| MeSH term | MeSH ID | Detail |
|---|---|---|
| Enterocolitis, Pseudomembranous | D004761 | 8 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Facial Injuries | D005151 | 1 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fragile X Syndrome | D005600 | 5 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glycogen Storage Disease Type II | D006009 | 2 associated lipids |
| Granuloma, Lethal Midline | D006103 | 2 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hemorrhoids | D006484 | 2 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| George CH et al. | Rapid determination of gap junction formation using HeLa cells microinjected with cDNAs encoding wild-type and chimeric connexins. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9647771 |
| Dangond F and Gullans SR | Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9647779 |
| Filippovich I et al. | Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of HSP70 mRNA. | 1994 | Biochem. Biophys. Res. Commun. | pmid:7904816 |
| Rivero JA and Adunyah SE | Sodium butyrate stimulates PKC activation and induces differential expression of certain PKC isoforms during erythroid differentiation. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9703983 |
| Kitzis A et al. | Effect of sodium butyrate on chromatin structure. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7387680 |
| Gaudier E et al. | Butyrate regulation of glycosylation-related gene expression: evidence for galectin-1 upregulation in human intestinal epithelial goblet cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15541394 |
| Tong X et al. | Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15063780 |
| Bai L and Merchant JL | ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17560543 |
| Daniel C et al. | p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15504345 |
| Nagelberg SB et al. | Pretranslational regulation of ectopic hCG alpha production in ChaGo lung cancer cells by sodium butyrate. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2417603 |
| Seki J et al. | Dimethyl sulfoxide and related polar compounds enhance infection of human T cells with HIV-1 in vitro. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8886001 |
| BektaÅŸoÄŸlu B et al. | Novel hydroxyl radical scavenging antioxidant activity assay for water-soluble antioxidants using a modified CUPRAC method. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16716257 |
| Reppe S et al. | Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15465005 |
| Bohan C et al. | Sodium butyrate activates human immunodeficiency virus long terminal repeat--directed expression. | 1987 | Biochem. Biophys. Res. Commun. | pmid:2825693 |
| Fishman PH et al. | Induction of glycolipid biosynthesis by sodium butyrate in HeLa cells. | 1974 | Biochem. Biophys. Res. Commun. | pmid:4858378 |
| Kinoshita M et al. | Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activation. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12054544 |
| Tabuchi Y et al. | Identification of genes responsive to sodium butyrate in colonic epithelial cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12054516 |
| Kitzis A et al. | Localization of phosphoproteins and of protein kinases in chromatin from butyrate treated HTC cells. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7470113 |
| Oster T et al. | Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8099285 |
| Kitajima M et al. | Characterization of baculovirus Autographa californica multiple nuclear polyhedrosis virus infection in mammalian cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16545777 |
| Steiner E et al. | SP-transcription factors are involved in basal MVP promoter activity and its stimulation by HDAC inhibitors. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15047174 |
| Weingarten D and de Vellis J | Selective inhibition by sodium butyrate of the glucocorticoid induction of glycerol phosphate dehydrogenase in glial cultures. | 1980 | Biochem. Biophys. Res. Commun. | pmid:6772178 |
| TaÅŸtan Bishop AO and Sewell T | A new approach to possible substrate binding mechanisms for nitrile hydratase. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16540090 |
| Akiba Y et al. | Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20170631 |
| Wiegandt H et al. | Retinoic acid alters the metabolic 3H-labelling of glycosphingolipids. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3032172 |
| Mori Y et al. | Differential effect of sodium butyrate on cyclic AMP phosphodiesterase activities in butyrate sensitive and resistant mastocytoma cells. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3019329 |
| Siavoshian S et al. | Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125124 |
| Ide Y et al. | Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16434023 |
| Ogawa H et al. | Butyrate modulates gene and protein expression in human intestinal endothelial cells. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12963019 |
| Abramova MV et al. | e2f1 Gene is a new member of Wnt/beta-catenin/Tcf-regulated genes. | 2010 | Biochem. Biophys. Res. Commun. | pmid:19900401 |
| McMillan L et al. | Bile acids reduce the apoptosis-inducing effects of sodium butyrate on human colon adenoma (AA/C1) cells: implications for colon carcinogenesis. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10873561 |
