 1980 | Am. J. Physiol. | pmid:7377301 |
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Kitzis A et al. | Effect of sodium butyrate on chromatin structure. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7387680 |
Kaplan BA and Trimber CJ | Corneal response to extended wear of CAB contact lenses in aphakia. | 1980 | Ophthalmology | pmid:7393534 |
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Milhaud P et al. | Sodium butyrate affects expression of fibronectin on CHO cells: specific increase in antibody-complement-mediated cytotoxicity. | 1980 | J. Cell. Physiol. | pmid:7410488 |
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Bode J et al. | Modulation of the nucleosome structure by histone acetylation. | 1980 | Eur. J. Biochem. | pmid:7439155 |
Tamura J et al. | [Studies on toxicity of clobetasone-17-butyrate (II)--chronic toxicity in rats (author's transl)]. | 1980 | J Toxicol Sci | pmid:7452742 |
Daniell E | Cells inhibited by n-butyrate support adenovirus replication. | 1980 | Virology | pmid:7456334 |
Sawicki J et al. | Benzo(a)pyrene metabolism and metabolites binding to DNA in the presence of BHA. | 1980 | Arch. Geschwulstforsch. | pmid:7458578 |
Dexter DL et al. | N,N-dimethylformamide and sodium butyrate modulation of the activities of purine-metabolizing enzymes in cultured human colon carcinoma cells. | 1981 | Cancer Res. | pmid:7459868 |
Roediger WE and Moore A | Effect of short-chaim fatty acid on sodium absorption in isolated human colon perfused through the vascular bed. | 1981 | Dig. Dis. Sci. | pmid:7460712 |
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Awad AB et al. | Prostaglandin synthesis in human cancer cells: influence of fatty acids and butyrate. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480078 |
Klijn N et al. | Identification of Clostridium tyrobutyricum as the causative agent of late blowing in cheese by species-specific PCR amplification. | 1995 | Appl. Environ. Microbiol. | pmid:7487024 |
Berwald-Netter Y et al. | Phenotypic modulation in mouse neuroblastoma cells: the case of acetylcholinesterase. | 1978 | Natl Cancer Inst Monogr | pmid:748757 |
Ranganna K et al. | Sodium butyrate inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7489253 |
Parratt JR et al. | Functional effects of intracellular pH alteration in the human uterus: simultaneous measurements of pH and force. | 1995 | J. Reprod. Fertil. | pmid:7490717 |
Li M et al. | Expression and regulation of glycosyltransferases for N-glycosyl oligosaccharides in fresh human surgical and murine tissues and cultured cell lines. | 1995 | Clin. Sci. | pmid:7493440 |
Hague A and Paraskeva C | The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines. | 1995 | Eur. J. Cancer Prev. | pmid:7496324 |
Johnson IT | Butyrate and markers of neoplastic change in the colon. | 1995 | Eur. J. Cancer Prev. | pmid:7496325 |
Lupton JR | Butyrate and colonic cytokinetics: differences between in vitro and in vivo studies. | 1995 | Eur. J. Cancer Prev. | pmid:7496326 |
GarcÃa-Bermejo L et al. | Modulation of HSP70 and HSP27 gene expression by the differentiation inducer sodium butyrate in U-937 human promonocytic leukemia cells. | 1995 | Leuk. Res. | pmid:7500647 |
Morizane T et al. | Antibody binding to liver cells and cell differentiation state. | 1995 | Adv. Exp. Med. Biol. | pmid:7502756 |
Perry CA et al. | Analysis of nucleosome assembly and histone exchange using antibodies specific for acetylated H4. | 1993 | Biochemistry | pmid:7504954 |
Thurnher M et al. | Differences in the regulation of specific glycosylation in the pathogenesis of paroxysmal nocturnal hemoglobinuria and the Tn-syndrome. | 1994 | Exp. Hematol. | pmid:7509289 |
Van Riper G et al. | Induction, characterization, and functional coupling of the high affinity chemokine receptor for RANTES and macrophage inflammatory protein-1 alpha upon differentiation of an eosinophilic HL-60 cell line. | 1994 | J. Immunol. | pmid:7511665 |
Chen YL and Wu RT | Altered queuine modification of transfer RNA involved in the differentiation of human K562 erythroleukemia cells in the presence of distinct differentiation inducers. | 1994 | Cancer Res. | pmid:7513611 |
Seagrave JC et al. | Responses of salivary acinar cells to intracellular alkalinization. | 1994 | J. Cell. Physiol. | pmid:7514610 |
Tsutsumi T et al. | Reciprocal regulation of alpha-fetoprotein and albumin gene expression by butyrate in human hepatoma cells. | 1994 | Gastroenterology | pmid:7518784 |
Barlow S et al. | Stable expression of heterologous microtubule-associated proteins (MAPs) in Chinese hamster ovary cells: evidence for differing roles of MAPs in microtubule organization. | 1994 | J. Cell Biol. | pmid:7519616 |
Sakamoto Hojo ET et al. | Modulatory effect of sodium butyrate on AluI-induced chromosomal aberrations in CHO cells. | 1994 | Mutat. Res. | pmid:7520973 |
Miyashita T et al. | Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A. | 1994 | FEBS Lett. | pmid:7523197 |
Campain JA et al. | Permissive effect of cyclic AMP and cycloheximide for induction by sodium butyrate of the glycoprotein hormone alpha-subunit gene in choriocarcinoma cells. | 1994 | Cell Growth Differ. | pmid:7527246 |
Crespi F et al. | Melatonin, a hormone monitorable in vivo by voltammetry? | 1994 | Analyst | pmid:7527619 |
Rochette J et al. | Fetal hemoglobin levels in adults. | 1994 | Blood Rev. | pmid:7534152 |
Böhmig GA et al. | Induction of alloantigen-specific hyporesponsiveness in vitro by the short-chain fatty acid N-butyrate. | 1995 | Transplantation | pmid:7539556 |
Kawashima K et al. | Human fibroblasts (KMST-6/RAS cell line) transformed with 60Co gamma-rays and c-Ha-ras oncogene produce a large amount of granulocyte colony-stimulating factor (G-CSF); production is enhanced by cAMP, theophylline, and butyrate. | 1995 | Cell Struct. Funct. | pmid:7540958 |
Grässel S et al. | The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester. | 1995 | Mol. Cell. Biochem. | pmid:7544867 |