butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Lu R et al. Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. 2014 J. Periodont. Res. pmid:25340203
Grousseau E et al. Phosphorus limitation strategy to increase propionic acid flux towards 3-hydroxyvaleric acid monomers in Cupriavidus necator. 2014 Bioresour. Technol. pmid:24365742
Wang C et al. A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. 2014 Anim. Sci. J. pmid:23638801
Unno T et al. Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats. 2014 J. Nutr. Sci. Vitaminol. pmid:25078378
Vidrine K et al. Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. 2014 Obesity (Silver Spring) pmid:23630079
Yu M et al. Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells. 2014 Mol. Carcinog. pmid:23359532
Procentese A et al. Continuous xylose fermentation by Clostridium acetobutylicum--kinetics and energetics issues under acidogenesis conditions. 2014 Bioresour. Technol. pmid:24852648
Kondo Y et al. Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. 2014 PLoS ONE pmid:25084468
Vargas JE et al. Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells. 2014 Biochem. Cell Biol. pmid:25070040
Ozadali K et al. Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. 2014 Bioorg. Med. Chem. Lett. pmid:24631185
Shen H et al. BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. 2014 J. Cell. Mol. Med. pmid:24571310
Karki P et al. Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. 2014 Mol. Cell. Biol. pmid:24469401
Pérez-Carro R et al. Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. 2014 Clin. Genet. pmid:23895425
Jin H et al. Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. 2014 J. Biol. Chem. pmid:25342743
Ferrario C et al. Modulation of fecal Clostridiales bacteria and butyrate by probiotic intervention with Lactobacillus paracasei DG varies among healthy adults. 2014 J. Nutr. pmid:25332478
Gong Q et al. [Sodium butyrate inhibits HMGB1 expression and release and attenuates concanavalin A-induced acute liver injury in mice]. 2014 Sheng Li Xue Bao pmid:25332009
Pal A and Dey J Organogelation by 4-(N-tetradecanoyl)aminohydroxybutyric acids: effect of hydrogen-bonding group in the amphiphile head. 2014 J Phys Chem B pmid:25310731
Lorenzo JM Influence of the type of fiber coating and extraction time on foal dry-cured loin volatile compounds extracted by solid-phase microextraction (SPME). 2014 Meat Sci. pmid:23896153
Lee JM et al. Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. 2014 ChemSusChem pmid:25123894
Lopez CA et al. Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. 2014 Cell Host Microbe pmid:25121745
Cho HJ and Song MJ A gammaherpesvirus establishes persistent infection in neuroblastoma cells. 2014 Mol. Cells pmid:25092213
Li S et al. High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. 2014 J. Anim. Sci. pmid:25085388
Shin J et al. The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. 2014 J. Biol. Chem. pmid:25037223
Weber TE et al. Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. 2014 J. Anim. Sci. pmid:25023805
Nakata S et al. Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. 2014 Int. J. Oncol. pmid:25017791
Gutiérrez Acosta OB et al. Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. 2014 BMC Genomics pmid:25012398
Farkas O et al. Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system. 2014 J. Anim. Sci. pmid:24987069
Yang F et al. Sodium butyrate protects against toxin-induced acute liver failure in rats. 2014 HBPD INT pmid:24919615
Peterson EC and Daugulis AJ The use of high pressure CO2 -facilitated pH swings to enhance in situ product recovery of butyric acid in a two-phase partitioning bioreactor. 2014 Biotechnol. Bioeng. pmid:24888558
Tiwari P and Gupta KP Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. 2014 Toxicol. Appl. Pharmacol. pmid:24792773
Pasvolsky R et al. Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. 2014 Int. J. Food Microbiol. pmid:24801271
Maggio A et al. Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. 2014 Int. J. Radiat. Oncol. Biol. Phys. pmid:24803033
Ellis JT et al. Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. 2014 Can. J. Microbiol. pmid:24898684
Ochiai K and Kurita-Ochiai T [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. 2014 Nippon Yakurigaku Zasshi pmid:25109521
