| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Herpesviridae Infections | D006566 | 4 associated lipids |
| Hydatidiform Mole | D006828 | 3 associated lipids |
| Hyperkinesis | D006948 | 11 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Infectious Mononucleosis | D007244 | 5 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Intestinal Neoplasms | D007414 | 2 associated lipids |
| Ketosis | D007662 | 13 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Belcheva MM et al. | Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone. | 1991 | J. Pharmacol. Exp. Ther. | pmid:1656025 |
| Palermo DP et al. | Production of analytical quantities of recombinant proteins in Chinese hamster ovary cells using sodium butyrate to elevate gene expression. | 1991 | J. Biotechnol. | pmid:1369310 |
| Chen CY et al. | Regulatory sequences controlling short chain fatty acid metabolism in Escherichia coli. | 1991 | SAAS Bull. Biochem. Biotechnol. | pmid:1369456 |
| Mascolo N et al. | Mechanism of short-chain fatty acid uptake by apical membrane vesicles of rat distal colon. | 1991 | Gastroenterology | pmid:2065907 |
| Streutker C and Drucker DJ | Rapid induction of parathyroid hormone-like peptide gene expression by sodium butyrate in a rat islet cell line. | 1991 | Mol. Endocrinol. | pmid:2072929 |
| Rezanka T et al. | Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. | 1991 | FEMS Microbiol. Lett. | pmid:1769552 |
| Church DL et al. | Physiological effects of metronidazole on Clostridium pasteurianum. | 1991 | J. Antimicrob. Chemother. | pmid:1778853 |
| Breuer RI et al. | Rectal irrigation with short-chain fatty acids for distal ulcerative colitis. Preliminary report. | 1991 | Dig. Dis. Sci. | pmid:1988261 |
| Rephaeli A et al. | Derivatives of butyric acid as potential anti-neoplastic agents. | 1991 | Int. J. Cancer | pmid:1874573 |
| He RY and Breitman TR | Retinoic acid inhibits sodium butyrate-induced monocytic differentiation of HL60 cells while synergistically inducing granulocytoid differentiation. | 1991 | Eur. J. Haematol. | pmid:1995327 |
| Latella G and Caprilli R | Metabolism of large bowel mucosa in health and disease. | 1991 | Int J Colorectal Dis | pmid:1875122 |
| Thomas DJ et al. | Effect of sodium butyrate on metallothionein induction and cadmium cytotoxicity in ROS 17/2.8 cells. | 1991 | Toxicology | pmid:1996466 |
| Glauber JG et al. | 5'-flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells. | 1991 | Mol. Cell. Biol. | pmid:1875947 |
| Hendzel MJ and Davie JR | Dynamically acetylated histones of chicken erythrocytes are selectively methylated. | 1991 | Biochem. J. | pmid:1996971 |
| Lewandowski ED et al. | NMR studies of beta-oxidation and short-chain fatty acid metabolism during recovery of reperfused hearts. | 1991 | Am. J. Physiol. | pmid:1877663 |
| Mullins TD et al. | Ultrastructural differentiation of sodium butyrate-treated human pancreatic adenocarcinoma cell lines. | 1991 | Pancreas | pmid:1946315 |
| Demigné C et al. | Interactions between propionate and amino acid metabolism in isolated sheep hepatocytes. | 1991 | Br. J. Nutr. | pmid:2043606 |
| Gálfi P et al. | The inhibitory action of sodium butyrate on the growth of KB, MMT and RPMI cells. | 1991 | Vet. Res. Commun. | pmid:1949598 |
| Kondoh N et al. | Effects of sodium butyrate on the rearranged c-myc expression in mouse plasmacytoma cells. | 1991 | Exp. Cell Res. | pmid:1879469 |
| Higgins PJ and Ryan MP | p52(PAI-1) and actin expression in butyrate-induced flat revertants of v-ras-transformed rat kidney cells. | 1991 | Biochem. J. | pmid:1953684 |
