butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Oshitari T et al. | Endoplasmic reticulum stress and diabetic retinopathy. | 2008 | Vasc Health Risk Manag | pmid:18629365 |
Wang Y et al. | Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. | Ultrastruct Pathol | pmid:27158913 | |
Kalachniuk GI et al. | [Glutamine metabolism by rumen microorganisms: effect of monensin]. | 1992 Jul-Aug | Ukr. Biokhim. Zh. | pmid:1360177 |
Reznikov AG | [Determination of progesterone and delta 4-pregnen-20 alpha-ol-3-one contents in ovaries with two-dimensional thin-layer chromatography and spectrofluorimetry]. | 1978 May-Jun | Ukr. Biokhim. Zh. | pmid:664052 |
Hrynevych IuP et al. | [Antioxidant properties of rhenium cluster complexes with butyric acid derivatives in blood plasma and erythrocytes]. | 2003 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:14574740 |
Okamoto T | [Positive and negative regulation of transcription from HIV provirus]. | 2011 | Uirusu | pmid:21972559 |
Lauricella M et al. | Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells. | 1998 | Tumour Biol. | pmid:9701726 |
Lauricella M et al. | Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells. | 2000 Nov-Dec | Tumour Biol. | pmid:11006574 |
Kéri G et al. | Comparison of the tyrosine kinase activity with the proliferation rate in human colon solid tumors and tumor cell lines. | 1988 | Tumour Biol. | pmid:3206110 |
Williams KJ et al. | The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. | 2011 | Tuberculosis (Edinb) | pmid:21764638 |
Abramian DS et al. | [Agents that act on chromatin structure affect the rate of intrachromosomal homologous DNA recombination in cultured cells]. | 1994 | Tsitologiia | pmid:7701620 |
Glebov OK et al. | [The effect of sodium butyrate and luminol on reciprocal exchanges and gene conversion during extrachromosomal DNA recombination in cultured animal cells]. | 1994 | Tsitologiia | pmid:7809980 |
Nikiforov AA et al. | [UV-induced immobilization of DNA repair protein XPA in different human cell line]. | 2000 | Tsitologiia | pmid:10752124 |
Tigunova EA et al. | [Alternative type of fuel--biobutanol]. | 2013 Nov-Dec | Tsitol. Genet. | pmid:24437198 |
Mullai K and Jebanesan A | Larvicidal, ovicidal and repellent activities of the leaf extract of two cucurbitacious plants against filarial vector Culex quinquefasciatus (Say) (Diptera : Culicidae). | 2007 | Trop Biomed | pmid:17568371 |
Chakeredza S et al. | Ruminal fermentation kinetics in ewes offered a maize stover basal diet supplemented with cowpea hay, groundnut hay, cotton seed meal or maize meal. | 2002 | Trop Anim Health Prod | pmid:12094677 |
Emaga TH et al. | Ripening influences banana and plantain peels composition and energy content. | 2011 | Trop Anim Health Prod | pmid:20725857 |
Krishna S et al. | Artemisinins: their growing importance in medicine. | 2008 | Trends Pharmacol. Sci. | pmid:18752857 |
Krokowicz L et al. | Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea: a randomized prospective study. | Travel Med Infect Dis | pmid:24063909 | |
Böhmig GA et al. | Induction of alloantigen-specific hyporesponsiveness in vitro by the short-chain fatty acid N-butyrate. | 1995 | Transplantation | pmid:7539556 |
Lopez-Avalos MD et al. | Enhanced maturation of porcine neonatal pancreatic cell clusters with growth factors fails to improve transplantation outcome. | 2001 | Transplantation | pmid:11374418 |
Perez RV et al. | Selective targeting of Kupffer cells with liposomal butyrate augments portal venous transfusion-induced immunosuppression. | 1998 | Transplantation | pmid:9625008 |
Otonkoski T et al. | Nicotinamide and sodium butyrate for the induction of fetal porcine beta-cell differentiation prior to transplantation. | 1997 | Transplant. Proc. | pmid:9193518 |
