butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Psychophysiologic Disorders D011602 3 associated lipids
Radiation Injuries D011832 14 associated lipids
Retinoblastoma D012175 12 associated lipids
Retroviridae Infections D012192 4 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Sarcoma 180 D012510 21 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Osteosarcoma D012516 50 associated lipids
Seizures D012640 87 associated lipids
Starvation D013217 47 associated lipids
Thalassemia D013789 8 associated lipids
Thrombosis D013927 49 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Uremia D014511 33 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Dementia, Vascular D015140 7 associated lipids
Gastrinoma D015408 1 associated lipids
Weight Gain D015430 101 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
HIV Infections D015658 20 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Strongylida Infections D017206 5 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Hepatoblastoma D018197 10 associated lipids
Teratocarcinoma D018243 7 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Multiple Chemical Sensitivity D018777 4 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Pouchitis D019449 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Genomic Instability D042822 7 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
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Clouet PM and Bourre JM Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. 1988 J. Neurochem. pmid:3361304
Salam S Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. 1988 Pak J Pharm Sci pmid:16414615
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Zhu XZ and Chuang DM Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. 1988 J. Neurochem. pmid:2826684
Rossi JF et al. Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. 1988 Cancer Res. pmid:2830017
Takeyasu K et al. Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. 1988 J. Biol. Chem. pmid:2831227
Sorimachi K Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. 1988 Cell Biochem. Funct. pmid:2832093
Sack TL et al. Cyclic-AMP-stimulated synthesis and release of carcinoembryonic antigen by pancreatic cancer cells. 1988 Int. J. Pancreatol. pmid:2834472
Pennypacker KR et al. Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines. 1988 J. Neurochem. pmid:2834519
Murray SA and Taylor F Dibutyryl cyclic AMP modulation of gap junctions in SW-13 human adrenal cortical tumor cells. 1988 Am. J. Anat. pmid:2835894
Spiegel S Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin. 1988 Biochim. Biophys. Acta pmid:2835987
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Nishimura J et al. Regulation of biosynthesis and phosphorylation of P210bcr/abl protein during differentiation induction of K 562 cells. 1988 Leuk. Res. pmid:2464113
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Boerner P and Saier MH Effects of 5-azacytidine, sodium butyrate, and phorbol esters on amino acid transport system A in a kidney epithelial cell line, MDCK: evidence for multiple mechanisms of regulation. 1988 J. Cell. Physiol. pmid:2459137
Burns LJ et al. Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. 1988 Blood pmid:2460154
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Asher C and Garty H Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3140240
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Fischkoff SA Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions. 1988 Leuk. Res. pmid:3184985
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Januszewicz E et al. Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. 1988 Med Oncol Tumor Pharmacother pmid:3193830
Rhoads DB et al. Evidence for expression of the facilitated glucose transporter in rat hepatocytes. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3194405
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Graham KA and Buick RN Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. 1988 J. Cell. Physiol. pmid:3294239
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Yeger H et al. Phenotypic and molecular characterization of inducible human neuroblastoma cell lines. 1988 Differentiation pmid:3243386
Chatham J et al. Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. 1988 FEBS Lett. pmid:3169268
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Gressner AM and Haarmann R Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). 1988 Biochem. Pharmacol. pmid:3178890
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Leith JT Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine. 1988 Int. J. Radiat. Oncol. Biol. Phys. pmid:3182335
Chang CC et al. Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. 1988 Zhonghua Yi Xue Za Zhi (Taipei) pmid:3066455
Campbell M and Chader GJ Retinoblastoma cells in tissue culture. 1988 Ophthalmic Paediatr Genet pmid:3068600
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Herold KM and Rothberg PG Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. 1988 Oncogene pmid:3078950
Hidal JT and Kaplan MM Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. 1988 Metab. Clin. Exp. pmid:2838733
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Davidson AM and Halestrap AP Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. 1988 Biochem. J. pmid:2845949
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Yokochi T et al. Effect of activation of the Epstein-Barr virus genome on expression of B cell differentiation antigens of Burkitt's lymphoma lines. 1988 Microbiol. Immunol. pmid:2850450
Morise T et al. Biological activity of partially purified digitalis-like substance and Na-K-ATPase inhibitor in rats. 1988 Jpn. Circ. J. pmid:2852264
Ortiz-Caro J et al. Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. 1988 Endocrinology pmid:2836168
Li JS and Cheng YC Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. 1988 Virus Genes pmid:2852412
Prasad S and Thakur MK Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. 1988 Biochem. Int. pmid:3365268
Niles RM et al. The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. 1988 Cancer Invest. pmid:3365571
Leith JT Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. 1988 J. Natl. Cancer Inst. pmid:3367384
Cattini PA et al. Effect of butyrate on thyroid hormone-mediated gene expression in rat pituitary tumour cells. 1988 Mol. Cell. Endocrinol. pmid:3371552
Leith JT et al. Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. 1988 Radiat. Res. pmid:3375444
Joshi SS et al. Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. 1988 Cancer Detect. Prev. pmid:3390859
Kamech N and Seif R Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. 1988 Exp. Cell Res. pmid:3391246
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Tatsuka M et al. An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. 1988 Exp. Cell Res. pmid:3409976
Drucker DJ et al. Proglucagon gene expression and posttranslational processing in a hamster islet cell line. 1988 Endocrinology pmid:3416818
Szabad J et al. The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. 1988 Mol. Gen. Genet. pmid:3422705
Giancotti V et al. Butyrate effect on nuclear proteins of two Chinese hamster cell lines. 1988 Exp. Cell Res. pmid:3335229
Spector R Fatty acid transport through the blood-brain barrier. 1988 J. Neurochem. pmid:3335863
Virtanen I et al. Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. 1988 Lab. Invest. pmid:3141718