| Deng MH et al. | Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate. | 1991 | Brain Res. | pmid:1802344 |
| Saito S et al. | Flow cytometric and biochemical analysis of dose-dependent effects of sodium butyrate on human endometrial adenocarcinoma cells. | 1991 | Cytometry | pmid:1794255 |
| Munks RJ et al. | Histone H4 acetylation in Drosophila. Frequency of acetylation at different sites defined by immunolabelling with site-specific antibodies. | 1991 | FEBS Lett. | pmid:2060643 |
| Tsukamoto A and Kaneko Y | Novobiocin and butyrate synergistically enhanced cytokeratin assembly and acetate uptake of human liver cells. | 1991 | Cell Biol. Int. Rep. | pmid:1723029 |
| Tanaka J et al. | Sodium butyrate-inducible replication of human cytomegalovirus in a human epithelial cell line. | 1991 | Virology | pmid:1656587 |
| Nuebling CM and Mueller-Lantzsch N | Identification of the gene product encoded by the PstI repeats (IR4) of the Epstein-Barr virus genome. | 1991 | Virology | pmid:1656605 |
| Tonetti M et al. | Intracellular pH regulates the production of different oxygen metabolites in neutrophils: effects of organic acids produced by anaerobic bacteria. | 1991 | J. Leukoc. Biol. | pmid:1846905 |
| McIntyre A et al. | Different fibers have different regional effects on luminal contents of rat colon. | 1991 | Gastroenterology | pmid:1657677 |
| Donadel G et al. | Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells. | 1991 | Eur. J. Biochem. | pmid:1847869 |
| Gossen D et al. | Characterization and regulation of the expression of scyllatoxin (Leiurotoxin I) receptors in the human neuroblastoma cell line NB-OK 1. | 1991 | FEBS Lett. | pmid:1855593 |
| Klebe RJ et al. | Quantitative assay for morphogenesis indicates the role of extracellular matrix components and G proteins. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1658786 |
| PospÃsil S | Resistance of Streptomyces cinnamonensis to butyrate and isobutyrate: production and properties of a new anti-isobutyrate (AIB) factor. | 1991 | J. Gen. Microbiol. | pmid:1748869 |
| Krajewski WA and Luchnik AN | High rotational mobility of DNA in animal cells and its modulation by histone acetylation. | 1991 | Mol. Gen. Genet. | pmid:1661371 |
| Sturm RA et al. | A melanoma octamer binding protein is responsive to differentiating agents. | 1991 | Cell Growth Differ. | pmid:1751407 |
| Krajewski WA and Luchnik AN | Relationship of histone acetylation to DNA topology and transcription. | 1991 | Mol. Gen. Genet. | pmid:1662766 |
| Weinberg JM et al. | Metabolic aspects of protection by glycine against hypoxic injury to isolated proximal tubules. | 1991 | J. Am. Soc. Nephrol. | pmid:1883965 |
| Perry CA and Annunziato AT | Histone acetylation reduces H1-mediated nucleosome interactions during chromatin assembly. | 1991 | Exp. Cell Res. | pmid:1893943 |
| Hay FG et al. | Modulation of the cluster 1 and mucin antigens in human small cell lung cancer and other epithelial tumour cell lines after treatment with the differentiation inducing agent, sodium butyrate. | 1991 | Br. J. Cancer Suppl. | pmid:1645568 |
| Nakai T et al. | Drug effects on CA125 antigen expression and antibody binding to cancer cells. | 1991 | Int. J. Cancer | pmid:1645702 |
| Arao Y et al. | Reactivatable latency of three avirulent strains of herpes simplex virus type 1 after intranasal inoculation in mice. | 1991 | Acta Med. Okayama | pmid:1648298 |
