butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kitazono M et al. | Enhanced adenovirus transgene expression in malignant cells treated with the histone deacetylase inhibitor FR901228. | 2001 | Cancer Res. | pmid:11522619 |
Ren H et al. | Short-chain fatty acids induce intestinal epithelial heat shock protein 25 expression in rats and IEC 18 cells. | 2001 | Gastroenterology | pmid:11522747 |
Benjamin D and Jost JP | Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. | 2001 | Nucleic Acids Res. | pmid:11522830 |
Stehle HW et al. | Short-chain carboxylic acids produced by gram-negative anaerobic bacteria can accelerate or delay polymorphonuclear leukocyte apoptosis in vitro. | 2001 | J. Periodontol. | pmid:11525438 |
Dongmo AB et al. | Anti-inflammatory and analgesic properties of the stem bark extracts of Erythrophleum suaveolens (Caesalpiniaceae), Guillemin & Perrottet. | 2001 | J Ethnopharmacol | pmid:11535356 |
Davido DJ et al. | Butyrate and propionate downregulate ERK phosphorylation in HT-29 colon carcinoma cells prior to differentiation. | 2001 | Eur. J. Cancer Prev. | pmid:11535873 |
Khan MR et al. | Antimicrobial activity of Lithocarpus celebicus. | 2001 | Fitoterapia | pmid:11543975 |
Shin HS et al. | Performance of UASB reactor treating leachate from acidogenic fermenter in the two-phase anaerobic digestion of food waste. | 2001 | Water Res. | pmid:11547866 |
Shimada N et al. | Alterations of gene expression in endoderm differentiation of F9 teratocarcinoma cells. | 2001 | Mol. Reprod. Dev. | pmid:11553914 |
Lal S et al. | Vagal afferent responses to fatty acids of different chain length in the rat. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11557510 |
Kiela PR et al. | Regulation of the rat NHE3 gene promoter by sodium butyrate. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11557515 |
Ochiai K et al. | Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557577 |
Yu HQ and Fang HH | Acidification of mid- and high-strength dairy wastewaters. | 2001 | Water Res. | pmid:11561632 |
Jung M | Inhibitors of histone deacetylase as new anticancer agents. | 2001 | Curr. Med. Chem. | pmid:11562279 |
Martin C et al. | Comparison of non-tracer and tracer methods for determination of volatile fatty acid production rate in the rumen of sheep fed on two levels of intake. | 2001 | Br. J. Nutr. | pmid:11570985 |
Mohiuddin I et al. | Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma. | 2001 | Cancer Gene Ther. | pmid:11571532 |
Yin L et al. | Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. | 2001 | J. Biol. Chem. | pmid:11572859 |
Lührs H et al. | Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells. | 2001 | Dig. Dis. Sci. | pmid:11575451 |
Leng SL et al. | Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. | 2001 | Carcinogenesis | pmid:11577001 |
Rosignoli P et al. | Protective activity of butyrate on hydrogen peroxide-induced DNA damage in isolated human colonocytes and HT29 tumour cells. | 2001 | Carcinogenesis | pmid:11577008 |
Shiau MY et al. | Establishment of a consistent L929 bioassay system for TNF-alpha quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells. | 2001 | Mediators Inflamm. | pmid:11577996 |
Kristensen NB | Rumen microbial sequestration of [2-(13)C]acetate in cattle. | 2001 | J. Anim. Sci. | pmid:11583438 |
Lee GS et al. | Layer-by-layer assembly of zeolite crystals on glass with polyelectrolytes as ionic linkers. | 2001 | J. Am. Chem. Soc. | pmid:11583538 |
Cummins CL et al. | Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. | 2001 | Pharm. Res. | pmid:11587480 |
Kim DY et al. | Biosynthesis of polyhydroxyalkanoate copolyester containing cyclohexyl groups by Pseudomonas oleovorans. | 2001 | Int. J. Biol. Macromol. | pmid:11589966 |
