butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Maruo T et al. | Discordant induction of tumor-associated antigen, TA-4 and chorionic gonadotropin beta in cultured cervical carcinoma cells. | 1987 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:3493311 |
Moebius U et al. | Butyrate-synchronized cloned T cells retain their dependence on interleukin-2 for growth induction. A model system for growth regulation. | 1987 | Exp. Cell Res. | pmid:3493914 |
Nishimura T et al. | The role of lymphokine-activated cell-associated antigen. II. Distribution and correlation with cell cycle. | 1987 | Cell. Immunol. | pmid:3495348 |
Jackson JA et al. | Physiological responses in rats fed extracts of endophyte infected tall fescue seed. | 1987 | Drug Chem Toxicol | pmid:3428190 |
Riley TV | A note on hydrolysis of tributyrin by Branhamella and Neisseria. | 1987 | J. Appl. Bacteriol. | pmid:3624107 |
Pandey RS and Kanungo MS | Conformation of chromatin of the skeletal muscle of developing rats and its modulation by sodium butyrate. | 1987 | Indian J. Biochem. Biophys. | pmid:3428915 |
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Sakata T | Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors. | 1987 | Br. J. Nutr. | pmid:3620440 |
Rowe M et al. | Monoclonal antibodies to the latent membrane protein of Epstein-Barr virus reveal heterogeneity of the protein and inducible expression in virus-transformed cells. | 1987 | J. Gen. Virol. | pmid:2438376 |
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Zucker RM et al. | Differential hemoglobin synthesis in murine erythroleukemic cells: hemin effects. | 1987 | Cell Biochem. Funct. | pmid:3469035 |
Alitalo R et al. | Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines. | 1987 | EMBO J. | pmid:3475202 |
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Rouault TA et al. | Influence of altered transcription on the translational control of human ferritin expression. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3476949 |
Alitalo R | The bcr-c-abl tyrosine kinase activity is extinguished by TPA in K562 leukemia cells. | 1987 | FEBS Lett. | pmid:3477472 |
Hong SJ and Ko LW | Activation of protein expression in clonal glioma cells by sodium butyrate. | 1987 | Gaoxiong Yi Xue Ke Xue Za Zhi | pmid:3482265 |
Davidson AM and Halestrap AP | Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content. | 1987 | Biochem. J. | pmid:2825649 |
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Kooistra T et al. | Butyrate stimulates tissue-type plasminogen-activator synthesis in cultured human endothelial cells. | 1987 | Biochem. J. | pmid:2827633 |
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Papoutsakis ET et al. | Transport of substrates and metabolites and their effect on cell metabolism (in butyric-acid and methylotrophic fermentations). | 1987 | Ann. N. Y. Acad. Sci. | pmid:2829684 |
Cohn PD et al. | Differences in nonspecific esterase from normal and leukemic monocytes. | 1987 | Blood | pmid:3580567 |
Gupta KP and Mehrotra NK | Effect of butyric acid on 12-O-tetradecanoylphorbol-13-acetate-(TPA) induced mouse skin ornithine decarboxylase (ODC). | 1987 | Carcinogenesis | pmid:3664957 |
Paul CY et al. | Comparison of the pharmacokinetics of AMSA and AMSA-lactate in patients with acute nonlymphoblastic leukemia. | 1987 | Ther Drug Monit | pmid:3672568 |
Fiehn NE | Biochemical characterization of nine oral small-sized spirochete strains containing one endoflagellum from each cell-end. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:3673586 |
Kristev A et al. | The impact of butyric acid on the cardiovascular system. | 1987 | Cor Vasa | pmid:3677720 |
