butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Maruo T et al. | Discordant induction of tumor-associated antigen, TA-4 and chorionic gonadotropin beta in cultured cervical carcinoma cells. | 1987 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:3493311 |
Moebius U et al. | Butyrate-synchronized cloned T cells retain their dependence on interleukin-2 for growth induction. A model system for growth regulation. | 1987 | Exp. Cell Res. | pmid:3493914 |
Nishimura T et al. | The role of lymphokine-activated cell-associated antigen. II. Distribution and correlation with cell cycle. | 1987 | Cell. Immunol. | pmid:3495348 |
Jackson JA et al. | Physiological responses in rats fed extracts of endophyte infected tall fescue seed. | 1987 | Drug Chem Toxicol | pmid:3428190 |
Pandey RS and Kanungo MS | Conformation of chromatin of the skeletal muscle of developing rats and its modulation by sodium butyrate. | 1987 | Indian J. Biochem. Biophys. | pmid:3428915 |
el-Deriny SE et al. | Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells. | 1987 | Pancreas | pmid:3575313 |
Cohn PD et al. | Differences in nonspecific esterase from normal and leukemic monocytes. | 1987 | Blood | pmid:3580567 |
Gupta KP and Mehrotra NK | Effect of butyric acid on 12-O-tetradecanoylphorbol-13-acetate-(TPA) induced mouse skin ornithine decarboxylase (ODC). | 1987 | Carcinogenesis | pmid:3664957 |
Paul CY et al. | Comparison of the pharmacokinetics of AMSA and AMSA-lactate in patients with acute nonlymphoblastic leukemia. | 1987 | Ther Drug Monit | pmid:3672568 |
Fiehn NE | Biochemical characterization of nine oral small-sized spirochete strains containing one endoflagellum from each cell-end. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:3673586 |
Katoh K and Tsuda T | Effects of intravenous injection of butyrate on the exocrine pancreatic secretion in guinea pigs. | 1987 | Comp Biochem Physiol A Comp Physiol | pmid:2441923 |
Lloyd CJ et al. | Angiotensin converting enzyme induction by cyclic AMP and analogues in cultured endothelial cells. | 1987 | Mol. Cell. Endocrinol. | pmid:2443404 |
Hartmanis MG | Butyrate kinase from Clostridium acetobutylicum. | 1987 | J. Biol. Chem. | pmid:3027059 |
Dobson DE et al. | Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation. | 1987 | J. Biol. Chem. | pmid:3027100 |
Nègre A et al. | Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. | 1987 | Biochim. Biophys. Acta | pmid:3030438 |
Byrd JC et al. | Proenkephalin gene expression in the PC12 pheochromocytoma cell line: stimulation by sodium butyrate. | 1987 | Endocrinology | pmid:3653029 |
Lampugnani MG et al. | Effects of dimethyl sulfoxide (DMSO) on microfilament organization, cellular adhesion, and growth of cultured mouse B16 melanoma cells. | 1987 | Exp. Cell Res. | pmid:3653263 |
Horning MG et al. | Analytical methods for the study of urinary thioether metabolites in the rat and guinea pig. | 1987 | J. Chromatogr. | pmid:3654858 |
Scheppach WM et al. | Fecal short-chain fatty acid (SCFA) analysis by capillary gas-liquid chromatography. | 1987 | Am. J. Clin. Nutr. | pmid:3661480 |
Hansen HO and Knudsen J | Effect of exogenous long-chain fatty acids on individual fatty acid synthesis by dispersed ruminant mammary gland cells. | 1987 | J. Dairy Sci. | pmid:3624591 |
Bourne GA and Baldwin DM | Evidence for cAMP as a mediator of gonadotropin secretion from female pituitaries. | 1987 | Am. J. Physiol. | pmid:2820237 |
Furukawa M and Umeda R | Inhibitory effect of retinoid (E5166) on cell growth and suppressive effect on Epstein-Barr virus early-antigen induction by n-butyrate in nasopharyngeal hybrid cells. | 1987 | Auris Nasus Larynx | pmid:2820366 |
Sheffield LG | Cyclic cytidine monophosphate stimulates DNA synthesis by bovine mammary tissue in vitro. | 1987 | Cell Biol. Int. Rep. | pmid:2820591 |
Yen A et al. | Control of HL-60 monocytic differentiation. Different pathways and uncoupled expression of differentiation markers. | 1987 | Exp. Cell Res. | pmid:3023118 |
Polack A et al. | Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells. | 1987 | EMBO J. | pmid:3691477 |
Nakagawa Y and Perentes E | Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid. | 1987 | Ophthalmic Res. | pmid:3696696 |
Engelmann GL et al. | Effect of sodium butyrate on primary cultures of adult rat hepatocytes. | 1987 | In Vitro Cell. Dev. Biol. | pmid:2880833 |
Janati-Idrissi R et al. | [Selection of mutants of Clostridium acetobutylicum defective in production of acetone]. | 1987 May-Jun | Ann. Inst. Pasteur Microbiol. | pmid:3620201 |
Edsbäcker S et al. | Metabolic acetal splitting of budesonide. A novel inactivation pathway for topical glucocorticoids. | 1987 May-Jun | Drug Metab. Dispos. | pmid:2886320 |