Chen Z et al. | Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. | 1999 | Chin. Med. J. | pmid:11593538 |
Bernhard D et al. | Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. | 2001 | Cell Death Differ. | pmid:11598799 |
Zhang WL et al. | Induction of heat shock proteins and its effects on glial differentiation in rat C6 glioblastoma cells. | 2001 | Kobe J Med Sci | pmid:11599126 |
Takahashi A et al. | Chloride secretion induced by thermostable direct haemolysin of Vibrio parahaemolyticus depends on colonic cell maturation. | 2001 | J. Med. Microbiol. | pmid:11599736 |
Lee YJ et al. | Effect of iron concentration on hydrogen fermentation. | 2001 | Bioresour. Technol. | pmid:11601547 |
Combourieu B et al. | Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations. | 2001 | Drug Metab. Dispos. | pmid:11602519 |
Gandolfi R et al. | Efficient and selective microbial esterification with dry mycelium of Rhizopus oryzae. | 2001 | J. Biotechnol. | pmid:11604169 |
Tsai MH et al. | Effect of platelet activating factor and butyrate on the expression of interleukin-2 receptor alpha in nasopharyngeal carcinoma cells. | 2001 | Int. J. Oncol. | pmid:11605008 |
Terao Y et al. | Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells. | 2001 | Int. J. Cancer | pmid:11668507 |
Tsapali DS et al. | mRNA levels of the differentiation-associated linker histone variant H1 zero in mitotically active and postmitotic senescent human diploid fibroblast cell populations. | 2001 | Exp. Gerontol. | pmid:11672986 |
Gaschott T et al. | Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11676498 |
Onori L et al. | N-Butyrate rectal transport in cirrhotic patients. | 2001 | Dig. Dis. Sci. | pmid:11680580 |
Fujita M et al. | Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. | 2001 | Cancer Res. | pmid:11691783 |
Sultanova N et al. | Antioxidant and antimicrobial activities of Tamarix ramosissima. | 2001 | J Ethnopharmacol | pmid:11694365 |
Zheng X et al. | Synergistic effects of clinically achievable concentrations of 12-O-tetradecanoylphorbol-13-acetate in combination with all-trans retinoic acid, 1alpha,25-dihydroxyvitamin D3, and sodium butyrate on differentiation in HL-60 cells. | 2000 | Oncol. Res. | pmid:11697820 |
Amano J et al. | Comparative study of glycosyltransferase activities in Caco-2 cells before and after enterocytic differentiation using lectin-affinity high-performance liquid chromatography. | 2001 | Arch. Biochem. Biophys. | pmid:11697856 |
Resta-Lenert S et al. | Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11698242 |
Loffing-Cueni D et al. | Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11698247 |
Dunphy CH et al. | Acute promyelocytic leukemia, hypogranular variant, with uncharacteristic staining with chloroacetate esterase. | 2001 | Leuk. Lymphoma | pmid:11699210 |
Santini V et al. | Searching for the magic bullet against cancer: the butyrate saga. | 2001 | Leuk. Lymphoma | pmid:11699392 |
Amin HM et al. | Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). | 2001 | Br. J. Haematol. | pmid:11703323 |
Gassull MA and Cabré E | Nutrition in inflammatory bowel disease. | 2001 | Curr Opin Clin Nutr Metab Care | pmid:11706295 |
Frederich M and Balschi JA | The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart. | 2002 | J. Biol. Chem. | pmid:11707445 |
Pérez G et al. | Disturbance of cellular iron uptake and utilisation by aluminium. | 2001 | J. Inorg. Biochem. | pmid:11709209 |
Tuleu C et al. | Colonic delivery of sodium butyrate via oral route: acrylic coating design of pellets and in vivo evaluation in rats. | 2001 | Methods Find Exp Clin Pharmacol | pmid:11712644 |