| MeSH term | MeSH ID | Detail |
|---|---|---|
| Enterocolitis, Pseudomembranous | D004761 | 8 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Facial Injuries | D005151 | 1 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fragile X Syndrome | D005600 | 5 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glycogen Storage Disease Type II | D006009 | 2 associated lipids |
| Granuloma, Lethal Midline | D006103 | 2 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hemorrhoids | D006484 | 2 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Campbell M and Chader GJ | Retinoblastoma cells in tissue culture. | 1988 | Ophthalmic Paediatr Genet | pmid:3068600 |
| Nakagawa Y and Perentes E | Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid. | 1987 | Ophthalmic Res. | pmid:3696696 |
| Kaplan BA and Trimber CJ | Corneal response to extended wear of CAB contact lenses in aphakia. | 1980 | Ophthalmology | pmid:7393534 |
| Dupuis A et al. | Prospective for biodegradable microstructured optical fibers. | 2007 | Opt Lett | pmid:17186033 |
| Zilm PS et al. | Changes in growth and polyglucose synthesis in response to fructose metabolism by Fusobacterium nucleatum grown in continuous culture. | 2003 | Oral Microbiol. Immunol. | pmid:12823803 |
| Harris JI et al. | Molecular mediators of Porphyromonas gingivalis-induced T-cell apoptosis. | 2002 | Oral Microbiol. Immunol. | pmid:12121472 |
| Lam WH et al. | Identification of a novel beta-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A. | 2008 | Org. Biomol. Chem. | pmid:18480903 |
| Komoda T et al. | Biosynthesis of tetrapetalones. | 2007 | Org. Biomol. Chem. | pmid:17571192 |
| Walz AJ et al. | Synthesis and studies of catechol-containing mycobactin S and T analogs. | 2007 | Org. Biomol. Chem. | pmid:17571193 |
| Anderson NA et al. | Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. | 2016 | Org. Biomol. Chem. | pmid:27226381 |
| Sunnam SK et al. | Bicyclic sigma receptor ligands by stereoselective Dieckmann analogous cyclization of piperazinebutyrate. | 2010 | Org. Biomol. Chem. | pmid:20556273 |
| Cao CL et al. | Pyrrolidine-thiourea as a bifunctional organocatalyst: highly enantioselective Michael addition of cyclohexanone to nitroolefins. | 2006 | Org. Lett. | pmid:16805512 |
| Xu X et al. | Multifunctionalized 3-hydroxypyrroles in a three-step, one-pot cascade process from methyl 3-TBSO-2-diazo-3-butenoate and nitrones. | 2011 | Org. Lett. | pmid:22032199 |
| Huang XH et al. | Spiculoic acids A and B, new polyketides isolated from the Caribbean marine sponge Plakortis angulospiculatus. | 2004 | Org. Lett. | pmid:14703354 |
| El-Sheshtawy HS et al. | Solvent polarity affects H atom abstractions from C-H donors. | 2011 | Org. Lett. | pmid:21495712 |
| Beer LL and Moore BS | Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica. | 2007 | Org. Lett. | pmid:17274624 |
| Spangenberg T et al. | A new method for the synthesis of chiral beta-branched alpha-amino acids. | 2007 | Org. Lett. | pmid:17803310 |
| Takimoto T et al. | Effects of chemical inducers on the Epstein-Barr virus cycle in epithelial/nasopharyngeal carcinoma hybrid cell line. | 1984 | ORL J. Otorhinolaryngol. Relat. Spec. | pmid:6087237 |
| Dessein AF et al. | A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. | 2010 | Orphanet J Rare Dis | pmid:20923556 |
| Galanello R and Origa R | Beta-thalassemia. | 2010 | Orphanet J Rare Dis | pmid:20492708 |
| D'Amico A et al. | Spinal muscular atrophy. | 2011 | Orphanet J Rare Dis | pmid:22047105 |
| Provenzano MJ et al. | Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). | 2007 | Otolaryngol Head Neck Surg | pmid:17967635 |
| Takimoto T et al. | Effects of human interferon on cell proliferation and antigens induced by Epstein-Barr virus in epithelial hybrid cells derived from nasopharyngeal carcinoma. | 1985 | Otolaryngol Head Neck Surg | pmid:2995902 |
| Xu K et al. | Targeting HDACs: a promising therapy for Alzheimer's disease. | 2011 | Oxid Med Cell Longev | pmid:21941604 |
