butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Carcinoma, Small Cell D018288 21 associated lipids
Sarcoma 180 D012510 21 associated lipids
Poultry Diseases D011201 21 associated lipids
HIV Infections D015658 20 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lymphoma D008223 18 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Periodontal Diseases D010510 15 associated lipids
Radiation Injuries D011832 14 associated lipids
Acidosis D000138 13 associated lipids
Ketosis D007662 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Hyperkinesis D006948 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Kaiser E and Weiss K [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. 1997 Arch Tierernahr pmid:9324922
Scannell JP et al. Antimetabolites produced by microorganisms. XIII. The synthesis and microbiological production of a novel amino acid, L-2-amino-4-(2-aminoethoxy) butanoic acid. 1976 J. Antibiot. pmid:931793
Engelhard HH et al. Molecular characterization of glioblastoma cell differentiation. 1997 Neurosurgery pmid:9316051
Dohi H et al. Intake stimulants in perennial ryegrass (Lolium perenne L.) fed to sheep. 1997 J. Dairy Sci. pmid:9313150
Hague A et al. bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. 1997 Int. J. Cancer pmid:9311611
Ishiguro K and Sartorelli AC Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin. 1997 Blood pmid:9310478
Birkett AM et al. Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. 1997 Eur J Clin Nutr pmid:9306090
Cuisset L et al. The effects of sodium butyrate on transcription are mediated through activation of a protein phosphatase. 1997 J. Biol. Chem. pmid:9305863
Chénais B et al. Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels. 1997 Leukemia pmid:9305615
Lewis SJ and Heaton KW Increasing butyrate concentration in the distal colon by accelerating intestinal transit. 1997 Gut pmid:9301506
Ohno Y et al. Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9294201
Talley NA et al. Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial. 1997 Dis. Colon Rectum pmid:9293933
Medina V et al. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. 1997 Cancer Res. pmid:9288776
Chen ZJ and Pikaard CS Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance. 1997 Genes Dev. pmid:9284051
Kenyon E et al. Apical and basolateral membrane mechanisms that regulate pHi in bovine retinal pigment epithelium. 1997 Am. J. Physiol. pmid:9277343
De Visser H et al. Nutrient fluxes in splanchnic tissue of dairy cows: influence of grass quality. 1997 J. Dairy Sci. pmid:9276806
Humbert G et al. Method for the measurement of lipase activity in milk. 1997 J. Dairy Res. pmid:9275261
Simon B et al. Transient transcriptional activation of gastrin during sodium butyrate-induced differentiation of islet cells. 1997 Regul. Pept. pmid:9272626
Xiao H et al. Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner. 1997 Biochem. Biophys. Res. Commun. pmid:9268733
Nakano K et al. Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. 1997 J. Biol. Chem. pmid:9268365