butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Velázquez OC et al. | In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-Fos and c-Jun expression. | 1996 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:8865104 |
Tiedge M and Lenzen S | Effects of sodium butyrate on glucose transporter and glucose-phosphorylating enzyme gene expression in RINm5F insulinoma cells. | 1996 | J. Mol. Endocrinol. | pmid:8863183 |
Harig JM et al. | Transport of n-butyrate into human colonic luminal membrane vesicles. | 1996 | Am. J. Physiol. | pmid:8843764 |
Whitelaw E and Williamson DH | Effects of lactation of ketogenesis from oleate or butyrate in rat hepatocytes. | 1977 | Biochem. J. | pmid:883950 |
Mandal M and Kumar R | Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. | 1996 | Cell Growth Differ. | pmid:8838861 |
Recht LD et al. | Immunotoxin sensitivity of Chinese hamster ovary cells expressing human transferrin receptors with differing internalization rates. | 1996 | Cancer Immunol. Immunother. | pmid:8830739 |
Yamamoto I et al. | Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate. | 1996 | J. Biochem. | pmid:8827437 |
Vaziri C et al. | Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. | 1996 | J. Biol. Chem. | pmid:8824226 |
Fukamauchi F et al. | Differential effects of butyrate and dibutyryl cAMP on mRNA levels of muscarinic acetylcholine receptor subtypes expressed in neurohybrid cell lines. | 1996 | Neurosci. Lett. | pmid:8823760 |
Peldszus S et al. | Determination of short-chain aliphatic, oxo- and hydroxy-acids in drinking water at low microgram per liter concentrations. | 1996 | J Chromatogr A | pmid:8819819 |
Horiuchi A and Felder RA | High-level expression of rat D1A dopamine receptor cDNA in mouse fibroblast LTK- cells by n-butyrate. | 1996 | Clin. Exp. Pharmacol. Physiol. | pmid:8819644 |
Kendall PE and McLeay LM | Excitatory effects of volatile fatty acids on the in vitro motility of the rumen of sheep. | 1996 | Res. Vet. Sci. | pmid:8819185 |
Lindner H et al. | Separation of acetylated core histones by hydrophilic-interaction liquid chromatography. | 1996 | J Chromatogr A | pmid:8817877 |
Wasserman LM et al. | cAMP effects on myogenic gene expression in rhabdomyosarcoma cells. | 1996 | Exp. Cell Res. | pmid:8806451 |
Chireux M et al. | Histone hyperacetylating agents stimulate promoter activity of human choline acetyltransferase gene in transfection experiment. | 1996 | Brain Res. Mol. Brain Res. | pmid:8804715 |
Welters CF et al. | Supplementation of enteral nutrition with butyrate leads to increased portal efflux of amino acids in growing pigs with short bowel syndrome. | 1996 | J. Pediatr. Surg. | pmid:8801305 |
Kopf MA et al. | Key role of alkanoic acids on the spectral properties, activity, and active-site stability of iron-containing nitrile hydratase from Brevibacterium R312. | 1996 | Eur. J. Biochem. | pmid:8797859 |
Keane MM et al. | The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells. | 1996 | Cancer Res. | pmid:8797598 |
Miettinen H and Huhtanen P | Effects of the ratio of ruminal propionate to butyrate on milk yield and blood metabolites in dairy cows. | 1996 | J. Dairy Sci. | pmid:8792285 |
Aaronson PI et al. | Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery. | 1996 | Br. J. Pharmacol. | pmid:8789392 |
Rottleb C et al. | Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression. | 1996 | Int. J. Cancer | pmid:8782665 |
McBain JA et al. | Phorbol ester augments butyrate-induced apoptosis of colon cancer cells. | 1996 | Int. J. Cancer | pmid:8782664 |
Feng P et al. | Sodium butyrate is a potent modulator of smooth muscle cell proliferation and gene expression. | 1996 | Cell Prolif. | pmid:8782486 |
Taggart MJ et al. | Stimulus-dependent modulation of smooth muscle intracellular calcium and force by altered intracellular pH. | 1996 | Pflugers Arch. | pmid:8772130 |
Dagher PC et al. | Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH. | 1996 | Am. J. Physiol. | pmid:8764164 |
Ghosh NK and Cox RP | Induction of human follicle-stimulating hormone in HeLa cells by sodium butyrate. | 1977 | Nature | pmid:876359 |
Goto I et al. | Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. | 1996 | Br. J. Cancer | pmid:8761368 |
Acheson DW et al. | Translocation of Shiga toxin across polarized intestinal cells in tissue culture. | 1996 | Infect. Immun. | pmid:8757867 |
Ogryzko VV et al. | Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. | 1996 | Mol. Cell. Biol. | pmid:8756678 |
Velázquez OC et al. | Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice. | 1996 | Surgery | pmid:8751616 |
Cheng G et al. | [Isolation and reassociation of acetogen and methanogen in a syntrophobic coculture degrading butyrate anaerobically]. | 1995 | Wei Sheng Wu Xue Bao | pmid:8745550 |
Diener M et al. | Neuronally mediated anion secretion induced by short-chain fatty acids in the rat distal small intestine. | 1996 | Acta Physiol. Scand. | pmid:8735652 |
Hodin RA et al. | Cellular growth state differentially regulates enterocyte gene expression in butyrate-treated HT-29 cells. | 1996 | Cell Growth Differ. | pmid:8732674 |
Madesh M et al. | Butyrate-induced alteration in lipid composition of human colon cell line HT-29. | 1996 | Biochem. Mol. Biol. Int. | pmid:8728094 |
Adams FS et al. | Characterization and transplantation of two neuronal cell lines with dopaminergic properties. | 1996 | Neurochem. Res. | pmid:8726972 |
Eftimiadi C et al. | Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. | 1995 | Minerva Stomatol | pmid:8721203 |
Olivieri NF | Reactivation of fetal hemoglobin in patients with beta-thalassemia. | 1996 | Semin. Hematol. | pmid:8714583 |
Rivero JA and Adunyah SE | Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8713125 |
Sharma JP et al. | Reversed-phase high-performance liquid chromatographic determination of tetracyclines in urine and plasma. | 1977 | J. Chromatogr. | pmid:870510 |
Rafferty SP et al. | Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line. | 1996 | Blood | pmid:8704216 |
Park C et al. | Differential expression and butyrate response of human alkaline phosphatase genes are mediated by upstream DNA elements. | 1996 | Biochemistry | pmid:8703954 |
Whiteley LO et al. | Evaluation in rats of the dose-response relationship among colonic mucosal growth, colonic fermentation, and dietary fiber. | 1996 | Dig. Dis. Sci. | pmid:8689925 |
Stein J et al. | Induction of glutathione-S-transferase-pi by short-chain fatty acids in the intestinal cell line Caco-2. | 1996 | Eur. J. Clin. Invest. | pmid:8682162 |
Velázquez OC et al. | Butyrate and the colonocyte. Implications for neoplasia. | 1996 | Dig. Dis. Sci. | pmid:8674394 |
McIntosh GH et al. | A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats. | 1996 | J. Gastroenterol. Hepatol. | pmid:8672754 |
Wiechmann AF | Recoverin in cultured human retinoblastoma cells: enhanced expression during morphological differentiation. | 1996 | J. Neurochem. | pmid:8666979 |
Smith TJ et al. | n-Butyrate induces plasminogen activator inhibitor type 1 messenger RNA in cultured Hep G2 cells. | 1996 | Hepatology | pmid:8666343 |
Vettese-Dadey M et al. | Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. | 1996 | EMBO J. | pmid:8665858 |
Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
Lin MC et al. | Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor. | 1979 | J. Biol. Chem. | pmid:86543 |