| Rahman M et al. | The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. | Oxid Med Cell Longev | pmid:20716918 | |
| Brodská B and Holoubek A | Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors. | 2011 | Oxid Med Cell Longev | pmid:21949898 |
| Amaeze OU et al. | Evaluation of antioxidant activity of Tetracarpidium conophorum (Müll. Arg) Hutch & Dalziel leaves. | 2011 | Oxid Med Cell Longev | pmid:21912723 |
| Crispo JA et al. | Role of reactive oxygen species in the neural and hormonal regulation of the PNMT gene in PC12 cells. | 2011 | Oxid Med Cell Longev | pmid:22007271 |
| Tarrerias AL et al. | Short-chain fatty acid enemas fail to decrease colonic hypersensitivity and inflammation in TNBS-induced colonic inflammation in rats. | 2002 | Pain | pmid:12435462 |
| Davis MP | Drug management of visceral pain: concepts from basic research. | 2012 | Pain Res Treat | pmid:22619712 |
| Salam S | Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. | 1988 | Pak J Pharm Sci | pmid:16414615 |
| Swarovsky B et al. | Sodium butyrate induces neuroendocrine cytodifferentiation in the insulinoma cell line RINm5F. | 1994 | Pancreas | pmid:7937695 |
| el-Deriny SE et al. | Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells. | 1987 | Pancreas | pmid:3575313 |
| Mullins TD et al. | Ultrastructural differentiation of sodium butyrate-treated human pancreatic adenocarcinoma cell lines. | 1991 | Pancreas | pmid:1946315 |
| Fernandez-Mejia C and Davidson MB | Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells. | 1993 | Pancreas | pmid:8302795 |
| Sileikiene V et al. | Effect of ileal infusion of short-chain fatty acids on pancreatic prandial secretion and gastrointestinal hormones in pigs. | 2008 | Pancreas | pmid:18665083 |
| Bloom EJ et al. | Effect of sodium butyrate, a differentiating agent, on cell surface glycoconjugates of a human pancreatic cell line. | 1989 | Pancreas | pmid:2717602 |
| Pellizzaro C et al. | Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-But, a hyaluronic butyric ester: a preliminary report. | 2008 | Pancreas | pmid:18437074 |
| Berrilli F et al. | Giardia duodenalis assemblages and Entamoeba species infecting non-human primates in an Italian zoological garden: zoonotic potential and management traits. | 2011 | Parasit Vectors | pmid:21988762 |
| Li JV et al. | Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. | 2011 | Parasit Vectors | pmid:21929782 |
| Aivazi AA and Vijayan VA | Larvicidal activity of oak Quercus infectoria Oliv. (Fagaceae) gall extracts against Anopheles stephensi Liston. | 2009 | Parasitol. Res. | pmid:19148681 |
| Moon HI | Antiplasmodial activity of ineupatorolides A from Carpesium rosulatum. | 2007 | Parasitol. Res. | pmid:17102985 |
| Nakamura CV and Pinto AS | Biological effects of lithium chloride on the insect trypanosomatid Herpetomonas samuelpessoai. | 1989 | Parasitology | pmid:2556681 |
| Munir WA and Barrett J | The metabolism of xenobiotic compounds by Hymenolepis diminuta (Cestoda: Cyclophyllidea). | 1985 | Parasitology | pmid:4034242 |
| Mizuno H et al. | α-Synuclein Transgenic Drosophila As a Model of Parkinson's Disease and Related Synucleinopathies. | 2010 | Parkinsons Dis | pmid:21209707 |
| Henry F et al. | Role of antigen-presenting cells in long-term antitumor response based on tumor-derived apoptotic body vaccination. | 1999 | Pathobiology | pmid:10725809 |
| Fotovati A et al. | N-myc downstream-regulated gene 1 (NDRG1) a differentiation marker of human breast cancer. | 2011 | Pathol. Oncol. Res. | pmid:21221878 |
| Zeckey C et al. | Synthetic (glyco-)peptides of the homophilic recognition domain of E-cadherin lead to increased E-cadherin mRNA synthesis and are inductors of cell differentiation in primary lung cancer cell lines. | 2010 | Pathol. Res. Pract. | pmid:20403671 |
| Aozasa K et al. | Malignant lymphoma in the nose. Clinicopathological differences from the malignant histiocytosis presenting as lethal midline granuloma. | 1981 | Pathol. Res. Pract. | pmid:7312704 |
