butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
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Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fialova B et al. | Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine. | 2016 | Oncol. Rep. | pmid:27499010 |
| Foote AP and Freetly HC | Effect of abomasal butyrate infusion on net nutrient flux across the portal-drained viscera and liver of growing lambs. | 2016 | J. Anim. Sci. | pmid:27482683 |
| Terova G et al. | Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. | 2016 | PLoS ONE | pmid:27471849 |
| Jawed K et al. | Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. | 2016 | PLoS ONE | pmid:27466817 |
| Gargari G et al. | Consumption of a Bifidobacterium bifidum Strain for 4 Weeks Modulates Dominant Intestinal Bacterial Taxa and Fecal Butyrate in Healthy Adults. | 2016 | Appl. Environ. Microbiol. | pmid:27451450 |
| Teixeira C et al. | Effects of variety and steeping conditions on some barley components associated with colonic health. | 2016 | J. Sci. Food Agric. | pmid:27450418 |
| Longpré J et al. | Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs. | 2016 | J. Anim. Sci. | pmid:27065267 |
| Early JV et al. | Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. | 2016 | Antimicrob. Agents Chemother. | pmid:27044545 |
| He B et al. | Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. | 2016 | Animal | pmid:27040131 |
| Petry FS et al. | Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. | 2016 | Behav. Brain Res. | pmid:27025446 |
| Frycz BA et al. | Transcript level of AKR1C3 is down-regulated in gastric cancer. | 2016 | Biochem. Cell Biol. | pmid:27019068 |
| Li H et al. | Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. | 2016 | Brain Res. | pmid:27017959 |
| Ortega JF et al. | Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. | 2016 | Oncotarget | pmid:27013579 |
| Ng CH and Yang KL | Lipase in biphasic alginate beads as a biocatalyst for esterification of butyric acid and butanol in aqueous media. | 2016 | Enzyme Microb. Technol. | pmid:26672465 |
| Han A et al. | Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. | 2016 | J. Cell. Physiol. | pmid:26661480 |
| Tiwari P et al. | Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. | 2016 | Biochimie | pmid:26655363 |
| Valvassori SS et al. | Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. | 2016 | Psychiatry Res | pmid:26654753 |
| Junicke H et al. | Kinetic and thermodynamic control of butyrate conversion in non-defined methanogenic communities. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26403924 |
| Ayers LW et al. | Changes in dam and pup behavior following repeated postnatal exposure to a predator odor (TMT): A preliminary investigation in Long-Evans rats. | 2016 | Dev Psychobiol | pmid:26394891 |
| Russo R et al. | Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice. | 2016 | Pharmacol. Res. | pmid:26675718 |
| Reddy YS et al. | Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. | 2016 | J Oleo Sci | pmid:26666272 |
| Polycarpo GV et al. | Effects of lipid sources, lysophospholipids and organic acids in maize-based broiler diets on nutrient balance, liver concentration of fat-soluble vitamins, jejunal microbiota and performance. | 2016 | Br. Poult. Sci. | pmid:27494540 |
| Kim M et al. | Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity. | 2016 | Bioresour. Technol. | pmid:27474955 |
| Huang H et al. | Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. | 2016 | Cell. Mol. Immunol. | pmid:25683610 |
| Bastiaansen JA et al. | Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. | 2016 | Sci Rep | pmid:27150735 |
| Seki K et al. | Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. | 2016 | Apoptosis | pmid:26994613 |
| Zhang T et al. | Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. | 2016 | Nutrients | pmid:27886121 |
| Tochio T et al. | An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. | 2016 | PLoS ONE | pmid:27861621 |
| Tian H et al. | Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor. | 2016 | Molecules | pmid:27854343 |
| Neis EP et al. | Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. | 2016 | PLoS ONE | pmid:27835668 |
| Kong X et al. | Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. | 2016 | Bioresour. Technol. | pmid:26998799 |
| Zhu J et al. | Sodium butyrate modulates a methamphetamine-induced conditioned place preference. | 2017 | J. Neurosci. Res. | pmid:27426635 |
| Berni Canani R et al. | Specific Signatures of the Gut Microbiota and Increased Levels of Butyrate in Children Treated with Fermented Cow's Milk Containing Heat-Killed Lactobacillus paracasei CBA L74. | 2017 | Appl. Environ. Microbiol. | pmid:28733284 |
| Pelgrim CE et al. | Butyrate Reduces HFD-Induced Adipocyte Hypertrophy and Metabolic Risk Factors in Obese LDLr-/-.Leiden Mice. | 2017 | Nutrients | pmid:28686216 |
| Tsung AJ et al. | Methylation regulates HEY1 expression in glioblastoma. | 2017 | Oncotarget | pmid:28574840 |
| Wang L et al. | Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin-angiotensin system. | 2017 | J. Hypertens. | pmid:28509726 |
| Dou X et al. | Sodium butyrate improves porcine host defense peptide expression and relieves the inflammatory response upon Toll-like receptor 2 activation and histone deacetylase inhibition in porcine kidney cells. | 2017 | Oncotarget | pmid:28460447 |
| Asquith M et al. | Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis. | 2017 | pmid:28622455 | |
| Lucchetti D et al. | Differentiation Affects the Release of Exosomes from Colon Cancer Cells and Their Ability to Modulate the Behavior of Recipient Cells. | 2017 | Am. J. Pathol. | pmid:28619275 |
| Lu N et al. | Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:28602959 |
| Kumar P et al. | Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. | 2017 | Am. J. Physiol. Renal Physiol. | pmid:28566502 |
| Tian L et al. | Sodium butyrate improved intestinal immune function associated with NF-κB and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella). | 2017 | Fish Shellfish Immunol. | pmid:28546021 |
| Zhang L et al. | Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice. | 2017 | J. Cell. Biochem. | pmid:28109123 |
| Cueno ME et al. | Periodontal disease level-butyric acid putatively contributes to the ageing blood: A proposed link between periodontal diseases and the ageing process. | 2017 | Mech. Ageing Dev. | pmid:28108180 |
| Zhou D et al. | Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier. | 2017 | World J. Gastroenterol. | pmid:28104981 |
| Huang JC et al. | [Protective effect of histone acetylation against cortical injury in neonatal rats]. | 2017 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:28100329 |
| Albuquerque Filho MO et al. | Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats. | 2017 | Neuroscience | pmid:28089578 |
| Moens F et al. | Lactate- and acetate-based cross-feeding interactions between selected strains of lactobacilli, bifidobacteria and colon bacteria in the presence of inulin-type fructans. | 2017 | Int. J. Food Microbiol. | pmid:27810444 |
| Dong W et al. | Sodium butyrate activates NRF2 to ameliorate diabetic nephropathy possibly via inhibition of HDAC. | 2017 | J. Endocrinol. | pmid:27799462 |
| Wang YQ et al. | Enhancement of acetate productivity in a thermophilic (55 °C) hollow-fiber membrane biofilm reactor with mixed culture syngas (H/CO) fermentation. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28110397 |