Miller AA et al. | Clinical pharmacology of sodium butyrate in patients with acute leukemia. | 1987 | Eur J Cancer Clin Oncol | pmid:3678322 |
Naguib FN et al. | Effects of N,N-dimethylformamide and sodium butyrate on enzymes of pyrimidine metabolism in cultured human tumor cells. | 1987 | Leuk. Res. | pmid:3682865 |
Merle-Beral H et al. | A T chronic lymphocytic leukemia with large granular lymphocytes. Phenotype and functions of leukemic cells under in vitro treatment by differentiation inducers. | 1987 | Cancer | pmid:3545432 |
Nakanishi T and Hashimoto K | The differential reactivity of benign and malignant nevomelanocytic lesions with mouse monoclonal antibody TNKH1. | 1987 | Cancer | pmid:3545436 |
Clarke DO and Brown NA | Valproic acid teratogenesis and embryonic lipid metabolism. | 1987 | Arch. Toxicol. Suppl. | pmid:3115231 |
Kakizoe H and Ninagawa T | [The development of enzyme immunoassay for prostaglandin F2 alpha]. | 1987 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:3546538 |
Nishigori C and Takebe H | Sodium butyrate stimulates cellular recovery from UV damage in xeroderma pigmentosum cells belonging to complementation group F. | 1987 | Jpn. J. Cancer Res. | pmid:3117749 |
Nelson NF et al. | Modulation of secreted plasminogen activator activity of human renal carcinoma cells by dimethylsulfoxide, butyrate and retinoate. | 1987 | Cancer Lett. | pmid:3548947 |
Philippe J et al. | Transcriptional regulation of genes encoding insulin, glucagon, and angiotensinogen by sodium butyrate in a rat islet cell line. | 1987 | Mol. Cell. Biol. | pmid:3550424 |
Katoh K and Tsuda T | Effects of intravenous injection of butyrate on the exocrine pancreatic secretion in guinea pigs. | 1987 | Comp Biochem Physiol A Comp Physiol | pmid:2441923 |
Ortiz-Caro J et al. | Down-regulation of thyroid hormone nuclear receptor levels by L-triiodothyronine in cultured glial C6 cells. | 1987 | Mol. Cell. Endocrinol. | pmid:3556756 |
Lloyd CJ et al. | Angiotensin converting enzyme induction by cyclic AMP and analogues in cultured endothelial cells. | 1987 | Mol. Cell. Endocrinol. | pmid:2443404 |
Mitsuhashi T et al. | n-Butyrate increases the level of thyroid hormone nuclear receptor in non-pituitary cultured cells. | 1987 | J. Biol. Chem. | pmid:3558403 |
Milsted A et al. | Phenotypes of HeLa S3 variant cell lines resistant to growth inhibition by sodium butyrate. | 1987 | In Vitro Cell. Dev. Biol. | pmid:2439485 |
Monahan-Earley RA et al. | Nonspecific esterase activity expressed in Weibel-Palade bodies of cloned guinea pig aortic endothelial cells. | 1987 | J. Histochem. Cytochem. | pmid:3559181 |
Andrey D | A simple gas chromatography method for the determination of ethylcarbamate in spirits. | 1987 | Z Lebensm Unters Forsch | pmid:3617935 |
Hartmanis MG | Butyrate kinase from Clostridium acetobutylicum. | 1987 | J. Biol. Chem. | pmid:3027059 |
Dobson DE et al. | Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation. | 1987 | J. Biol. Chem. | pmid:3027100 |
Gudas JM and Hankinson O | Regulation of cytochrome P-450c in differentiated and dedifferentiated rat hepatoma cells: role of the Ah receptor. | 1987 | Somat. Cell Mol. Genet. | pmid:2821631 |
Nègre A et al. | Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. | 1987 | Biochim. Biophys. Acta | pmid:3030438 |
Quarless SA and Heinrich G | Regulation of nerve growth factor gene expression in primary brain monolayer cultures: effects of dibutyryl cyclic AMP and sodium butyrate. | 1987 | Brain Res. | pmid:2823959 |
Grippo JF and Gudas LJ | The effect of dibutyryl cyclic AMP and butyrate on F9 teratocarcinoma cellular retinoic acid-binding protein activity. | 1987 | J. Biol. Chem. | pmid:3031026 |
