butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Dentin, Secondary D003809 2 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diarrhea D003967 32 associated lipids
Disease Models, Animal D004195 4 associated lipids
Diverticulitis D004238 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Dysentery D004403 4 associated lipids
Edema D004487 152 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Neu J and Bernstein H Update on host defense and immunonutrients. 2002 Clin Perinatol pmid:11917739
Yang J et al. Modifying the chain-length selectivity of the lipase from Burkholderia cepacia KWI-56 through in vitro combinatorial mutagenesis in the substrate-binding site. 2002 Protein Eng. pmid:11917151
Kamitani H et al. Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. 2002 Neuro-oncology pmid:11916500
Decruse SW and Seeni S Ammonium nitrate in the culture medium influences regeneration potential of cryopreserved shoot tips of Holostemma annulare. 2002 Jan-Feb Cryo Letters pmid:11912508
Van Reeth T et al. Stimulation of the alpha-fetoprotein promoter by unliganded thyroid hormone receptor in association with protein deacetylation. 2002 Mol. Cell. Endocrinol. pmid:11911950
Cessna AJ and Grover R Exposure of ground-rig applicators to the herbicide bromoxynil applied as a 1:1 mixture of butyrate and octanoate. 2002 Arch. Environ. Contam. Toxicol. pmid:11910467
Sawa H et al. Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. 2001 Brain Tumor Pathol pmid:11908866
Jones SL et al. Correlation of long-range membrane order with temperature-dependent growth characteristics of parent and a cold-sensitive, branched-chain-fatty-acid-deficient mutant of Listeria monocytogenes. 2002 Arch. Microbiol. pmid:11907677
Jalc D and Ceresnáková Z Effect of plant oils and aspartate on rumen fermentation in vitro. 2001 J Anim Physiol Anim Nutr (Berl) pmid:11906562
Faust D et al. Butyrate and the cytokine-induced alpha1-proteinase inhibitor release in intestinal epithelial cells. 2001 Eur. J. Clin. Invest. pmid:11903492
Izco JM et al. Development of a CE method to analyze organic acids in dairy products: application to study the metabolism of heat-shocked spores. 2002 J. Agric. Food Chem. pmid:11902910
Tyagi S et al. Mechanism of n-butyrate uptake in the human proximal colonic basolateral membranes. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11897627
Domon-Dell C et al. Stimulation of the intestinal Cdx2 homeobox gene by butyrate in colon cancer cells. 2002 Gut pmid:11889074
Park NS et al. The crystal structure of KR-21042, an analgesic capsaicinoid. 2002 Arch. Pharm. Res. pmid:11887880
Lebrun-Garcia A et al. Questioning the role of salicylic acid and cytosolic acidification in mitogen-activated protein kinase activation induced by cryptogein in tobacco cells. 2002 Planta pmid:11882949
Cuff MA et al. Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1. 2002 J. Physiol. (Lond.) pmid:11882670
Nakagawa J et al. Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney. 2002 J. Biol. Chem. pmid:11882650
Farajzadeh M and Mardani A Analysis of residual solvents in ampicillin powder by headspace spectrophotometric method. 2002 Anal Sci pmid:11874121
Shin R et al. Influence of intestinal anaerobes and organic acids on the growth of enterohaemorrhagic Escherichia coli O157:H7. 2002 J. Med. Microbiol. pmid:11871614
Hergenhahn M et al. The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells. 2002 Mol. Carcinog. pmid:11870879
Shen Z et al. [The effects of sodium butyrate on proliferation, differentiation and apoptosis in immortalized esophageal epithelial cells]. 2001 Zhonghua Bing Li Xue Za Zhi pmid:11866968
Andoh A et al. Sodium butyrate enhances complement-mediated cell injury via down-regulation of decay-accelerating factor expression in colonic cancer cells. 2002 Cancer Immunol. Immunother. pmid:11862418
Hyman R Lack of a consistent relationship between demethylation of the CD44 promoter and CD44 expression. 2002 Immunogenetics pmid:11862392