| Rudnick DA et al. | Serum alpha-NH-butyric acid may predict spontaneous survival in pediatric acute liver failure. | 2009 | Pediatr Transplant | pmid:18643912 |
| Mally P et al. | Stereospecific regulation of tyrosine hydroxylase and proenkephalin genes by short-chain fatty acids in rat PC12 cells. | 2004 | Pediatr. Res. | pmid:14739357 |
| Nakajima T et al. | The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. | 1997 | Pediatr. Res. | pmid:9212045 |
| Weng M et al. | Butyrate regulates the expression of pathogen-triggered IL-8 in intestinal epithelia. | 2007 | Pediatr. Res. | pmid:17805211 |
| Peng L et al. | Effects of butyrate on intestinal barrier function in a Caco-2 cell monolayer model of intestinal barrier. | 2007 | Pediatr. Res. | pmid:17211138 |
| Saudubray JM et al. | Oxidation of fatty acids in cultured fibroblasts: a model system for the detection and study of defects in oxidation. | 1982 | Pediatr. Res. | pmid:7145511 |
| Jacobs HC et al. | Fetal lung mRNA levels of Hox genes are differentially altered by maternal diabetes and butyrate in rats. | 1998 | Pediatr. Res. | pmid:9667378 |
| Nankova BB et al. | Nicotinic induction of preproenkephalin and tyrosine hydroxylase gene expression in butyrate-differentiated rat PC12 cells: a model for adaptation to gut-derived environmental signals. | 2003 | Pediatr. Res. | pmid:12508089 |
| Nafday SM et al. | Short-chain fatty acids induce colonic mucosal injury in rats with various postnatal ages. | 2005 | Pediatr. Res. | pmid:15611351 |
| Dyer JP et al. | The effect of short-chain fatty acids butyrate, propionate, and acetate on urothelial cell kinetics in vitro: potential therapy in augmentation cystoplasty. | 2005 | Pediatr. Surg. Int. | pmid:15864601 |
| Uchida K et al. | Immunonutritional effects during synbiotics therapy in pediatric patients with short bowel syndrome. | 2007 | Pediatr. Surg. Int. | pmid:17205292 |
| Wittig R and Coy JF | The role of glucose metabolism and glucose-associated signalling in cancer. | 2008 | Perspect Medicin Chem | pmid:19812737 |
| Hernández-Ledesma B and de Lumen BO | Lunasin: a novel cancer preventive seed Peptide. | 2008 | Perspect Medicin Chem | pmid:19787099 |
| Tóth M et al. | Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. | 2003 | Pest Manag. Sci. | pmid:12701702 |
| Roy J et al. | Exposure to sodium butyrate leads to functional downregulation of calcium-activated potassium channels in human airway epithelial cells. | 2006 | Pflugers Arch. | pmid:17047984 |
| Lang F et al. | Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation. | 2000 | Pflugers Arch. | pmid:11041557 |
| Duquette RA and Wray S | pH regulation and buffering power in gastric smooth muscle. | 2001 | Pflugers Arch. | pmid:11484779 |
| Katoh K and Yajima T | Effects of butyric acid and analogues on amylase release from pancreatic segments of sheep and goats. | 1989 | Pflugers Arch. | pmid:2470024 |
| Vais H et al. | Novel adenoviral vectors coding for GFP-tagged wtCFTR and deltaF508-CFTR: characterization of expression and electrophysiological properties in A549 cells. | 2004 | Pflugers Arch. | pmid:15452712 |
| Austin C and Wray S | A quantitative study of the relation between intracellular pH and force in rat mesenteric vascular smooth muscle. | 1994 | Pflugers Arch. | pmid:8072846 |
| Taggart M and Wray S | Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. | 1993 | Pflugers Arch. | pmid:8351202 |
| Diener M et al. | Effect of short-chain fatty acids on cell volume and intracellular pH in rat distal colon. | 1993 | Pflugers Arch. | pmid:8414909 |
| Austin C and Wray S | An investigation of intrinsic buffering power in rat vascular smooth muscle cells. | 1995 | Pflugers Arch. | pmid:7761256 |
| Eisner DA et al. | A novel method for absolute calibration of intracellular pH indicators. | 1989 | Pflugers Arch. | pmid:2740208 |
| Taggart MJ et al. | Stimulus-dependent modulation of smooth muscle intracellular calcium and force by altered intracellular pH. | 1996 | Pflugers Arch. | pmid:8772130 |
| Yabuuchi H et al. | Possible role of anion exchanger AE2 as the intestinal monocarboxylic acid/anion antiporter. | 1998 | Pharm. Res. | pmid:9563070 |
