| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Diabetic Ketoacidosis | D016883 | 16 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wan S et al. | Anaerobic digestion of municipal solid waste composed of food waste, wastepaper, and plastic in a single-stage system: performance and microbial community structure characterization. | 2013 | Bioresour. Technol. | pmid:23974214 |
| Wei Y et al. | Bioconversion of wheat stalk to hydrogen by dark fermentation: effect of different mixed microflora on hydrogen yield and cellulose solubilisation. | 2011 | Bioresour. Technol. | pmid:21177102 |
| Kyazze G et al. | Direct fermentation of fodder maize, chicory fructans and perennial ryegrass to hydrogen using mixed microflora. | 2008 | Bioresour. Technol. | pmid:18513959 |
| Hu ZH et al. | Application of response surface methodology for optimization of acidogenesis of cattail by rumen cultures. | 2006 | Bioresour. Technol. | pmid:16289873 |
| Jiang L et al. | Butyric acid fermentation in a fibrous bed bioreactor with immobilized Clostridium tyrobutyricum from cane molasses. | 2009 | Bioresour. Technol. | pmid:19297150 |
| Jiang WZ et al. | Improving acidogenic performance in anaerobic degradation of solid organic waste using a rotational drum fermentation system. | 2005 | Bioresour. Technol. | pmid:15978985 |
| Gullón P et al. | Manufacture and prebiotic potential of oligosaccharides derived from industrial solid wastes. | 2011 | Bioresour. Technol. | pmid:21392971 |
| Lim SJ et al. | Anaerobic organic acid production of food waste in once-a-day feeding and drawing-off bioreactor. | 2008 | Bioresour. Technol. | pmid:18502638 |
| Jones RJ et al. | Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. | 2015 | Bioresour. Technol. | pmid:25898090 |
| Chatzifragkou A et al. | Impact of anaerobiosis strategy and bioreactor geometry on the biochemical response of Clostridium butyricum VPI 1718 during 1,3-propanediol fermentation. | 2011 | Bioresour. Technol. | pmid:21967709 |
| Silva FT et al. | Replacement of sugars to hydrogen production by Rhodobacter capsulatus using dark fermentation effluent as substrate. | 2016 | Bioresour. Technol. | pmid:26476167 |
| Turon V et al. | Growth of Chlorella sorokiniana on a mixture of volatile fatty acids: The effects of light and temperature. | 2015 | Bioresour. Technol. | pmid:26461792 |
| Yan Q et al. | Coupling of the hydrogen and polyhydroxyalkanoates (PHA) production through anaerobic digestion from Taihu blue algae. | 2010 | Bioresour. Technol. | pmid:20153165 |
| Cui XH et al. | Production of adventitious roots and secondary metabolites by Hypericum perforatum L. in a bioreactor. | 2010 | Bioresour. Technol. | pmid:20171884 |
| Lateef SA et al. | Biohydrogen production from co-digestion of cow manure and waste milk under thermophilic temperature. | 2012 | Bioresour. Technol. | pmid:22342089 |
| Regestein L et al. | Impact of butyric acid on butanol formation by Clostridium pasteurianum. | 2015 | Bioresour. Technol. | pmid:26233327 |
| Chen CY et al. | Improved phototrophic H2 production with Rhodopseudomonas palustris WP3-5 using acetate and butyrate as dual carbon substrates. | 2008 | Bioresour. Technol. | pmid:17826982 |
| Wijekoon KC et al. | Effect of organic loading rate on VFA production, organic matter removal and microbial activity of a two-stage thermophilic anaerobic membrane bioreactor. | 2011 | Bioresour. Technol. | pmid:21256737 |
| Karthikeyan OP et al. | Hydrolysis-acidogenesis of food waste in solid-liquid-separating continuous stirred tank reactor (SLS-CSTR) for volatile organic acid production. | 2016 | Bioresour. Technol. | pmid:26512860 |
| Sheridan BA et al. | Biofiltration of n-butyric acid for the control of odour. | 2003 | Bioresour. Technol. | pmid:12699941 |
| Redwood MD et al. | Electro-extractive fermentation for efficient biohydrogen production. | 2012 | Bioresour. Technol. | pmid:22225609 |
| Cheong DY and Hansen CL | Feasibility of hydrogen production in thermophilic mixed fermentation by natural anaerobes. | 2007 | Bioresour. Technol. | pmid:17107783 |
