butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tsai MH et al. | Effect of platelet activating factor and butyrate on the expression of interleukin-2 receptor alpha in nasopharyngeal carcinoma cells. | 2001 | Int. J. Oncol. | pmid:11605008 |
Gandolfi R et al. | Efficient and selective microbial esterification with dry mycelium of Rhizopus oryzae. | 2001 | J. Biotechnol. | pmid:11604169 |
Combourieu B et al. | Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations. | 2001 | Drug Metab. Dispos. | pmid:11602519 |
Lee YJ et al. | Effect of iron concentration on hydrogen fermentation. | 2001 | Bioresour. Technol. | pmid:11601547 |
Takahashi A et al. | Chloride secretion induced by thermostable direct haemolysin of Vibrio parahaemolyticus depends on colonic cell maturation. | 2001 | J. Med. Microbiol. | pmid:11599736 |
Zhang WL et al. | Induction of heat shock proteins and its effects on glial differentiation in rat C6 glioblastoma cells. | 2001 | Kobe J Med Sci | pmid:11599126 |
Bernhard D et al. | Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. | 2001 | Cell Death Differ. | pmid:11598799 |
Chen Z et al. | Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. | 1999 | Chin. Med. J. | pmid:11593538 |
Kim DY et al. | Biosynthesis of polyhydroxyalkanoate copolyester containing cyclohexyl groups by Pseudomonas oleovorans. | 2001 | Int. J. Biol. Macromol. | pmid:11589966 |
Cummins CL et al. | Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. | 2001 | Pharm. Res. | pmid:11587480 |
Lee GS et al. | Layer-by-layer assembly of zeolite crystals on glass with polyelectrolytes as ionic linkers. | 2001 | J. Am. Chem. Soc. | pmid:11583538 |
Kristensen NB | Rumen microbial sequestration of [2-(13)C]acetate in cattle. | 2001 | J. Anim. Sci. | pmid:11583438 |
Shiau MY et al. | Establishment of a consistent L929 bioassay system for TNF-alpha quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells. | 2001 | Mediators Inflamm. | pmid:11577996 |
Rosignoli P et al. | Protective activity of butyrate on hydrogen peroxide-induced DNA damage in isolated human colonocytes and HT29 tumour cells. | 2001 | Carcinogenesis | pmid:11577008 |
Leng SL et al. | Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. | 2001 | Carcinogenesis | pmid:11577001 |
Lührs H et al. | Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells. | 2001 | Dig. Dis. Sci. | pmid:11575451 |
Yin L et al. | Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. | 2001 | J. Biol. Chem. | pmid:11572859 |
Mohiuddin I et al. | Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma. | 2001 | Cancer Gene Ther. | pmid:11571532 |
Martin C et al. | Comparison of non-tracer and tracer methods for determination of volatile fatty acid production rate in the rumen of sheep fed on two levels of intake. | 2001 | Br. J. Nutr. | pmid:11570985 |
Jung M | Inhibitors of histone deacetylase as new anticancer agents. | 2001 | Curr. Med. Chem. | pmid:11562279 |
Yu HQ and Fang HH | Acidification of mid- and high-strength dairy wastewaters. | 2001 | Water Res. | pmid:11561632 |
Ochiai K et al. | Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557577 |
Kiela PR et al. | Regulation of the rat NHE3 gene promoter by sodium butyrate. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11557515 |
Lal S et al. | Vagal afferent responses to fatty acids of different chain length in the rat. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11557510 |
Shimada N et al. | Alterations of gene expression in endoderm differentiation of F9 teratocarcinoma cells. | 2001 | Mol. Reprod. Dev. | pmid:11553914 |
Shin HS et al. | Performance of UASB reactor treating leachate from acidogenic fermenter in the two-phase anaerobic digestion of food waste. | 2001 | Water Res. | pmid:11547866 |
