butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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Hidaka M et al. | Three lysophosphatidic acids with a distinct long chain moiety differently affect cell differentiation of human colon epithelial cells to goblet cells. | 2018 | Life Sci. | pmid:29412173 |
da Silva JS et al. | Nutritive value and fermentation quality of palisadegrass and stylo mixed silages. | 2018 | Anim. Sci. J. | pmid:28905506 |
Johnson J et al. | Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice. | 2018 | Neurotoxicology | pmid:28610743 |
Sun H et al. | Effects of addition of Aspergillus oryzae culture and 2-hydroxyl-4-(methylthio) butanoic acid on milk performance and rumen fermentation of dairy cows. | 2017 | Anim. Sci. J. | pmid:27506446 |
Wang Y et al. | A Co-Drug of Butyric Acid Derived from Fermentation Metabolites of the Human Skin Microbiome Stimulates Adipogenic Differentiation of Adipose-Derived Stem Cells: Implications in Tissue Augmentation. | 2017 | J. Invest. Dermatol. | pmid:27498050 |
Zhang Q et al. | Histone acetylation and reactive oxygen species are involved in the preprophase arrest induced by sodium butyrate in maize roots. | 2017 | Protoplasma | pmid:26781092 |
Gulfam A et al. | Characteristics of lactic acid bacteria isolates and their effect on the fermentation quality of Napier grass silage at three high temperatures. | 2017 | J. Sci. Food Agric. | pmid:27539868 |
Machado CF et al. | Conditional Deletion of in Olfactory Sensory Neurons Leads to Olfactory Impairment. | 2017 | J. Neurosci. | pmid:29118104 |
Kobayashi H et al. | Clostridium pabulibutyricum sp. nov., a butyric-acid-producing organism isolated from high-moisture grass silage. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:29034861 |
Du H et al. | Exploring the microbial origins of p-cresol and its co-occurrence pattern in the Chinese liquor-making process. | 2017 | Int. J. Food Microbiol. | pmid:28843121 |
Owusu BY and Klampfer L | Modulation of STAT1-Driven Transcriptional Activity by Histone Deacetylases. | 2017 | Methods Mol. Biol. | pmid:27761828 |
Andersen AD et al. | Supplementation with Lactobacillus paracasei or Pediococcus pentosaceus does not prevent diarrhoea in neonatal pigs infected with Escherichia coli F18. | 2017 | Br. J. Nutr. | pmid:28720151 |
Hrgovic I et al. | Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR-2 protein half-life in part via a VE-cadherin-dependent mechanism. | 2017 | Exp. Dermatol. | pmid:27487811 |
Yokoyama Y et al. | Profile of preoperative fecal organic acids closely predicts the incidence of postoperative infectious complications after major hepatectomy with extrahepatic bile duct resection: Importance of fecal acetic acid plus butyric acid minus lactic acid gap. | 2017 | Surgery | pmid:28684159 |
Hofmanová J et al. | Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities. | 2017 | Eur J Nutr | pmid:26983609 |
Anantharaju PG et al. | Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC). | 2017 | PLoS ONE | pmid:29190639 |
Seifrtová M et al. | Haemanthamine alters sodium butyrate-induced histone acetylation, p21 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells. | 2017 | Phytomedicine | pmid:28991639 |
Sałkowska A et al. | Differentiation stage-specific effect of histone deacetylase inhibitors on the expression of RORγT in human lymphocytes. | 2017 | J. Leukoc. Biol. | pmid:28951421 |
Wu Q et al. | Tailoring the Oxidative Stress Tolerance of Clostridium tyrobutyricum CCTCC W428 by Introducing Trehalose Biosynthetic Capability. | 2017 | J. Agric. Food Chem. | pmid:28925260 |
Sanz M et al. | Namalides B and C and Spumigins K-N from the Cultured Freshwater Cyanobacterium Sphaerospermopsis torques-reginae. | 2017 | J. Nat. Prod. | pmid:28876933 |
Górka P et al. | Effect of butyrate infusion into the rumen on butyrate flow to the duodenum, selected gene expression in the duodenum epithelium, and nutrient digestion in sheep. | 2017 | J. Anim. Sci. | pmid:28726987 |
Chang PJ et al. | Effects of the NEDD8-Activating Enzyme Inhibitor MLN4924 on Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. | 2017 | J. Virol. | pmid:28701396 |
Ito T et al. | Occurrence of the (2R,3S)-Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus. | 2017 | J. Agric. Food Chem. | pmid:28686838 |
