butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Facial Injuries D005151 1 associated lipids
Fatty Liver D005234 48 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhoids D006484 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Hamasaki Y et al. Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. 1988 Nippon Ketsueki Gakkai Zasshi pmid:3144111
Kan YY et al. Effects of polar organic compounds on gynecologic cancers. 1988 Zhonghua Yi Xue Za Zhi (Taipei) pmid:3224317
Clouet PM and Bourre JM Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. 1988 J. Neurochem. pmid:3361304
Salam S Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. 1988 Pak J Pharm Sci pmid:16414615
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Zhu XZ and Chuang DM Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. 1988 J. Neurochem. pmid:2826684
Hutt-Taylor SR et al. Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60. 1988 Blood pmid:2446679
Rossi JF et al. Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. 1988 Cancer Res. pmid:2830017
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Sorimachi K Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. 1988 Cell Biochem. Funct. pmid:2832093
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Baskova IP et al. Thrombolytic agents of the preparation from the medicinal leeches. 1988 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:2459014
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Burns LJ et al. Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. 1988 Blood pmid:2460154
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Inhorn L et al. Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. 1988 Blood pmid:3128344
Asher C and Garty H Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3140240
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Fischkoff SA Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions. 1988 Leuk. Res. pmid:3184985
Takano M et al. Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3186708
Januszewicz E et al. Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. 1988 Med Oncol Tumor Pharmacother pmid:3193830
Rhoads DB et al. Evidence for expression of the facilitated glucose transporter in rat hepatocytes. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3194405
Brass EP and Beyerinck RA Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. 1988 Biochem. J. pmid:3134008
Toscani A et al. Molecular analysis of sodium butyrate-induced growth arrest. 1988 Oncogene Res. pmid:3144695
Graham KA and Buick RN Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. 1988 J. Cell. Physiol. pmid:3294239
Durix A and Jean-Blain C [Influence of fasting and the dietary lipid content on ketogenesis in isolated rabbit hepatocytes]. 1988 Reprod Nutr Dev pmid:3254599
Nakagawa T et al. Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. 1988 Cancer Res. pmid:3258183
Filippovich IV et al. Effect of the inducers of cellular differentiation and of ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. 1988 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:3258296
Gladhaug IP et al. Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes. 1988 Cancer Res. pmid:3263190
Yeger H et al. Phenotypic and molecular characterization of inducible human neuroblastoma cell lines. 1988 Differentiation pmid:3243386
Chatham J et al. Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. 1988 FEBS Lett. pmid:3169268
Kéri G et al. Comparison of the tyrosine kinase activity with the proliferation rate in human colon solid tumors and tumor cell lines. 1988 Tumour Biol. pmid:3206110
Albertini S et al. The in vitro porcine brain tubulin assembly assay: effects of a genotoxic carcinogen (aflatoxin B1), eight tumor promoters and nine miscellaneous substances. 1988 Mutat. Res. pmid:3173378
Nishiya I et al. Relationship between changes of the steroid receptor and synchronization in human endometrial adenocarcinoma cells in vitro. 1988 Cytometry pmid:3208623
Yusta B et al. Mechanism of L-triiodothyronine (T3) uptake by glial C6 cells: regulation by butyrate. 1988 Mol. Cell. Endocrinol. pmid:3208994
Gressner AM and Haarmann R Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). 1988 Biochem. Pharmacol. pmid:3178890
Vernia P et al. Organic anions and the diarrhea of inflammatory bowel disease. 1988 Dig. Dis. Sci. pmid:3180970
Leith JT Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine. 1988 Int. J. Radiat. Oncol. Biol. Phys. pmid:3182335
Chang CC et al. Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. 1988 Zhonghua Yi Xue Za Zhi (Taipei) pmid:3066455
Ortiz-Caro J et al. Proliferation and differentiation are not directly related to H1(0) accumulation in cultured glial cells. 1988 Brain Res. pmid:3219583
Ohwaki K [High carboxylic acid level in the gingival crevicular fluid (GCF) of the patients with advanced periodontal disease]. 1988 Nihon Shishubyo Gakkai Kaishi pmid:3078007
Takenaga K et al. Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells. 1988 Mol. Cell. Biol. pmid:3221870
Herold KM and Rothberg PG Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. 1988 Oncogene pmid:3078950