| Lee IH et al. | Involvement of CCAAT/enhancer-binding protein alpha in haptoglobin gene expression by all-trans-retinoic acid. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12074569 |
| Gaschott T et al. | Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11676498 |
| Ormandy CJ et al. | Coordinate regulation of oestrogen and prolactin receptor expression by sodium butyrate in human breast cancer cells. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1734881 |
| Radhakrishnan P et al. | Butyrate induces sLex synthesis by stimulation of selective glycosyltransferase genes. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17553459 |
| Staecker JL et al. | Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by sodium butyrate. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3632683 |
| Tang DC and Taylor MW | Memory of butyrate induction by the Moloney murine sarcoma virus enhancer-promoter element. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1449468 |
| Garbutt GJ and Abraham EC | Stimulation of minor fetal hemoglobin synthesis in cord blood reticulocytes by butyrate. | 1981 | Biochem. Biophys. Res. Commun. | pmid:6164369 |
| Leibovitch MP et al. | Effect of sodium butyrate on gene expression in a rat myogenic cell line. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6517941 |
| Wei P et al. | Reversible immortalization of Nestin-positive precursor cells from pancreas and differentiation into insulin-secreting cells. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22266322 |
| Wächtershäuser A et al. | Expression of 5-lipoxygenase by human colorectal carcinoma Caco-2 cells during butyrate-induced cell differentiation. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10679282 |
| Kaneko Y et al. | Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2843181 |
| Leibovitch MP and Kruh J | Effect of sodium butyrate on myoblast growth and differentiation. | 1979 | Biochem. Biophys. Res. Commun. | pmid:454435 |
| Hatayama H et al. | The short chain fatty acid, butyrate, stimulates MUC2 mucin production in the human colon cancer cell line, LS174T. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17374366 |
| Lee SK et al. | Cellular differentiation-induced attenuation of LPS response in HT-29 cells is related to the down-regulation of TLR4 expression. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16202385 |
| Qin S and Yamamura H | Up-regulation of Syk activity during HL60 cell differentiation into granulocyte but not into monocyte/macrophage-lineage. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9245716 |
| Adolf GR and Swetly P | Effects of butyrate on induction and action of interferon. | 1981 | Biochem. Biophys. Res. Commun. | pmid:6174120 |
| Bell PA and Jones CN | Cytotoxic effects of butyrate and other 'differentiation inducers' on immature lymphoid cells. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6176240 |
| Stevens MS et al. | Associated effects of sodium butyrate on histone acetylation and estrogen receptor in the human breast cancer cell line MCF-7. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6704117 |
| Hammill D et al. | The D-domain of Sp3 modulates its protein levels and activation of the p21(CIP1/WAF1) promoter. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16081043 |
| Russo GL et al. | Down-regulation of protein kinase CKII activity by sodium butyrate. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9168912 |
| Gaschott T et al. | 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11322770 |
| Aung CS et al. | Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17321497 |
| Laubach VE et al. | High-level expression of human inducible nitric oxide synthase in Chinese hamster ovary cells and characterization of the purified enzyme. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8579595 |
| Ho LH et al. | Involvement of intracellular labile zinc in suppression of DEVD-caspase activity in human neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10652229 |
| Prasad MR et al. | Kinetic evidence for two separate trans-2-enoyl CoA reductases in rat hepatic microsomes: NADPH-specific short chain- and NAD(P)H-dependent long chain-reductase. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6870879 |
| Belakavadi M et al. | Butyrate-induced proapoptotic and antiangiogenic pathways in EAT cells require activation of CAD and downregulation of VEGF. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16105646 |
| Mandal M et al. | Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403841 |
| Nilsson NE et al. | Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12684041 |
| Rabelo FL et al. | Apoptosis induced by butyrate is independent of Jak/STAT signaling in a fibrosarcoma cell line. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12589807 |
| Yan JK et al. | Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27888107 |
| Terakawa M et al. | Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15919053 |
| Souleimani A and Asselin C | Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8503924 |
| Bergann T et al. | A colonic mineralocorticoid receptor cell model expressing epithelial Na+ channels. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19275887 |
| Han L et al. | Histone acetyltransferase p300 regulates the transcription of human erythroid-specific 5-aminolevulinate synthase gene. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16904069 |