Wiegandt H et al. | Retinoic acid alters the metabolic 3H-labelling of glycosphingolipids. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3032172 |
Van Dyck E and Piot P | Enzyme profile of Haemophilus ducreyi strains isolated on different continents. | 1987 | Eur. J. Clin. Microbiol. | pmid:3032608 |
Anisimová E et al. | Chemically purified serum factor can induce both Epstein-Barr virus antigen synthesis and cell differentiation. | 1987 | Arch. Virol. | pmid:3034214 |
Su WJ et al. | Role of volatile fatty acids in colonization resistance to Clostridium difficile in gnotobiotic mice. | 1987 | Infect. Immun. | pmid:3596806 |
Kameyama T et al. | [Behavioral pharmacological action of Ca-4-(3,5-dihydroxy-3-methylpenthylamido) butyrate (mevalonic GABA, MV-GABA)]. | 1987 | Nippon Yakurigaku Zasshi | pmid:3034749 |
Ceccarelli P et al. | Resistance to thyroid hormone diagnosed by the reduced response of fibroblasts to the triiodothyronine-induced suppression of fibronectin synthesis. | 1987 | J. Clin. Endocrinol. Metab. | pmid:3597704 |
Otani S et al. | Biphasic effects of dibutyryl cyclic adenosine 3',5'-monophosphate on synergistic stimulation of DNA synthesis by diacylglycerol, and the ionophore A23187 in guinea pig lymphocytes. | 1987 | Life Sci. | pmid:3035313 |
Oya Y et al. | The biological activity of hydrogen peroxide. III. Induction of Epstein-Barr virus via indirect action, as compared with TPA and teleocidin. | 1987 | Int. J. Cancer | pmid:3036721 |
Andrews GK and Adamson ED | Butyrate selectively activates the metallothionein gene in teratocarcinoma cells and induces hypersensitivity to metal induction. | 1987 | Nucleic Acids Res. | pmid:3601676 |
Boos H et al. | Enhancement of Epstein-Barr virus membrane protein (LMP) expression by serum, TPA, or n-butyrate in latently infected Raji cells. | 1987 | Virology | pmid:3037776 |
Chou JY and Takahashi S | Control of placental alkaline phosphatase gene expression in HeLa cells: induction of synthesis by prednisolone and sodium butyrate. | 1987 | Biochemistry | pmid:3651399 |
Nutter LM et al. | Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells. | 1987 | Cancer Res. | pmid:3038311 |
Byrd JC et al. | Proenkephalin gene expression in the PC12 pheochromocytoma cell line: stimulation by sodium butyrate. | 1987 | Endocrinology | pmid:3653029 |
Menon R et al. | Metabolism of 7,12-dimethylbenz[a]anthracene by mouse mammary cells in serum-free organ culture medium. | 1987 | Eur J Cancer Clin Oncol | pmid:3038562 |
Lampugnani MG et al. | Effects of dimethyl sulfoxide (DMSO) on microfilament organization, cellular adhesion, and growth of cultured mouse B16 melanoma cells. | 1987 | Exp. Cell Res. | pmid:3653263 |
Horning MG et al. | Analytical methods for the study of urinary thioether metabolites in the rat and guinea pig. | 1987 | J. Chromatogr. | pmid:3654858 |
Festing MF and Eydmann T | Genetic variation in the response of mice to xenobiotics in vitro. I. General methodology and response to some model compounds. | 1987 | Toxicol In Vitro | pmid:20647076 |
Scheppach WM et al. | Fecal short-chain fatty acid (SCFA) analysis by capillary gas-liquid chromatography. | 1987 | Am. J. Clin. Nutr. | pmid:3661480 |
Hansen HO and Knudsen J | Effect of exogenous long-chain fatty acids on individual fatty acid synthesis by dispersed ruminant mammary gland cells. | 1987 | J. Dairy Sci. | pmid:3624591 |
Ryan MP et al. | Butyrate-induced cytoarchitectural reorganization of Mallory body-containing rat hepatic tumor cells. | 1987 | J. Natl. Cancer Inst. | pmid:3041093 |
Garr-Peters JM and Ho CS | Oxygen transfer in the corneal-contact lens system. | 1987 | Crit Rev Biomed Eng | pmid:3319414 |