Liu W et al. Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. 2014 Br. J. Nutr. pmid:24774835
Ladirat SE et al. Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. 2014 Br. J. Nutr. pmid:24925303
Krokowicz L et al. Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis--a prospective randomized study. 2014 Int J Colorectal Dis pmid:24343275
Sanchez R et al. Differential abundance of IGF1, bile acids, and the genes involved in their signaling in the dominant follicle microenvironment of lactating cows and nulliparous heifers. 2014 Theriogenology pmid:24503106
Leon Carrion S et al. Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation. 2014 Exp. Dermatol. pmid:24451036
Cueno ME et al. Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease. 2014 Cell Stress Chaperones pmid:24052229
Sabra W et al. Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. 2014 Appl. Microbiol. Biotechnol. pmid:24584460
Blank M et al. Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. 2014 Neurobiol Learn Mem pmid:24583371
Possebom G et al. Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. 2014 J. Sci. Food Agric. pmid:24578290
Zhang Z et al. Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. 2014 Cell Reprogram pmid:24568633
Bolhari B et al. Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. 2014 J Endod pmid:24565666
Ai B et al. Butyric acid fermentation of sodium hydroxide pretreated rice straw with undefined mixed culture. 2014 J. Microbiol. Biotechnol. pmid:24561721
Hong JK et al. Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. 2014 Appl. Microbiol. Biotechnol. pmid:24557571
Liu Y et al. Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. 2014 Biotechnol. Lett. pmid:24557070
Hu X et al. Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. 2014 Dev. Growth Differ. pmid:24494796
Singh V et al. Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia. 2014 Neuroscience pmid:24480366
Rivkin I et al. Cancer cell sensitization and improved treatment efficacy by combined sodium butyrate and paclitaxel formulations is cancer-type specific. 2014 Int J Pharm pmid:24370842
Aoyama Y et al. Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor. 2014 Int. J. Neuropsychopharmacol. pmid:24345457
Khan S and Jena GB Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. 2014 Chem. Biol. Interact. pmid:24530320
Ferreira AC et al. Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. 2014 Ann. Hematol. pmid:24577510
Meehan CJ and Beiko RG A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. 2014 Genome Biol Evol pmid:24625961
Pan Y et al. Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. 2014 Technol. Cancer Res. Treat. pmid:23919394
Molina S et al. Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. 2013 Oct-Nov Chem. Phys. Lipids pmid:23973778
Wu Z et al. Histone deacetylase inhibitors suppress the growth of human osteosarcomas in vitro and in vivo. 2013 Oct-Dec J BUON pmid:24344034
Tigunova EA et al. [Alternative type of fuel--biobutanol]. 2013 Nov-Dec Tsitol. Genet. pmid:24437198
Misaghi S et al. Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production. 2013 May-Jun Biotechnol. Prog. pmid:23596153
Wan S et al. Anaerobic digestion of municipal solid waste composed of food waste, wastepaper, and plastic in a single-stage system: performance and microbial community structure characterization. 2013 Bioresour. Technol. pmid:23974214
Rochus K et al. Highly viscous guar gum shifts dietary amino acids from metabolic use to fermentation substrate in domestic cats. 2013 Br. J. Nutr. pmid:22877608
Cantoni S et al. Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition. 2013 FEBS J. pmid:23463962
Muhammad A et al. Novel fluorescent membrane for metronidazole sensing prepared by covalent immobilization of a pyrenebutyric acid derivative. 2013 J Fluoresc pmid:23471624
Tirandaz H and Mohammadi E Efficient tumor targeting by anaerobic butyrate-producing bacteria. 2013 Med. Hypotheses pmid:23410499
Cuadrado-Tejedor M et al. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. 2013 Curr. Pharm. Des. pmid:23448463
Raybuck JD et al. The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. 2013 Pharmacol. Biochem. Behav. pmid:23454534
Wang HG et al. Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro. 2013 Int. J. Mol. Med. pmid:23440283
