butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chang G et al. | Dietary Sodium Butyrate Supplementation Reduces High-Concentrate Diet Feeding-Induced Apoptosis in Mammary Cells in Dairy Goats. | 2018 | J. Agric. Food Chem. | pmid:29446933 |
Hidaka M et al. | Three lysophosphatidic acids with a distinct long chain moiety differently affect cell differentiation of human colon epithelial cells to goblet cells. | 2018 | Life Sci. | pmid:29412173 |
da Silva JS et al. | Nutritive value and fermentation quality of palisadegrass and stylo mixed silages. | 2018 | Anim. Sci. J. | pmid:28905506 |
Johnson J et al. | Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice. | 2018 | Neurotoxicology | pmid:28610743 |
Sun H et al. | Effects of addition of Aspergillus oryzae culture and 2-hydroxyl-4-(methylthio) butanoic acid on milk performance and rumen fermentation of dairy cows. | 2017 | Anim. Sci. J. | pmid:27506446 |
Tayebi B et al. | Modulation of microRNAs expression in hematopoietic stem cells treated with sodium butyrate in inducing fetal hemoglobin expression. | 2017 | Artif Cells Nanomed Biotechnol | pmid:26837891 |
Zhang Q et al. | Histone acetylation and reactive oxygen species are involved in the preprophase arrest induced by sodium butyrate in maize roots. | 2017 | Protoplasma | pmid:26781092 |
Kamphayae S et al. | Effects of graded levels of liquid brewer's yeast on chemical composition and fermentation quality in cassava pulp and rice straw-based total mixed ration silage. | 2017 | Anim. Sci. J. | pmid:27611881 |
Gulfam A et al. | Characteristics of lactic acid bacteria isolates and their effect on the fermentation quality of Napier grass silage at three high temperatures. | 2017 | J. Sci. Food Agric. | pmid:27539868 |
Sasajima H et al. | Intranasal Administration of Rotenone to Mice Induces Dopaminergic Neurite Degeneration of Dopaminergic Neurons in the Substantia Nigra. | 2017 | Biol. Pharm. Bull. | pmid:28049942 |
Kurano M et al. | Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. | 2017 | PLoS ONE | pmid:28494002 |
Pant K et al. | Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells. | 2017 | Redox Biol | pmid:28288414 |
Niwińska B et al. | Review: Exogenous butyrate: implications for the functional development of ruminal epithelium and calf performance. | 2017 | Animal | pmid:28193308 |
Jaworska J et al. | The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. | 2017 | J Neuroinflammation | pmid:28187734 |
Qiu Y et al. | Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. | 2017 | In Vitro Cell. Dev. Biol. Anim. | pmid:28127702 |
Tylichová Z et al. | Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation. | 2017 | J. Nutr. Biochem. | pmid:27840291 |
Owusu BY and Klampfer L | Modulation of STAT1-Driven Transcriptional Activity by Histone Deacetylases. | 2017 | Methods Mol. Biol. | pmid:27761828 |
Hrgovic I et al. | Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR-2 protein half-life in part via a VE-cadherin-dependent mechanism. | 2017 | Exp. Dermatol. | pmid:27487811 |
Green AL et al. | Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1. | 2017 | Neuropharmacology | pmid:28743636 |
Pant K et al. | Oxidative stress plays a key role in butyrate-mediated autophagy via Akt/mTOR pathway in hepatoma cells. | 2017 | Chem. Biol. Interact. | pmid:28600122 |
Yang S et al. | Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells. | 2017 | Chem. Res. Toxicol. | pmid:28595002 |
Zapletal O et al. | Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models. | 2017 | Arch. Toxicol. | pmid:27830268 |
Li P et al. | Effect of grape pomace on fermentation quality and aerobic stability of sweet sorghum silage. | 2017 | Anim. Sci. J. | pmid:28485116 |
Anantharaju PG et al. | Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC). | 2017 | PLoS ONE | pmid:29190639 |
Seifrtová M et al. | Haemanthamine alters sodium butyrate-induced histone acetylation, p21 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells. | 2017 | Phytomedicine | pmid:28991639 |
