butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jackson SK et al. | Induction of anergy in Th1 cells associated with increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. | 2001 | J. Immunol. | pmid:11145672 |
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Mimura Y et al. | Butyrate increases production of human chimeric IgG in CHO-K1 cells whilst maintaining function and glycoform profile. | 2001 | J. Immunol. Methods | pmid:11150551 |
Ling SC and Griffiths AM | Nutrition in inflammatory bowel disease. | 2000 | Curr Opin Clin Nutr Metab Care | pmid:11151077 |
Binnemans K et al. | Structure and mesomorphism of neodymium(III) alkanoates. | 2000 | Inorg Chem | pmid:11151495 |
Mathas S et al. | Anti-CD20- and B-cell receptor-mediated apoptosis: evidence for shared intracellular signaling pathways. | 2000 | Cancer Res. | pmid:11156427 |
Kitazono M et al. | Construction of gene therapy vectors targeting thyroid cells: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cyclic adenosine 3',5'-monophosphate pathway and demonstration of activity in follicular and anaplastic thyroid carcinoma cells. | 2001 | J. Clin. Endocrinol. Metab. | pmid:11158054 |
Rychkov GY et al. | Interaction of hydrophobic anions with the rat skeletal muscle chloride channel ClC-1: effects on permeation and gating. | 2001 | J. Physiol. (Lond.) | pmid:11158270 |
Kamitani H et al. | Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. | 2001 | Carcinogenesis | pmid:11159758 |
Glinghammar B and Rafter J | Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells. | 2001 | Gastroenterology | pmid:11159881 |
Demary K et al. | Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells. | 2001 | Cancer Lett. | pmid:11163113 |
Linsdell P | Direct block of the cystic fibrosis transmembrane conductance regulator Cl(-) channel by butyrate and phenylbutyrate. | 2001 | Eur. J. Pharmacol. | pmid:11164382 |
Barbosa MJ et al. | Acetate as a carbon source for hydrogen production by photosynthetic bacteria. | 2001 | J. Biotechnol. | pmid:11164959 |
Hirayama A et al. | Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production. | 2001 | Kidney Int. Suppl. | pmid:11168990 |
Wu JT et al. | Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11171632 |
Snyder SE et al. | Radiolabeled cholinesterase substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity. | 2001 | J. Cereb. Blood Flow Metab. | pmid:11176278 |
Martin LJ et al. | Potato and high-amylose maize starches are not equivalent producers of butyrate for the colonic mucosa. | 2000 | Br. J. Nutr. | pmid:11177182 |
Giermasz A et al. | Antitumor activity of tributyrin in murine melanoma model. | 2001 | Cancer Lett. | pmid:11179828 |
Hirakawa T et al. | Metabolism of benzo[A]pyrene and the related enzyme activities in hamster embryo cells. | 1979 | Chem. Biol. Interact. | pmid:111804 |
Taddei A and Rosas-Romero AJ | Bioactivity studies of extracts from Tridax procumbens. | 2000 | Phytomedicine | pmid:11185735 |
Pedersen G et al. | Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNgamma, TNFalpha and IL-1beta on viability, butyrate oxidation and IL-8 secretion. | 2000 | Autoimmunity | pmid:11191284 |
Rajendran VM and Binder HJ | Characterization and molecular localization of anion transporters in colonic epithelial cells. | 2000 | Ann. N. Y. Acad. Sci. | pmid:11193571 |
Kurita-Ochiai T et al. | Butyric-acid-induced apoptosis in murine thymocytes and splenic T- and B-cells occurs in the absence of p53. | 2000 | J. Dent. Res. | pmid:11201044 |
Lee CT et al. | Differential effects of adenovirus-p16 on bladder cancer cell lines can be overcome by the addition of butyrate. | 2001 | Clin. Cancer Res. | pmid:11205911 |
Kanauchi O et al. | Dietary fiber fraction of germinated barley foodstuff attenuated mucosal damage and diarrhea, and accelerated the repair of the colonic mucosa in an experimental colitis. | 2001 | J. Gastroenterol. Hepatol. | pmid:11207896 |
Mandal M et al. | Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells. | 2001 | Gastroenterology | pmid:11208715 |
