butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Briggs S and Freedland RA | Effect of ornithine and lactate on urea synthesis in isolated hepatocytes. | 1976 | Biochem. J. | pmid:1008850 |
Krystosek A and Sachs L | Control of lysozyme induction in the differentiation of myeloid leukemic cells. | 1976 | Cell | pmid:1017012 |
Cai Y et al. | Effect of applying lactic acid bacteria isolated from forage crops on fermentation characteristics and aerobic deterioration of silage. | 1999 | J. Dairy Sci. | pmid:10194670 |
Silvi S et al. | Resistant starch modifies gut microflora and microbial metabolism in human flora-associated rats inoculated with faeces from Italian and UK donors. | 1999 | J. Appl. Microbiol. | pmid:10196757 |
Soldatenkov VA et al. | Sodium butyrate induces apoptosis and accumulation of ubiquitinated proteins in human breast carcinoma cells. | 1998 | Cell Death Differ. | pmid:10200476 |
Bonnotte B et al. | Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate. | 1998 | Cell Death Differ. | pmid:10200499 |
Mitsuhashi H et al. | Pharmacological activities of TEI-8362, a novel inhibitor of human neutrophil elastase. | 1999 | Br. J. Pharmacol. | pmid:10205002 |
Tinel M et al. | Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10215635 |
Cuisset L et al. | Quantitative analysis of histone H1 degrees protein synthesis in HTC cells. | 1999 | Eur. J. Biochem. | pmid:10215874 |
Hara H et al. | Short-chain fatty acids suppress cholesterol synthesis in rat liver and intestine. | 1999 | J. Nutr. | pmid:10222383 |
Hung WC and Chuang LY | Sodium butyrate enhances STAT 1 expression in PLC/PRF/5 hepatoma cells and augments their responsiveness to interferon-alpha. | 1999 | Br. J. Cancer | pmid:10360647 |
Maclean KN et al. | Differential effects of sodium butyrate on the transcription of the human TIS11 family of early-response genes in colorectal cancer cells. | 1998 | Br. J. Biomed. Sci. | pmid:10367403 |
Parodi PW | Conjugated linoleic acid and other anticarcinogenic agents of bovine milk fat. | 1999 | J. Dairy Sci. | pmid:10386321 |
Shah M et al. | Selective and reversible blockage of a fatty acid odour response in the olfactory bulb of the frog (Rana temporaria). | 1999 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:10386790 |
Mandal M et al. | Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403841 |
Haas MJ et al. | Sodium butyrate-mediated induction of the glycoprotein hormone alpha-subunit gene: requirement for continued protein synthesis, identification of a butyrate-responsive element, and inhibition of promoter activation by 2-deoxyglucose. | 1999 | J. Cell. Biochem. | pmid:10404394 |
Wang LS et al. | Expression and up-regulation of interleukin-6 in oesophageal carcinoma cells by n-sodium butyrate. | 1999 | Br. J. Cancer | pmid:10408408 |
Mitomo H et al. | Biosynthesis and characterization of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) produced by Burkholderia cepacia D1. | 1999 | Int. J. Biol. Macromol. | pmid:10408637 |
Kamitani H et al. | Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate. | 1999 | Arch. Biochem. Biophys. | pmid:10415110 |
Yasohara Y et al. | Synthesis of optically active ethyl 4-chloro-3-hydroxybutanoate by microbial reduction. | 1999 | Appl. Microbiol. Biotechnol. | pmid:10422229 |
Prasad KN et al. | Cyclic nucleotides in the regulation of expression of differentiated functions in neuroblastoma cells. | 1976 | J. Natl. Cancer Inst. | pmid:10449 |
Meng S et al. | Short-chain fatty acids and thyroid hormone interact in regulating enterocyte gene transcription. | 1999 | Surgery | pmid:10455897 |
Hurst RD and Clark JB | Butyric acid mediated induction of enhanced transendothelial resistance in an in vitro model blood-brain barrier system. | 1999 | Neurochem. Int. | pmid:10458656 |