Vien J et al. trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and (+/-)-trans-2-aminomethylcyclopropanecarboxylic acid ((+/-)-TAMP) can differentiate rat rho3 from human rho1 and rho2 recombinant GABA(C) receptors. 2002 Br. J. Pharmacol. pmid:11861315
Hulin SJ et al. Sulphide-induced energy deficiency in colonic cells is prevented by glucose but not by butyrate. 2002 Aliment. Pharmacol. Ther. pmid:11860416
Fang HH and Liu H Effect of pH on hydrogen production from glucose by a mixed culture. 2002 Bioresour. Technol. pmid:11858207
Giermasz A et al. Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice. 2002 Int. J. Cancer pmid:11857349
Kato K et al. Identification and characterization of Marek's disease virus serotype 1 (MDV1) ICP22 gene product: MDV1 ICP22 transactivates the MDV1 ICP27 promoter synergistically with MDV1 ICP4. 2002 Vet. Microbiol. pmid:11856580
Tang CL et al. Development of a chronic colonic intubation model in rats for the study of luminal factors in colonic diseases. 2002 Dis. Colon Rectum pmid:11852341
Kukushkin AN et al. Downregulation of c-fos gene transcription in cells transformed by E1A and cHa-ras oncogenes: a role of sustained activation of MAP/ERK kinase cascade and of inactive chromatin structure at c-fos promoter. 2002 Oncogene pmid:11850800
Vidyasagar S and Ramakrishna BS Effects of butyrate on active sodium and chloride transport in rat and rabbit distal colon. 2002 J. Physiol. (Lond.) pmid:11850510
Huang YL et al. Production of carboxylic acids from hydrolyzed corn meal by immobilized cell fermentation in a fibrous-bed bioreactor. 2002 Bioresour. Technol. pmid:11848378
Ramos MG et al. Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide. 2002 Braz. J. Med. Biol. Res. pmid:11847519
Couchie D et al. In vitro differentiation of WB-F344 rat liver epithelial cells into the biliary lineage. 2002 Differentiation pmid:11841479
Menes RJ and Muxí L Anaerobaculum mobile sp. nov., a novel anaerobic, moderately thermophilic, peptide-fermenting bacterium that uses crotonate as an electron acceptor, and emended description of the genus Anaerobaculum. 2002 Int. J. Syst. Evol. Microbiol. pmid:11837298
Waldron MR et al. Volatile fatty acid metabolism by epithelial cells isolated from different areas of the ewe rumen. 2002 J. Anim. Sci. pmid:11831526
Monteils V et al. Kinetics of ruminal degradation of wheat and potato starches in total mixed rations. 2002 J. Anim. Sci. pmid:11831523
Zhou DC et al. Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. 2002 Blood pmid:11830487
Salomone B et al. In vitro effects of cholesteryl butyrate solid lipid nanospheres as a butyric acid pro-drug on melanoma cells: evaluation of antiproliferative activity and apoptosis induction. 2000 Clin. Exp. Metastasis pmid:11827070
Sasahara Y et al. Suppression of promoter-dependent transcriptional activity of inducible nitric oxide synthase by sodium butyrate in colon cancer cells. 2002 Cancer Lett. pmid:11825662
Sourlingas TG et al. Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expression of the linker histone variant, H1 degrees. 2001 Eur. J. Cell Biol. pmid:11824792
Schaffer S et al. Changes in protein synthesis and identification of proteins specifically induced during solventogenesis in Clostridium acetobutylicum. 2002 Electrophoresis pmid:11824611
Ha JH et al. Modulation of radioligand binding to the GABA(A)-benzodiazepine receptor complex by a new component from Cyperus rotundus. 2002 Biol. Pharm. Bull. pmid:11824542
Kang HW et al. Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis. 2002 Biol. Pharm. Bull. pmid:11824536
Säemann MD et al. Bacterial metabolite interference with maturation of human monocyte-derived dendritic cells. 2002 J. Leukoc. Biol. pmid:11818444
Pandolfini T et al. Optimisation of transgene action at the post-transcriptional level: high quality parthenocarpic fruits in industrial tomatoes. 2002 BMC Biotechnol. pmid:11818033