Galenko-IaroshevckiÄ PA et al. | [Complex formation of lithium hydroxybutyrate with ions of Na+, K+, Ba2+, Mg2+, and Ca2+]. | 1987 Nov-Dec | Farmakol Toksikol | pmid:3436425 |
Bergeret M et al. | Immunomodulatory effects of arginine butyrate. | 1987 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:3140599 |
Hamasaki Y et al. | Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. | 1988 | Nippon Ketsueki Gakkai Zasshi | pmid:3144111 |
Kan YY et al. | Effects of polar organic compounds on gynecologic cancers. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3224317 |
Clouet PM and Bourre JM | Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. | 1988 | J. Neurochem. | pmid:3361304 |
Salam S | Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. | 1988 | Pak J Pharm Sci | pmid:16414615 |
Staecker JL et al. | Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture. | 1988 | J. Cell. Physiol. | pmid:2899578 |
Almlöf I et al. | Induction of basophilic differentiation in the human basophilic cell line KU812. | 1988 | Scand. J. Immunol. | pmid:2973655 |
Zhu XZ and Chuang DM | Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. | 1988 | J. Neurochem. | pmid:2826684 |
Rossi JF et al. | Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. | 1988 | Cancer Res. | pmid:2830017 |
Takeyasu K et al. | Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. | 1988 | J. Biol. Chem. | pmid:2831227 |
Sorimachi K | Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. | 1988 | Cell Biochem. Funct. | pmid:2832093 |
Sack TL et al. | Cyclic-AMP-stimulated synthesis and release of carcinoembryonic antigen by pancreatic cancer cells. | 1988 | Int. J. Pancreatol. | pmid:2834472 |
Pennypacker KR et al. | Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines. | 1988 | J. Neurochem. | pmid:2834519 |
Murray SA and Taylor F | Dibutyryl cyclic AMP modulation of gap junctions in SW-13 human adrenal cortical tumor cells. | 1988 | Am. J. Anat. | pmid:2835894 |
Spiegel S | Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin. | 1988 | Biochim. Biophys. Acta | pmid:2835987 |
Sorimachi K et al. | Requirement of serum pretreatment for induction of alkaline phosphatase activity with prednisolone, butyrate, dibutyryl cyclic adenosine monophosphate and NaCl in human liver cells continuously cultured in serum-free medium. | 1988 | Cell Struct. Funct. | pmid:2836073 |
Nishimura J et al. | Regulation of biosynthesis and phosphorylation of P210bcr/abl protein during differentiation induction of K 562 cells. | 1988 | Leuk. Res. | pmid:2464113 |
Baskova IP et al. | Thrombolytic agents of the preparation from the medicinal leeches. | 1988 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2459014 |
Boerner P and Saier MH | Effects of 5-azacytidine, sodium butyrate, and phorbol esters on amino acid transport system A in a kidney epithelial cell line, MDCK: evidence for multiple mechanisms of regulation. | 1988 | J. Cell. Physiol. | pmid:2459137 |
Burns LJ et al. | Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. | 1988 | Blood | pmid:2460154 |
Inhorn L et al. | Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. | 1988 | Blood | pmid:3128344 |
Asher C and Garty H | Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3140240 |
Spotti D et al. | Intermediary metabolism and glycemic control in insulin-dependent diabetic uremic patients treated by continuous peritoneal dialysis. | 1988 | Nephron | pmid:3041295 |
Fischkoff SA | Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions. | 1988 | Leuk. Res. | pmid:3184985 |
Takano M et al. | Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3186708 |
Januszewicz E et al. | Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. | 1988 | Med Oncol Tumor Pharmacother | pmid:3193830 |
Rhoads DB et al. | Evidence for expression of the facilitated glucose transporter in rat hepatocytes. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3194405 |
Brass EP and Beyerinck RA | Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. | 1988 | Biochem. J. | pmid:3134008 |
Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
Graham KA and Buick RN | Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. | 1988 | J. Cell. Physiol. | pmid:3294239 |
Durix A and Jean-Blain C | [Influence of fasting and the dietary lipid content on ketogenesis in isolated rabbit hepatocytes]. | 1988 | Reprod Nutr Dev | pmid:3254599 |
Nakagawa T et al. | Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. | 1988 | Cancer Res. | pmid:3258183 |
Filippovich IV et al. | Effect of the inducers of cellular differentiation and of ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. | 1988 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3258296 |
Gladhaug IP et al. | Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes. | 1988 | Cancer Res. | pmid:3263190 |
