butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gruchlik A et al. | Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. | Acta Pol Pharm | pmid:21229889 | |
Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
González-Pajuelo M et al. | Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. | Metab. Eng. | pmid:16095939 | |
Ohata A et al. | Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation. | Nutrition | pmid:15975492 | |
Roy MJ et al. | In vitro studies on the inhibition of colon cancer by butyrate and carnitine. | Nutrition | pmid:19619983 | |
Vester BM et al. | Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). | Zoo Biol. | pmid:20095004 | |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Wang Y et al. | Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. | Ultrastruct Pathol | pmid:27158913 | |
Kim J et al. | Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. | Anticancer Res. | pmid:17970072 | |
Becker N et al. | Human intestinal microbiota: characterization of a simplified and stable gnotobiotic rat model. | Gut Microbes | pmid:21637015 | |
NofrarÃas M et al. | Long-term intake of resistant starch improves colonic mucosal integrity and reduces gut apoptosis and blood immune cells. | Nutrition | pmid:17936196 | |
Soto-Cruz O et al. | Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. | Biotechnol. Prog. | pmid:11934285 | |
Cai L et al. | Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. | J. Environ. Qual. | pmid:17215226 | |
Mangian HF and Tappenden KA | Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. | JPEN J Parenter Enteral Nutr | pmid:19892901 | |
Kodama N et al. | Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. | Cell Biochem. Funct. | pmid:15027099 | |
Fontanellas A et al. | Hemoglobin content is increased in the human erythroleukemia K562 cell line by a 56.2-kD peptide from uremic plasma. | Am. J. Nephrol. | pmid:15024177 | |
pmid:16166714 | ||||
Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
Singh NP and Lai HC | Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. | Anticancer Res. | pmid:16309236 | |
Lea MA et al. | Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. | Anticancer Res. | pmid:17465197 | |
Kien CL et al. | Lactulose feeding lowers cecal densities of clostridia in piglets. | JPEN J Parenter Enteral Nutr | pmid:17463144 | |
Sung YH et al. | Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. | Metab. Eng. | pmid:16169764 | |
Orchel A et al. | Influence of sodium butyrate on antioxidative enzymes activity in Caco-2 cell lines. | Acta Pol Pharm | pmid:17357609 | |
Noble R et al. | Olfactory response to mushroom composting emissions as a function of chemical concentration. | J. Environ. Qual. | pmid:11401265 | |
Hossain Z et al. | Growth inhibition and induction of differentiation and apoptosis mediated by sodium butyrate in Caco-2 cells with algal glycolipids. | In Vitro Cell. Dev. Biol. Anim. | pmid:16153148 | |
Drozdowski LA et al. | Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. | JPEN J Parenter Enteral Nutr | pmid:12005453 | |
Lokshina LY et al. | Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. | Appl. Biochem. Biotechnol. | pmid:12794281 | |
Loughrin JH et al. | Evaluation of second-generation multistage wastewater treatment system for the removal of malodors from liquid swine waste. | J. Environ. Qual. | pmid:19549951 | |
Wei ZL et al. | Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. | Anticancer Res. | pmid:18630528 | |
Oh HK et al. | Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a. | Biotechnol. Prog. | pmid:16080696 | |
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Rossi DL et al. | A new mammalian host cell with enhanced survival enables completely serum-free development of high-level protein production cell lines. | Biotechnol. Prog. | pmid:21473000 | |
Cai G et al. | Metabolic flux network and analysis of fermentative hydrogen production. | Biotechnol. Adv. | pmid:21362466 | |
Gassull MA et al. | Macronutrients and bioactive molecules: is there a specific role in the management of inflammatory bowel disease? | JPEN J Parenter Enteral Nutr | pmid:15980281 | |
Taylor AJ and Beck CW | Histone deacetylases are required for amphibian tail and limb regeneration but not development. | Mech. Dev. | pmid:22947425 | |
Wang B et al. | Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:18522857 | |
Scharlau D et al. | Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. | Mutat. Res. | pmid:19383551 | |
Ghosh SK et al. | Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. | Blood Cells Mol. Dis. | pmid:17161633 | |
Wang Q et al. | Characterization of monocarboxylate transport in human kidney HK-2 cells. | Mol. Pharm. | pmid:17140255 | |
Lim SJ et al. | Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. | Mol Med Rep | pmid:21475856 | |
Gennari L et al. | Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. | Phytochem Anal | pmid:21337646 | |
Cenkvári E et al. | Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. | J Anim Physiol Anim Nutr (Berl) | pmid:15787990 | |
Liu L et al. | Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:22698927 | |
Joachimiak R et al. | Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. | Acta Pol Pharm | pmid:18323252 | |
Fathallah H et al. | Differences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease. | Blood Cells Mol. Dis. | pmid:19346141 | |
Grebenová D et al. | The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells. | Blood Cells Mol. Dis. | pmid:16978890 | |
Munn AJ et al. | Hindgut plasticity in wallabies fed hay either unchopped or ground and pelleted: fiber is not the only factor. | Physiol. Biochem. Zool. | pmid:19331583 | |
Bartholome AL et al. | Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. | JPEN J Parenter Enteral Nutr | pmid:15291402 | |
pmid:11071567 | ||||
Bijaya G et al. | Synthesis and evaluation of esmolol prodrugs for transdermal delivery. | Drug Deliv | pmid:20553111 |