| Granitzer M and Steels P | Role of Na+/K+ exchange and organic acids in base induced hyperpolarization of renal proximal amphibian tubule. | 1991 | Biochim. Biophys. Acta | pmid:1648393 |
| Mitsui K et al. | Multiple neurite formation in neuroblastoma cell lines by griseolic acid, a potent inhibitor of cyclic nucleotide phosphodiesterases. | 1991 | J. Neurochem. | pmid:1649254 |
| Levine A et al. | Inhibition of promoter activity by methylation: possible involvement of protein mediators. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1650472 |
| Uenoyama Y et al. | Dibutyryl cyclic AMP induces formyl peptide receptor expression and chemotactic responses in a human eosinophilic cell line, EoL-1. | 1991 | Exp. Hematol. | pmid:1651253 |
| O'Shea JJ et al. | Expression of v-src in a murine T-cell hybridoma results in constitutive T-cell receptor phosphorylation and interleukin 2 production. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2000381 |
| Kosaka M et al. | Reversible effects of sodium butyrate on the differentiation of F9 embryonal carcinoma cells. | 1991 | Exp. Cell Res. | pmid:1898593 |
| Sandvig K et al. | Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells. | 1991 | J. Cell Biol. | pmid:1901867 |
| Fleming SE et al. | Nutrient utilization by cells isolated from rat jejunum, cecum and colon. | 1991 | J. Nutr. | pmid:1903440 |
| Goya L and Timiras PS | Characterization of nuclear T3 receptors in human neuroblastoma cells SH-SY5Y: effect of differentiation with sodium butyrate and nerve growth factor. | 1991 | Neurochem. Res. | pmid:1679204 |
| Tisdale EJ et al. | Sodium butyrate causes reexpression of three membrane proteins on glycolipid-anchoring mutants. | 1991 | Somat. Cell Mol. Genet. | pmid:1679568 |
| Golub EI et al. | Induction of dormant HIV-1 by sodium butyrate: involvement of the TATA box in the activation of the HIV-1 promoter. | 1991 | AIDS | pmid:1883541 |
| Shubhada S and Tsai YH | Differential effects of FSH on the activities of S-adenosyl-L-methionine decarboxylase and ornithine decarboxylase in Rat sertoli cells. | 1990 Sep-Oct | J. Androl. | pmid:2174845 |
| McGarvey TW et al. | The effect of butyric acid and retinoic acid on invasion and experimental metastasis of murine melanoma cells. | 1990 Sep-Oct | Clin. Exp. Metastasis | pmid:2390813 |
| Sankaranarayanan K et al. | Effects of sodium butyrate on X-ray and bleomycin-induced chromosome aberrations in human peripheral blood lymphocytes. | 1990 Oct-Dec | Genet. Res. | pmid:1703101 |
| Gabius S et al. | Regulation of distribution, amount and ligand affinity of sugar receptors in human colon carcinoma cells by treatment with sodium butyrate, retinoic acid and phorbol ester. | 1990 Jul-Aug | Anticancer Res. | pmid:2382971 |
| Yusta B et al. | Regulation of thyroid hormone receptor and c-erbA mRNA levels by butyrate in neuroblastoma (N2A) and glioma (C6) cells. | 1990 | J. Neurosci. Res. | pmid:1979350 |
| Murphy LD et al. | Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines. | 1990 | Cancer Commun. | pmid:2206777 |
| Staiano-Coico L et al. | Epidermal cell-shape regulation and subpopulation kinetics during butyrate-induced terminal maturation of normal and SV40-transformed human keratinocytes: epithelial models of differentiation therapy. | 1990 | Int. J. Cancer | pmid:2210888 |
| Lazar MA | Sodium butyrate selectively alters thyroid hormone receptor gene expression in GH3 cells. | 1990 | J. Biol. Chem. | pmid:2211641 |
| Guilbaud NF et al. | Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells. | 1990 | J. Cell. Physiol. | pmid:2211839 |