| Yano S and Tierney DF | Butyrate increases catalase activity and protects rat pulmonary artery smooth muscle cells against hyperoxia. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2590195 |
| Moore-Hoon ML and Turner RJ | Increased expression of the secretory Na+-K+-2Cl- cotransporter with differentiation of a human intestinal cell line. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9514875 |
| Coats SR et al. | Ligand-specific control of src-suppressed C kinase substrate gene expression. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12372401 |
| Nikolić N et al. | Overexpression of PGC-1α increases fatty acid oxidative capacity of human skeletal muscle cells. | 2012 | Biochem Res Int | pmid:21904680 |
| Iwalokun BA et al. | Evaluation of the Possible Mechanisms of Antihypertensive Activity of Loranthus micranthus: An African Mistletoe. | 2011 | Biochem Res Int | pmid:21918720 |
| Ichikawa N et al. | Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate. | 1984 | Biken J | pmid:6443174 |
| Fürll M et al. | [Hormonal reactions in fattening bulls and cows during a three-week butyric acid exposure]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267563 |
| Fürll M et al. | [Effect of a three-week butyric acid exposure on the mineral metabolism and the skeletal system in cattle]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267564 |
| Havenaar R | Intestinal health functions of colonic microbial metabolites: a review. | 2011 | Benef Microbes | pmid:21840809 |
| Roelofsen H et al. | The interaction of short-chain fatty acids with adipose tissue: relevance for prevention of type 2 diabetes. | 2010 | Benef Microbes | pmid:21831781 |
| Bird AR et al. | Resistant starch, large bowel fermentation and a broader perspective of prebiotics and probiotics. | 2010 | Benef Microbes | pmid:21831780 |
| Binsl TW et al. | Measuring non-steady-state metabolic fluxes in starch-converting faecal microbiota in vitro. | 2010 | Benef Microbes | pmid:21831778 |
| Mäkeläinen H et al. | Xylo-oligosaccharides enhance the growth of bifidobacteria and Bifidobacterium lactis in a simulated colon model. | 2010 | Benef Microbes | pmid:21831753 |
| Mäkivuokko H et al. | Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model. | 2010 | Benef Microbes | pmid:21840801 |
| Fernando WM et al. | Diets supplemented with chickpea or its main oligosaccharide component raffinose modify faecal microbial composition in healthy adults. | 2010 | Benef Microbes | pmid:21831757 |
| Zhu Y et al. | [In vitro study about the inhibitory effect of CDAII in combination with sodium butyrate on breast cancer cells]. | 2007 | Beijing Da Xue Xue Bao | pmid:17940563 |
| Wallace KJ and Rosen JB | Predator odor as an unconditioned fear stimulus in rats: elicitation of freezing by trimethylthiazoline, a component of fox feces. | 2000 | Behav. Neurosci. | pmid:11085605 |
| Lattal KM et al. | Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction. | 2007 | Behav. Neurosci. | pmid:17907845 |
| Petry FS et al. | Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. | 2016 | Behav. Brain Res. | pmid:27025446 |
| Horii Y et al. | Exposure to TMT odor affects adrenal sympathetic nerve activity and behavioral consequences in rats. | 2010 | Behav. Brain Res. | pmid:20595033 |
| Sharma S et al. | Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity. | 2015 | Behav. Brain Res. | pmid:26048426 |
| Yang J et al. | Inhibition of nuclear factor-κB impairs reconsolidation of morphine reward memory in rats. | 2011 | Behav. Brain Res. | pmid:20816896 |
| Ayers LW et al. | Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. | 2013 | Behav. Brain Res. | pmid:23831303 |
| Kalda A et al. | Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice. | 2007 | Behav. Brain Res. | pmid:17477979 |
| Reolon GK et al. | Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats. | 2011 | Behav. Brain Res. | pmid:21421011 |
| Zhu H et al. | Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors. | 2009 | Behav. Brain Res. | pmid:18817816 |
| Watanabe T et al. | Green odor and depressive-like state in rats: toward an evidence-based alternative medicine? | 2011 | Behav. Brain Res. | pmid:21684308 |
| Moretti M et al. | Behavioral and neurochemical effects of sodium butyrate in an animal model of mania. | 2011 | Behav Pharmacol | pmid:21989497 |
| Resende WR et al. | Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer. | 2013 | Behav Pharmacol | pmid:23994816 |
| Podzuweit T et al. | Cyclic AMP mediated arrhythmias induced in the ischaemic pig heart. | 1981 Jul-Aug | Basic Res. Cardiol. | pmid:6116488 |
| Ishihara K et al. | Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19486331 |
| Timbermont L et al. | Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. | 2010 | Avian Pathol. | pmid:20390546 |
| Van Deun K et al. | Short-chain fatty acids and L-lactate as feed additives to control Campylobacter jejuni infections in broilers. | 2008 | Avian Pathol. | pmid:18622853 |
| Ping W et al. | Baculovirus-mediated gene expression in chicken primary cells. | 2006 | Avian Dis. | pmid:16617983 |
| Henriksen M et al. | Evaluation of PCR and DNA sequencing for direct detection of Clostridium perfringens in the intestinal tract of broilers. | 2009 | Avian Dis. | pmid:19848086 |