Khorasani GR et al. Effects of substituting barley grain with corn on ruminal fermentation characteristics, milk yield, and milk composition of Holstein cows. 2001 J. Dairy Sci. pmid:11814032
Miller DN and Varel VH In vitro study of the biochemical origin and production limits of odorous compounds in cattle feedlots. 2001 J. Anim. Sci. pmid:11811446
Suenaga M et al. Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells. 2002 Int. J. Cancer pmid:11807787
Lührs H et al. Modulation of HMG-N2 binding to chromatin by butyrate-induced acetylation in human colon adenocarcinoma cells. 2002 Int. J. Cancer pmid:11807779
Wasserman L et al. The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line. 2002 Am J Dermatopathol pmid:11803275
Choi J et al. Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals. 2002 J Ethnopharmacol pmid:11801382
Jordan IK et al. Constant relative rate of protein evolution and detection of functional diversification among bacterial, archaeal and eukaryotic proteins. 2001 Genome Biol. pmid:11790256
Nancey S et al. [Colonic microflora and cancer]. 2001 Gastroenterol. Clin. Biol. pmid:11787385
Chopin V et al. Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells. 2002 Br. J. Pharmacol. pmid:11786482
Fabianowska-Majewska K et al. Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation. 2000 Adv. Exp. Med. Biol. pmid:11783512
Karagül-Yüceer Y et al. Volatile flavor components of stored nonfat dry milk. 2002 J. Agric. Food Chem. pmid:11782199
Bender A et al. Colonic fermentation as affected by antibiotics and acidic pH: Application of an in vitro model. 2001 Z Gastroenterol pmid:11778150
Tshiyombo TD and Oulton MR Comparative effects of chronic exposure to glucose or sodium butyrate on surfactant development in fetal rabbits. 2001 J Perinat Med pmid:11776678
Bordonaro M et al. Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. 2002 Int. J. Cancer pmid:11774242
Hashimoto H et al. [The occurrence of a reductase of delta2-carboxylic acids in Clostridium kluyveri with a stereospecificity different from that of butyryl-CoA dehydrogenase (author's transl)]. 1975 Hoppe-Seyler's Z. Physiol. Chem. pmid:1176088
Kang HO et al. Cometabolic biosynthesis of copolyesters consisting of 3-hydroxyvalerate and medium-chain-length 3-hydroxyalkanoates by Pseudomonas sp. DSY-82. 2001 Antonie Van Leeuwenhoek pmid:11759051
Pácha J et al. Effect of cellular differentiation on 11beta-hydroxysteroid dehydrogenase activity in the intestine. 2002 Steroids pmid:11755176
O'Donnell JM et al. Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart. 2002 Biophys. J. pmid:11751291
Liu HL and Anthonsen T Enantiopure building blocks for chiral drugs from racemic mixtures of secondary alcohols by combination of lipase catalysis and Mitsunobu esterification. 2002 Chirality pmid:11748796
Giermasz A et al. Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice. 2002 Jan-Feb Oncol. Rep. pmid:11748483
Dienel GA et al. Local uptake of (14)C-labeled acetate and butyrate in rat brain in vivo during spreading cortical depression. 2001 J. Neurosci. Res. pmid:11746406
Fukuda M et al. Prebiotic treatment of experimental colitis with germinated barley foodstuff: a comparison with probiotic or antibiotic treatment. 2002 Int. J. Mol. Med. pmid:11744999
Araki Y et al. Oral administration of a product derived from Clostridium butyricum in rats. 2002 Int. J. Mol. Med. pmid:11744996
Honecker VH and Coper H [Stability of amphetaminil. 1. In-vitro studies]. 1975 Arzneimittelforschung pmid:1174051
Paulukat J et al. Expression and release of IL-18 binding protein in response to IFN-gamma. 2001 J. Immunol. pmid:11739524
Kegel KB et al. Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription. 2002 J. Biol. Chem. pmid:11739372
Fang HH and Yu H Mesophilic acidification of gelatinaceous wastewater. 2002 J. Biotechnol. pmid:11738717