Khan MR et al. | Antimicrobial activity of Lithocarpus celebicus. | 2001 | Fitoterapia | pmid:11543975 |
Davido DJ et al. | Butyrate and propionate downregulate ERK phosphorylation in HT-29 colon carcinoma cells prior to differentiation. | 2001 | Eur. J. Cancer Prev. | pmid:11535873 |
Dongmo AB et al. | Anti-inflammatory and analgesic properties of the stem bark extracts of Erythrophleum suaveolens (Caesalpiniaceae), Guillemin & Perrottet. | 2001 | J Ethnopharmacol | pmid:11535356 |
Stehle HW et al. | Short-chain carboxylic acids produced by gram-negative anaerobic bacteria can accelerate or delay polymorphonuclear leukocyte apoptosis in vitro. | 2001 | J. Periodontol. | pmid:11525438 |
Benjamin D and Jost JP | Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. | 2001 | Nucleic Acids Res. | pmid:11522830 |
Ren H et al. | Short-chain fatty acids induce intestinal epithelial heat shock protein 25 expression in rats and IEC 18 cells. | 2001 | Gastroenterology | pmid:11522747 |
Kitazono M et al. | Enhanced adenovirus transgene expression in malignant cells treated with the histone deacetylase inhibitor FR901228. | 2001 | Cancer Res. | pmid:11522619 |
Reinhardt D et al. | Post-transcriptional effects of interleukin-3, interferon-gamma, erythropoietin and butyrate on in vitro hemoglobin chain synthesis in congenital hemolytic anemia. | 2001 | Haematologica | pmid:11522534 |
Ugazio E et al. | The effect of formulation and concentration of cholesteryl butyrate solid lipid nanospheres (SLN) on NIH-H460 cell proliferation. | 2001 | Eur J Pharm Biopharm | pmid:11522486 |
Finzer P et al. | Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression. | 2001 | Oncogene | pmid:11521189 |
Witt O et al. | Tumor cell differentiation by butyrate and environmental stress. | 2001 | Cancer Lett. | pmid:11520601 |
Kasuga T | Effect of glutamate analogues on red-green opponent interaction in monkey electroretinograms. | 2001 | Exp. Eye Res. | pmid:11520106 |
Chattopadhyay S et al. | Purification and stabilization of 99mTc-d,l-HMPAO: role of organic extractants. | 2001 | Nucl. Med. Biol. | pmid:11518658 |
Sherfi SA and Hamad SH | Microbiological and biochemical studies on Gergoush fermentation. | 2001 | Int. J. Food Microbiol. | pmid:11518434 |
Walker GE et al. | Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. | 2001 | Endocrinology | pmid:11517158 |
Shankaranarayanan P et al. | Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene. | 2001 | J. Biol. Chem. | pmid:11509556 |
Jørgensen J and Mortensen PB | Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis. | 2001 | Dig. Dis. Sci. | pmid:11508674 |
Ito N et al. | Inhibitory effects of sodium butyrate on proliferation and invasiveness of human glioma cells. | 2001 | Neurosurgery | pmid:11504120 |
Huang P et al. | [Inhibition of the expression of Epstein-Barr virus antigens in vitro by Chinese medicine compound "Dongxia wan"]. | 2000 | Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi | pmid:11503041 |
Nakhoul NL et al. | Ammonium interaction with the epithelial sodium channel. | 2001 | Am. J. Physiol. Renal Physiol. | pmid:11502598 |
Kleessen B et al. | Oligofructose and long-chain inulin: influence on the gut microbial ecology of rats associated with a human faecal flora. | 2001 | Br. J. Nutr. | pmid:11502244 |
Hernandez A et al. | Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis. | 2001 | Surgery | pmid:11490359 |
Clarke KO et al. | Tributyrin, an oral butyrate analogue, induces apoptosis through the activation of caspase-3. | 2001 | Cancer Lett. | pmid:11485828 |
Duquette RA and Wray S | pH regulation and buffering power in gastric smooth muscle. | 2001 | Pflugers Arch. | pmid:11484779 |