butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Carman RJ and Woodburn MA | Effects of low levels of ciprofloxacin on a chemostat model of the human colonic microflora. | 2001 | Regul. Toxicol. Pharmacol. | pmid:11407931 |
Méhul B et al. | Calmodulin-like skin protein: a new marker of keratinocyte differentiation. | 2001 | J. Invest. Dermatol. | pmid:11407979 |
Rubin VN et al. | Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics. | 2001 | Bioorg. Med. Chem. | pmid:11408177 |
Wächtershäuser A et al. | HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. | 2001 | Carcinogenesis | pmid:11408350 |
Rosato RR et al. | Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937). | 2001 | Int. J. Oncol. | pmid:11408941 |
Long JP and Hughes JH | Epstein-Barr virus latently infected cells are selectively deleted in simulated-microgravity cultures. | 2001 | In Vitro Cell. Dev. Biol. Anim. | pmid:11409687 |
Karagül-Yüceer Y et al. | Aroma-active components of nonfat dry milk. | 2001 | J. Agric. Food Chem. | pmid:11409991 |
Matthies C et al. | Clostridium uliginosum sp. nov., a novel acid-tolerant, anaerobic bacterium with connecting filaments. | 2001 | Int. J. Syst. Evol. Microbiol. | pmid:11411680 |
Etchebehere C et al. | Comamonas nitrativorans sp. nov., a novel denitrifier isolated from a denitrifying reactor treating landfill leachate. | 2001 | Int. J. Syst. Evol. Microbiol. | pmid:11411724 |
Nash MS et al. | Enhanced inducible mGlu1alpha receptor expression in Chinese hamster ovary cells. | 2001 | J. Neurochem. | pmid:11413250 |
Vessey DA and Kelley M | Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligase. | 2001 | Biochem. J. | pmid:11415461 |
Hsi LC et al. | Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells. | 2001 Apr-May | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11418015 |
Della Ragione F et al. | Genes modulated by histone acetylation as new effectors of butyrate activity. | 2001 | FEBS Lett. | pmid:11423116 |
Mahyar-Roemer M and Roemer K | p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. | 2001 | Oncogene | pmid:11423989 |
Topping DL and Clifton PM | Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. | 2001 | Physiol. Rev. | pmid:11427691 |
Borel C et al. | Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression. | 2001 | Hepatology | pmid:11431748 |
Takahashi N and Sato T | Preferential utilization of dipeptides by Porphyromonas gingivalis. | 2001 | J. Dent. Res. | pmid:11437213 |
Kanai M et al. | TGF-alpha inhibits apoptosis of murine gastric pit cells through an NF-kappaB-dependent pathway. | 2001 | Gastroenterology | pmid:11438494 |
Chaves N et al. | Identification and effects of interaction phytotoxic compounds from exudate of Cistus ladanifer leaves. | 2001 | J. Chem. Ecol. | pmid:11441449 |
Dyer KD and Rosenberg HF | Transcriptional regulation of galectin-10 (eosinophil Charcot-Leyden crystal protein): a GC box (-44 to -50) controls butyric acid induction of gene expression. | 2001 | Life Sci. | pmid:11441910 |
Jørgensen J and Mortensen PB | Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11447021 |
Guzev VS et al. | [Effect of butyric acid on physiologic activity of carbohydrate-oxidizing rhodococci]. | 2001 May-Jun | Mikrobiologiia | pmid:11450452 |
Marianna P et al. | Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. | 2001 | Haematologica | pmid:11454524 |
Herrmann AP et al. | Degradation of natural polyphenols by methanogenic consortia enriched from digested municipal sludge. | 2001 | Water Res. | pmid:11456154 |
Shearer J et al. | Why is there an "inert" metal center in the active site of nitrile hydratase? Reactivity and ligand dissociation from a five-coordinate Co(III) nitrile hydratase model. | 2001 | J. Am. Chem. Soc. | pmid:11456548 |