Vatin AE and Filatov PP [Pharmacokinetics of C14-olivomycin in the body of mice with lymphosarcoma (L10-1 strain)]. 1975 Antibiotiki pmid:1173211
Holdaway-Clarke TL et al. Cytoplasmic acidification with butyric acid does not alter the ionic conductivity of plasmodesmata. 2001 Protoplasma pmid:11732057
Daubeuf S et al. Differential regulation of gamma-glutamyltransferase mRNAs in four human tumour cell lines. 2001 Biochim. Biophys. Acta pmid:11731087
Guardiola AR and Yao TP Molecular cloning and characterization of a novel histone deacetylase HDAC10. 2002 J. Biol. Chem. pmid:11726666
Reynaert R et al. Influence of serum free fatty acid levels on growth hormone secretion in lactating cows. 1975 J. Endocrinol. pmid:1172520
Ugrinova I et al. In vivo acetylation of HMG1 protein enhances its binding affinity to distorted DNA structures. 2001 Biochemistry pmid:11724579
Brokaw L et al. Supplemental soybean oil or corn for beef heifers grazing summer pasture: effects on forage intake, ruminal fermentation, and site and extent of digestion. 2001 J. Anim. Sci. pmid:11721851
Henney JE Cyberpharmacies and the role of the US Food And Drug Administration. 2001 Jan-Mar J. Med. Internet Res. pmid:11720945
Osada H et al. Heterogeneous transforming growth factor (TGF)-beta unresponsiveness and loss of TGF-beta receptor type II expression caused by histone deacetylation in lung cancer cell lines. 2001 Cancer Res. pmid:11719467
Cao XX et al. Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. 2001 Am. J. Respir. Cell Mol. Biol. pmid:11713097
Tuleu C et al. Colonic delivery of sodium butyrate via oral route: acrylic coating design of pellets and in vivo evaluation in rats. 2001 Methods Find Exp Clin Pharmacol pmid:11712644
Pérez G et al. Disturbance of cellular iron uptake and utilisation by aluminium. 2001 J. Inorg. Biochem. pmid:11709209
Frederich M and Balschi JA The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart. 2002 J. Biol. Chem. pmid:11707445
Gassull MA and Cabré E Nutrition in inflammatory bowel disease. 2001 Curr Opin Clin Nutr Metab Care pmid:11706295
Amin HM et al. Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). 2001 Br. J. Haematol. pmid:11703323
Santini V et al. Searching for the magic bullet against cancer: the butyrate saga. 2001 Leuk. Lymphoma pmid:11699392
Dunphy CH et al. Acute promyelocytic leukemia, hypogranular variant, with uncharacteristic staining with chloroacetate esterase. 2001 Leuk. Lymphoma pmid:11699210
Loffing-Cueni D et al. Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. 2001 Am. J. Physiol., Cell Physiol. pmid:11698247
Resta-Lenert S et al. Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. 2001 Am. J. Physiol., Cell Physiol. pmid:11698242
Amano J et al. Comparative study of glycosyltransferase activities in Caco-2 cells before and after enterocytic differentiation using lectin-affinity high-performance liquid chromatography. 2001 Arch. Biochem. Biophys. pmid:11697856
Zheng X et al. Synergistic effects of clinically achievable concentrations of 12-O-tetradecanoylphorbol-13-acetate in combination with all-trans retinoic acid, 1alpha,25-dihydroxyvitamin D3, and sodium butyrate on differentiation in HL-60 cells. 2000 Oncol. Res. pmid:11697820
Sultanova N et al. Antioxidant and antimicrobial activities of Tamarix ramosissima. 2001 J Ethnopharmacol pmid:11694365
Fujita M et al. Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. 2001 Cancer Res. pmid:11691783
Onori L et al. N-Butyrate rectal transport in cirrhotic patients. 2001 Dig. Dis. Sci. pmid:11680580
Gaschott T et al. Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor. 2001 Biochem. Biophys. Res. Commun. pmid:11676498
Tsapali DS et al. mRNA levels of the differentiation-associated linker histone variant H1 zero in mitotically active and postmitotic senescent human diploid fibroblast cell populations. 2001 Exp. Gerontol. pmid:11672986
Terao Y et al. Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells. 2001 Int. J. Cancer pmid:11668507