| Wong BT and Lee DJ | Denitrifying sulfide removal and carbon methanogenesis in a mesophilic, methanogenic culture. | 2011 | Bioresour. Technol. | pmid:21507619 |
| Vadlani PV and Ramachandran KB | Evaluation of UASB reactor performance during start-up operation using synthetic mixed-acid waste. | 2008 | Bioresour. Technol. | pmid:18439822 |
| Jo JH et al. | The effects of pH on carbon material and energy balances in hydrogen-producing Clostridium tyrobutyricum JM1. | 2008 | Bioresour. Technol. | pmid:18485698 |
| Karadag D et al. | Thermophilic biohydrogen production by an anaerobic heat treated-hot spring culture. | 2009 | Bioresour. Technol. | pmid:19592235 |
| Arslan D et al. | Effect of hydrogen and carbon dioxide on carboxylic acids patterns in mixed culture fermentation. | 2012 | Bioresour. Technol. | pmid:22705528 |
| Dareioti MA et al. | Effect of pH on the anaerobic acidogenesis of agroindustrial wastewaters for maximization of bio-hydrogen production: a lab-scale evaluation using batch tests. | 2014 | Bioresour. Technol. | pmid:24759638 |
| Lee YJ et al. | Effect of iron concentration on hydrogen fermentation. | 2001 | Bioresour. Technol. | pmid:11601547 |
| Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
| Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
| Hwang JH et al. | Feasibility of hydrogen production from ripened fruits by a combined two-stage (dark/dark) fermentation system. | 2011 | Bioresour. Technol. | pmid:20846852 |
| Fei Q et al. | Lipid production by microalgae Chlorella protothecoides with volatile fatty acids (VFAs) as carbon sources in heterotrophic cultivation and its economic assessment. | 2015 | Bioprocess Biosyst Eng | pmid:25332127 |
| Niklas J et al. | Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis. | 2011 | Bioprocess Biosyst Eng | pmid:21188421 |
| Bizukojc M et al. | Metabolic modelling of syntrophic-like growth of a 1,3-propanediol producer, Clostridium butyricum, and a methanogenic archeon, Methanosarcina mazei, under anaerobic conditions. | 2010 | Bioprocess Biosyst Eng | pmid:19680695 |
| Nikhil PE et al. | Clustering hybrid regression: a novel computational approach to study and model biohydrogen production through dark fermentation. | 2008 | Bioprocess Biosyst Eng | pmid:18320232 |
| Tatara M et al. | High-rate thermophilic methane fermentation on short-chain fatty acids in a down-flow anaerobic packed-bed reactor. | 2005 | Bioprocess Biosyst Eng | pmid:15565281 |
| Ra CH et al. | Hyper-thermal acid hydrolysis and adsorption treatment of red seaweed, Gelidium amansii for butyric acid production with pH control. | 2017 | Bioprocess Biosyst Eng | pmid:27878375 |
| Bayramoglu G et al. | Poly(styrene-divinylbenzene) beads surface functionalized with di-block polymer grafting and multi-modal ligand attachment: performance of reversibly immobilized lipase in ester synthesis. | 2011 | Bioprocess Biosyst Eng | pmid:21336640 |
| Shrake A et al. | Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions. | 2006 | Biopolymers | pmid:16273515 |
| O'Donnell JM et al. | Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart. | 2002 | Biophys. J. | pmid:11751291 |
| Yu X et al. | Kinetic analysis of dynamic 13C NMR spectra: metabolic flux, regulation, and compartmentation in hearts. | 1995 | Biophys. J. | pmid:8580353 |
| Zhang Y et al. | Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19041242 |
| Carbone V et al. | Structure-based design of inhibitors of human L-xylulose reductase modelled into the active site of the enzyme. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12668014 |
| Klee N et al. | Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20615694 |
| Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
| Xu H and Zhang JL | Natural products-based insecticidal agents 9. Design, semisynthesis and insecticidal activity of 28-acyloxy derivatives of toosendanin against Mythimna separata Walker in vivo. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21376589 |
| Lash TD et al. | Normal and abnormal heme biosynthesis. Part 7. Synthesis and metabolism of coproporphyrinogen-III analogues with acetate or butyrate side chains on rings C and D. Development of a modified model for the active site of coproporphyrinogen oxidase. | 2011 | Bioorg. Med. Chem. | pmid:21277781 |