Kilcawley KN et al. | A survey of lipolytic and glycolytic end-products in commercial Cheddar enzyme-modified cheese. | 2001 | J. Dairy Sci. | pmid:11210051 |
Nishimura N et al. | Plasma cholesterol-lowering effect on rats of dietary fiber extracted from immature plants. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11210115 |
Sowa Y and Sakai T | Butyrate as a model for "gene-regulating chemoprevention and chemotherapy.". | 2000 | Biofactors | pmid:11216497 |
Satyanarayana S et al. | Hypoglycaemic activity of extracts from soft corals of Andaman and Nicobar coasts in rats. | 2000 | Indian J. Exp. Biol. | pmid:11218836 |
Murray SM et al. | In vitro fermentation characteristics of native and processed cereal grains and potato starch using ileal chyme from dogs. | 2001 | J. Anim. Sci. | pmid:11219453 |
Zaharia V et al. | Effects of short chain fatty acids on colonic Na+ absorption and enzyme activity. | 2001 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:11223395 |
Meslin JC et al. | Differential influence of butyrate concentration on proximal and distal colonic mucosa in rats born germ-free and associated with a strain of Clostridium paraputrificum. | 2001 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:11223399 |
Azbar N et al. | Effect of process configuration and substrate complexity on the performance of anaerobic processes. | 2001 | Water Res. | pmid:11228981 |
Jerman JC et al. | Pharmacological characterisation of human 5-HT2 receptor subtypes. | 2001 | Eur. J. Pharmacol. | pmid:11230991 |
Nudelman A et al. | Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases. | 2001 | Eur J Med Chem | pmid:11231050 |
Bras-Gonçalves RA et al. | Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis. | 2001 | Gastroenterology | pmid:11231942 |
Mariadason JM et al. | Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation. | 2001 | Gastroenterology | pmid:11231943 |
Tabuchi Y et al. | Establishment and characterization of a colonic epithelial cell line MCE301 from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. | 2000 | Cell Struct. Funct. | pmid:11235898 |
Caderni G et al. | Slow-release pellets of sodium butyrate do not modify azoxymethane (AOM)-induced intestinal carcinogenesis in F344 rats. | 2001 | Carcinogenesis | pmid:11238196 |
Kurita-Ochiai T et al. | Butyric acid-induced T-cell apoptosis is mediated by caspase-8 and -9 activation in a Fas-independent manner. | 2001 | Clin. Diagn. Lab. Immunol. | pmid:11238216 |
Li X et al. | Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells. | 2001 | Cancer Res. | pmid:11245486 |
Araki Y et al. | Alterations in intestinal microflora, faecal bile acids and short chain fatty acids in dextran sulphate sodium-induced experimental acute colitis in rats. | 2001 | Eur J Gastroenterol Hepatol | pmid:11246608 |
Tsubaki J et al. | Effects of sodium butyrate on expression of members of the IGF-binding protein superfamily in human mammary epithelial cells. | 2001 | J. Endocrinol. | pmid:11250651 |
Heathcote ML et al. | Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units. | 2001 | Chem. Biol. | pmid:11251294 |
Yadava RN and Rathore K | A new cardenolide from the seeds of Terminalia arjuna (W&A). | 2000 | J Asian Nat Prod Res | pmid:11252684 |
Musch MW et al. | SCFA increase intestinal Na absorption by induction of NHE3 in rat colon and human intestinal C2/bbe cells. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11254495 |
Renom G et al. | Simple gas chromatography analysis of faecal butyrate: application to patients at risk of pouchitis. | 2001 | Clin. Chem. Lab. Med. | pmid:11256793 |
Alves MM et al. | Effect of lipids and oleic acid on biomass development in anaerobic fixed-bed reactors. Part I: Biofilm growth and activity. | 2001 | Water Res. | pmid:11257880 |
Dasgupta P et al. | Lipophilization of somatostatin analog RC-160 with long chain fatty acid improves its anti-proliferative activity on human oral carcinoma cells in vitro. | 2000 | Life Sci. | pmid:11261586 |