McLear M et al. | Porcine islet function: effects of arginine, leucine, and butyrate. | 1992 | Transplant. Proc. | pmid:1604696 |
Böhmig GA et al. | Induction of alloantigen-specific hyporesponsiveness in vitro by n-butyrate: antagonistic effect of cyclosporin A. | 1996 | Transpl. Int. | pmid:8959855 |
Sayasone S et al. | Diversity of human intestinal helminthiasis in Lao PDR. | 2009 | Trans. R. Soc. Trop. Med. Hyg. | pmid:19038411 |
Constantoulakis P et al. | A transgenic mouse model for studying the induction of fetal hemoglobin in the adult. | 1990 | Trans. Assoc. Am. Physicians | pmid:1721467 |
Schüller S | Shiga toxin interaction with human intestinal epithelium. | 2011 | Toxins (Basel) | pmid:22069729 |
Kopic S and Geibel JP | Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection. | 2010 | Toxins (Basel) | pmid:22069677 |
Jeng JH et al. | Toxic and metabolic effect of sodium butyrate on SAS tongue cancer cells: role of cell cycle deregulation and redox changes. | 2006 | Toxicology | pmid:16737765 |
Thomas DJ et al. | Effect of sodium butyrate on metallothionein induction and cadmium cytotoxicity in ROS 17/2.8 cells. | 1991 | Toxicology | pmid:1996466 |
Scharmach E et al. | Glutathione S-transferase expression and isoenzyme composition during cell differentiation of Caco-2 cells. | 2009 | Toxicology | pmid:19800383 |
Ridd K et al. | Foetal rat lung epithelial (FRLE) cells: alterations in cellular homeostasis and gene expression in response to etoposide, hydrogen peroxide and sodium butyrate. | 2004 | Toxicology | pmid:14751676 |
Peleran JC et al. | Identification of the cooked food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and its N-acetylated and 3-N-demethylated metabolites in rat urine. | 1987 | Toxicology | pmid:3810661 |
Morris JB and Hubbs AF | Inhalation dosimetry of diacetyl and butyric acid, two components of butter flavoring vapors. | 2009 | Toxicol. Sci. | pmid:18940962 |
Krig SR and Rice RH | TCDD suppression of tissue transglutaminase stimulation by retinoids in malignant human keratinocytes. | 2000 | Toxicol. Sci. | pmid:10910994 |
Jergil M et al. | Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells. | 2011 | Toxicol. Sci. | pmid:21427059 |
Di Renzo F et al. | Relationship between embryonic histonic hyperacetylation and axial skeletal defects in mouse exposed to the three HDAC inhibitors apicidin, MS-275, and sodium butyrate. | 2007 | Toxicol. Sci. | pmid:17517827 |
Knoll N et al. | Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate. | 2005 | Toxicol. Sci. | pmid:15829614 |
Barton HA et al. | Family approach for estimating reference concentrations/doses for series of related organic chemicals. | 2000 | Toxicol. Sci. | pmid:10746952 |
Teeguarden JG et al. | Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid. | 2005 | Toxicol. Sci. | pmid:15703268 |
Lu H et al. | Sodium butyrate potentiates carbon tetrachloride-induced acute liver injury in mice. | 2012 | Toxicol. Mech. Methods | pmid:22871220 |
Yang CH et al. | Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats. | 2009 | Toxicol. Lett. | pmid:19616083 |
Chapkin RS et al. | Effect of diet on colonic-programmed cell death: molecular mechanism of action. | 2000 | Toxicol. Lett. | pmid:10720760 |
Waalkes MP and Wilson MJ | Enhancement of cadmium-induced metallothionein synthesis in cultured TRL 1215 cells by butyric acid pretreatment. | 1986 | Toxicol. Lett. | pmid:3775811 |
Yi Z et al. | Inhibitory effect of tellimagrandin I on chemically induced differentiation of human leukemia K562 cells. | 2004 | Toxicol. Lett. | pmid:14757314 |
Sharma B and Sharma PM | Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23921152 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Koestner A | Prognostic role of cell morphology of animal tumors. | 1985 | Toxicol Pathol | pmid:4048772 |