| Rubin VN et al. | Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics. | 2001 | Bioorg. Med. Chem. | pmid:11408177 |
| Innocenti A et al. | Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates. | 2009 | Bioorg. Med. Chem. | pmid:19297172 |
| Bora-Tatar G et al. | Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies. | 2009 | Bioorg. Med. Chem. | pmid:19520580 |
| Wimmer Z et al. | Insect pest control agents: Novel chiral butanoate esters (juvenogens). | 2007 | Bioorg. Med. Chem. | pmid:17614289 |
| Roche E et al. | Role of small bioorganic molecules in stem cell differentiation to insulin-producing cells. | 2006 | Bioorg. Med. Chem. | pmid:16797999 |
| Black SL et al. | Probing lipid- and drug-binding domains with fluorescent dyes. | 2008 | Bioorg. Med. Chem. | pmid:18024138 |
| Malawska B et al. | Investigation into new anticonvulsant derivatives of alpha-substituted N-benzylamides of gamma-hydroxy- and gamma-acetoxybutyric acid. Part 5: search for new anticonvulsant compounds. | 2004 | Bioorg. Med. Chem. | pmid:14738973 |
| Pegklidou K et al. | Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole. | 2010 | Bioorg. Med. Chem. | pmid:20189816 |
| Davletshin AI et al. | [Effect of surfactants on peroxidase activity. I. Effect of anionic surfactants]. | 1998 | Bioorg. Khim. | pmid:9702352 |
| Sobolewski C et al. | Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. | 2015 | Biomolecules | pmid:26343742 |
| Tazoe H et al. | Expression of short-chain fatty acid receptor GPR41 in the human colon. | 2009 | Biomed. Res. | pmid:19574715 |
| Horton MA | Analysis of marker enzymes in the K562 erythroleukaemia cell line: no coordinate expression of red cell enzymes on induction of haemoglobin synthesis. | 1982 | Biomed. Pharmacother. | pmid:6819869 |
| Piotrowska H and Jagodzinski PP | Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. | 2007 | Biomed. Pharmacother. | pmid:17498915 |
| Mathew OP et al. | Butyrate, an HDAC inhibitor, stimulates interplay between different posttranslational modifications of histone H3 and differently alters G1-specific cell cycle proteins in vascular smooth muscle cells. | 2010 | Biomed. Pharmacother. | pmid:20970954 |
| Rawłuszko-Wieczorek AA et al. | Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer. | 2015 | Biomed. Pharmacother. | pmid:26349991 |
| Rawłuszko AA et al. | Reduced expression of steroid sulfatase in primary colorectal cancer. | 2013 | Biomed. Pharmacother. | pmid:23916543 |
| Rawłuszko AA et al. | Effect of butyrate on aromatase cytochrome P450 levels in HT29, DLD-1 and LoVo colon cancer cells. | 2012 | Biomed. Pharmacother. | pmid:22386365 |
| Raymond J and Chany C | Effects of arginine butyrate on bacterial growth. | 1986 | Biomed. Pharmacother. | pmid:3828482 |
| Xu CJ et al. | Immunoregulatory effects of ethyl-acetate fraction of extracts from Tetrastigma hemsleyanum Diels et. Gilg on immune functions of ICR mice. | 2008 | Biomed. Environ. Sci. | pmid:18837297 |
| Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
| Gupta KP and Mehrotra NK | Differential effects of butyric acid on mouse skin tumorigenesis. | 1997 | Biomed. Environ. Sci. | pmid:9448925 |
| Zhao G et al. | Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography. | 2006 | Biomed. Chromatogr. | pmid:16206138 |
| Park JH et al. | Rapid quantification of levosulpiride in human plasma using RP-HPLC-MS/MS for pharmacokinetic and bioequivalence study. | 2009 | Biomed. Chromatogr. | pmid:19488984 |
| Fuchs O et al. | Effect of hemin on poly (A)-containing RNA synthesis and transport from nucleus into cytoplasm in Friend cells of the Fw line. | 1984 | Biomed. Biochim. Acta | pmid:6593067 |
| Sun J et al. | Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. | 2015 | Biomed Res Int | pmid:26064905 |
| Skender B et al. | Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: a review. | 2012 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:23069883 |