Yeger H et al. | Phenotypic and molecular characterization of inducible human neuroblastoma cell lines. | 1988 | Differentiation | pmid:3243386 |
Chatham J et al. | Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. | 1988 | FEBS Lett. | pmid:3169268 |
Albertini S et al. | The in vitro porcine brain tubulin assembly assay: effects of a genotoxic carcinogen (aflatoxin B1), eight tumor promoters and nine miscellaneous substances. | 1988 | Mutat. Res. | pmid:3173378 |
Gressner AM and Haarmann R | Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). | 1988 | Biochem. Pharmacol. | pmid:3178890 |
Vernia P et al. | Organic anions and the diarrhea of inflammatory bowel disease. | 1988 | Dig. Dis. Sci. | pmid:3180970 |
Leith JT | Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine. | 1988 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:3182335 |
Chang CC et al. | Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3066455 |
Campbell M and Chader GJ | Retinoblastoma cells in tissue culture. | 1988 | Ophthalmic Paediatr Genet | pmid:3068600 |
Ohwaki K | [High carboxylic acid level in the gingival crevicular fluid (GCF) of the patients with advanced periodontal disease]. | 1988 | Nihon Shishubyo Gakkai Kaishi | pmid:3078007 |
Herold KM and Rothberg PG | Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. | 1988 | Oncogene | pmid:3078950 |
Hidal JT and Kaplan MM | Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. | 1988 | Metab. Clin. Exp. | pmid:2838733 |
Courtin F et al. | Induction of type II 5'-deiodinase activity by cyclic adenosine 3', 5'-monophosphate in cultured rat astroglial cells. | 1988 | Endocrinology | pmid:2841100 |
Langdon SP et al. | Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines. | 1988 | Cancer Res. | pmid:3167862 |
Rodgers RJ et al. | Secretion of progesterone and prostaglandins by cells of bovine corpora lutea from three stages of the luteal phase. | 1988 | J. Endocrinol. | pmid:2842428 |
Kisauzi DN and Leek BF | Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. | 1988 | J. Comp. Pathol. | pmid:3417915 |
Bidet M et al. | Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. | 1988 | Biochim. Biophys. Acta | pmid:3342236 |
Davidson AM and Halestrap AP | Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. | 1988 | Biochem. J. | pmid:2845949 |
Yusta B et al. | Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate. | 1988 | J. Neurochem. | pmid:2846786 |
Yokochi T et al. | Effect of activation of the Epstein-Barr virus genome on expression of B cell differentiation antigens of Burkitt's lymphoma lines. | 1988 | Microbiol. Immunol. | pmid:2850450 |
Morise T et al. | Biological activity of partially purified digitalis-like substance and Na-K-ATPase inhibitor in rats. | 1988 | Jpn. Circ. J. | pmid:2852264 |
Ortiz-Caro J et al. | Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. | 1988 | Endocrinology | pmid:2836168 |
Li JS and Cheng YC | Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. | 1988 | Virus Genes | pmid:2852412 |
Prasad S and Thakur MK | Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. | 1988 | Biochem. Int. | pmid:3365268 |
Niles RM et al. | The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. | 1988 | Cancer Invest. | pmid:3365571 |
Leith JT | Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. | 1988 | J. Natl. Cancer Inst. | pmid:3367384 |
Cattini PA et al. | Effect of butyrate on thyroid hormone-mediated gene expression in rat pituitary tumour cells. | 1988 | Mol. Cell. Endocrinol. | pmid:3371552 |
Leith JT et al. | Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. | 1988 | Radiat. Res. | pmid:3375444 |
Joshi SS et al. | Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. | 1988 | Cancer Detect. Prev. | pmid:3390859 |
Kamech N and Seif R | Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. | 1988 | Exp. Cell Res. | pmid:3391246 |
Reading CL et al. | Analysis of cell surface glycoprotein changes related to hematopoietic differentiation. | 1988 | J. Cell. Biochem. | pmid:3392108 |
Tatsuka M et al. | An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. | 1988 | Exp. Cell Res. | pmid:3409976 |
Drucker DJ et al. | Proglucagon gene expression and posttranslational processing in a hamster islet cell line. | 1988 | Endocrinology | pmid:3416818 |
Szabad J et al. | The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. | 1988 | Mol. Gen. Genet. | pmid:3422705 |
Giancotti V et al. | Butyrate effect on nuclear proteins of two Chinese hamster cell lines. | 1988 | Exp. Cell Res. | pmid:3335229 |
Spector R | Fatty acid transport through the blood-brain barrier. | 1988 | J. Neurochem. | pmid:3335863 |
Virtanen I et al. | Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. | 1988 | Lab. Invest. | pmid:3141718 |