| McDevitt J et al. | Urinary organic acid profiles in fatty Zucker rats: indications for impaired oxidation of butyrate and hexanoate. | 1990 | Metab. Clin. Exp. | pmid:2215249 |
| Järvinen M | Vimentin in human erythroleukemia (HEL) cells is modulated with differentiation inducers. | 1990 | Cell Biol. Int. Rep. | pmid:2188740 |
| Marchetti P et al. | Diurnal pattern of plasma metformin concentrations and its relation to metabolic effects in type 2 (non-insulin-dependent) diabetic patients. | 1990 | Diabete Metab | pmid:2086278 |
| Trautmann ME et al. | Inverse relationship between glucose metabolism and glucose-induced insulin secretion in rat insulinoma cells. | 1990 | Horm. Res. | pmid:2097293 |
| Cary JW et al. | Cloning and expression of Clostridium acetobutylicum ATCC 824 acetoacetyl-coenzyme A:acetate/butyrate:coenzyme A-transferase in Escherichia coli. | 1990 | Appl. Environ. Microbiol. | pmid:2383002 |
| Breitman TR and He RY | Combinations of retinoic acid with either sodium butyrate, dimethyl sulfoxide, or hexamethylene bisacetamide synergistically induce differentiation of the human myeloid leukemia cell line HL60. | 1990 | Cancer Res. | pmid:2400989 |
| Gálfi P and Bokori J | Feeding trial in pigs with a diet containing sodium n-butyrate. | 1990 | Acta Vet. Hung. | pmid:2100936 |
| Waterborg JH et al. | Dynamic histone acetylation in alfalfa cells. Butyrate interference with acetate labeling. | 1990 | Biochim. Biophys. Acta | pmid:2383588 |
| Chou JY et al. | Effects of sodium butyrate on the synthesis of human pregnancy-specific beta 1-glycoprotein. | 1990 | J. Biol. Chem. | pmid:2341406 |
| Coscia CJ et al. | Effects of up-regulation by butyrate on delta opioid receptor GTP sensitivity and distribution in subcellular compartments. | 1990 | Prog. Clin. Biol. Res. | pmid:2154771 |
| Hwang GY et al. | Chromatographic purification and characterization of EBV DNase from chemically induced lymphoid cells. | 1990 | Virology | pmid:2155513 |
| Perrine SP | Pharmacologic modulation of fetal globin gene expression in the perinatal period. | 1990 | Semin. Perinatol. | pmid:1705052 |
| Perrine SP et al. | Stopping the biologic clock for globin gene switching. | 1990 | Ann. N. Y. Acad. Sci. | pmid:1705405 |
| Takahashi H and Parsons PG | In vitro phenotypic alteration of human melanoma cells induced by differentiating agents: heterogeneous effects on cellular growth and morphology, enzymatic activity, and antigenic expression. | 1990 | Pigment Cell Res. | pmid:1710361 |
| Constantoulakis P et al. | A transgenic mouse model for studying the induction of fetal hemoglobin in the adult. | 1990 | Trans. Assoc. Am. Physicians | pmid:1721467 |
| Williams AC et al. | Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence. | 1990 | Cancer Res. | pmid:2369746 |
| Zhang JW et al. | Butyrate induces expression of transfected human fetal and endogenous mouse embryonic globin genes in GM 979 erythroleukemia cells. | 1990 | Dev. Genet. | pmid:2379328 |
| Martin RL et al. | Characterisation of putrescine uptake by cultured adult mouse hepatocytes. | 1990 | Biochim. Biophys. Acta | pmid:2297540 |
| Staiano-Coico L et al. | TGF-alpha and TGF-beta expression during sodium-N-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of TGF-beta mRNA in suprabasal cells. | 1990 | Exp. Cell Res. | pmid:2257881 |
| Davidson AM and Halestrap AP | Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms. | 1990 | Biochem. J. | pmid:2344354 |