| Vrba J et al. | HDAC inhibitors sodium butyrate and sodium valproate do not affect human ncor1 and ncor2 gene expression in HL-60 cells. | 2011 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:22286811 |
| Candan G et al. | Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery. | 2012 | Biomaterials | pmid:22743600 |
| Justin G and Guiseppi-Elie A | Characterization of electroconductive blends of poly(HEMA-co-PEGMA-co-HMMA-co-SPMA) and poly(Py-co-PyBA). | 2009 | Biomacromolecules | pmid:19705837 |
| Asran ASh et al. | Nanofibers from blends of polyvinyl alcohol and polyhydroxy butyrate as potential scaffold material for tissue engineering of skin. | 2010 | Biomacromolecules | pmid:21090703 |
| Kusumi R et al. | Cellulose ester-graft-poly(epsilon-caprolactone): effects of copolymer composition and intercomponent miscibility on the enzymatic hydrolysis behavior. | 2009 | Biomacromolecules | pmid:19655716 |
| Hornig S and Heinze T | Efficient approach to design stable water-dispersible nanoparticles of hydrophobic cellulose esters. | 2008 | Biomacromolecules | pmid:18393524 |
| Gomes FM et al. | Immobilization of lipase on chitin and its use in nonconventional biocatalysis. | 2004 Jan-Feb | Biomacromolecules | pmid:14715003 |
| Duvic M and Vu J | Update on the treatment of cutaneous T-cell lymphoma (CTCL): Focus on vorinostat. | 2007 | Biologics | pmid:19707308 |
| Prakash S et al. | Gut microbiota: next frontier in understanding human health and development of biotherapeutics. | 2011 | Biologics | pmid:21847343 |
| Kaminetzky D and Hymes KB | Denileukin diftitox for the treatment of cutaneous T-cell lymphoma. | 2008 | Biologics | pmid:19707452 |
| Ricco R and Kanduc D | Hepatitis B virus and Homo sapiens proteome-wide analysis: A profusion of viral peptide overlaps in neuron-specific human proteins. | 2010 | Biologics | pmid:20531967 |
| Moulding D et al. | Regulation of neutrophil apoptosis by sodium butyrate. | 1996 | Biologicals | pmid:9088543 |
| Khanavi M et al. | Cytotoxic activity of some marine brown algae against cancer cell lines. | 2010 | Biol. Res. | pmid:21157630 |
| Lee VH et al. | In vitro transformation of rabbit cytotrophoblast cells into syncytiotrophoblast: stimulation of hormone secretion by progesterone and dibutyryl cyclic 3',5'-adenosine monophosphate. | 1995 | Biol. Reprod. | pmid:7780009 |
| Vijayaraghavan S et al. | Calcium uptake by bovine epididymal spermatozoa is regulated by the redox state of the mitochondrial pyridine nucleotides. | 1989 | Biol. Reprod. | pmid:2752074 |
| Shi W et al. | Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. | 2003 | Biol. Reprod. | pmid:12646489 |
| Stafford JM et al. | Increasing histone acetylation in the hippocampus-infralimbic network enhances fear extinction. | 2012 | Biol. Psychiatry | pmid:22290116 |
| Schroeder FA et al. | Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. | 2007 | Biol. Psychiatry | pmid:16945350 |
| Matsumoto T et al. | Butyrate induces necrotic cell death in murine colonic epithelial cell MCE301. | 2006 | Biol. Pharm. Bull. | pmid:17015948 |
| Kang HW et al. | Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis. | 2002 | Biol. Pharm. Bull. | pmid:11824536 |
| Lee JY et al. | Effects of hydroxy pentacyclic triterpene acids from Forsythia viridissima on asthmatic responses to ovalbumin challenge in conscious guinea pigs. | 2010 | Biol. Pharm. Bull. | pmid:20118545 |
| Ha JH et al. | Modulation of radioligand binding to the GABA(A)-benzodiazepine receptor complex by a new component from Cyperus rotundus. | 2002 | Biol. Pharm. Bull. | pmid:11824542 |
| Muto N et al. | Hinokitiol induces differentiation of teratocarcinoma F9 cells. | 1995 | Biol. Pharm. Bull. | pmid:8593483 |
| Um SJ et al. | Potent cytotoxic effects of novel retinamide derivatives in ovarian cancer cells. | 2003 | Biol. Pharm. Bull. | pmid:14519946 |
| Oliveira de Melo J et al. | Anti-inflammatory activity of crude extract and fractions of Nectandra falcifolia leaves. | 2006 | Biol. Pharm. Bull. | pmid:17077521 |
| Luize PS et al. | Activity of neolignans isolated from Piper regnellii (MIQ.) C. DC. var. pallescens (C. DC.) YUNCK against Trypanosoma cruzi. | 2006 | Biol. Pharm. Bull. | pmid:17015964 |