Chen X et al. | Sodium butyrate regulates Th17/Treg cell balance to ameliorate uveitis via the Nrf2/HO-1 pathway. | 2017 | Biochem. Pharmacol. | pmid:28684304 |
Yan H and Ajuwon KM | Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. | 2017 | PLoS ONE | pmid:28654658 |
Meenongyai W et al. | Effects of forage ensiling and ration fermentation on total mixed ration pH, ruminal fermentation and performance of growing Holstein-Zebu cross steers. | 2017 | Anim. Sci. J. | pmid:28370998 |
Zheng ML et al. | Dynamics of microbial community during ensiling direct-cut alfalfa with and without LAB inoculant and sugar. | 2017 | J. Appl. Microbiol. | pmid:28370869 |
Foote AP et al. | Effect of abomasal butyrate infusion on gene expression in the duodenum of lambs. | 2017 | J. Anim. Sci. | pmid:28380531 |
Paiva I et al. | Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage. | 2017 | Hum. Mol. Genet. | pmid:28369321 |
Lynch H et al. | Investigation of in-feed organic acids as a low cost strategy to combat Salmonella in grower pigs. | 2017 | Prev. Vet. Med. | pmid:28364832 |
Fu H et al. | Butyric acid production from lignocellulosic biomass hydrolysates by engineered Clostridium tyrobutyricum overexpressing xylose catabolism genes for glucose and xylose co-utilization. | 2017 | Bioresour. Technol. | pmid:28343058 |
Kim YH and Lee JK | Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression. | 2017 | Cell. Immunol. | pmid:28341057 |
Egawa G et al. | SCFAs Control Skin Immune Responses via Increasing Tregs. | 2017 | J. Invest. Dermatol. | pmid:28340682 |
Olsen S | Effects of ultra-high dilutions of sodium butyrate on viability and gene expression in HEK 293 cells. | 2017 | Homeopathy | pmid:28325222 |
Zhang J et al. | Metabolic engineering of Clostridium tyrobutyricum for n-butanol production from sugarcane juice. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28238080 |
Mathew MP et al. | Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid. | 2017 | Chembiochem | pmid:28218815 |
Maeshige N et al. | Low-Intensity Ultrasound Enhances Histone Acetylation and Inhibition of Interleukin 6 Messenger RNA Expression by the Histone Deacetylase Inhibitor Sodium Butyrate in Fibroblasts. | 2017 | J Ultrasound Med | pmid:28195362 |
Yoo M et al. | Metabolic flexibility of a butyrate pathway mutant of Clostridium acetobutylicum. | 2017 | Metab. Eng. | pmid:28159643 |
Nakazawa A et al. | Evaluation of Adsorption Characteristics of a Fibrous Adsorbent Containing Zwitter-Ionic Functional Group, Targeting Organic Acids. | 2017 | J. UOEH | pmid:28331124 |
Millat T and Winzer K | Mathematical modelling of clostridial acetone-butanol-ethanol fermentation. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28210797 |
Johnstone M et al. | Characterization of the Pro-Inflammatory Cytokine IL-1β on Butyrate Oxidation in Colorectal Cancer Cells. | 2017 | J. Cell. Biochem. | pmid:27922186 |
Shirasugi M et al. | Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27914813 |
Yan JK et al. | Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27888107 |
Schwarz A et al. | The Short-Chain Fatty Acid Sodium Butyrate Functions as a Regulator of the Skin Immune System. | 2017 | J. Invest. Dermatol. | pmid:27887954 |
Ra CH et al. | Hyper-thermal acid hydrolysis and adsorption treatment of red seaweed, Gelidium amansii for butyric acid production with pH control. | 2017 | Bioprocess Biosyst Eng | pmid:27878375 |
Herrick KJ et al. | Single-dose infusion of sodium butyrate, but not lactose, increases plasma β-hydroxybutyrate and insulin in lactating dairy cows. | 2017 | J. Dairy Sci. | pmid:27837980 |
Zhang C et al. | Differential effect of early antibiotic intervention on bacterial fermentation patterns and mucosal gene expression in the colon of pigs under diets with different protein levels. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27913852 |
Meneses-Reyes JC et al. | Biochemical methane potential of oil-extracted microalgae and glycerol in co-digestion with chicken litter. | 2017 | Bioresour. Technol. | pmid:27864134 |
Zhang K et al. | Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. | 2017 | Appl. Biochem. Biotechnol. | pmid:27832512 |