| Kim RY and Stern WH | Retinoids and butyrate modulate fibroblast growth and contraction of collagen matrices. | 1990 | Invest. Ophthalmol. Vis. Sci. | pmid:2354920 |
| Natke E | Cell volume regulation of rabbit cortical collecting tubule in anisotonic media. | 1990 | Am. J. Physiol. | pmid:2360659 |
| Thakur MK and Prasad S | ADP-ribosylation of HMG proteins and its modulation by different effectors in the liver of aging rats. | 1990 | Mech. Ageing Dev. | pmid:2325444 |
| Rius C et al. | The induction of vimentin gene expression by sodium butyrate in human promonocytic leukemia U937 cells. | 1990 | Exp. Cell Res. | pmid:2328771 |
| Herz F and Halwer M | Differential effects of sodium butyrate and hyperosmolality on the modulation of alkaline phosphatases of LoVo cells. | 1990 | Exp. Cell Res. | pmid:2328777 |
| Doi Y et al. | Cyclic nature of poly(3-hydroxyalkanoate) metabolism in Alcaligenes eutrophus. | 1990 | FEMS Microbiol. Lett. | pmid:2328906 |
| Saito S et al. | [Quenching effect and analysis of cell proliferation in dual-laser flow cytometry with human endometrial adenocarcinoma cells in vitro]. | 1990 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:2332670 |
| Chou JY and Zilberstein M | Expression of the pregnancy-specific beta 1-glycoprotein gene in cultured human trophoblasts. | 1990 | Endocrinology | pmid:2226305 |
| Oliva R et al. | Histone hyperacetylation can induce unfolding of the nucleosome core particle. | 1990 | Nucleic Acids Res. | pmid:2339060 |
| Tang DC and Taylor MW | Transcriptional activation of the adenine phosphoribosyltransferase promoter by an upstream butyrate-induced Moloney murine sarcoma virus enhancer-promoter element. | 1990 | J. Virol. | pmid:2159551 |
| Kocache MM and Pearson GR | Protein kinase activity associated with a cell cycle regulated, membrane-bound Epstein-Barr virus induced early antigen. | 1990 | Intervirology | pmid:2159954 |
| Bresnick EH et al. | Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2160080 |
| Wiechmann AF et al. | Cyclic AMP and butyrate modulate melatonin synthesis in Y79 human retinoblastoma cells. | 1990 | J. Neurochem. | pmid:2162375 |
| Prasad KN et al. | Decreased expressions of c-myc and H-ras oncogenes in vitamin E succinate induced morphologically differentiated murine B-16 melanoma cells in culture. | 1990 | Biochem. Cell Biol. | pmid:2177340 |
| Fischkoff SA and Rossi RM | Lineage directed HL-60 cell sublines as a model system for the study of early events in lineage determination of myeloid cells. | 1990 | Leuk. Res. | pmid:2177814 |
| Toscani A et al. | Sodium butyrate in combination with insulin or dexamethasone can terminally differentiate actively proliferating Swiss 3T3 cells into adipocytes. | 1990 | J. Biol. Chem. | pmid:2180933 |
| Gorisse MC et al. | Alterations of growth fraction and DNA content in K562 cells by differentiating agents. | 1990 | Cytometry | pmid:1980242 |
| Buscail L et al. | Divergent regulation of beta 2-adrenoceptors and adenylate cyclase in the Cyc- mouse T lymphoma cell line TL2-9. | 1990 | Immunobiology | pmid:1980264 |
| Shibata H et al. | Increase in the level of P-glycoprotein mRNA expression in multidrug-resistant K562 cell lines treated with sodium butyrate is not accompanied with erythroid differentiation. | 1990 | Jpn. J. Cancer Res. | pmid:1980493 |
| Ramp U et al. | Uniform response of c-raf expression to differentiation induction and inhibition of proliferation in a rat rhabdomyosarcoma cell line. | 1990 | Virchows Arch., B, Cell Pathol. | pmid:1980557 |