de Vasconcelos PR et al. | Time course of changes in hepatic metabolism in response to sepsis in the rat: impairment of gluconeogenesis and ketogenesis in vitro. | 1987 | Clin. Sci. | pmid:3297469 |
Vu QA et al. | Polyamines inhibit the yeast histone deacetylase. | 1987 | FEBS Lett. | pmid:3301411 |
Bourne GA and Baldwin DM | Evidence for cAMP as a mediator of gonadotropin secretion from female pituitaries. | 1987 | Am. J. Physiol. | pmid:2820237 |
Furukawa M and Umeda R | Inhibitory effect of retinoid (E5166) on cell growth and suppressive effect on Epstein-Barr virus early-antigen induction by n-butyrate in nasopharyngeal hybrid cells. | 1987 | Auris Nasus Larynx | pmid:2820366 |
Sheffield LG | Cyclic cytidine monophosphate stimulates DNA synthesis by bovine mammary tissue in vitro. | 1987 | Cell Biol. Int. Rep. | pmid:2820591 |
Yen A et al. | Control of HL-60 monocytic differentiation. Different pathways and uncoupled expression of differentiation markers. | 1987 | Exp. Cell Res. | pmid:3023118 |
Polack A et al. | Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells. | 1987 | EMBO J. | pmid:3691477 |
Nakagawa Y and Perentes E | Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid. | 1987 | Ophthalmic Res. | pmid:3696696 |
Gum JR et al. | Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase. | 1987 | J. Biol. Chem. | pmid:3805014 |
Peleran JC et al. | Identification of the cooked food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and its N-acetylated and 3-N-demethylated metabolites in rat urine. | 1987 | Toxicology | pmid:3810661 |
Byrd JC and Alho H | Differentiation of PC12 pheochromocytoma cells by sodium butyrate. | 1987 | Brain Res. | pmid:3815113 |
Gout PW | Transient requirement for prolactin as a growth initiator following treatment of autonomous Nb2 node rat lymphoma cell cultures with butyrate. | 1987 | Cancer Res. | pmid:3815371 |
Augenlicht LH et al. | Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro. | 1987 | Cancer Res. | pmid:3664505 |
Engelmann GL et al. | Effect of sodium butyrate on primary cultures of adult rat hepatocytes. | 1987 | In Vitro Cell. Dev. Biol. | pmid:2880833 |
Lee KN et al. | Induction of cellular transglutaminase biosynthesis by sodium butyrate. | 1987 | Biochim. Biophys. Acta | pmid:2881581 |
Vernay M | Effects of plasma aldosterone on butyrate absorption and metabolism in the rabbit proximal colon. | 1987 | Comp Biochem Physiol A Comp Physiol | pmid:2882896 |
Nordenberg J et al. | Biochemical and ultrastructural alterations accompany the anti-proliferative effect of butyrate on melanoma cells. | 1987 | Br. J. Cancer | pmid:2886147 |
Woodall PF and Mackie RI | Caecal size and function in the rock elephant shrew Elephantulus myurus (Insectivora, Macroscelididae) and the Namaqua rock mouse Aethomys namaquensis (Rodentia, Muridae). | 1987 | Comp Biochem Physiol A Comp Physiol | pmid:2886272 |
Zhu XZ and Chuang DM | Comparison of the butyrate effects on neurotransmitter receptors in neurohybrids NG108-15 and NCB-20 cells. | 1987 | Life Sci. | pmid:2886888 |
Byrd JC and Lichti U | Two types of transglutaminase in the PC12 pheochromocytoma cell line. Stimulation by sodium butyrate. | 1987 | J. Biol. Chem. | pmid:2887561 |
Smith TJ | n-Butyrate inhibition of hyaluronate synthesis in cultured human fibroblasts. | 1987 | J. Clin. Invest. | pmid:3106417 |
Malik H et al. | Chemical inducers of differentiation, dimethylsulfoxide, butyric acid, and dimethylthiourea, induce selective ultrastructural patterns in B16 melanoma cells. | 1987 | Biol. Cell | pmid:2960403 |
Lea MA | Relationship of H1(0) histone to differentiation and cancer. | 1987 | Cancer Biochem. Biophys. | pmid:3325165 |