| MeSH term | MeSH ID | Detail |
|---|---|---|
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Peritonitis | D010538 | 38 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Dentin, Secondary | D003809 | 2 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Medina V et al. | Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. | 1997 | Cancer Res. | pmid:9288776 |
| Talley NA et al. | Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial. | 1997 | Dis. Colon Rectum | pmid:9293933 |
| Ohno Y et al. | Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9294201 |
| Lewis SJ and Heaton KW | Increasing butyrate concentration in the distal colon by accelerating intestinal transit. | 1997 | Gut | pmid:9301506 |
| Chénais B et al. | Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels. | 1997 | Leukemia | pmid:9305615 |
| Cuisset L et al. | The effects of sodium butyrate on transcription are mediated through activation of a protein phosphatase. | 1997 | J. Biol. Chem. | pmid:9305863 |
| Birkett AM et al. | Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. | 1997 | Eur J Clin Nutr | pmid:9306090 |
| Ishiguro K and Sartorelli AC | Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin. | 1997 | Blood | pmid:9310478 |
| Hague A et al. | bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. | 1997 | Int. J. Cancer | pmid:9311611 |
| Dohi H et al. | Intake stimulants in perennial ryegrass (Lolium perenne L.) fed to sheep. | 1997 | J. Dairy Sci. | pmid:9313150 |
| Engelhard HH et al. | Molecular characterization of glioblastoma cell differentiation. | 1997 | Neurosurgery | pmid:9316051 |
| Scannell JP et al. | Antimetabolites produced by microorganisms. XIII. The synthesis and microbiological production of a novel amino acid, L-2-amino-4-(2-aminoethoxy) butanoic acid. | 1976 | J. Antibiot. | pmid:931793 |
| Kaiser E and Weiss K | [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. | 1997 | Arch Tierernahr | pmid:9324922 |
| Janson W et al. | Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis. | 1997 | Oncogene | pmid:9333015 |
| Sovová V et al. | Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines. | 1997 | Folia Biol. (Praha) | pmid:9338115 |
| Garcia-Bermejo L et al. | Modulation of heat-shock protein 70 (HSP70) gene expression by sodium butyrate in U-937 promonocytic cells: relationships with differentiation and apoptosis. | 1997 | Exp. Cell Res. | pmid:9344607 |
| Vecchia MG et al. | Acetate and propionate potentiate the antiproliferative effect of butyrate on RBL-2H3 growth. | 1997 | Gen. Pharmacol. | pmid:9347317 |
| Loukopoulos D | New therapies for the haemoglobinopathies. | 1997 | J Intern Med Suppl | pmid:9350181 |
| Kavaliers M et al. | Opioid and non-opioid NMDA-mediated predator-induced analgesia in mice and the effects of parasitic infection. | 1997 | Brain Res. | pmid:9359582 |
| O'Mara FP et al. | Rumen fermentation and nutrient flows for cows fed grass and grass supplemented with molassed beet pulp pellets. | 1997 | J. Dairy Sci. | pmid:9361218 |
| Barnard JA et al. | Short chain fatty acid regulation of intestinal gene expression. | 1997 | Adv. Exp. Med. Biol. | pmid:9361821 |
| Velázquez OC et al. | Butyrate and the colonocyte. Production, absorption, metabolism, and therapeutic implications. | 1997 | Adv. Exp. Med. Biol. | pmid:9361838 |
| Velázquez OC and Rombeau JL | Butyrate. Potential role in colon cancer prevention and treatment. | 1997 | Adv. Exp. Med. Biol. | pmid:9361842 |
| Singh M | Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro. | 1979 | J. Physiol. (Lond.) | pmid:93637 |
| Payne KL et al. | Modulation of T3-induced sex hormone-binding globulin secretion by human hepatoblastoma cells. | 1997 | Eur. J. Endocrinol. | pmid:9368511 |
| Velázquez OC et al. | Butyrate inhibits deoxycholate-induced increase in colonic mucosal DNA and protein synthesis in vivo. | 1997 | Dis. Colon Rectum | pmid:9369115 |