| Diakidou A et al. | Characterization of the contents of ascending colon to which drugs are exposed after oral administration to healthy adults. | 2009 | Pharm. Res. | pmid:19572187 |
| Addicks WJ et al. | Validation of a flow-through diffusion cell for use in transdermal research. | 1987 | Pharm. Res. | pmid:3509887 |
| Anand P et al. | Cancer is a preventable disease that requires major lifestyle changes. | 2008 | Pharm. Res. | pmid:18626751 |
| Cummins CL et al. | Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. | 2001 | Pharm. Res. | pmid:11587480 |
| Kido Y et al. | Functional clarification of MCT1-mediated transport of monocarboxylic acids at the blood-brain barrier using in vitro cultured cells and in vivo BUI studies. | 2000 | Pharm. Res. | pmid:10714609 |
| Del Terzo S et al. | Iontophoretic transport of a homologous series of ionized and nonionized model compounds: influence of hydrophobicity and mechanistic interpretation. | 1989 | Pharm. Res. | pmid:2717524 |
| Chiao CS and Price JC | Modification of gelatin beadlets for zero-order sustained release. | 1989 | Pharm. Res. | pmid:2762229 |
| Morgen M et al. | Polymeric nanoparticles for increased oral bioavailability and rapid absorption using celecoxib as a model of a low-solubility, high-permeability drug. | 2012 | Pharm. Res. | pmid:21863477 |
| Tabolacci E et al. | Modest reactivation of the mutant FMR1 gene by valproic acid is accompanied by histone modifications but not DNA demethylation. | 2008 | Pharmacogenet. Genomics | pmid:18622267 |
| Makis AC et al. | The genomics of new drugs in sickle cell disease. | 2006 | Pharmacogenomics | pmid:16981849 |
| Kanai H et al. | Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons. | 2004 | Pharmacogenomics J. | pmid:15289798 |
| Samarghandian S et al. | Antihyperglycemic and antihyperlipidemic effects of guar gum on streptozotocin-induced diabetes in male rats. | 2012 | Pharmacogn Mag | pmid:22438666 |
| Hadjzadeh MA et al. | The preventive effect of N-butanol fraction of Nigella sativa on ethylene glycol-induced kidney calculi in rats. | 2011 | Pharmacogn Mag | pmid:22262938 |
| Chackrewarthy S et al. | Evaluation of the hypoglycemic and hypolipidemic effects of an ethylacetate fraction of Artocarpus heterophyllus (jak) leaves in streptozotocin-induced diabetic rats. | 2010 | Pharmacogn Mag | pmid:20931077 |
| Dugasani S et al. | Antimicrobial activity of Bauhinia tomentosa and Bauhinia vahlii roots. | 2010 | Pharmacogn Mag | pmid:20931080 |
| Adebayo AH et al. | Anticancer and antiradical scavenging activity of Ageratum conyzoides L. (Asteraceae). | 2010 | Pharmacogn Mag | pmid:20548938 |
| Gutierrez RM et al. | Attenuation of nonenzymatic glycation, hyperglycemia, and hyperlipidemia in streptozotocin-induced diabetic rats by chloroform leaf extract of Azadirachta indica. | 2011 | Pharmacogn Mag | pmid:21969798 |
| Perera PK and Li Y | Functional herbal food ingredients used in type 2 diabetes mellitus. | 2012 | Pharmacogn Rev | pmid:22654403 |
| Ali M and Chaudhary N | Ficus hispida Linn.: A review of its pharmacognostic and ethnomedicinal properties. | 2011 | Pharmacogn Rev | pmid:22096323 |
| Suganya S et al. | Amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb Euphorbia hirta. | 2011 | Pharmacognosy Res | pmid:22022170 |
| Balijepalli MK et al. | Antiproliferative activity and induction of apoptosis in estrogen receptor-positive and negative human breast carcinoma cell lines by Gmelina asiatica roots. | 2010 | Pharmacognosy Res | pmid:21808551 |
| Ceriani T et al. | Cyclic AMP mediator of gastric mucosa cytoprotection during fatty acids damaging. | 1981 | Pharmacol Res Commun | pmid:6270705 |
| Raybuck JD et al. | The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. | 2013 | Pharmacol. Biochem. Behav. | pmid:23454534 |
| Liu H et al. | Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion. | 2015 | Pharmacol. Biochem. Behav. | pmid:26013850 |
| Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |