| MeSH term | MeSH ID | Detail |
|---|---|---|
| Retinal Neoplasms | D019572 | 3 associated lipids |
| Epstein-Barr Virus Infections | D020031 | 3 associated lipids |
| Enterocolitis, Necrotizing | D020345 | 3 associated lipids |
| Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
| Genomic Instability | D042822 | 7 associated lipids |
| Diverticulosis, Colonic | D043963 | 1 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Urea Cycle Disorders, Inborn | D056806 | 2 associated lipids |
| Prostatic Neoplasms, Castration-Resistant | D064129 | 3 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Haag MM et al. | Reverse transformation and genome exposure in the C6 glial tumor cell line. | 1994 | Cancer Invest. | pmid:8281464 |
| Fürll M et al. | [Effect of a three-week butyric acid exposure on the mineral metabolism and the skeletal system in cattle]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267564 |
| Fürll M et al. | [Hormonal reactions in fattening bulls and cows during a three-week butyric acid exposure]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267563 |
| Stark AH and Madar Z | In vitro production of short-chain fatty acids by bacterial fermentation of dietary fiber compared with effects of those fibers on hepatic sterol synthesis in rats. | 1993 | J. Nutr. | pmid:8263612 |
| Karuri AR et al. | Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment. | 1993 | Br. J. Cancer | pmid:8260358 |
| Perry CA et al. | Parental nucleosomes segregated to newly replicated chromatin are underacetylated relative to those assembled de novo. | 1993 | Biochemistry | pmid:8257695 |
| Planchon P et al. | Differential elimination of synthetic butyric triglycerides in vivo: a pharmacokinetic study. | 1993 | J Pharm Sci | pmid:8254490 |
| Halvorsen YD et al. | Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes. | 1993 | J. Clin. Invest. | pmid:8254042 |
| Roediger WE | Colonic epithelial metabolism in ulcerative colitis. | 1993 | Gut | pmid:8244158 |
| Finnie IA et al. | Ileal and colonic epithelial metabolism in quiescent ulcerative colitis: increased glutamine metabolism in distal colon but no defect in butyrate metabolism. | 1993 | Gut | pmid:8244143 |
| Piñeiro M et al. | Transcription of mononucleosomal particles acetylated in the presence of n-butyrate. | 1993 | Mol. Biol. Rep. | pmid:8232292 |
| Dimitrov S et al. | Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type. | 1993 | Dev. Biol. | pmid:8224538 |
| Musk SR and Johnson IT | Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29. | 1993 | Carcinogenesis | pmid:8222057 |
| Gope R and Gope ML | Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29. | 1993 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:8220069 |
| Nakai T et al. | Changes in CA125 release and surface expression caused by drugs in uterine cervix adenocarcinoma cells. | 1993 | Ann Nucl Med | pmid:8217487 |
| Gürtler H et al. | Acute metabolic and hormonal effects of intravenously administered sodium n-butyrate in untreated and alloxan-diabetic sheep. | 1993 | Zentralbl Veterinarmed A | pmid:8212952 |
| Cairns SP and Dulhunty AF | Beta-adrenoceptor activation shows high-frequency fatigue in skeletal muscle fibers of the rat. | 1994 | Am. J. Physiol. | pmid:8203484 |
| Sheikh MS et al. | Expression of estrogen receptors in estrogen receptor-negative human breast carcinoma cells: modulation of epidermal growth factor-receptor (EGF-R) and transforming growth factor alpha (TGF alpha) gene expression. | 1994 | J. Cell. Biochem. | pmid:8200909 |
| Barratt MJ et al. | Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8197135 |
| Ogryzko VV et al. | Dissociation of retinoblastoma gene protein hyperphosphorylation and commitment to enter S phase. | 1994 | J. Virol. | pmid:8189510 |
| Goh SH et al. | Inhibition of tumour promotion by various palm-oil tocotrienols. | 1994 | Int. J. Cancer | pmid:8181855 |
| Ghibelli L et al. | A protein produced by a monocytic human cell line can induce apoptosis on tumor cells. | 1994 | FEBS Lett. | pmid:8181560 |
| Duman RS et al. | Induction of beta 2-adrenergic receptor mRNA and ligand binding in HeLa cells. | 1994 | J. Recept. Res. | pmid:8158578 |
| Schlake T et al. | Gene expression within a chromatin domain: the role of core histone hyperacetylation. | 1994 | Biochemistry | pmid:8155635 |
| Higgins PJ and Lipkin M | Expression of plasminogen activator inhibitor type 1 (PAI-1) by HT-29di human large bowel carcinoma cells is modulated as a function of epithelial differentiation. | 1994 | Cancer Lett. | pmid:8149346 |
| Boffa LC et al. | Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate. | 1994 | Exp. Cell Res. | pmid:8143791 |
| Honda J et al. | Spectroscopic observation of the intramolecular electron transfer in the photoactivation processes of nitrile hydratase. | 1994 | Biochemistry | pmid:8142355 |
| Lee S et al. | 1,25-Dihydroxyvitamin D3 and pancreatic beta-cell function: vitamin D receptors, gene expression, and insulin secretion. | 1994 | Endocrinology | pmid:8137721 |
| Morand C et al. | Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. | 1994 | Arch. Biochem. Biophys. | pmid:8135535 |
| Cann IK et al. | Effects of 3 chemical treatments on in vitro fermentation of rice straw by mixed rumen microbes in the presence or absence of anaerobic rumen fungi. | 1994 | Reprod. Nutr. Dev. | pmid:8129842 |
| Fedotov VP et al. | [The possible participation of gap junctions in the realization of the effects of stimulators of secretory processes in the hypophysis]. | 1993 | Biull Eksp Biol Med | pmid:8123822 |
| Krief S et al. | Transcriptional modulation by n-butyric acid of beta 1-, beta 2-, and beta 3-adrenergic receptor balance in 3T3-F442A adipocytes. | 1994 | J. Biol. Chem. | pmid:8120022 |
| Aviram A et al. | Comparison between the effect of butyric acid and its prodrug pivaloyloxymethylbutyrate on histones hyperacetylation in an HL-60 leukemic cell line. | 1994 | Int. J. Cancer | pmid:8119779 |
| Horvath PJ et al. | Differential effect of butyrate on lipids of human colon cancer cells. | 1993 | Nutr Cancer | pmid:8108277 |
| Frommel TO et al. | Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines. | 1993 | Int. J. Cancer | pmid:8103760 |
| Reeder JA et al. | Sodium butyrate differentially modulates plasminogen activator inhibitor type-1, urokinase plasminogen activator, and its receptor in a human colon carcinoma cell. | 1993 | Teratog., Carcinog. Mutagen. | pmid:8102211 |
| Oster T et al. | Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8099285 |
| VanderMeulen DL et al. | The identification of glioblastoma-associated, fucose-containing glycoproteins induced by retinoic acid. | 1994 Feb-Apr | Mol. Chem. Neuropathol. | pmid:8086041 |
| Illg DJ et al. | Effects of extruded soybeans and forage source on fermentation by rumen microorganisms in continuous culture. | 1994 | J. Dairy Sci. | pmid:8083419 |
| Schreck R et al. | Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines. | 1994 | J. Clin. Endocrinol. Metab. | pmid:8077363 |
| Austin C and Wray S | A quantitative study of the relation between intracellular pH and force in rat mesenteric vascular smooth muscle. | 1994 | Pflugers Arch. | pmid:8072846 |
| Chen H et al. | Characterization of two promoters of a rat pregnancy-specific glycoprotein gene. | 1994 | Biochemistry | pmid:8068638 |
| Wadee AA et al. | HLA expression in hepatocellular carcinoma cell lines. | 1994 | Clin. Exp. Immunol. | pmid:8050184 |
| Kaptein A et al. | Butyrate stimulates the secretion of apolipoprotein B-100-containing lipoproteins from HepG2 cells by inhibiting the intracellular degradation. | 1994 | Biochim. Biophys. Acta | pmid:8049249 |
| Peterec SM et al. | Butyrate modulates surfactant protein mRNA in fetal rat lung by altering mRNA transcription and stability. | 1994 | Am. J. Physiol. | pmid:8048547 |
| Frankel W et al. | Butyrate increases colonocyte protein synthesis in ulcerative colitis. | 1994 | J. Surg. Res. | pmid:8041140 |
| Shadan FF et al. | n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. | 1994 | J. Virol. | pmid:8035479 |
| Yamaguchi Y et al. | Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. | 1994 | J. Biol. Chem. | pmid:8034708 |
| Waagen V et al. | Homochiral glycerol derivatives by lipase-catalysed racemate resolution. | 1994 | Protein Eng. | pmid:8029217 |
| Sandvig K et al. | Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP. | 1994 | J. Cell Biol. | pmid:8027186 |
| Rydzyński K and Dalen H | Effect of sodium butyrate treatment on the granule morphology, histamine level and elemental content of the bone marrow-derived mast cell. | 1994 | Folia Histochem. Cytobiol. | pmid:8026597 |
| Chen ZX and Breitman TR | Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy. | 1994 | Cancer Res. | pmid:8012972 |
| Fariss MW et al. | The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds. | 1994 | Cancer Res. | pmid:8012947 |
| Walter KA et al. | Studies of recombinant Clostridium acetobutylicum with increased dosages of butyrate formation genes. | 1994 | Ann. N. Y. Acad. Sci. | pmid:8010698 |
| Sadaie MR and Hager GL | Induction of developmentally programmed cell death and activation of HIV by sodium butyrate. | 1994 | Virology | pmid:8009866 |
| Ebert PS and Salcman M | Differentiation therapy is potentiated by chemotherapy and hyperthermia in human and canine brain tumor cells in vitro. | 1994 | Neurosurgery | pmid:8008163 |
| Mullany P et al. | Genes encoding homologues of three consecutive enzymes in the butyrate/butanol-producing pathway of Clostridium acetobutylicum are clustered on the Clostridium difficile chromosome. | 1994 | FEMS Microbiol. Lett. | pmid:8001771 |
| Mannon PJ et al. | Characterization of a Y1-preferring NPY/PYY receptor in HT-29 cells. | 1994 | Am. J. Physiol. | pmid:7977753 |
| Bartram HP et al. | Antagonistic effects of deoxycholic acid and butyrate on epithelial cell proliferation in the proximal and distal human colon. | 1994 | Z Gastroenterol | pmid:7975774 |
| Fanti L et al. | Carnitine suppression of position-effect variegation in Drosophila melanogaster. | 1994 | Mol. Gen. Genet. | pmid:7969027 |
| Sun SH et al. | Effects of sodium butyrate on the transfer of arachidonic acid to phosphatidylcholine in a clonal oligodendrocyte cell line (CB-II). | 1994 | Lipids | pmid:7968267 |
| Coleman WB et al. | Development of dexamethasone-inducible tyrosine aminotransferase activity in WB-F344 rat liver epithelial stemlike cells cultured in the presence of sodium butyrate. | 1994 | J. Cell. Physiol. | pmid:7962128 |
| Chang AE | Perspectives on interleukin-2 immunotherapy for colon cancer. | 1994 | Gastroenterology | pmid:7958708 |
| Perrin P et al. | An interleukin 2/sodium butyrate combination as immunotherapy for rat colon cancer peritoneal carcinomatosis. | 1994 | Gastroenterology | pmid:7958681 |
| Almouzni G et al. | Histone acetylation influences both gene expression and development of Xenopus laevis. | 1994 | Dev. Biol. | pmid:7958429 |
| Tang MJ et al. | Expression and regulation of Na, K-ATPase in primary culture of proximal tubule cells. | 1994 | Chin J Physiol | pmid:7956509 |
| Schaffer JE and Lodish HF | Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. | 1994 | Cell | pmid:7954810 |
| Ohannesian DW et al. | Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate. | 1994 | Cancer Res. | pmid:7954433 |
| Matsunaga N et al. | Inhibitory effect of volatile fatty acids on GRF-induced GH secretion in sheep. | 1993 | Endocr. J. | pmid:7951518 |
| Nishii Y et al. | n-Butyrate enhances induction of thyroid hormone-responsive nuclear protein. | 1993 | Endocr. J. | pmid:7951517 |
| Safaya S et al. | Augmentation of gamma-globin gene promoter activity by carboxylic acids and components of the human beta-globin locus control region. | 1994 | Blood | pmid:7949149 |
| Gupta S et al. | Butyrate synchronization of hepatocytes: modulation of cycling and cell cycle regulated gene expression. | 1994 | Growth Factors | pmid:7946406 |
| Critchfield JW et al. | Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. | 1994 | Biochem. Pharmacol. | pmid:7945444 |