Kedia G et al. Addressing the challenge of optimum polyhydroxyalkanoate harvesting: monitoring real time process kinetics and biopolymer accumulation using dielectric spectroscopy. 2013 Bioresour. Technol. pmid:23500571
Fialova B et al. Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines. 2013 Oncol. Rep. pmid:23503510
Ayers LW et al. Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. 2013 Behav. Brain Res. pmid:23831303
Liang X et al. Sodium butyrate protects against severe burn-induced remote acute lung injury in rats. 2013 PLoS ONE pmid:23874764
Wiese BI et al. Short communication: Interrelationship between butyrate and glucose supply on butyrate and glucose oxidation by ruminal epithelial preparations. 2013 J. Dairy Sci. pmid:23810600
Antharam VC et al. Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea. 2013 J. Clin. Microbiol. pmid:23804381
Fujiki R et al. A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons. 2013 Cell Death Dis pmid:23788034
Gałecka M et al. Faecalibacterium prausnitzii and Crohn's disease - is there any connection? 2013 Pol. J. Microbiol. pmid:23829084
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Lim JH et al. Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. 2013 Bioresour. Technol. pmid:23127832
Zhang Z and Wu WS Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. 2013 Stem Cells Dev. pmid:23534850
Coskun T et al. Carbodeoxygenation of biomass: the carbonylation of glycerol and higher polyols to monocarboxylic acids. 2013 Chemistry pmid:23536394
Ximenes JC et al. Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. 2013 Naunyn Schmiedebergs Arch. Pharmacol. pmid:23584602
Stojcev Z et al. Early treatment and prevention of the radiation proctitis--composite enemas containing sodium butyrate. 2013 Int J Colorectal Dis pmid:23516076
Nör C et al. The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells. 2013 Mol. Neurobiol. pmid:23516101
Chen HC et al. Preparation of highly conjugated water-dispersible graphene-butyric acid for the enhancement of electron transfer within polyamic acid-benzoxazole: potential applications in electrochemical sensing. 2013 Biosens Bioelectron pmid:23517822
Yaku K et al. AMPK synergizes with the combined treatment of 1'-acetoxychavicol acetate and sodium butyrate to upregulate phase II detoxifying enzyme activities. 2013 Mol Nutr Food Res pmid:23559539
Itzhak Y et al. Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory. 2013 Neurobiol Learn Mem pmid:23567105
Hao PP et al. Isolation of EpCAM(+)/CD133 (-) hepatic progenitor cells. 2013 Mol. Cells pmid:24293012
Venkataramanan KP et al. The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. 2013 BMC Genomics pmid:24299206
Grousseau E et al. Impact of sustaining a controlled residual growth on polyhydroxybutyrate yield and production kinetics in Cupriavidus necator. 2013 Bioresour. Technol. pmid:24035890
Cuervo A et al. Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. 2013 Nutr Res pmid:24074739
Dükkancı M and Gündüz G Sonolytic degradation of butyric acid in aqueous solutions. 2013 J. Environ. Manage. pmid:24029459
Sánchez-Tena S et al. Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. 2013 Biochim. Biophys. Acta pmid:23994611
Damiani R et al. Enhancement of human thyrotropin synthesis by sodium butyrate addition to serum-free CHO cell culture. 2013 Appl. Biochem. Biotechnol. pmid:23996121
Mattace Raso G et al. Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. 2013 PLoS ONE pmid:23861927
Zhang L et al. Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. 2013 PLoS ONE pmid:23861937
Muhammad SI et al. Upregulation of genes related to bone formation by γ-amino butyric acid and γ-oryzanol in germinated brown rice is via the activation of GABAB-receptors and reduction of serum IL-6 in rats. 2013 Clin Interv Aging pmid:24098073
Maioli M et al. Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment. 2013 Drug Des Devel Ther pmid:24101862
Mu D et al. Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. 2013 PLoS ONE pmid:24086397
Li H et al. Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells. 2013 J Biomol Screen pmid:24163393
Resende WR et al. Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer. 2013 Behav Pharmacol pmid:23994816