butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypothyroidism D007037 32 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Insulinoma D007340 28 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Ketosis D007662 13 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Marek Disease D008380 4 associated lipids
Medulloblastoma D008527 22 associated lipids
Melanoma D008545 69 associated lipids
Myoepithelioma D009208 1 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neuroblastoma D009447 66 associated lipids
Nevus D009506 2 associated lipids
Nose Neoplasms D009669 3 associated lipids
Occupational Diseases D009784 42 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Periodontal Diseases D010510 15 associated lipids
Periodontitis D010518 22 associated lipids
Peritonitis D010538 38 associated lipids
Phenylketonurias D010661 7 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Proctitis D011349 1 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Gabris C et al. Analysis of the key enzymes of butyric and acetic acid fermentation in biogas reactors. 2015 Microb Biotechnol pmid:26086956
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Imai K et al. Involvement of Sp1 in butyric acid-induced HIV-1 gene expression. 2015 Cell. Physiol. Biochem. pmid:26383101
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Bai G et al. Dietary Casein and Soy Protein Isolate Modulate the Effects of Raffinose and Fructooligosaccharides on the Composition and Fermentation of Gut Microbiota in Rats. 2016 J. Food Sci. pmid:27434756
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Su CL et al. Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. 2016 J Psychiatr Res pmid:26921875
Tanaka S et al. Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L. 2016 Appl. Environ. Microbiol. pmid:26921420
Donovan JD et al. Volatile Retention and Morphological Properties of Microencapsulated Tributyrin Varied by Wall Material and Drying Method. 2016 J. Food Sci. pmid:26878682
Wang ZT et al. Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells. 2016 Cell. Signal. pmid:26876786
Zounr RA et al. Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents. 2016 Anal Sci pmid:26860556
Valvassori SS et al. Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. 2016 Psychiatry Res pmid:26654753
Mátis G et al. Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. 2016 J Anim Physiol Anim Nutr (Berl) pmid:26614344
Luceri C et al. Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. 2016 Dig Liver Dis pmid:26607831
Kratsman N et al. Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. 2016 Neuropharmacology pmid:26577018
Heidor R et al. The chemopreventive activity of butyrate-containing structured lipids in experimental rat hepatocarcinogenesis. 2016 Mol Nutr Food Res pmid:26548572
Cueno ME et al. Periodontal disease level-butyric acid amounts locally administered in the rat gingival mucosa induce ER stress in the systemic blood. 2016 Microb. Pathog. pmid:26541671
Sergeev E et al. Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands. 2016 J. Biol. Chem. pmid:26518871
Contreras-Leal E et al. Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines. 2016 Mol. Carcinog. pmid:26331238
Xing X et al. Sodium butyrate protects against oxidative stress in HepG2 cells through modulating Nrf2 pathway and mitochondrial function. 2016 J. Physiol. Biochem. pmid:28600747
Huang H et al. Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. 2016 Cell. Mol. Immunol. pmid:25683610
Martín Juárez J et al. Saccharification of microalgae biomass obtained from wastewater treatment by enzymatic hydrolysis. Effect of alkaline-peroxide pretreatment. 2016 Bioresour. Technol. pmid:27372005
Khairy H et al. The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. 2016 Lett. Appl. Microbiol. pmid:27564089
Kong X et al. Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. 2016 Bioresour. Technol. pmid:26998799
Bencsik R et al. Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. 2016 Stem Cell Res pmid:27591479
Han R et al. Sodium Butyrate Upregulates miR-203 Expression to Exert Anti-Proliferation Effect on Colorectal Cancer Cells. 2016 Cell. Physiol. Biochem. pmid:27771718
Polak U et al. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming. 2016 Stem Cells Dev. pmid:27615158
Chen WS et al. Effects of histone deacetylase inhibitor sodium butyrate on heroin seeking behavior in the nucleus accumbens in rats. 2016 Brain Res. pmid:27742468
Miao W et al. Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2. 2016 Int J Mol Sci pmid:27735862
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