Van den Bergh O et al. | Acquisition and extinction of somatic symptoms in response to odours: a Pavlovian paradigm relevant to multiple chemical sensitivity. | 1999 | Occup Environ Med | pmid:10472302 |
Jeanteur P | [Dietary fibre intake and colon cancer]. | 1999 Jul-Aug | Bull Cancer | pmid:10477376 |
Sakata T et al. | Probiotic preparations dose-dependently increase net production rates of organic acids and decrease that of ammonia by pig cecal bacteria in batch culture. | 1999 | Dig. Dis. Sci. | pmid:10489936 |
Wiechmann AF and Burden MA | Regulation of AA-NAT and HIOMT gene expression by butyrate and cyclic AMP in Y79 human retinoblastoma cells. | 1999 | J. Pineal Res. | pmid:10496148 |
Stahl A et al. | Identification of the major intestinal fatty acid transport protein. | 1999 | Mol. Cell | pmid:10518211 |
Jordan NJ et al. | Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells. | 1999 | J. Clin. Invest. | pmid:10525044 |
Guo Z et al. | Secretion of phospholipid transfer protein by human hepatoma cell line, Hep G2, is enhanced by sodium butyrate. | 1999 | J. Nutr. | pmid:10539773 |
Kaiser E et al. | [Investigations on the fermentation quality of silage from low-nitrate green forage]. | 1999 | Arch Tierernahr | pmid:10548978 |
Garrison PM and Denison MS | Analysis of the murine AhR gene promoter. | 2000 | J. Biochem. Mol. Toxicol. | pmid:10561076 |
Tamai I et al. | Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1. | 1999 | J. Pharm. Pharmacol. | pmid:10579682 |
Harris LM et al. | Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: need for new phenomenological models for solventogenesis and butanol inhibition? | 2000 | Biotechnol. Bioeng. | pmid:10581430 |
Pitcher MC et al. | The contribution of sulphate reducing bacteria and 5-aminosalicylic acid to faecal sulphide in patients with ulcerative colitis. | 2000 | Gut | pmid:10601057 |
Simpson EJ et al. | In vivo measurement of colonic butyrate metabolism in patients with quiescent ulcerative colitis. | 2000 | Gut | pmid:10601058 |
Kataoka M et al. | 3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46. | 2000 | Eur. J. Biochem. | pmid:10601844 |
Liu H et al. | Chemo-enzymatic synthesis of the antidepressant duloxetine and its enantiomer. | 2000 | Chirality | pmid:10602263 |
Chai F et al. | Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate. | 2000 | Carcinogenesis | pmid:10607727 |
Crew TE et al. | A cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug enhances the growth inhibitory effect of butyrate in colorectal carcinoma cells expressing COX-2 protein: regulation of COX-2 by butyrate. | 2000 | Carcinogenesis | pmid:10607736 |
Watkins SM et al. | Butyric acid and tributyrin induce apoptosis in human hepatic tumour cells. | 1999 | J. Dairy Res. | pmid:10612054 |
Wu GD et al. | High-level expression of I kappa B-beta in the surface epithelium of the colon: in vitro evidence for an immunomodulatory role. | 1999 | J. Leukoc. Biol. | pmid:10614789 |
Zimmermann N et al. | Molecular analysis of CCR-3 events in eosinophilic cells. | 2000 | J. Immunol. | pmid:10623856 |
Rickard KL et al. | Short-chain fatty acids reduce expression of specific protein kinase C isoforms in human colonic epithelial cells. | 2000 | J. Cell. Physiol. | pmid:10623886 |
Pellizzaro C et al. | Cholesteryl butyrate in solid lipid nanospheres as an alternative approach for butyric acid delivery. | 1999 Sep-Oct | Anticancer Res. | pmid:10628332 |
Faber J et al. | Terminal deoxynucleotidyl transferase-negative acute lymphoblastic leukemia. | 2000 | Arch. Pathol. Lab. Med. | pmid:10629138 |
Barshishat M et al. | Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells. | 2000 | Br. J. Cancer | pmid:10638989 |
Hu Z et al. | Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1. | 2000 | J. Biol. Chem. | pmid:10644769 |
Smith RD et al. | Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. | 2000 | Blood | pmid:10648397 |