Sałkowska A et al. | Differentiation stage-specific effect of histone deacetylase inhibitors on the expression of RORγT in human lymphocytes. | 2017 | J. Leukoc. Biol. | pmid:28951421 |
Meenongyai W et al. | Effects of forage ensiling and ration fermentation on total mixed ration pH, ruminal fermentation and performance of growing Holstein-Zebu cross steers. | 2017 | Anim. Sci. J. | pmid:28370998 |
Zheng ML et al. | Dynamics of microbial community during ensiling direct-cut alfalfa with and without LAB inoculant and sugar. | 2017 | J. Appl. Microbiol. | pmid:28370869 |
Kihara T et al. | Bacillus cereus-type polyhydroxyalkanoate biosynthetic gene cluster contains R-specific enoyl-CoA hydratase gene. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532241 |
Payandeh S et al. | Probiotic supplementation effects on milk fatty acid profile in ewes. | 2017 | J. Dairy Res. | pmid:28524013 |
Donovan JD et al. | In Vitro Digestion and Fermentation of Microencapsulated Tributyrin for the Delivery of Butyrate. | 2017 | J. Food Sci. | pmid:28485486 |
Zhou Z et al. | Changes of cecal microflora in chickens following Eimeria tenella challenge and regulating effect of coated sodium butyrate. | 2017 | Exp. Parasitol. | pmid:28455119 |
Suo Y et al. | Enhanced butyric acid tolerance and production by Class I heat shock protein-overproducing Clostridium tyrobutyricum ATCC 25755. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:28439766 |
Arriaga JM et al. | Metallothionein 1G promotes the differentiation of HT-29 human colorectal cancer cells. | 2017 | Oncol. Rep. | pmid:28393194 |
Foote AP et al. | Effect of abomasal butyrate infusion on gene expression in the duodenum of lambs. | 2017 | J. Anim. Sci. | pmid:28380531 |
Paiva I et al. | Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage. | 2017 | Hum. Mol. Genet. | pmid:28369321 |
Lynch H et al. | Investigation of in-feed organic acids as a low cost strategy to combat Salmonella in grower pigs. | 2017 | Prev. Vet. Med. | pmid:28364832 |
Fu H et al. | Butyric acid production from lignocellulosic biomass hydrolysates by engineered Clostridium tyrobutyricum overexpressing xylose catabolism genes for glucose and xylose co-utilization. | 2017 | Bioresour. Technol. | pmid:28343058 |
Kataoka N et al. | Butyrate production under aerobic growth conditions by engineered Escherichia coli. | 2017 | J. Biosci. Bioeng. | pmid:28089378 |
Hichino A et al. | Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. | 2017 | J. Biol. Chem. | pmid:28057758 |
Fu H et al. | Metabolic engineering of Clostridium tyrobutyricum for enhanced butyric acid production from glucose and xylose. | 2017 | Metab. Eng. | pmid:28040464 |
Jin X et al. | TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment. | 2017 | Cancer Med | pmid:28033672 |
Dai H et al. | Sodium Butyrate Ameliorates High-Concentrate Diet-Induced Inflammation in the Rumen Epithelium of Dairy Goats. | 2017 | J. Agric. Food Chem. | pmid:28032994 |
Bosmans JW et al. | Comparison of three different application routes of butyrate to improve colonic anastomotic strength in rats. | 2017 | Int J Colorectal Dis | pmid:27942836 |
Johnstone M et al. | Characterization of the Pro-Inflammatory Cytokine IL-1β on Butyrate Oxidation in Colorectal Cancer Cells. | 2017 | J. Cell. Biochem. | pmid:27922186 |
Shirasugi M et al. | Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27914813 |
Yan JK et al. | Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27888107 |
Zhang C et al. | Differential effect of early antibiotic intervention on bacterial fermentation patterns and mucosal gene expression in the colon of pigs under diets with different protein levels. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27913852 |
Chriett S et al. | The histone deacetylase inhibitor sodium butyrate improves insulin signalling in palmitate-induced insulin resistance in L6 rat muscle cells through epigenetically-mediated up-regulation of Irs1. | 2017 | Mol. Cell. Endocrinol. | pmid:27619406 |
Kumar G et al. | Microbial responses to various process disturbances in a continuous hydrogen reactor fed with galactose. | 2017 | J. Biosci. Bioeng. | pmid:27614820 |