| MeSH term | MeSH ID | Detail |
|---|---|---|
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Diabetic Ketoacidosis | D016883 | 16 associated lipids |
| Lymphoma, AIDS-Related | D016483 | 2 associated lipids |
| Milk Hypersensitivity | D016269 | 4 associated lipids |
| Pleural Effusion, Malignant | D016066 | 6 associated lipids |
| HIV Infections | D015658 | 20 associated lipids |
| Leukemia, Myeloid, Acute | D015470 | 19 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Gastrinoma | D015408 | 1 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pinto JT et al. | Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds. | 2011 | Amino Acids | pmid:20383543 |
| Andrews FM et al. | In vitro effects of hydrochloric acid and various concentrations of acetic, propionic, butyric, or valeric acids on bioelectric properties of equine gastric squamous mucosa. | 2006 | Am. J. Vet. Res. | pmid:17078749 |
| Minder HP et al. | In vitro fermentation of feces from normal and chronically diarrheal horses. | 1980 | Am. J. Vet. Res. | pmid:6447466 |
| Allemann M et al. | Effect of sodium butyric acid, sodium valerianic acid, and osmolarity on contractility of specimens of intestinal wall obtained from the cecum and spiral colon of healthy cows. | 2000 | Am. J. Vet. Res. | pmid:10850845 |
| Targowski SP and Klucinski W | Reduction in mitogenic response of bovine lymphocytes by ketone bodies. | 1983 | Am. J. Vet. Res. | pmid:6603180 |
| Mills SW et al. | Evaluation of the effects of short-chain fatty acids and extracellular pH on bovine neutrophil function in vitro. | 2006 | Am. J. Vet. Res. | pmid:17078753 |
| Cao XX et al. | Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. | 2001 | Am. J. Respir. Cell Mol. Biol. | pmid:11713097 |
| Gill RK and Dudeja PK | A novel facet to consider for the effects of butyrate on its target cells. Focus on "The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein". | 2011 | Am. J. Physiol., Cell Physiol. | pmid:21832244 |
| Gonçalves P et al. | The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein. | 2011 | Am. J. Physiol., Cell Physiol. | pmid:21775706 |
| Lam P et al. | Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17855769 |
| Loffing-Cueni D et al. | Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11698247 |
| Nakhoul NL et al. | pH sensitivity of ammonium transport by Rhbg. | 2010 | Am. J. Physiol., Cell Physiol. | pmid:20810915 |
| Cooper GJ and Fong P | Relationship between intracellular pH and chloride in Xenopus oocytes expressing the chloride channel ClC-0. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12388074 |
| Said HM et al. | Mechanism of nicotinic acid transport in human liver cells: experiments with HepG2 cells and primary hepatocytes. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17928533 |
| Kiela PR et al. | Molecular mechanism of rat NHE3 gene promoter regulation by sodium butyrate. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17344314 |
| Krishnan S et al. | Apical NHE isoforms differentially regulate butyrate-stimulated Na absorption in rat distal colon. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12878493 |
| Resta-Lenert S et al. | Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11698242 |
| Zhao L et al. | ¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. | 2011 | Am. J. Physiol. Renal Physiol. | pmid:21228107 |
| Nakhoul NL et al. | Ammonium interaction with the epithelial sodium channel. | 2001 | Am. J. Physiol. Renal Physiol. | pmid:11502598 |
| Laughery MD et al. | Selective basolateral localization of overexpressed Na-K-ATPase beta1- and beta2- subunits is disrupted by butryate treatment of MDCK cells. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17344187 |
| Kumar P et al. | Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. | 2017 | Am. J. Physiol. Renal Physiol. | pmid:28566502 |
| Brown AC et al. | RhCG is the major putative ammonia transporter expressed in the human kidney, and RhBG is not expressed at detectable levels. | 2009 | Am. J. Physiol. Renal Physiol. | pmid:19357182 |
| Leipziger J et al. | PKA site mutations of ROMK2 channels shift the pH dependence to more alkaline values. | 2000 | Am. J. Physiol. Renal Physiol. | pmid:11053053 |
| Park GY et al. | Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. | 2004 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:14672923 |
| Bao JX et al. | Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20061541 |
| Ochiai K et al. | Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557577 |
| Rexhaj E et al. | Fetal programming of pulmonary vascular dysfunction in mice: role of epigenetic mechanisms. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21536851 |
| Arvans DL et al. | Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15528251 |
| Musch MW et al. | SCFA increase intestinal Na absorption by induction of NHE3 in rat colon and human intestinal C2/bbe cells. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11254495 |
| Zimmerman MA et al. | Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22517765 |
| Shie JL et al. | Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11005769 |
| Lal S et al. | Vagal afferent responses to fatty acids of different chain length in the rat. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11557510 |
| Ogawa H et al. | Regulated production of the chemokine CCL28 in human colon epithelium. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15246961 |
| Alrefai WA et al. | Molecular cloning and promoter analysis of downregulated in adenoma (DRA). | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17761837 |
| Saksena S et al. | PKC-dependent stimulation of the human MCT1 promoter involves transcription factor AP2. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19033536 |
| Kumar A et al. | Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26272259 |
| Marcil V et al. | Modulation of lipid synthesis, apolipoprotein biogenesis, and lipoprotein assembly by butyrate. | 2002 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12121881 |
| Schweigel M et al. | Mechanisms of Mg(2+) transport in cultured ruminal epithelial cells. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:10712259 |
| Borthakur A et al. | The probiotic Lactobacillus plantarum counteracts TNF-{alpha}-induced downregulation of SMCT1 expression and function. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20671196 |
| Cuche G et al. | Desensitization of ileal vagal receptors by short-chain fatty acids in pigs. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11292611 |
| Kolar SS et al. | Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17717041 |
| Alrefai WA et al. | Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:14525727 |
| Perry MD and Sandle GI | Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19407217 |
| Gaudier E et al. | Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15308471 |
| Wu JT et al. | Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11171632 |
| Vidyasagar S et al. | Role of short-chain fatty acids in colonic HCO(3) secretion. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15677553 |
| Pawelka AJ and Huizinga JD | Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25540235 |
| Hadjiagapiou C et al. | Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate transporter 1 promoter. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15691871 |
| Yuan L et al. | Schlafen 3 induction by cyclic strain regulates intestinal epithelial differentiation. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20299602 |
| Pender SL et al. | Butyrate upregulates stromelysin-1 production by intestinal mesenchymal cells. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11052988 |