Marilley D et al. | Calretinin and calretinin-22k increase resistance toward sodium butyrate-induced differentiation in CaCo-2 colon adenocarcinoma cells. | 2001 | Exp. Cell Res. | pmid:11461122 |
Zheng T et al. | Agricultural exposure to carbamate pesticides and risk of non-Hodgkin lymphoma. | 2001 | J. Occup. Environ. Med. | pmid:11464396 |
Besong S et al. | Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet. | 2001 | J. Dairy Sci. | pmid:11467818 |
Hull CD and Cribb BW | Olfaction in the Queensland fruit fly, Bactrocera tryoni. I: Identification of olfactory receptor neuron types responding to environmental odors. | 2001 | J. Chem. Ecol. | pmid:11471941 |
Pouteau E et al. | Acetate, propionate and butyrate in plasma: determination of the concentration and isotopic enrichment by gas chromatography/mass spectrometry with positive chemical ionization. | 2001 | J Mass Spectrom | pmid:11473403 |
Derjuga A et al. | Expression of p21Waf1/Cip1 and cyclin D1 is increased in butyrate-resistant HeLa cells. | 2001 | J. Biol. Chem. | pmid:11477082 |
Iacomino G et al. | Transcriptional response of a human colon adenocarcinoma cell line to sodium butyrate. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11478796 |
Williamson DH and Ellington EV | Hydroxypyruvate as a gluconeogenic substrate in rat hepatocytes. | 1975 | Biochem. J. | pmid:1147901 |
Duquette RA and Wray S | pH regulation and buffering power in gastric smooth muscle. | 2001 | Pflugers Arch. | pmid:11484779 |
Clarke KO et al. | Tributyrin, an oral butyrate analogue, induces apoptosis through the activation of caspase-3. | 2001 | Cancer Lett. | pmid:11485828 |
Hernandez A et al. | Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis. | 2001 | Surgery | pmid:11490359 |
Kleessen B et al. | Oligofructose and long-chain inulin: influence on the gut microbial ecology of rats associated with a human faecal flora. | 2001 | Br. J. Nutr. | pmid:11502244 |
Nakhoul NL et al. | Ammonium interaction with the epithelial sodium channel. | 2001 | Am. J. Physiol. Renal Physiol. | pmid:11502598 |
Huang P et al. | [Inhibition of the expression of Epstein-Barr virus antigens in vitro by Chinese medicine compound "Dongxia wan"]. | 2000 | Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi | pmid:11503041 |
Ito N et al. | Inhibitory effects of sodium butyrate on proliferation and invasiveness of human glioma cells. | 2001 | Neurosurgery | pmid:11504120 |
Jørgensen J and Mortensen PB | Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis. | 2001 | Dig. Dis. Sci. | pmid:11508674 |
Shankaranarayanan P et al. | Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene. | 2001 | J. Biol. Chem. | pmid:11509556 |
Walker GE et al. | Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. | 2001 | Endocrinology | pmid:11517158 |
Sherfi SA and Hamad SH | Microbiological and biochemical studies on Gergoush fermentation. | 2001 | Int. J. Food Microbiol. | pmid:11518434 |
Chattopadhyay S et al. | Purification and stabilization of 99mTc-d,l-HMPAO: role of organic extractants. | 2001 | Nucl. Med. Biol. | pmid:11518658 |
Kasuga T | Effect of glutamate analogues on red-green opponent interaction in monkey electroretinograms. | 2001 | Exp. Eye Res. | pmid:11520106 |
Witt O et al. | Tumor cell differentiation by butyrate and environmental stress. | 2001 | Cancer Lett. | pmid:11520601 |
Finzer P et al. | Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression. | 2001 | Oncogene | pmid:11521189 |
Ugazio E et al. | The effect of formulation and concentration of cholesteryl butyrate solid lipid nanospheres (SLN) on NIH-H460 cell proliferation. | 2001 | Eur J Pharm Biopharm | pmid:11522486 |
Reinhardt D et al. | Post-transcriptional effects of interleukin-3, interferon-gamma, erythropoietin and butyrate on in vitro hemoglobin chain synthesis in congenital hemolytic anemia. | 2001 | Haematologica | pmid:11522534 |