| Bode BP and Souba WW | Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. | 1994 | Ann. Surg. | pmid:7944654 |
| Pomponi MG and Neri G | Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. | 1994 | Am. J. Med. Genet. | pmid:7943015 |
| Swarovsky B et al. | Sodium butyrate induces neuroendocrine cytodifferentiation in the insulinoma cell line RINm5F. | 1994 | Pancreas | pmid:7937695 |
| Wu QH et al. | Replication of human cytomegalovirus in cells deficient in beta 2-microglobulin gene expression. | 1994 | J. Gen. Virol. | pmid:7931162 |
| Schroy PC et al. | Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells. | 1994 | J. Cell. Physiol. | pmid:7929596 |
| Katsarov V et al. | Effect of the butyric short-chain fatty acid on the intracranial pressure and EEG of rabbits. | 1993 | Folia Med (Plovdiv) | pmid:7927056 |
| Tang MJ and Tannen RL | Metabolic substrates alter attachment and differentiated functions of proximal tubule cell culture. | 1994 | J. Am. Soc. Nephrol. | pmid:7919143 |
| Papazafiri P et al. | Expression of muscle calsequestrin in epithelial HeLa cells: distribution and functional role. | 1994 | Biochim. Biophys. Acta | pmid:7918667 |
| Ho SB et al. | Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance. | 1994 | J. Cell. Physiol. | pmid:7913708 |
| Antoni BA et al. | NF-kappa B-dependent and -independent pathways of HIV activation in a chronically infected T cell line. | 1994 | Virology | pmid:7913275 |
| Arcus AC et al. | Studies with the autotransplanted ovine pancreas: glucagon and insulin secretion. | 1976 | Aust. J. Biol. Sci. | pmid:791227 |
| Morrow CS et al. | Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells. | 1994 | J. Biol. Chem. | pmid:7908296 |
| Corra S et al. | Modification of antigen expression in human and hamster pancreatic cancer cell lines induced by sodium butyrate. | 1993 | Teratog., Carcinog. Mutagen. | pmid:7905674 |
| D'Argenio G et al. | Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity. | 1994 | Gastroenterology | pmid:7905450 |
| Filippovich I et al. | Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of HSP70 mRNA. | 1994 | Biochem. Biophys. Res. Commun. | pmid:7904816 |
| Holtenius K and Hydbring E | Somatostatin inhibits butyrate-induced insulin secretion in sheep. | 1993 | Acta Vet Scand Suppl | pmid:7901983 |
| Soneoka Y et al. | A transient three-plasmid expression system for the production of high titer retroviral vectors. | 1995 | Nucleic Acids Res. | pmid:7899083 |
| Annunziato AT et al. | Relationship between methylation and acetylation of arginine-rich histones in cycling and arrested HeLa cells. | 1995 | Biochemistry | pmid:7893706 |
| Finnie IA et al. | Colonic mucin synthesis is increased by sodium butyrate. | 1995 | Gut | pmid:7890244 |
| Roediger WE and Millard S | Selective inhibition of fatty acid oxidation in colonocytes by ibuprofen: a cause of colitis? | 1995 | Gut | pmid:7890237 |
| Tune BM and Hsu CY | Toxicity of cephalosporins to fatty acid metabolism in rabbit renal cortical mitochondria. | 1995 | Biochem. Pharmacol. | pmid:7887988 |
| Higgins PJ et al. | Cell-shape-dependent modulation of p52(PAI-1) gene expression involves a secondary response pathway. | 1995 | Biochem. J. | pmid:7887903 |
| Stein J et al. | Mercaptopropionate inhibits butyrate uptake in isolated apical membrane vesicles of the rat distal colon. | 1995 | Gastroenterology | pmid:7875469 |
| Saito H et al. | Changes of antigen expression on human hepatoma cell lines caused by sodium butyrate, a differentiation inducer. | 1994 | J. Gastroenterol. | pmid:7874268 |
| Dang J et al. | Sodium butyrate inhibits expression of urokinase and its receptor mRNAs at both transcription and post-transcription levels in colon cancer cells. | 1995 | FEBS Lett. | pmid:7867787 |
| Blouin MJ et al. | Specialization switch in differentiating embryonic rat liver progenitor cells in response to sodium butyrate. | 1995 | Exp. Cell Res. | pmid:7867717 |
| Tang SJ et al. | Analysis of c-fos expression in the butyrate-induced F-98 glioma cell differentiation. | 1995 | Biochem. J. | pmid:7864828 |