| Kolesnitchenko V et al. | A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis. | 1997 | J. Virol. | pmid:9371641 |
| Faller DV and Perrine SP | Butyrate in the treatment of sickle cell disease and beta-thalassemia. | 1995 | Curr. Opin. Hematol. | pmid:9371980 |
| Coradini D et al. | Effect of sodium butyrate on human breast cancer cell lines. | 1997 Mar-Apr | Cell Prolif. | pmid:9375027 |
| Onaga T et al. | Effect of pituitary adenylate cyclase-activating polypeptide on exocrine and endocrine secretion in the ovine pancreas. | 1996 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9375356 |
| Hassig CA et al. | Fiber-derived butyrate and the prevention of colon cancer. | 1997 | Chem. Biol. | pmid:9384528 |
| Vimard C et al. | Changes in the sedimentation properties of acetycholinesterase during neuroblastoma differentiation. | 1976 | Biochimie | pmid:938691 |
| Palmer DG et al. | Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. | 1997 | Int. J. Cancer | pmid:9398049 |
| Cordel S et al. | 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. | 1997 | Int. J. Cancer | pmid:9399677 |
| Moore JW et al. | Thiolmethyltransferase activity in the human colonic mucosa: implications for ulcerative colitis. | 1997 | J. Gastroenterol. Hepatol. | pmid:9407333 |
| Böhmig GA et al. | n-butyrate downregulates the stimulatory function of peripheral blood-derived antigen-presenting cells: a potential mechanism for modulating T-cell responses by short-chain fatty acids. | 1997 | Immunology | pmid:9415032 |
| Callus BA et al. | Haemoglobin synthesis in erythropoietin-stimulated J2E cells does not require increased numbers of transferrin receptors. | 1997 | Eur. J. Biochem. | pmid:9428699 |
| Yabushita H et al. | Emergence of an irreversible differentiated subclone from the poorly differentiated ovarian adenocarcinoma cell line AMOC-2 treated with sodium butyrate. | 1997 | J. Obstet. Gynaecol. Res. | pmid:9433040 |
| Ono M et al. | Resin glycosides. XXV. Multifidins I and II, new jalapins, from the seed of Quamoclit x multifida. | 1997 | Chem. Pharm. Bull. | pmid:9433765 |
| Medina V et al. | Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer. | 1998 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:9437648 |
| Gupta KP and Mehrotra NK | Differential effects of butyric acid on mouse skin tumorigenesis. | 1997 | Biomed. Environ. Sci. | pmid:9448925 |
| Perez-Esteban J et al. | Lipase activity of Pseudomonas fluorescens in cold raw skim milk with different lipid supplements. | 1997 | Folia Microbiol. (Praha) | pmid:9449781 |
| Leber BF and Denburg JA | Retinoic acid modulation of induced basophil differentiation. | 1997 | Allergy | pmid:9450139 |
| Saleh AW and Hillen HF | Pharmacological induction of foetal haemoglobin synthesis in sickle-cell disease. | 1997 | Neth J Med | pmid:9455096 |
| Llorente A et al. | Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus. | 1998 | J. Cell Biol. | pmid:9456316 |
| Gillenwater A et al. | Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate. | 1998 | Int. J. Cancer | pmid:9462711 |
| Shimizu A et al. | CyclinG contributes to G2/M arrest of cells in response to DNA damage. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9464250 |
| Yamane M et al. | Docosahexaenoic/arachidonic acid omega-hydroxylation system and differentiation in the human colonic adenocarcinoma cell line, Caco-2. | 1998 | Cancer Lett. | pmid:9464491 |
| Yamamoto I et al. | Interleukin-2-dependent augmentation of the anti-TNP antibody production by sodium butyrate in cultured murine splenic B cells. | 1997 | Int. J. Immunopharmacol. | pmid:9467754 |
| Dong-Le Bourhis X et al. | Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells. | 1998 | Br. J. Cancer | pmid:9472634 |