Maddox AM and Haddox MK Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells. 1988 Exp. Cell Biol. pmid:2903078
Hellweg R et al. Nerve growth factor synthesis in cultured rat iris: modulation by endogenous transmitter substances. 1988 Exp. Cell Res. pmid:2844567
Hidal JT and Kaplan MM Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. 1988 Metab. Clin. Exp. pmid:2838733
Laeng H et al. Participation of mitochondrial proliferation in morphological differentiation of murine mastocytoma cells. 1988 Exp. Cell Res. pmid:2844569
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Ryan MP and Higgins PJ Cytoarchitecture of Kirsten sarcoma virus-transformed rat kidney fibroblasts: butyrate-induced reorganization within the actin microfilament network. 1988 J. Cell. Physiol. pmid:2844835
Langdon SP et al. Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines. 1988 Cancer Res. pmid:3167862
Rodgers RJ et al. Secretion of progesterone and prostaglandins by cells of bovine corpora lutea from three stages of the luteal phase. 1988 J. Endocrinol. pmid:2842428
Kaneko Y et al. Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. 1988 Biochem. Biophys. Res. Commun. pmid:2843181
Sutherland GR et al. A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures. 1988 Cytogenet. Cell Genet. pmid:2843323
Powers AC et al. Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone. 1988 Diabetes pmid:2843409
Kisauzi DN and Leek BF Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. 1988 J. Comp. Pathol. pmid:3417915
Bidet M et al. Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. 1988 Biochim. Biophys. Acta pmid:3342236
Davidson AM and Halestrap AP Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. 1988 Biochem. J. pmid:2845949
Yusta B et al. Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate. 1988 J. Neurochem. pmid:2846786
Yokochi T et al. Effect of activation of the Epstein-Barr virus genome on expression of B cell differentiation antigens of Burkitt's lymphoma lines. 1988 Microbiol. Immunol. pmid:2850450
Morise T et al. Biological activity of partially purified digitalis-like substance and Na-K-ATPase inhibitor in rats. 1988 Jpn. Circ. J. pmid:2852264
Ortiz-Caro J et al. Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. 1988 Endocrinology pmid:2836168
Li JS and Cheng YC Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. 1988 Virus Genes pmid:2852412
Prasad S and Thakur MK Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. 1988 Biochem. Int. pmid:3365268
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Niles RM et al. The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. 1988 Cancer Invest. pmid:3365571
Leith JT Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. 1988 J. Natl. Cancer Inst. pmid:3367384
Cattini PA et al. Effect of butyrate on thyroid hormone-mediated gene expression in rat pituitary tumour cells. 1988 Mol. Cell. Endocrinol. pmid:3371552
Leith JT et al. Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. 1988 Radiat. Res. pmid:3375444
Kamech N and Seif R Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. 1988 Exp. Cell Res. pmid:3391246
Reading CL et al. Analysis of cell surface glycoprotein changes related to hematopoietic differentiation. 1988 J. Cell. Biochem. pmid:3392108
Staecker JL and Pitot HC The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. 1988 Arch. Biochem. Biophys. pmid:2895606
Tatsuka M et al. An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. 1988 Exp. Cell Res. pmid:3409976
Drucker DJ et al. Proglucagon gene expression and posttranslational processing in a hamster islet cell line. 1988 Endocrinology pmid:3416818
Chan WC et al. Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents. 1988 Blood pmid:2961380
Szabad J et al. The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. 1988 Mol. Gen. Genet. pmid:3422705
Giancotti V et al. Butyrate effect on nuclear proteins of two Chinese hamster cell lines. 1988 Exp. Cell Res. pmid:3335229
Spector R Fatty acid transport through the blood-brain barrier. 1988 J. Neurochem. pmid:3335863
Effects of short-chain fatty acids on a human colon carcinoma cell line. 1988 Nutr. Rev. pmid:3340339
Hallows KR et al. Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells. 1988 Radiat. Res. pmid:3340722
Berry RD and Paraskeva C Expression of carcinoembryonic antigen by adenoma and carcinoma derived epithelial cell lines: possible marker of tumour progression and modulation of expression by sodium butyrate. 1988 Carcinogenesis pmid:3345582
Annunziato AT et al. Treatment with sodium butyrate inhibits the complete condensation of interphase chromatin. 1988 Chromosoma pmid:3349872
Leith JT Effects of sodium butyrate and 3-aminobenzamide on survival of Chinese hamster HA-1 cells after X irradiation. 1988 Radiat. Res. pmid:3353504
Reynier MO et al. Influence of lipid-rich diets on intestinal cholesterol uptake. 1988 Ann. Nutr. Metab. pmid:3355108
Zhang DE and Nelson DA Histone acetylation in chicken erythrocytes. Rates of deacetylation in immature and mature red blood cells. 1988 Biochem. J. pmid:3355515
Virtanen I et al. Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. 1988 Lab. Invest. pmid:3141718