butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Etschmann B et al. | A vH+-ATPase is present in cultured sheep ruminal epithelial cells. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16825706 |
| Kiela PR et al. | Regulation of the rat NHE3 gene promoter by sodium butyrate. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11557515 |
| Jørgensen J and Mortensen PB | Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11447021 |
| Aschenbach JR et al. | Bicarbonate-dependent and bicarbonate-independent mechanisms contribute to nondiffusive uptake of acetate in the ruminal epithelium of sheep. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19264953 |
| Suply E et al. | Butyrate enemas enhance both cholinergic and nitrergic phenotype of myenteric neurons and neuromuscular transmission in newborn rat colon. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22492692 |
| Ogawa H et al. | Regulated production of the chemokine CCL28 in human colon epithelium. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15246961 |
| Tyagi S et al. | Mechanism of n-butyrate uptake in the human proximal colonic basolateral membranes. | 2002 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11897627 |
| Ramasamy S et al. | Sulfide-detoxifying enzymes in the human colon are decreased in cancer and upregulated in differentiation. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16500920 |
| Subramanya SB et al. | Differential regulation of cholera toxin-inhibited Na-H exchange isoforms by butyrate in rat ileum. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17690171 |
| Fukushima K and Fiocchi C | Paradoxical decrease of mitochondrial DNA deletions in epithelial cells of active ulcerative colitis patients. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15068964 |
| Cremin JD et al. | Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637251 |
| Amin MR et al. | Involvement of Sp1 and Sp3 in differential regulation of human NHE3 promoter activity by sodium butyrate and IFN-gamma/TNF-alpha. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17540780 |
| Xu H et al. | Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26159698 |
| Parhar K et al. | Short-chain fatty acid mediated phosphorylation of heat shock protein 25: effects on camptothecin-induced apoptosis. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16469826 |
| Archer SY et al. | The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16160080 |
| Borthakur A et al. | Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 level. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16150873 |
| Srinivas SR et al. | Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17855766 |
| Wu JT et al. | Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11171632 |
| Venkatraman A et al. | Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637250 |
| Grider JR and Piland BE | The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16973914 |
| Schweigel M and Martens H | Anion-dependent Mg2+ influx and a role for a vacuolar H+-ATPase in sheep ruminal epithelial cells. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12606303 |
| Vidyasagar S et al. | Role of short-chain fatty acids in colonic HCO(3) secretion. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15677553 |
| Vinolo MA et al. | Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22621868 |
| Silva P et al. | Competition between sodium reabsorption and gluconeogenesis in kidneys of steroid-treated rats. | 1980 | Am. J. Physiol. | pmid:7377301 |
| Chacin J et al. | Role of oxalacetate in lipoate effect on frog gastric mucosa. | 1976 | Am. J. Physiol. | pmid:8990 |
| Kenyon E et al. | Apical and basolateral membrane mechanisms that regulate pHi in bovine retinal pigment epithelium. | 1997 | Am. J. Physiol. | pmid:9277343 |
| Nutting CW et al. | Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. | 1991 | Am. J. Physiol. | pmid:1877681 |
| Jentsch TJ et al. | Electrical properties of sodium bicarbonate symport in kidney epithelial cells (BSC-1). | 1986 | Am. J. Physiol. | pmid:3024506 |
| Mannon PJ et al. | Characterization of a Y1-preferring NPY/PYY receptor in HT-29 cells. | 1994 | Am. J. Physiol. | pmid:7977753 |
| Cairns SP and Dulhunty AF | Beta-adrenoceptor activation shows high-frequency fatigue in skeletal muscle fibers of the rat. | 1994 | Am. J. Physiol. | pmid:8203484 |
| Lewandowski ED et al. | NMR studies of beta-oxidation and short-chain fatty acid metabolism during recovery of reperfused hearts. | 1991 | Am. J. Physiol. | pmid:1877663 |
| Bourne GA and Baldwin DM | Evidence for cAMP as a mediator of gonadotropin secretion from female pituitaries. | 1987 | Am. J. Physiol. | pmid:2820237 |
| Charney AN et al. | Nonionic diffusion of short-chain fatty acids across rat colon. | 1998 | Am. J. Physiol. | pmid:9530153 |
| Stanton RC et al. | Use of monoclonal antibodies to culture rat proximal tubule cells. | 1986 | Am. J. Physiol. | pmid:3022594 |
| Ardaillou N et al. | Vasoconstrictor-evoked prostaglandin synthesis in cultured human mesangial cells. | 1985 | Am. J. Physiol. | pmid:3918460 |
| Tarloff JB and Brand PH | Active tetraethylammonium uptake across the basolateral membrane of rabbit proximal tubule. | 1986 | Am. J. Physiol. | pmid:3728682 |
| Albina JE and Mastrofrancesco B | Modulation of glucose metabolism in macrophages by products of nitric oxide synthase. | 1993 | Am. J. Physiol. | pmid:7687412 |
| Natke E | Cell volume regulation of rabbit cortical collecting tubule in anisotonic media. | 1990 | Am. J. Physiol. | pmid:2360659 |
| Dobson A et al. | Absorption and exchange of water across rumen epithelium. | 1976 | Am. J. Physiol. | pmid:998805 |
| O'Donnell ME and Horwitz BA | Effects of butyrate on ouabain-sensitive respiration of hamster brown adipocytes. | 1982 | Am. J. Physiol. | pmid:7058878 |
| Hollander D and Rim E | Effect of luminal constituents on vitamin K1 absorption into thoracic duct lymph. | 1978 | Am. J. Physiol. | pmid:623249 |
| Dagher PC et al. | Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH. | 1996 | Am. J. Physiol. | pmid:8764164 |
| Snow TR and Caspar T | Substrate dependence of myocardial response to hypoxia in the presence of theophylline. | 1983 | Am. J. Physiol. | pmid:6881369 |
| Mariadason JM et al. | Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. | 1997 | Am. J. Physiol. | pmid:9142899 |
| Subero O et al. | Ca2+ requirement for metabolic effects of secretagogues in the amphibian gastric mucosa. | 1989 | Am. J. Physiol. | pmid:2514602 |
| Chander A | Regulation of lung surfactant secretion by intracellular pH. | 1989 | Am. J. Physiol. | pmid:2514603 |
| Keller SK et al. | Interactions of pH and K+ conductance in cultured bovine retinal pigment epithelial cells. | 1986 | Am. J. Physiol. | pmid:3942203 |
| Rome L et al. | Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. | 1989 | Am. J. Physiol. | pmid:2610250 |
| Hollander D et al. | Transport of butyric acid in vascularly perfused anuran small intestine: importance of pH and anion transport. | 1986 | Am. J. Physiol. | pmid:3485924 |
| Fitz JG et al. | Effect of pH on membrane potential and K+ conductance in cultured rat hepatocytes. | 1989 | Am. J. Physiol. | pmid:2558580 |